Product Name :
PDX1 Rabbit monoclonal antibody Background :
The pancreatic duodenal homeobox gene-1 (Pdx1) is a transcription factor that contributes to pancreas development, pancreatic β-cell differentiation, and mature β-cell function. It plays an essential role in the commitment of endoderm to a pancreatic and later β-cell phenotype. In the mature pancreas, Pdx1 expression is more restricted to the pancreatic β-cells, where it promotes the expression of genes important for β-cell functions such as insulin, glucokinase, and Glut2. Mutations of the corresponding Pdx1 gene may be associated with diabetes and cases of pancreatic insufficiency. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
PDX1 Rabbit monoclonal antibody detects endogenous levels of PDX1 protein. Immunogen :
Synthetic peptide, corresponding to Human PDX1. Conjugate :
Unconjugated Modification :
Unmodified

• 
  Western blot (WB) analysis of PDX1 Rabbit monoclonal antibody at 1:500 dilution Lane1:SGC7901 whole cell lysate(30ug) Lane2:HuT78 whole cell lysate(30ug)

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

---

Price/Size :

USD 368/1mg/vial

---

---

Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

---

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

---

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

---

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

---

Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

---