Contact us : info@bioworlde.com
Home > Product > Infectious disease series
Chapare mammarenavirus Nucleocapsid Protein(CHAPV-NP) NCP0167
  • Carrier:pET30a-CHAPV-NP-His(C-term) Virus:Chapare virus strain 810419 segment S, complete sequence
Product NameChapare mammarenavirus Nucleocapsid Protein(CHAPV-NP)
Catalog No.NCP0167
Swiss-ProtEU260463.1
Host His-tag
ReactivityE. coli Expression
ApplicationsSource of infection
Application_allReseach
BiowMW1686bp;47kDa
Purification&PurityTransferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
Browse similar products>>
Size Price
1mg $398
Add to cart My orders
Product Name :
Chapare mammarenavirus Nucleocapsid Protein(CHAPV-NP)
Background :
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
Product :
Soluble protein;PBS,PH=7.4
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
Immunogen :
pathway :
  • Carrier:pET30a-CHAPV-NP-His(C-term) Virus:Chapare virus strain 810419 segment S, complete sequence
Blocking peptide available as NCP0167P
COPYRIGHT © 2015-2018 Bioworld Technology, Inc. All rights reserved POLYCLONAL AND MONOCLONAL ANTIBODY CENTER