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p-NPM (T199) Peptide

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 AP0100P100ulenquire
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Catalog No.AP0100P
Product Namep-NPM (T199) Peptide
ApplicationsBlocking
Alternative NameNucleophosmin; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin; NPM1; NPM
Swiss-ProtP06748
Product1 mg/ml in DI water.
Purification&PuritySynthetic peptide p-NPM (T199). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage&StabilityStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SpecificityThis peptide can be used with studies using AP0100 p-NPM (T199) pAb.

Background

Nucleophosmin (NPM; also known as B23, numatrin or NO38) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including assembly and transport of ribosomes, cytoplasmic/nuclear trafficking, regulation of DNA polymerase α activity, centrosome duplication and molecular chaperoning activities. The NPM gene is also known for its fusion with the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase. The NPM portion contributes to transformation by providing a dimerization domain, which results in activation of the fused kinase.

References for p-NPM (T199) Peptide

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