Product Name :
GAPDH polyclonal antibody Background :
Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GAPDH polyclonal antibody detects endogenous levels of GAPDH protein. Immunogen :
Recombinant full length Human GAPDH. Conjugate :
Unconjugated Modification :
Unmodified
GAPDH polyclonal antibody Background :
Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GAPDH polyclonal antibody detects endogenous levels of GAPDH protein. Immunogen :
Recombinant full length Human GAPDH. Conjugate :
Unconjugated Modification :
Unmodified
-
Western blot (WB) analysis of GAPDH pAb at 1:5000/1:10000/1:20000/1:40000 dilution Lane1:L02 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:MG63 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Rat(40ug) Lane7:The Brain tissue lysate of Mouse(40ug)
PMCID: Pubmed No.:
Chromatin Accessibility Dynamics during iPSC Reprogramming
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Chromatin Accessibility Dynamics during iPSC Reprogramming
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Melatonin alleviates adipose inflammation through elevating α‐ketoglutarate and diverting adipose‐derived exosomes to macrophages in mice
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Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells
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Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
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The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation
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miR-29b contributes to multiple types of muscle atrophy
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A proteomic study on liver impairment in rat pups induced by maternal microcystin-LR exposure
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Peri-tumor associated fibroblasts promote intrahepatic metastasis of hepatocellular carcinoma by recruiting cancer stem cells
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Optimized dissociation protocol for isolating human glioma stem cells from tumorspheres via fluorescence-activated cell sorting
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Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells
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Long non-coding RNA LINC00968 acts as oncogene in NSCLC by activating the Wnt signaling pathway
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Hydrogen Sulfide Attenuates Inflammatory Hepcidin by Reducing IL-6 Secretion and Promoting SIRT1-Mediated STAT3 Deacetylation
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Superoxide anions in the paraventricular nucleus mediate cardiac sympathetic afferent reflex in insulin resistance rats
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Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light
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Functional screen analysis reveals miR-3142 as central regulator in chemoresistance and proliferation through activation of the PTEN-AKT pathway in CML
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Histone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition
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Bilirubin neurotoxicity is associated with proteasome inhibition
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Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation
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miRNA-223 upregulated by MYOD inhibits myoblast proliferation by repressing IGF2 and facilitates myoblast differentiation by inhibiting ZEB1
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Exosomal miR-146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin-1β-Primed Mesenchymal Stem Cells Against Sepsis
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S100A8 contributes to postoperative cognitive dysfunction in mice undergoing tibial fracture surgery by activating the TLR4/MyD88 pathway
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Silencing of Wnt10B reduces viability of heptocellular carcinoma HepG2 cells
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Modulation of the pentose phosphate pathway alters phase I metabolism of testosterone and dextromethorphan in HepG2 cells
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UBR2 Enriched in p53 Deficient Mouse Bone Marrow Mesenchymal Stem Cell‐Exosome Promoted Gastric Cancer Progression via Wnt/β‐Catenin Pathway
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Long Noncoding RNA‐1604 Orchestrates Neural Differentiation through the miR‐200c/ZEB Axis
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MicroRNA‐146b, a Sensitive Indicator of Mesenchymal Stem Cell Repair of Acute Renal Injury
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Omentin protects against LPS-induced ARDS through suppressing pulmonary inflammation and promoting endothelial barrier via an Akt/eNOS-dependent mechanism
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Adiponectin reduces ER stress-induced apoptosis through PPAR α transcriptional regulation of ATF2 in mouse adipose
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Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor
PMCID: Pubmed No.:28151478
Ginsenoside Rg5 increases cardiomyocyte resistance to ischemic injury through regulation of mitochondrial hexokinase-II and dynamin-related protein 1
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MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer
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Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathway
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Human urinary kallidinogenase suppresses cerebral inflammation in experimental stroke and downregulates nuclear factor-κB
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miR-106a–mediated Malignant Transformation of Cells Induced by Anti-benzo [a] pyrene-trans-7, 8-diol-9, 10-epoxide.
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miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP
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The proteomic study on cellular responses of the testes of zebrash (Danio rerio) exposed to microcystin-RR
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Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway
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miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes
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Natural Products as a Gold Mine for Selective Matrix Metalloproteinases Inhibitors
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Down regulation of differentiated embryonic chondrocytes 1 (DEC1) is involved in 8-methoxypsoralen-induced apoptosis in HepG2 cells
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Methylated actinomycin D, a novel actinomycin D analog induces apoptosis in HepG2 cells through fas- and mitochondria-mediated pathways†
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Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells
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JNK pathway decreases thyroid hormones via TRH receptor: A novel mechanism for disturbance of thyroid hormone homeostasis by PCB153
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Phycocyanin may suppress d-galactose-induced human lens epithelial cell apoptosis through mitochondrial and unfolded protein response pathways
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Adrenomedullin Attenuates Vascular Calcification in Fructose-induced Insulin Resistance Rats
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Human Umbilical Cord Stem Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Regulating Immunoinflammation and Remyelination
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hSSB1 regulates both the stability and the transcriptional activity of p53
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miR-154 inhibits prostate cancer cell proliferation by targeting CCND2
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Vinexin-β protects against cardiac hypertrophy by blocking the Akt-dependent signalling pathway
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Anti-ABCG2 monoclonal antibody in combination with paclitaxel nanoparticles against cancer stem-like cell activity in multiple myeloma.
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Impact of High Salt Independent of Blood Pressure on PRMT/ADMA/DDAH Pathway in the Aorta of Dahl Salt-Sensitive Rats
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miR-145 inhibits isoproterenol-induced cardiomyocyte hypertrophy by targeting the expression and localization of GATA6.
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Opposite effects of genistein on the regulation of insulin-mediated glucose homeostasis in adipose tissue
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Promotion of Melanoma Cell Invasion and Tumor Metastasis by Microcystin-LR via Phosphatidylinositol 3-Kinase/AKT Pathway.
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Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment
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Inhibition of SIRT1 combined with gemcitabine therapy for pancreatic carcinoma.
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NBPF is a potential DNA-binding transcription factor that is directly regulated by NF-κB
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Expression of Rac-1 related to tumor depth, lymph node metastasis and patient prognosis in esophageal squamous cell carcinoma
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Microvesicle-shuttled miR-130b reduces fat deposition in recipient primary cultured porcine adipocytes by inhibiting PPAR-γ expression
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Indole conjugated silica and magnetic nanoparticles as inhibitors of HIF
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Extracellular polysaccharide from Bacillus sp. strain LBP32 prevents LPS-induced inflammation in RAW 264.7 macrophages by inhibiting NF-κB and MAPKs activation and ROS production
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Cardiac ablation of rheb1 induces impaired heart growth, endoplasmic reticulum-associated apoptosis and heart failure in infant mice.
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Pregnancy-induced physiological hypertrophy protects against cardiac ischemia-reperfusion injury
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Extracellular polysaccharide from Bacillus sp. strain LBP32 prevents LPS-induced inflammation in RAW 264.7 macrophages by inhibiting NF-κB and MAPKs activation and ROS production
PMCID: Pubmed No.:24201081
Molecular Mechanisms of Exopolysaccharide from Aphanothece halaphytica (EPSAH) Induced Apoptosis in HeLa Cells
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An EGFR gene of the Pacific oyster Crassostrea gigas functions in wound healing and promotes cell proliferation
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Snail Contributes to the Maintenance of Stem Cell-Like Phenotype Cells in Human Pancreatic Cancer
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SIRT1 inhibition by sirtinol aggravates brain edema after experimental subarachnoid hemorrhage
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Resveratrol prevents neuronal apoptosis in an early brain injury model
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Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats
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The Epstein-Barr Virus-Encoded MicroRNA MiR-BART9 Promotes Tumor Metastasis by Targeting E-Cadherin in Nasopharyngeal Carcinoma
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Overexpression of BAT3 Alleviates Prion Protein Fragment PrP106‐126‐Induced Neuronal Apoptosis
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Cytohesins/ARNO: The Function in Colorectal Cancer Cells
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Asiaticoside attenuates memory impairment induced by transient cerebral ischemia-reperfusion in mice through anti-inflammatory mechanism
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Catalpol promotes oligodendrocyte survival and oligodendrocyte progenitor differentiation via the Akt signaling pathway in rats with chronic cerebral hypoperfusion.
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Lack of seipin in neurons results in anxiety-and depression-like behaviors via down regulation of PPARγ
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Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling.
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mTOR-targeted therapy: differential perturbation to mitochondrial membrane potential and permeability transition pore plays a role in therapeutic response
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Cytoplasmic Retention of a Nucleocytoplasmic Protein TBC1D3 by Microtubule Network Is Required for Enhanced EGFR Signaling
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Bursopentin (BP5) from chicken bursa of fabricius attenuates the immune function of dendritic cells
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Smurf2 Negatively Modulates RIG-I–dependent Antiviral Response by Targeting VISA/MAVS for Ubiquitination and Degradation
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IQGAP3 Promotes EGFR-ERK Signaling and the Growth and Metastasis of Lung Cancer Cells
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LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/β-catenin signaling pathway in colorectal cancer cells
PMCID: Pubmed No.:25025569
CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.
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MTA1 regulates higher-order chromatin structure and histone H1-chromatin interaction in-vivo.
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Fluoxetine suppresses AMP-activated protein kinase signaling pathway to promote hepatic lipid accumulation in primary mouse hepatocytes
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Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1
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The Transcription Factor FOXA2 Suppresses Gastric Tumorigenesis In Vitro and In Vivo
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A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa heat shock protein HSP90AA1 and its client proteins in cancer cells.
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Reversion of trichostatin A resistance via inhibition of the Wnt signaling pathway in human pancreatic cancer cells
PMCID: Pubmed No.:22213040
Regional Arterial Infusion with Lipoxin A4 Attenuates Experimental Severe Acute Pancreatitis
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Effects of gastrokine‑2 expression on gastric cancer cell apoptosis by activation of extrinsic apoptotic pathways
PMCID: Pubmed No.:25270871
Alpha-lipoic acid upregulates SIRT1-dependent PGC-1α expression and protects mouse brain against focal ischemia. (Application: Rat WB)
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Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers
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Superoxide anions in the paraventricular nucleus mediate cardiac sympathetic afferent reflex in insulin resistance rats. (Application: Rat WB)
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Alternation of adriamycin penetration kinetics in MCF-7 cells from 2D to 3D culture based on P-gp expression through the Chk2/p53/NF-κB pathway
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Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner.
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Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development
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Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium.
PMCID: Pubmed No.:25922268
Respiratory syncytial virus infection upregulates NLRC5 and MHC I expression through RIG-I induction in airway epithelial cells.
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MicroRNA-218 inhibits the proliferation and metastasis of esophageal squamous cell carcinoma cells by targeting BMI1
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The influence of maternal dietary fat on the fatty acid composition and lipid metabolism in the subcutaneous fat of progeny pigs
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The oncogene c-Jun impedes somatic cell reprogramming
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Iptakalim inhibits PDGF-BB-induced Human airway smooth muscle cells proliferation and migration
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Hydrogen sulfide attenuates inflammatory hepcidin by reducing IL-6 secretion and promoting SIRT1-mediated STAT3 deacetylation
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Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction.
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Endoplasmic reticulum ribosome-binding protein 1, RRBP1, promotes progression of colorectal cancer and predicts an unfavourable prognosis.
PMCID: Pubmed No.:26196185
Non-classical MHC IE negatively regulates macrophage activation and Th17 cell development in NOD mice
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Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK
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8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition
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Curcumin alleviated the toxic reaction of Rhizoma Paridis saponins in a 45‐day subchronic toxicological assessment of rats
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Interferon-γ and tumor necrosis factor-α promote the ability of human placenta-derived mesenchymal stromal cells to express programmed death ligand-2 and induce the differentiation of CD4(+)interleukin-10(+) and CD8(+)interleukin-10(+)Treg subsets.
PMCID: Pubmed No.:26432559
Quercetin oppositely regulates insulin‐mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation
PMCID: Pubmed No.:26627467
Corilagin Attenuates Radiation-Induced Brain Injury in Mice
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PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells
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MiR-582-5p/miR-590-5p targeted CREB1/CREB5–NF-κB signaling and caused opioid-induced immunosuppression in human monocytes
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A novel nickel complex works as a proteasomal deubiquitinase inhibitor for cancer therapy
PMCID: Pubmed No.:27086925
MTA1 regulates higher-order chromatin structure and histone H1-chromatin interaction in-vivo.
PMCID: Pubmed No.:25205035
Fluoxetine suppresses AMP-activated protein kinase signaling pathway to promote hepatic lipid accumulation in primary mouse hepatocytes
PMCID: Pubmed No.:25102273
Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1
PMCID: Pubmed No.:25108154
The Transcription Factor FOXA2 Suppresses Gastric Tumorigenesis In Vitro and In Vivo
PMCID: Pubmed No.:25129104
A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa heat shock protein HSP90AA1 and its client proteins in cancer cells.
PMCID: Pubmed No.:25167922
Reversion of trichostatin A resistance via inhibition of the Wnt signaling pathway in human pancreatic cancer cells
PMCID: Pubmed No.:22213040
Regional Arterial Infusion with Lipoxin A4 Attenuates Experimental Severe Acute Pancreatitis
PMCID: Pubmed No.:25265022
Effects of gastrokine‑2 expression on gastric cancer cell apoptosis by activation of extrinsic apoptotic pathways
PMCID: Pubmed No.:25270871
Alpha-lipoic acid upregulates SIRT1-dependent PGC-1α expression and protects mouse brain against focal ischemia. (Application: Rat WB)
PMCID: Pubmed No.:25281876
Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers
PMCID: Pubmed No.:25288727
Superoxide anions in the paraventricular nucleus mediate cardiac sympathetic afferent reflex in insulin resistance rats. (Application: Rat WB)
PMCID: Pubmed No.:25307720
Alternation of adriamycin penetration kinetics in MCF-7 cells from 2D to 3D culture based on P-gp expression through the Chk2/p53/NF-κB pathway
PMCID: Pubmed No.:25478729
Microvesicle-shuttled miR-130b reduces fat deposition in recipient primary cultured porcine adipocytes by inhibiting PPAR-γ expression
PMCID: Pubmed No.:None
Indole conjugated silica and magnetic nanoparticles as inhibitors of HIF
PMCID: Pubmed No.:24184535
Extracellular polysaccharide from Bacillus sp. strain LBP32 prevents LPS-induced inflammation in RAW 264.7 macrophages by inhibiting NF-κB and MAPKs activation and ROS production
PMCID: Pubmed No.:24201081
Curcumin alleviated the toxic reaction of Rhizoma Paridis saponins in a 45‐day subchronic toxicological assessment of rats
PMCID: Pubmed No.:26390842
Interferon-γ and tumor necrosis factor-α promote the ability of human placenta-derived mesenchymal stromal cells to express programmed death ligand-2 and induce the differentiation of CD4(+)interleukin-10(+) and CD8(+)interleukin-10(+)Treg subsets.
PMCID: Pubmed No.:26432559
Quercetin oppositely regulates insulin‐mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation
PMCID: Pubmed No.:26627467
Corilagin Attenuates Radiation-Induced Brain Injury in Mice
PMCID: Pubmed No.:26666668
PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells
PMCID: Pubmed No.:26860588
MiR-582-5p/miR-590-5p targeted CREB1/CREB5–NF-κB signaling and caused opioid-induced immunosuppression in human monocytes
PMCID: Pubmed No.:26978739
A novel nickel complex works as a proteasomal deubiquitinase inhibitor for cancer therapy
PMCID: Pubmed No.:27086925
Cardiac ablation of rheb1 induces impaired heart growth, endoplasmic reticulum-associated apoptosis and heart failure in infant mice.
PMCID: Pubmed No.:24351823
Pregnancy-induced physiological hypertrophy protects against cardiac ischemia-reperfusion injury
PMCID: Pubmed No.:24427343
Extracellular polysaccharide from Bacillus sp. strain LBP32 prevents LPS-induced inflammation in RAW 264.7 macrophages by inhibiting NF-κB and MAPKs activation and ROS production
PMCID: Pubmed No.:24201081
Molecular Mechanisms of Exopolysaccharide from Aphanothece halaphytica (EPSAH) Induced Apoptosis in HeLa Cells
PMCID: Pubmed No.:24466342
An EGFR gene of the Pacific oyster Crassostrea gigas functions in wound healing and promotes cell proliferation
PMCID: Pubmed No.:24469720
Snail Contributes to the Maintenance of Stem Cell-Like Phenotype Cells in Human Pancreatic Cancer
PMCID: Pubmed No.:24489910
SIRT1 inhibition by sirtinol aggravates brain edema after experimental subarachnoid hemorrhage
PMCID: Pubmed No.:24482345
Resveratrol prevents neuronal apoptosis in an early brain injury model
PMCID: Pubmed No.:24602480
Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats
PMCID: Pubmed No.:24587659
The Epstein-Barr Virus-Encoded MicroRNA MiR-BART9 Promotes Tumor Metastasis by Targeting E-Cadherin in Nasopharyngeal Carcinoma
PMCID: Pubmed No.:24586173
Overexpression of BAT3 Alleviates Prion Protein Fragment PrP106‐126‐Induced Neuronal Apoptosis
PMCID: Pubmed No.:24629137
Cytohesins/ARNO: The Function in Colorectal Cancer Cells
PMCID: Pubmed No.:24618737
Asiaticoside attenuates memory impairment induced by transient cerebral ischemia-reperfusion in mice through anti-inflammatory mechanism
PMCID: Pubmed No.:24631487
Catalpol promotes oligodendrocyte survival and oligodendrocyte progenitor differentiation via the Akt signaling pathway in rats with chronic cerebral hypoperfusion.
PMCID: Pubmed No.:24632336
Lack of seipin in neurons results in anxiety-and depression-like behaviors via down regulation of PPARγ
PMCID: Pubmed No.:24651066
Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling.
PMCID: Pubmed No.:24686082
mTOR-targeted therapy: differential perturbation to mitochondrial membrane potential and permeability transition pore plays a role in therapeutic response
PMCID: Pubmed No.:24704448
Cytoplasmic Retention of a Nucleocytoplasmic Protein TBC1D3 by Microtubule Network Is Required for Enhanced EGFR Signaling
PMCID: Pubmed No.:24714105
Bursopentin (BP5) from chicken bursa of fabricius attenuates the immune function of dendritic cells
PMCID: Pubmed No.:24710706
Smurf2 Negatively Modulates RIG-I–dependent Antiviral Response by Targeting VISA/MAVS for Ubiquitination and Degradation
PMCID: Pubmed No.:24729608
Hydrogen Sulfide Mitigates Myocardial Infarction via Promotion of Mitochondrial Biogenesis-Dependent M2 Polarization of Macrophages
PMCID: Pubmed No.:27296720
Inhibition of Mitochondrial Fission and NOX2 Expression Prevent NLRP3 Inflammasome Activation in the Endothelium: The Role of Corosolic Acid Action in the Amelioration of Endothelial Dysfunction
PMCID: Pubmed No.:26869350
The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells
PMCID: Pubmed No.:27060717
Helicobacter pylori inhibits the cleavage of TRAF1 via a CagA-dependent mechanism
PMCID: Pubmed No.:28082808
Activation of PPARγ Ameliorates Spatial Cognitive Deficits through Restoring Expression of AMPA Receptors in Seipin Knock-Out Mice
PMCID: Pubmed No.:26818512
Soluble receptor for advanced glycation end-products protects against ischemia/reperfusion-induced myocardial apoptosis via regulating the ubiquitin proteasome system
PMCID: Pubmed No.:26878774
Wogonoside inhibits invasion and migration through suppressing TRAF2/4 expression in breast cancer
PMCID: Pubmed No.:28774312
Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development
PMCID: Pubmed No.:25670795
Persistent mitoKATP Activation Is Involved in the Isoflurane-induced Cytotoxicity
PMCID: Pubmed No.:26803495
The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1
PMCID: Pubmed No.:26808085
Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner
PMCID: Pubmed No.:26054569
miR‐1470 mediates lapatinib induced p27 upregulation by targeting c‐jun
PMCID: Pubmed No.:25545366
Beneficial effects of renal denervation on cardiac angiogenesis in rats with prolonged pressure overload
PMCID: Pubmed No.:27575955
Adipose afferent reflex response to insulin is mediated by melanocortin 4 type receptors in the paraventricular nucleus in insulin resistance rats
PMCID: Pubmed No.:25846948
Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis
PMCID: Pubmed No.:28491151
Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue
PMCID: Pubmed No.:27746687
Cutting Edge: TRAF6 Mediates TLR/IL-1R Signaling–Induced Nontranscriptional Priming of the NLRP3 Inflammasome
PMCID: Pubmed No.:28739881
Endoplasmic reticulum ribosome-binding protein 1, RRBP1, promotes progression of colorectal cancer and predicts an unfavourable prognosis
PMCID: Pubmed No.:26196185
Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy
PMCID: Pubmed No.:29296531
Ulinastatin protects brain against cerebral ischemia/reperfusion injury through inhibiting MMP-9 and alleviating loss of ZO-1 and occludin proteins in mice
PMCID: Pubmed No.:29291404
Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure
PMCID: Pubmed No.:25851780
d‐Chiro inositol ameliorates endothelial dysfunction via inhibition of oxidative stress and mitochondrial fission
PMCID: Pubmed No.:28087886
MiR-582-5p/miR-590-5p targeted CREB1/CREB5–NF-κB signaling and caused opioid-induced immunosuppression in human monocytes
PMCID: Pubmed No.:26978739
eEF2K promotes progression and radioresistance of esophageal squamous cell carcinoma
PMCID: Pubmed No.:28431753
Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease
PMCID: Pubmed No.:28381600
The role of the miR-31/FIH1 pathway in TGF-β-induced liver fibrosis
PMCID: Pubmed No.:25728779
MicroRNA-132 promotes estradiol synthesis in ovarian granulosa cells via translational repression of Nurr1
PMCID: Pubmed No.:26282993
The influence of maternal dietary fat on the fatty acid composition and lipid metabolism in the subcutaneous fat of progeny pigs
PMCID: Pubmed No.:26047981
2β, 3β, 23-trihydroxy-urs-12-ene-28-olic acid (TUA) isolated from Actinidia chinensis Radix inhibits NCI-H460 cell proliferation by decreasing NF-κB expression
PMCID: Pubmed No.:26134000
Malat1 regulates serum response factor through miR-133 as a competing endogenous RNA in myogenesis
PMCID: Pubmed No.:25868726
CSF-1R regulates non-small cell lung cancer cells dissemination through Wnt3a signaling
PMCID: Pubmed No.:29218239
Succinate/NLRP3 Inflammasome Induces Synovial Fibroblast Activation: Therapeutical Effects of Clematichinenoside AR on Arthritis
PMCID: Pubmed No.:28003810
MnTBAP Therapy Attenuates Renal Fibrosis in Mice with 5/6 Nephrectomy
PMCID: Pubmed No.:26989454
HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation
PMCID: Pubmed No.:27110324
An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases
PMCID: Pubmed No.:26456587
Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction
PMCID: Pubmed No.:26196303
Low Dose of Bisphenol A Activates NF-κB/IL-6 Signals to Increase Malignancy of Neuroblastoma Cells
PMCID: Pubmed No.:27866306
Inhibition of Autophagy is Involved in the Protective Effects of Ginsenoside Rb1 on Spinal Cord Injury
PMCID: Pubmed No.:28762191
Fungal metabolite myriocin promotes human herpes simplex virus-2 infection
PMCID: Pubmed No.:25447452
Dermokine contributes to epithelial–mesenchymal transition through increased activation of signal transducer and activator of transcription 3 in pancreatic cancer
PMCID: Pubmed No.:28795470
Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy
PMCID: Pubmed No.:27381943
Alternation of adriamycin penetration kinetics in MCF-7 cells from 2D to 3D culture based on P-gp expression through the Chk2/p53/NF-κB pathway
PMCID: Pubmed No.:25478729
Surface topography of hydroxyapatite promotes osteogenic differentiation of human bone marrow mesenchymal stem cells
PMCID: Pubmed No.:26706505
Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons
PMCID: Pubmed No.:26363976
Casein Kinase II Controls TBK1/IRF3 Activation in IFN Response against Viral Infection
PMCID: Pubmed No.:25810395
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids attenuates K/BxN serum-transfer arthritis in fat-1 mice
PMCID: Pubmed No.:25910895
EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway
PMCID: Pubmed No.:26539255
Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control
PMCID: Pubmed No.:29359009
Tris (2-chloroethyl) phosphate induces senescence-like phenotype of hepatocytes via the p21Waf1/Cip1-Rb pathway in a p53-independent manner
PMCID: Pubmed No.:28886428
The saponin DT-13 Attenuates Tumor Necrosis Factor-α-induced Vascular Inflammation Associated with Src/NF-кB/MAPK Pathway Modulation
PMCID: Pubmed No.:26157351
A dioxidovanadium (V) complex of NNO-donor Schiff base as a selective inhibitor of protein tyrosine phosphatase 1B: Synthesis, characterization, and biological activities
PMCID: Pubmed No.:28199951
Xanthatin anti-tumor cytotoxicity is mediated via glycogen synthase kinase-3β and β-catenin
PMCID: Pubmed No.:27321043
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway
PMCID: Pubmed No.:28038913
Microcystin-LR promotes migration and invasion of colorectal cancer through matrix metalloproteinase-13 up-regulation
PMCID: Pubmed No.:25789966
Lactoferrin promotes MC3T3-E1 osteoblast cells proliferation via MAPK signaling pathways
PMCID: Pubmed No.:28863893
Establishment of MAGEC2‐knockout cells and functional investigation of MAGEC2 in tumor cells
PMCID: Pubmed No.:27636589
Inducible ATF3–NFAT axis aggravates podocyte injury
PMCID: Pubmed No.:29038896
Therapeutic inhibition of SGK1 suppresses colorectal cancer
PMCID: Pubmed No.:29170478
Berberine ameliorates collagen‐induced arthritis in rats by suppressing Th17 cell responses via inducing cortistatin in the gut
PMCID: Pubmed No.:28636167
MiR-106b-mediated Mfn2 suppression is critical for PKM2 induced mitochondrial fusion
PMCID: Pubmed No.:27822413
Maresin 1 Mitigates High Glucose-Induced Mouse Glomerular Mesangial Cell Injury by Inhibiting Inflammation and Fibrosis
PMCID: Pubmed No.:28182085
Upregulation of mitogen-inducible gene 6 triggers antitumor effect and attenuates progesterone resistance in endometrial carcinoma cells
PMCID: Pubmed No.:26450625
Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice
PMCID: Pubmed No.:25956868
Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice
PMCID: Pubmed No.:25846502
Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and prevents insulin resistance in the endothelium
PMCID: Pubmed No.:30666402
PAC1R agonist maxadilan enhances hADSC viability and neural differentiation potential
PMCID: Pubmed No.:26798992
Sulindac has strong antifibrotic effects by suppressing STAT3‐related miR‐21
PMCID: Pubmed No.:25704671
Quercetin oppositely regulates insulin‐mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation
PMCID: Pubmed No.:26627467
Alteration of Cholinergic Anti‐Inflammatory Pathway in Rat With Ischemic Cardiomyopathy–Modified Electrophysiological Function of Heart
PMCID: Pubmed No.:28928157
The Pivotal Role of Ca2+ Homeostasis in PBDE-47-Induced Neuronal Apoptosis
PMCID: Pubmed No.:26676572
Corilagin Attenuates Radiation-Induced Brain Injury in Mice
PMCID: Pubmed No.:26666668
Single injection of a novel nerve growth factor coacervate improves structural and functional regeneration after sciatic nerve injury in adult rats
PMCID: Pubmed No.:27983992
MiR-451 suppresses proliferation, migration and promotes apoptosis of the human osteosarcoma by targeting macrophage migration inhibitory factor
PMCID: Pubmed No.:28086136
mPGES-1-derived prostaglandin E2 stimulates Stat3 to promote podocyte apoptosis
PMCID: Pubmed No.:28879567
A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25–35-impaired mouse cognitive function
PMCID: Pubmed No.:26349994
Alpha‐Lipoic Acid Promotes Osteoblastic Formation in H2O2‐Treated MC3T3‐E1 Cells and Prevents Bone Loss in Ovariectomized Rats
PMCID: Pubmed No.:25655087
Respiratory Syncytial Virus Infection Upregulates NLRC5 and Major Histocompatibility Complex Class I Expression through RIG-I Induction in Airway Epithelial Cells
PMCID: Pubmed No.:25972545
P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions
PMCID: Pubmed No.:26136569
Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus
PMCID: Pubmed No.:27660267
Activation of Wnt/β‐catenin signalling is required for TGF‐β/Smad2/3 signalling during myofibroblast proliferation
PMCID: Pubmed No.:28244647
Cardiac cell proliferation is not necessary for exercise‐induced cardiac growth but required for its protection against ischaemia/reperfusion injury
PMCID: Pubmed No.:28304151
Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice
PMCID: Pubmed No.:27317762
Targeted inhibition of HDAC8 increases the doxorubicin sensitivity of neuroblastoma cells via up regulation of miR-137
PMCID: Pubmed No.:28223126
Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain
PMCID: Pubmed No.:28669900
Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice
PMCID: Pubmed No.:28925407
Phosphatidic acid induces decidualization by stimulating Akt‐PP2A binding in human endometrial stromal cells
PMCID: Pubmed No.:27696687
FSTL1 as a Potential Mediator of Exercise-Induced Cardioprotection in Post-Myocardial Infarction Rats
PMCID: Pubmed No.:27561749
Renal Denervation Findings on Cardiac and Renal Fibrosis in Rats with Isoproterenol Induced Cardiomyopathy
PMCID: Pubmed No.:26689945
A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family
PMCID: Pubmed No.:25374051
MiR-200c regulates tumor growth and chemosensitivity to cisplatin in osteosarcoma by targeting AKT2
PMCID: Pubmed No.:29051585
microRNA-124 targets glucocorticoid receptor and is involved in depression-like behaviors
PMCID: Pubmed No.:28764913
Geniposide attenuates ANIT-induced cholestasis through regulation of transporters and enzymes involved in bile acids homeostasis in rats
PMCID: Pubmed No.:27988401
αMSH promotes preadipocyte proliferation by alleviating ER stress-induced leptin resistance and by activating Notch1 signal in mice
PMCID: Pubmed No.:27717825
Mangiferin protects mitochondrial function by preserving mitochondrial hexokinase-II in vessel endothelial cells
PMCID: Pubmed No.:28478227
Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1
PMCID: Pubmed No.:28736181
The effects of autophagy on vascular endothelial cells induced by airborne PM2.5
PMCID: Pubmed No.:29628085
Corosolic acid inhibits adipose tissue inflammation and ameliorates insulin resistance via AMPK activation in high-fat fed mice
PMCID: Pubmed No.:26926180
Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms
PMCID: Pubmed No.:26960947
Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage
PMCID: Pubmed No.:28935668
iTRAQ protein profile analysis of neuroblastoma (NA) cells infected with the rabies viruses rHep-Flury and Hep-dG
PMCID: Pubmed No.:26217322
The Combination of Three Components Derived from Sheng MaiSan Protects Myocardial Ischemic Diseases and Inhibits Oxidative Stress via Modulating MAPKs and JAK2-STAT3 Signaling Pathways Based on Bioinformatics Approach
PMCID: Pubmed No.:28197101
Daily Suction Provided by External Volume Expansion Inducing Regeneration of Grafted Fat in a Murine Model
PMCID: Pubmed No.:28121866
Lipoxin A 4 activates alveolar epithelial sodium channel gamma via the microRNA-21/PTEN/AKT pathway in lipopolysaccharide-induced inflammatory lung injury
PMCID: Pubmed No.:26302186
Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies
PMCID: Pubmed No.:26978516
Evaluation and Treatment of Endoplasmic Reticulum (ER) Stress in Right Ventricular Dysfunction during Monocrotaline-Induced Rat Pulmonary Arterial Hypertension
PMCID: Pubmed No.:27844183
Partial inhibition of activin receptor-like kinase 4 attenuates pressure overload-induced cardiac fibrosis and improves cardiac function
PMCID: Pubmed No.:27379535
Comparative proteomic analysis of the effects of high-concentrate diet on the hepatic metabolism and inflammatory response in lactating dairy goats
PMCID: Pubmed No.:26855776
The important role of the receptor for activated C kinase 1 (RACK1) in nasopharyngeal carcinoma progression
PMCID: Pubmed No.:27170279
Curcumin alleviated the toxic reaction of Rhizoma Paridis saponins in a 45-day subchronic toxicological assessment of rats
PMCID: Pubmed No.:26390842
Enhanced HOXA10 sumoylation inhibits embryo implantation in women with recurrent implantation failure
PMCID: Pubmed No.:29018572
Elimination of GPR146‐mediated antiviral function through IRF3/HES1‐signalling pathway
PMCID: Pubmed No.:28464285
Interleukin‐17 regulates the expressions of RANKL and OPG in human periodontal ligament cells via TRAF6/TBK1‐JNK/NF‐κB pathways
PMCID: Pubmed No.:25263088
Three novel missense mutations in the filamin B gene are associated with isolated congenital talipes equinovarus
PMCID: Pubmed No.:27395407
The chromatin remodeler Chd4 maintains embryonic stem cell identity by controlling pluripotency- and differentiation-associated genes
PMCID: Pubmed No.:28298436
Aqueous extract of pomegranate seed attenuates glucocorticoid-induced bone loss and hypercalciuria in mice: A comparative study with alendronate
PMCID: Pubmed No.:27278225
Reg3α Overexpression Protects Pancreatic β Cells from Cytokine-Induced Damage and Improves Islet Transplant Outcome
PMCID: Pubmed No.:25826674
Aspirin Inhibits LPS-Induced Expression of PI3K/Akt, ERK, NF-κB, CX3CL1, and MMPs in Human Bronchial Epithelial Cells
PMCID: Pubmed No.:26635114
Triterpenoids‐Enriched Extract from the Aerial Parts of Salvia miltiorrhiza Regulates Macrophage Polarization and Ameliorates Insulin Resistance in High‐Fat Fed Mice
PMCID: Pubmed No.:27714922
Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice
PMCID: Pubmed No.:29174741
Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxidative Injury through ERK1/2 Signaling Pathway
PMCID: Pubmed No.:27994507
Dual Delivery of NGF and bFGF Coacervater Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Schwann Cells Apoptosis
PMCID: Pubmed No.:28539836
Salvianolic acids enhance cerebral angiogenesis and neurological recovery by activating JAK2/STAT3 signaling pathway after ischemic stroke in mice
PMCID: Pubmed No.:28771727
Effects of microRNA-29a on retinopathy of prematurity by targeting AGT in a mouse model
PMCID: Pubmed No.:28337307
Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3
PMCID: Pubmed No.:26818531
Effect of bovine lactoferrin and human lactoferrin on the proliferative activity of the osteoblast cell line MC3T3-E1 in vitro
PMCID: Pubmed No.:29290425
Demethyleneberberine, a Natural Mitochondria-Targeted Antioxidant, Inhibits Mitochondrial Dysfunction, Oxidative Stress, and Steatosis in Alcoholic Liver Disease Mouse Model
PMCID: Pubmed No.:25362106
The enhanced atorvastatin hepatotoxicity in diabetic rats was partly attributed to the upregulated hepatic Cyp3a and SLCO1B1
PMCID: Pubmed No.:27624558
Effects of chronic noise on glucose metabolism and gut microbiota–host inflammatory homeostasis in rats
PMCID: Pubmed No.:27811997
MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway
PMCID: Pubmed No.:28165066
Identification of Novel MAGE-G1-Interacting Partners in Retinoic Acid-Induced P19 Neuronal Differentiation Using SILAC-Based Proteomics
PMCID: Pubmed No.:28374796
The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways
PMCID: Pubmed No.:28611356
PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells
PMCID: Pubmed No.:26860588
The Role of Na+/Ca2+ Exchanger 1 in Maintaining Ductus Arteriosus Patency
PMCID: Pubmed No.:28852106
HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism
PMCID: Pubmed No.:27644317
Prophylaxis of Diallyl Disulfide on Skin Carcinogenic Model via p21-dependent Nrf2 stabilization
PMCID: Pubmed No.:27759091
α-MSH and Foxc2 promote fatty acid oxidation through C/EBPβ negative transcription in mice adipose tissue
PMCID: Pubmed No.:27819350
Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3
PMCID: Pubmed No.:28484278
Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia
PMCID: Pubmed No.:28500304
Effects of dietary methionine on breast muscle growth, myogenic gene expression and IGF-I signaling in fast- and slow-growing broilers
PMCID: Pubmed No.:28507342
Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity
PMCID: Pubmed No.:28588300
Oncolytic measles virus enhances antitumour responses of adoptive CD8 + NKG2D + cells in hepatocellular carcinoma treatment
PMCID: Pubmed No.:28701757
Galangin attenuates airway remodelling by inhibiting TGF-β1-mediated ROS generation and MAPK/Akt phosphorylation in asthma
PMCID: Pubmed No.:26156213
Remarkable plasticity of Na + , K + -ATPase, Ca 2+ -ATPase and SERCA contributes to muscle disuse atrophy resistance in hibernating Daurian ground squirrels
PMCID: Pubmed No.:28874726
Detrimental effect of Hypoxia-inducible factor-1α-induced autophagy on multiterritory perforator flap survival in rats
PMCID: Pubmed No.:28924179
Non-classical MHC I-E negatively regulates macrophage activation and Th17 cell development in NOD mice
PMCID: Pubmed No.:26251280
FOXA2 alleviates CCl 4 -induced liver fibrosis by protecting hepatocytes in mice
PMCID: Pubmed No.:15532 (2017)
MiR-30e inhibits tumor growth and chemoresistance via targeting IRS1 in Breast Cancer
PMCID: Pubmed No.:29162879
RNA Interference Silencing of Glycogen Synthase Kinase 3β Inhibites Tau Phosphorylation in Mice with Alzheimer Disease
PMCID: Pubmed No.:27255602
NGF Attenuates High Glucose-Induced ER Stress, Preventing Schwann Cell Apoptosis by Activating the PI3K/Akt/GSK3β and ERK1/2 Pathways
PMCID: Pubmed No.:28762104
Esculentoside A exerts anti-inflammatory activity in microglial cells
PMCID: Pubmed No.:28843178
Autophagy regulates intracerebral hemorrhage induced neural damage via apoptosis and NF-κB pathway
PMCID: Pubmed No.:26964766
FKBP5 and specific microRNAs via glucocorticoid receptor in the basolateral amygdala involved in the susceptibility to depressive disorder in early adolescent stressed rats
PMCID: Pubmed No.:28826069
Cripto-1 promotes epithelial-mesenchymal transition in prostate cancer via Wnt/β-catenin signaling
PMCID: Pubmed No.:28098905
Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction
PMCID: Pubmed No.:26074971
Benzo[a]pyrene promotes gastric cancer cell proliferation and metastasis likely through the Aryl hydrocarbon receptor and ERK-dependent induction of MMP9 and c-myc
PMCID: Pubmed No.:27601158
Prognostic value of pigment epithelium-derived factor for neoadjuvant radiation therapy in patients with locally advanced rectal carcinoma
PMCID: Pubmed No.:27431441
MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer
PMCID: Pubmed No.:26983891
The tumor suppressor miR-124 inhibits cell proliferation by targeting STAT3 and functions as a prognostic marker for postoperative NSCLC patients
PMCID: Pubmed No.:25531908
Effects of macrophage migration inhibitory factor on cardiac reperfusion injury in mice with depression induced by constant-darkness
PMCID: Pubmed No.:29331700
Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice
PMCID: Pubmed No.:26527380
Iron Together with Lipid Downregulates Protein Levels of Ceruloplasmin in Macrophages Associated with Rapid Foam Cell Formation
PMCID: Pubmed No.:27040361
Different Angiogenic Potentials of Mesenchymal Stem Cells Derived from Umbilical Artery, Umbilical Vein, and Wharton’s Jelly
PMCID: Pubmed No.:28874910
Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance
PMCID: Pubmed No.:28261091
Oroxyloside A Overcomes Bone Marrow Microenvironment-Mediated Chronic Myelogenous Leukemia Resistance to Imatinib via Suppressing Hedgehog Pathway
PMCID: Pubmed No.:28848440
Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes
PMCID: Pubmed No.:29234281
Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF‐1α synthesis, and decreases breast cancer metastasis
PMCID: Pubmed No.:28574600
Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK
PMCID: Pubmed No.:26277096
Human Umbilical Cord Mesenchymal Stem Cells Protect Against SCA3 by Modulating the Level of 70 kD Heat Shock Protein
PMCID: Pubmed No.:28667374
Role of 5‐HT1A receptor in insular cortex mediating stress – induced visceral sensory dysfunction
PMCID: Pubmed No.:26969829
Hypoxia-induced and HIF1α-VEGF-mediated tight junction dysfunction in choriocarcinoma cells: Implications for preeclampsia
PMCID: Pubmed No.:29223764
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis
PMCID: Pubmed No.:28689917
Effects of Curcumin on Tobacco Smoke‐induced Hepatic MAPK Pathway Activation and Epithelial–Mesenchymal Transition In Vivo
PMCID: Pubmed No.:28585748
Curcumin Suppresses MAPK Pathways to Reverse Tobacco Smoke‐induced Gastric Epithelial–Mesenchymal Transition in Mice
PMCID: Pubmed No.:26074474
Cigarette smoke extract induces epithelial–mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway
PMCID: Pubmed No.:28012925
Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway
PMCID: Pubmed No.:29136772
Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells
PMCID: Pubmed No.:29793316
Activation of Epac alleviates inflammation and vascular leakage in LPS-induced acute murine lung injury
PMCID: Pubmed No.:29174852
Roles of Pannexin-1 Channels in Inflammatory Response through the TLRs/NF-Kappa B Signaling Pathway Following Experimental Subarachnoid Hemorrhage in Rats
PMCID: Pubmed No.:28634441
LPS-induced CXCR4-dependent migratory properties and a mesenchymal-like phenotype of colorectal cancer cells
PMCID: Pubmed No.:26745593
Metformin and resveratrol inhibit Drp1-mediated mitochondrial fission and prevent ER stress-associated NLRP3 inflammasome activation in the adipose tissue of diabetic mice
PMCID: Pubmed No.:27276511
Esculentoside A suppresses lipopolysaccharide-induced pro-inflammatory molecule production partially by casein kinase 2
PMCID: Pubmed No.:28027904
YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-κB and ROCK1/MLC signaling pathways
PMCID: Pubmed No.:26915982
Huangkui capsule attenuates renal fibrosis in diabetic nephropathy rats through regulating oxidative stress and p38MAPK/Akt pathways, compared to α-lipoic acid
PMCID: Pubmed No.:26226437
D-chiro-inositol enriched Fagopyrum tataricum (L.) Gaench extract alleviates mitochondrial malfunction and inhibits ER stress/JNK associated inflammation in the endothelium
PMCID: Pubmed No.:29225119
Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer’s disease-like tau hyperphosphorylation
PMCID: Pubmed No.:29228900
Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells
PMCID: Pubmed No.:27239113
Diosmetin prevents TGF-β1-induced epithelial-mesenchymal transition via ROS/MAPK signaling pathways
PMCID: Pubmed No.:27101925
Interval exercise training increases LIF expression and prevents myocardial infarction-induced skeletal muscle atrophy in rats
PMCID: Pubmed No.:29223542
Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF‐9/MAPK/Smad pathway
PMCID: Pubmed No.:28346732
miR-451 inhibits cell growth, migration and angiogenesis in human osteosarcoma via down-regulating IL 6R
PMCID: Pubmed No.:27908732
Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress
PMCID: Pubmed No.:26970305
The NLRP3 inflammasome is dispensable for ER stress-induced pancreatic β-cell damage in Akita mice
PMCID: Pubmed No.:26361146
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission
PMCID: Pubmed No.:27960279
Curcumin reverses benzidine-induced epithelial-mesenchymal transition via suppression of ERK5/AP-1 in SV-40 immortalized human urothelial cells
PMCID: Pubmed No.:28259934
Restoration of KLF4 Inhibits Invasion and Metastases of Lung Adenocarcinoma through Suppressing MMP2
PMCID: Pubmed No.:29151932
High-Mobility Group Box 1 Mediates Epithelial-to-Mesenchymal Transition in Pulmonary Fibrosis Involving Transforming Growth Factor-β1/Smad2/3 Signaling
PMCID: Pubmed No.:26126535
Persistent Exposure to Porphyromonas gingivalis Promotes Proliferative and Invasion Capabilities, and Tumorigenic Properties of Human Immortalized Oral Epithelial Cells
PMCID: Pubmed No.:28286742
PSD-93 Attenuates Amyloid-β-Mediated Cognitive Dysfunction by Promoting the Catabolism of Amyloid-β
PMCID: Pubmed No.:28697571
Salvia miltiorrhiza Lipophilic Fraction Attenuates Oxidative Stress in Diabetic Nephropathy through Activation of Nuclear Factor Erythroid 2-Related Factor 2
PMCID: Pubmed No.:28946766
Curcumin attenuates BPA-induced insulin resistance in HepG2 cells through suppression of JNK/p38 pathways
PMCID: Pubmed No.:28300666
BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro
PMCID: Pubmed No.:26024915
Autophagy can alleviate severe burn-induced damage to the intestinal tract in mice
PMCID: Pubmed No.:28624177
Urocortin Attenuates TGFβ1‐Induced Snail1 and Slug Expressions: Inhibitory Role of Smad7 in Smad2/3 Signaling in Breast Cancer Cells
PMCID: Pubmed No.:26138318
The effect of tetrandrine combined with cisplatin on proliferation and apoptosis of A549/DDP cells and A549 cells
PMCID: Pubmed No.:28360820
Differential drug resistance acquisition to doxorubicin and paclitaxel in breast cancer cells
PMCID: Pubmed No.:25550688
miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1
PMCID: Pubmed No.:28260112
Asporin participates in gastric cancer cell growth and migration by influencing EGF receptor signaling
PMCID: Pubmed No.:25673058
Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4
PMCID: Pubmed No.:29048629
Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium
PMCID: Pubmed No.:25922268
The anti-tumour activity of rLj-RGD4, an RGD toxin protein from Lampetra japonica, on human laryngeal squamous carcinoma Hep-2 cells in nude mice
PMCID: Pubmed No.:26549486
Oroxylin A reverses the drug resistance of chronic myelogenous leukemia cells to imatinib through CXCL12/CXCR7 axis in bone marrow microenvironment
PMCID: Pubmed No.:27533597
Functional role and mechanism of lncRNA LOC728228 in malignant 16HBE cells transformed by anti‐benzopyrene‐trans‐7,8‐dihydrodiol‐9,10‐epoxide
PMCID: Pubmed No.:25820656
miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation
PMCID: Pubmed No.:28844858
Phosphorylated heat shock protein 27 promotes lipid clearance in hepatic cells through interacting with STAT3 and activating autophagy
PMCID: Pubmed No.:27185187
FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma
PMCID: Pubmed No.:28559972
Silencing of advanced glycosylation and glycosylation and product-specific receptor (RAGE) inhibits the metastasis and growth of non-small cell lung cancer
PMCID: Pubmed No.:28670367
Characterization of aromatase expression in the spinal cord of an animal model of familial ALS
PMCID: Pubmed No.:28583855
Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats
PMCID: Pubmed No.:25839444
Role of microRNA-29a in the development of diabetic retinopathy by targeting AGT gene in a rat model
PMCID: Pubmed No.:28189547
Treatment with NAD+ inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice
PMCID: Pubmed No.:27500459
Ampelopsin attenuates lipopolysaccharide-induced inflammatory response through the inhibition of the NF-κB and JAK2/STAT3 signaling pathways in microglia
PMCID: Pubmed No.:27998743
The correlation between inflammatory injury induced by LPS and RAS in EpH4-Ev cells
PMCID: Pubmed No.:28249221
Resokaempferol-mediated anti-inflammatory effects on activated macrophages via the inhibition of JAK2/STAT3, NF-κB and JNK/p38 MAPK signaling pathways
PMCID: Pubmed No.:27261558
Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide
PMCID: Pubmed No.:27289299
Induction of forkhead box M1 (FoxM1) by EGF through ERK signaling pathway promotes trophoblast cell invasion
PMCID: Pubmed No.:26022336
Mechanism-Based Inhibitory and Peroxisome Proliferator-Activated Receptor α–Dependent Modulating Effects of Silybin on Principal Hepatic Drug-Metabolizing Enzymes
PMCID: Pubmed No.:25587127
Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity
PMCID: Pubmed No.:27832326
Assessment of mouse cognitive and anxiety-like behaviors and hippocampal inflammation following a repeated and intermittent paradoxical sleep deprivation procedure
PMCID: Pubmed No.:28043900
A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells
PMCID: Pubmed No.:28038917
Iptakalim inhibits PDGF-BB-induced human airway smooth muscle cells proliferation and migration
PMCID: Pubmed No.:26160451
DDAH1-V3 transcript might act as miR-21 sponge to maintain balance of DDAH1-V1 in cultured HUVECs
PMCID: Pubmed No.:27663503
Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells
PMCID: Pubmed No.:26204324
Glutathione-s-transferase A 4 (GSTA4) suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting AKT pathway
PMCID: Pubmed No.:28337261
Interleukin-25 enhances the capacity of mesenchymal stem cells to induce intestinal epithelial cell regeneration
PMCID: Pubmed No.:29312486
Ameliorating effects of 1,8-cineole on LPS-induced human umbilical vein endothelial cell injury by suppressing NF-κB signaling in vitro
PMCID: Pubmed No.:27455900
Inhibition of lipolysis by ilexgenin A via AMPK activation contributes to the prevention of hepatic insulin resistance
PMCID: Pubmed No.:28739087
Hinokitiol copper complex inhibits proteasomal deubiquitination and induces paraptosis-like cell death in human cancer cells
PMCID: Pubmed No.:28887042
Caruifolin D from artemisia absinthium L. inhibits neuroinflammation via reactive oxygen species-dependent c-jun N-terminal kinase and protein kinase c/NF-κB signaling pathways
PMCID: Pubmed No.:26455476
Inhibition of thioredoxin-1 with siRNA exacerbates apoptosis by activating the ASK1-JNK/p38 pathway in brain of a stroke model rats
PMCID: Pubmed No.:25541364
LRG1 suppresses the migration and invasion of hepatocellular carcinoma cells
PMCID: Pubmed No.:25814288
Role of Autophagy in Angiogenesis Induced by a High-Glucose Condition in RF/6A Cells
PMCID: Pubmed No.:28253511
Paeonol inhibits B16F10 melanoma metastasis In vitro and In Vivo via disrupting proinflammatory cytokines‐mediated NF‐κB and STAT3 pathways
PMCID: Pubmed No.:26452780
mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines
PMCID: Pubmed No.:26122641
Changes in milk performance and hepatic metabolism in mid-lactating dairy goats after being fed a high concentrate diet for 10 weeks
PMCID: Pubmed No.:27506262
IL-25 Promotes Th2 Immunity Responses in Asthmatic Mice via Nuocytes Activation
PMCID: Pubmed No.:27617447
The Effects of Auricular Electro-Acupuncture on Ameliorating the Dysfunction of Interstitial Cells of Cajal Networks and nNOSmRNA Expression in Antrum of STZ-Induced Diabetic Rats
PMCID: Pubmed No.:27930657
Expression of heat shock protein 70 in transport-stressed broiler pectoralis major muscle and its relationship with meat quality
PMCID: Pubmed No.:28077200
A Novel Missense Mutation of GATA4 in a Chinese Family with Congenital Heart Disease
PMCID: Pubmed No.:27391137
Therapeutic Effects of Bupleurum Polysaccharides in Streptozotocin Induced Diabetic Mice
PMCID: Pubmed No.:26176625
Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells
PMCID: Pubmed No.:26382838
Protective effects of paeonol on inflammatory response in IL-1β-induced human fibroblast-like synoviocytes and rheumatoid arthritis progression via modulating NF-κB pathway
PMCID: Pubmed No.:28799079
Increased Krüppel-like factor 12 in recurrent implantation failure impairs endometrial decidualization by repressing Nur77 expression
PMCID: Pubmed No.:28359310
Krüppel-like factor 12 is a novel negative regulator of forkhead box O1 expression: a potential role in impaired decidualization
PMCID: Pubmed No.:26223982
NEB-related core-rod myopathy with distinct clinical and pathological features
PMCID: Pubmed No.:26562614
Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway
PMCID: Pubmed No.:26316699
Interaction Between Gastric Carcinoma Cells and Neural Cells Promotes Perineural Invasion by a Pathway Involving VCAM1
PMCID: Pubmed No.:26108418
Naringin prevents carbon tetrachloride-induced acute liver injury in mice
PMCID: Pubmed No.:36559593
miR-134 Functions as a Tumor Suppressor in Cell Proliferation and Epithelial-to-Mesenchymal Transition by Targeting KRAS in Renal Cell Carcinoma Cells
PMCID: Pubmed No.:25811077
Heparanase Contributes To Trans-Endothelial Migration of Hepatocellular Carcinoma Cells
PMCID: Pubmed No.:29158804
Curcumin inhibits placental inflammation to ameliorate LPS-induced adverse pregnancy outcomes in mice via upregulation of phosphorylated Akt
PMCID: Pubmed No.:27817102
Insights into anticancer activity and mechanism of action of a ruthenium(II) complex in human esophageal squamous carcinoma EC109 cells
PMCID: Pubmed No.:27262377
MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells
PMCID: Pubmed No.:25637514
MicroRNA-33a and let-7e inhibit human colorectal cancer progression by targeting ST8SIA1
PMCID: Pubmed No.:28751193
MiR-26a and miR-26b mediate osteoarthritis progression by targeting FUT4 via NF-κB signaling pathway
PMCID: Pubmed No.:29208566
Combined effect of tris(2-chloroethyl)phosphate and benzo (a) pyrene on the release of IL-6 and IL-8 from HepG2 cells via the EGFR-ERK1/2 signaling pathway
PMCID: Pubmed No.:33233533
l-Theanine attenuates cadmium-induced neurotoxicity through the inhibition of oxidative damage and tau hyperphosphorylation
PMCID: Pubmed No.:27649883
Targeting Gene-Virus-Mediated Manganese Superoxide Dismutase Effectively Suppresses Tumor Growth in Hepatocellular Carcinoma In Vitro and In Vivo
PMCID: Pubmed No.:25414976
Multi-glycoside of Tripterygium wilfordii Hook. f. attenuates glomerulosclerosis in a rat model of diabetic nephropathy by exerting anti-microinflammatory effects without affecting hyperglycemia
PMCID: Pubmed No.:28731135
MicroRNA-218 inhibits the proliferation and metastasis of esophageal squamous cell carcinoma cells by targeting BMI1
PMCID: Pubmed No.:25999024
Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice
PMCID: Pubmed No.:29115561
Proteomic Analysis of HDAC3 Selective Inhibitor in the Regulation of Inflammatory Response of Primary Microglia
PMCID: Pubmed No.:28293439
Manipulation of necroptosis by Porphyromonas gingivalis in periodontitis development
PMCID: Pubmed No.:27449906
Daphnetin reduces endotoxin lethality in mice and decreases LPS-induced inflammation in Raw264.7 cells via suppressing JAK/STATs activation and ROS production
PMCID: Pubmed No.:28409189
Inhibition of diethylnitrosamine-induced liver cancer in rats by Rhizoma paridis saponin
PMCID: Pubmed No.:27451357
Endometrial Receptivity Markers in Mice Stimulated With Raloxifene Versus Clomiphene Citrate and Natural Cycles
PMCID: Pubmed No.:26603317
MLF1IP promotes normal erythroid proliferation and is involved in the pathogenesis of polycythemia vera
PMCID: Pubmed No.:28173615
Changes in astrocyte functional markers and β-amyloid metabolism-related proteins in the early stages of hypercholesterolemia
PMCID: Pubmed No.:26724580
MicroRNA‐106b targets FUT6 to promote cell migration, invasion, and proliferation in human breast cancer
PMCID: Pubmed No.:27519168
Cysteine‐rich buccal gland protein suppressed the proliferation, migration and invasion of hela cells through akt pathway
PMCID: Pubmed No.:28945311
Mild hypothermia protects rat neuronal injury after intracerebral hemorrhage via attenuating endoplasmic reticulum response induced neuron apoptosis
PMCID: Pubmed No.:27771296
Long noncoding RNA NBAT-1 suppresses tumorigenesis and predicts favorable prognosis in ovarian cancer
PMCID: Pubmed No.:28435289
miR-125b inhibited epithelial–mesenchymal transition of triple-negative breast cancer by targeting MAP2K7
PMCID: Pubmed No.:27226726
Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cells
PMCID: Pubmed No.:25421630
ERK5 positively regulates cigarette smoke-induced urocystic epithelial-mesenchymal transition in SV‑40 immortalized human urothelial cells
PMCID: Pubmed No.:26177962
Knockdown of c‑Myc activates Fas-mediated apoptosis and sensitizes A549 cells to radiation
PMCID: Pubmed No.:28849062
SLC7A11, a component of cysteine/glutamate transporter, is a novel biomarker for the diagnosis and prognosis in laryngeal squamous cell carcinoma
PMCID: Pubmed No.:29048627
Protective Effect of l -Theanine on Cadmium-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondria-Mediated Pathway
PMCID: Pubmed No.:26164708
The role of Ca2+ mediated signaling pathways on the effect of taurine against Streptococcus uberis infection
PMCID: Pubmed No.:27527761
Modified Si-Miao-San inhibits inflammation and promotes glucose disposal in adipocytes through regulation of AMP-kinase
PMCID: Pubmed No.:25556062
Matrigel and Activin A promote cell-cell contact and anti-apoptotic activity in cultured human retinal pigment epithelium cells
PMCID: Pubmed No.:27130547
Tris(2‐chloroethyl)phosphate‐induced cell growth arrest via attenuation of SIRT1‐independent PI3K/Akt/mTOR pathway
PMCID: Pubmed No.:26378621
Ubiquitin-specific protease 14 regulates cardiac hypertrophy progression by increasing GSK-3β phosphorylation
PMCID: Pubmed No.:27545607
Bapx1 mediates transforming growth factor-β- induced epithelial-mesenchymal transition and promotes a malignancy phenotype of gastric cancer cells
PMCID: Pubmed No.:28315334
Crosstalk between JNK and NF-κB signaling pathways via HSP27 phosphorylation in HepG2 cells
PMCID: Pubmed No.:25446109
DT-13 ameliorates TNF-α-induced nitric oxide production in the endothelium in vivo and in vitro
PMCID: Pubmed No.:29162452
TPX2 promotes glioma cell proliferation and invasion via activation of the AKT signaling pathway
PMCID: Pubmed No.:28105208
All-trans retinoic acid inhibits migration, invasion and proliferation, and promotes apoptosis in glioma cells in vitro
PMCID: Pubmed No.:26137156
miR-93 enhances cell proliferation by directly targeting CDKN1A in nasopharyngeal carcinoma
PMCID: Pubmed No.:29434867
The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells
PMCID: Pubmed No.:25695094
A novel missense mutation in the ALPL gene causes dysfunction of the protein
PMCID: Pubmed No.:28586049
AQP3 small interfering RNA and PLD2 small interfering RNA inhibit the proliferation and promote the apoptosis of squamous cell carcinoma
PMCID: Pubmed No.:28656282
Serum amyloid A stimulates vascular endothelial growth factor receptor 2 expression and angiogenesis
PMCID: Pubmed No.:26714823
Cadmium pyrithione suppresses tumor growth in vitro and in vivo through inhibition of proteasomal deubiquitinase
PMCID: Pubmed No.:29098502
Clostridium butyricum exerts a neuroprotective effect in a mouse model of traumatic brain injury via the gut‐brain axis
PMCID: Pubmed No.:29193450
Anti-inflammatory Activity of Magnesium Isoglycyrrhizinate Through Inhibition of Phospholipase A2/Arachidonic Acid Pathway
PMCID: Pubmed No.:25691139
Involvement of Prokineticin 2 and Prokineticin Receptor 1 in Lipopolysaccharide-Induced Testitis in Rats
PMCID: Pubmed No.:26490969
MicroRNA-370 Attenuates Hepatic Fibrogenesis by Targeting Smoothened
PMCID: Pubmed No.:25686745
miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway
PMCID: Pubmed No.:29030743
Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload
PMCID: Pubmed No.:25695617
Vaspin protects against LPS‑induced ARDS by inhibiting inflammation, apoptosis and reactive oxygen species generation in pulmonary endothelial cells via the Akt/GSK‑3β pathway
PMCID: Pubmed No.:29039444
MiR-1224-5p acts as a tumor suppressor by targeting CREB1 in malignant gliomas
PMCID: Pubmed No.:25648114
GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells
PMCID: Pubmed No.:26541755
MiR-320a effectively suppresses lung adenocarcinoma cell proliferation and metastasis by regulating STAT3 signals
PMCID: Pubmed No.:28106481
Protective effect of Rabdosia amethystoides (Benth) Hara extract on acute liver injury induced by Concanavalin A in mice through inhibition of TLR4-NF-κB signaling pathway
PMCID: Pubmed No.:26823124
Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response
PMCID: Pubmed No.:27725120
Globular CTRP9 inhibits oxLDL-induced inflammatory response in RAW 264.7 macrophages via AMPK activation
PMCID: Pubmed No.:27188183
Long-term effects of early adolescent stress: dysregulation of hypothalamic–pituitary–adrenal axis and central corticotropin releasing factor receptor 1 expression in adult male rats
PMCID: Pubmed No.:25882722
Lithium chloride administration prevents spatial learning and memory impairment in repeated cerebral ischemia-reperfusion mice by depressing apoptosis and increasing BDNF expression in hippocampus
PMCID: Pubmed No.:26031381
Zeta Inhibitory Peptide as a Novel Therapy to Control Chronic Visceral Hypersensitivity in a Rat Model
PMCID: Pubmed No.:27776136
Overexpression of microRNA-99a Attenuates Cardiac Hypertrophy
PMCID: Pubmed No.:26914935
Regulation of PKM2 and Nrf2-ARE Pathway during Benzoquinone Induced Oxidative Stress in Yolk Sac Hematopoietic Stem Cells
PMCID: Pubmed No.:25437431
Chlorogenic Acid Improves Late Diabetes through Adiponectin Receptor Signaling Pathways in db/db Mice
PMCID: Pubmed No.:25849026
Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways
PMCID: Pubmed No.:25927362
Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells
PMCID: Pubmed No.:26114294
Human Urinary Kallidinogenase Promotes Angiogenesis and Cerebral Perfusion in Experimental Stroke
PMCID: Pubmed No.:26222055
Neuronal and Endothelial Nitric Oxide Synthases in the Paraventricular Nucleus Modulate Sympathetic Overdrive in Insulin-Resistant Rats
PMCID: Pubmed No.:26485682
Micheliolide suppresses LPS-induced neuroinflammatory responses
PMCID: Pubmed No.:29040306
Single Administration of Ultra-Low-Dose Lipopolysaccharide in Rat Early Pregnancy Induces TLR4 Activation in the Placenta Contributing to Preeclampsia
PMCID: Pubmed No.:25853857
Fractalkine/CX3CR1 is involved in the pathogenesis of endometriosis by regulating endometrial stromal cell proliferation and invasion
PMCID: Pubmed No.:27553970
Reduced protein expressions of cytomembrane GABAARβ3 at different postnatal developmental stages of rats exposed prenatally to valproic acid
PMCID: Pubmed No.:28641949
Microwave radiation leading to shrinkage of dendritic spines in hippocampal neurons mediated by SNK-SPAR pathway
PMCID: Pubmed No.:29180226
MiR-21 promotes fibrosis and hypertrophy of ligamentum flavum in lumbar spinal canal stenosis by activating IL-6 expression
PMCID: Pubmed No.:28669725
Suppressing Cyclooxygenase-2 Prevents nonalcoholic and inhibits apoptosis of hepatocytes that are involved in the Akt/p53 signal pathway
PMCID: Pubmed No.:26723251
miR-19 promotes osteosarcoma progression by targeting SOCS6
PMCID: Pubmed No.:28986253
Coatomer subunit beta 2 (COPB2), identified by label-free quantitative proteomics, regulates cell proliferation and apoptosis in human prostate carcinoma cells
PMCID: Pubmed No.:29129687
P53 modulates hepatic insulin sensitivity through NF-κB and p38/ERK MAPK pathways
PMCID: Pubmed No.:29258820
Oral administration of propionic acid during lactation enhances the colonic barrier function
PMCID: Pubmed No.:28335773
Effects of chronic noise on mRNA and protein expression of CRF family molecules and its relationship with p-tau in the rat prefrontal cortex
PMCID: Pubmed No.:27538655
TRAF2 is a Valuable Prognostic Biomarker in Patients with Prostate Cancer
PMCID: Pubmed No.:28855498
Role of gelsolin in cell proliferation and invasion of human hepatocellular carcinoma cells
PMCID: Pubmed No.:26149653
Dahuang Fuzi Decoction Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in Chronic Aristolochic Acid Nephropathy
PMCID: Pubmed No.:28421124
Homoplantaginin Inhibits Palmitic Acid-induced Endothelial Cells Inflammation by Suppressing TLR4 and NLRP3 Inflammasome
PMCID: Pubmed No.:26355761
Cerebrospinal fluid-contacting nucleus mediates nociception via release of fractalkine
PMCID: Pubmed No.:28793053
Activating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro
PMCID: Pubmed No.:28577574
Blockade of LGR4 inhibits proliferation and odonto/osteogenic differentiation of stem cells from apical papillae
PMCID: Pubmed No.:28986711
Curdione attenuates thrombin-induced human platelet activation: β1-tubulin as a potential therapeutic target
PMCID: Pubmed No.:27915054
Lipopolysaccharide enhances OSCC migration by promoting epithelial–mesenchymal transition
PMCID: Pubmed No.:25367215
CART modulates beta-amyloid metabolism-associated enzymes and attenuates memory deficits in APP/PS1 mice
PMCID: Pubmed No.:28743230
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats
PMCID: Pubmed No.:29113791
Development of hybrid-type modified chitosan derivative nanoparticles for the intracellular delivery of midkine-siRNA in hepatocellular carcinoma cells
PMCID: Pubmed No.:29467852
Association between mossy fiber sprouting and expression of semaphorin-3f protein in dentate gyrus of hippocampus in lithium-pilocarpine-induced status epilepticus mouse model
PMCID: Pubmed No.:27745527
Ulinastatin downregulates TLR4 and NF-kB expression and protects mouse brains against ischemia/reperfusion injury
PMCID: Pubmed No.:28191863
Astrocyte-conditioned medium attenuates glutamate-induced apoptotic cell death in primary cultured spinal cord neurons of rats
PMCID: Pubmed No.:26038835
Effects of 4-methylumbelliferone and high molecular weight hyaluronic acid on the inflammation of corneal stromal cells induced by LPS
PMCID: Pubmed No.:27924359
Induced differentiation of human gingival fibroblasts into VSMC-like cells
PMCID: Pubmed No.:28107746
Antitumor effects and the underlying mechanism of licochalcone A combined with 5-fluorouracil in gastric cancer cells
PMCID: Pubmed No.:28454311
miR-215 suppresses proliferation and migration of non-small cell lung cancer cells
PMCID: Pubmed No.:28454402
Role of caspase-10 in the death of acute leukemia cells
PMCID: Pubmed No.:27446483
MicroRNA-203 inhibits cellular proliferation and invasion by targeting Bmi1 in non-small cell lung cancer
PMCID: Pubmed No.:26137120
Expression of AGR2 in pituitary adenomas and its association with tumor aggressiveness
PMCID: Pubmed No.:26722256
Remote limb ischemic postconditioning protects mouse brain against cerebral ischemia/reperfusion injury via upregulating expression of Nrf2, HO-1 and NQO-1 in mice
PMCID: Pubmed No.:26000916
The Expression of microRNA-223 and FAM5C in Cerebral Infarction Patients with Diabetes Mellitus
PMCID: Pubmed No.:26717922
Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway
PMCID: Pubmed No.:28280729
Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis
PMCID: Pubmed No.:27057539
Salidroside protects against kainic acid-induced status epilepticus via suppressing oxidative stress
PMCID: Pubmed No.:26940236
Renal denervation significantly attenuates cardiorenal fibrosis in rats with sustained pressure overload
PMCID: Pubmed No.:27288113
Angiotensin-(1–7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats
PMCID: Pubmed No.:26428223
miRNA-338-3p/CDK4 signaling pathway suppressed hepatic stellate cell activation and proliferation
PMCID: Pubmed No.:28095789
Mitophagy is increased during erythroid differentiation in β-thalassemia
PMCID: Pubmed No.:27796739
Decision Making: Neural Mechanisms: Involvement of protein kinase ζ in the maintenance of hippocampal long-term potentiation in rats with chronic visceral hypersensitivity
PMCID: Pubmed No.:25761958
MiR-15a/16 regulates the growth of myeloma cells, angiogenesis and antitumor immunity by inhibiting Bcl-2, VEGF-A and IL-17 expression in multiple myeloma
PMCID: Pubmed No.:27596960
Serum Amyloid a Promotes Visfatin Expression in Macrophages
PMCID: Pubmed No.:27006946
Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by
upregulating the expression of intergrin α1 and phosphorylation of downstream phospholipase Cγ1
PMCID: Pubmed No.:27484337
β-arrestin2 regulates TRAIL-induced HepG2 cell apoptosis via the Src-extracellular signal-regulated signaling pathway
PMCID: Pubmed No.:27177228
miR-20a induces cisplatin resistance of a human gastric cancer cell line via targeting CYLD
PMCID: Pubmed No.:27357419
Farnesoid X receptor deletion improves cardiac function, structure and remodeling following myocardial infarction in mice Corrigendum in /10.3892/mmr.2017.7698
PMCID: Pubmed No.:28560412
Naringenin attenuates fibroblast activation and inflammatory response in a mechanical stretch-induced hypertrophic scar mouse model
PMCID: Pubmed No.:28849050
Rapamycin protects neurons from brain contusion‑induced inflammatory reaction via modulation of microglial activation
PMCID: Pubmed No.:26458361
FAM172A protein promotes the proliferation of human papillary thyroid carcinoma cells via the p38 mitogen-activated protein kinase pathway
PMCID: Pubmed No.:26573560
The Inhibitory Effect of Eplerenone on Cell Proliferation in the Contralateral Kidneys of Rats with Unilateral Ureteral Obstruction
PMCID: Pubmed No.:28402979
RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal
PMCID: Pubmed No.:27389190
CPNE1 Is a Useful Prognostic Marker and Is Associated with TNF Receptor-Associated Factor 2 (TRAF2) Expression in Prostate Cancer
PMCID: Pubmed No.:29151113
Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells
PMCID: Pubmed No.:26340669
Daphnetin protects oxidative stress‑induced neuronal apoptosis via regulation of MAPK signaling and HSP70 expression
PMCID: Pubmed No.:27588145
miR‑135b inhibits tumour metastasis in prostate cancer by targeting STAT6
PMCID: Pubmed No.:26870245
Oncostatin M was associated with thrombosis in patients with atrial fibrillation
PMCID: Pubmed No.:28471981
Antiviral Activity of Paulownia tomentosa against Enterovirus 71 of Hand, Foot, and Mouth Disease
PMCID: Pubmed No.:25744451
SEW2871 alleviates the severity of caerulein-induced acute pancreatitis in mice
PMCID: Pubmed No.:25948069
Early adolescent stress‐induced changes in prefrontal cortex miRNA‐135a and hippocampal miRNA‐16 in male rats
PMCID: Pubmed No.:28944448
High salt medium activates RhoA/ROCK and downregulates eNOS expression via the upregulation of ADMA
PMCID: Pubmed No.:27175806
Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway
PMCID: Pubmed No.:28560403
Effects of all‑trans retinoic acid on VEGF and HIF‑1α expression in glioma cells under normoxia and hypoxia and its anti‑angiogenic effect in an intracerebral glioma model
PMCID: Pubmed No.:25201493
Chinese herb extract improves liver steatosis by promoting the expression of high molecular weight adiponectin in NAFLD rats
PMCID: Pubmed No.:28849192
Neutrophil extracellular traps contribute to the intestine damage in endotoxemic rats
PMCID: Pubmed No.:25575734
Wushenziye Formula Improves Skeletal Muscle Insulin Resistance in Type 2 Diabetes Mellitus via PTP1B-IRS1-Akt-GLUT4 Signaling Pathway
PMCID: Pubmed No.:29479370
Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide
PMCID: Pubmed No.:26798404
Neuroprotection of Sanhua Decoction against Focal Cerebral Ischemia/Reperfusion Injury in Rats through a Mechanism Targeting Aquaporin 4
PMCID: Pubmed No.:26089944
Curcumin Protects Neurons from Glutamate-Induced Excitotoxicity by Membrane Anchored AKAP79-PKA Interaction Network
PMCID: Pubmed No.:26170881
Expression of decorin in intestinal tissues of mice with inflammatory bowel disease and its correlation with autophagy
PMCID: Pubmed No.:28105121
Unregulated long non‑coding RNA‑AK058003 promotes the proliferation, invasion and metastasis of breast cancer by regulating the expression levels of the γ‑synuclein gene
PMCID: Pubmed No.:26136884
Sheng-Mai-San attenuates contractile dysfunction and structural damage induced by chronic intermittent hypoxia in mice
PMCID: Pubmed No.:26481374
Effects of ethanol extract of Bombax ceiba leaves and its main constituent mangiferin on diabetic nephropathy in mice
PMCID: Pubmed No.:26481374
Increases in the expression of Na+/H+ exchanger 1 and 3 are associated with insulin signalling in the ruminal epithelium
PMCID: Pubmed No.:29027700
MicroRNA-939 down-regulates CD2-associated protein by targeting promoter in HEK-293T cells
PMCID: Pubmed No.:26895305
Yangjing Capsule extract promotes proliferation of GC-1 spg cells via up-regulated POU3F1 pathway
PMCID: Pubmed No.:28154340
Dysregulation of the NLRP3 inflammasome complex and related cytokines in patients with multiple myeloma
PMCID: Pubmed No.:26146985
Orientin Attenuates Cerebral Ischemia/Reperfusion Injury in Rat Model through the AQP-4 and TLR4/NF-κB/TNF-α Signaling Pathway
PMCID: Pubmed No.:28645524
Which play a more important role in the development of large-sized prostates (≥80 ml), androgen receptors or oestrogen receptors? A comparative study
PMCID: Pubmed No.:26685888
Modulation of expression of 17-Hydroxylase/17,20 lyase (CYP17) and P450 aromatase (CYP19) by inhibition of MEK1 in a human ovarian granulosa-like tumor cell line
PMCID: Pubmed No.:26526982
Relaxin Inhibits High Glucose-Induced Matrix Accumulation in Human Mesangial Cells by Interfering with TGF-β1 Production and Mesangial Cells Phenotypic Transition
PMCID: Pubmed No.:26424011
Hypoxia‑inducible factor 1α participates in hypoxia‑induced epithelial‑mesenchymal transition via response gene to complement 32
PMCID: Pubmed No.:28810656
Effect of Advanced Oxidation Protein Products on Articular Cartilage and Synovium in a Rabbit Osteoarthritis Model
PMCID: Pubmed No.:26033998
Bergenin suppresses the growth of colorectal cancer cells by inhibiting PI3K/AKT/mTOR signaling pathway
PMCID: Pubmed No.:37259388
Advanced glycation end products influence mitochondrial fusion-fission dynamics through RAGE in human aortic endothelial cells
PMCID: Pubmed No.:31966653
Role of AP-1 in the tobacco smoke-induced urocystic abnormal cell differentiation and epithelial-mesenchymal transition in vivo
PMCID: Pubmed No.:31966675
Differences in Akt signaling and metabolism gene expression in the right heart, intraventricular septum and left heart of rodents
PMCID: Pubmed No.:26722484
Inhibition of tobacco smoke-induced bladder MAPK activation and epithelial-mesenchymal transition in mice by curcumin
PMCID: Pubmed No.:26191140
Grb2-associated binder 2 silencing impairs growth and migration of H1975 cells via modulation of PI3K-Akt signaling
PMCID: Pubmed No.:26617767
Ethyl acetate extracts of Fructus Ligustri Lucide induce cell apoptosis in human neuroglioma cell
PMCID: Pubmed No.:26064281
Expression of miRNA-1233 in placenta from patients with hypertensive disorder complicating pregnancy and its role in disease pathogenesis
PMCID: Pubmed No.:26309567
MiR181c inhibits ovarian cancer metastasis and progression by targeting PRKCD expression
PMCID: Pubmed No.:26629004
Role of WNT1-inducible-signaling pathway protein 1 in etoposide resistance in lung adenocarcinoma A549 cells
PMCID: Pubmed No.:26628978
A three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics
PMCID: Pubmed No.:27486877
Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice
PMCID: Pubmed No.:27528227
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer
PMCID: Pubmed No.:27563814
Positive expression of NR6A1/CT150 as a predictor of biochemical recurrence-free survival in prostate cancer patients
PMCID: Pubmed No.:28969082
MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells
PMCID: Pubmed No.:27765914
Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway
PMCID: Pubmed No.:27776340
Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stability
PMCID: Pubmed No.:27801666
Long noncoding RNA BX357664 regulates cell proliferation and epithelial-to-mesenchymal transition via inhibition of TGF-β1/p38/HSP27 signaling in renal cell carcinoma
PMCID: Pubmed No.:27806310
MicroRNA-30e reduces cell growth and enhances drug sensitivity to gefitinib in lung carcinoma
PMCID: Pubmed No.:27992364
Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue
PMCID: Pubmed No.:28030827
Increased autophagy in fibroblast-like synoviocytes leads to immune enhancement potential in rheumatoid arthritis
PMCID: Pubmed No.:28053286
Cigarette smoke induced urocystic epithelial mesenchymal transition via MAPK pathways
PMCID: Pubmed No.:28060741
Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases
PMCID: Pubmed No.:28086217
Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells
PMCID: Pubmed No.:28157699
MicroRNA-29b Inhibits Angiogenesis by Targeting VEGFA through the MAPK/ERK and PI3K/Akt Signaling Pathways in Endometrial Carcinoma
PMCID: Pubmed No.:28222438
Interferon alpha antagonizes the anti-hepatoma activity of the oncolytic virus M1 by stimulating anti-viral immunity
PMCID: Pubmed No.:28445966
Invasive Fusobacterium nucleatum activates beta-catenin signaling in colorectal cancer via a TLR4/P-PAK1 cascade
PMCID: Pubmed No.:28423670
Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines
PMCID: Pubmed No.:28410239
Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells
PMCID: Pubmed No.:28422741
Krüppel-like factor 17 inhibits urokinase plasminogen activator gene expression to suppress cell invasion through the Src/p38/MAPK signaling pathway in human lung adenocarcinoma
PMCID: Pubmed No.:28454121
αMSH inhibits adipose inflammation via reducing FoxOs transcription and blocking Akt/JNK pathway in mice
PMCID: Pubmed No.:28514752
p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinoma
PMCID: Pubmed No.:27174914
Crosstalk between the HIF-1 and Toll-like receptor/nuclear factor-κB pathways in the oral squamous cell carcinoma microenvironment
PMCID: Pubmed No.:27191981
Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity
PMCID: Pubmed No.:27248172
4,4′-diaponeurosporene, a C30 carotenoid, effectively activates dendritic cells via CD36 and NF-κB signaling in a ROS independent manner
PMCID: Pubmed No.:27276712
ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway
PMCID: Pubmed No.:27340870
Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling
PMCID: Pubmed No.:27367023
TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype
PMCID: Pubmed No.:27418133
LncRNA-SVUGP2 suppresses progression of hepatocellular carcinoma
PMCID: Pubmed No.:29228655
Heparin-based coacervate of bFGF facilitates peripheral nerve regeneration by inhibiting endoplasmic reticulum stress following sciatic nerve injury
PMCID: Pubmed No.:28624802
Up-regulation of IRF-3 expression through GATA-1 acetylation by histone deacetylase inhibitor in lung adenocarcinoma A549 cells
PMCID: Pubmed No.:29100282
A novel deubiquitinase inhibitor b-AP15 triggers apoptosis in both androgen receptor-dependent and -independent prostate cancers
PMCID: Pubmed No.:28968984
Repression of intestinal transporters and FXR-FGF15 signaling explains bile acids dysregulation in experimental colitis-associated colon cancer
PMCID: Pubmed No.:28969019
Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma
PMCID: Pubmed No.:28938620
Let-7a inhibits migration, invasion and tumor growth by targeting AKT2 in papillary thyroid carcinoma
PMCID: Pubmed No.:29050238
Curcumin reverses benzidine-induced cell proliferation by suppressing ERK1/2 pathway in human bladder cancer T24 cells
PMCID: Pubmed No.:26776764
Upregulation of CD44v6 contributes to acquired chemoresistance via the modulation of autophagy in colon cancer SW480 cells
PMCID: Pubmed No.:26747179
Lithium Ameliorates LPS-Induced Astrocytes Activation Partly via Inhibition of Toll-Like Receptor 4 Expression
PMCID: Pubmed No.:26870942
Decreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivo
PMCID: Pubmed No.:27009808
Metformin and AICAR regulate NANOG expression via the JNK pathway in HepG2 cells independently of AMPK
PMCID: Pubmed No.:26939902
MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer
PMCID: Pubmed No.:26989074
Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells
PMCID: Pubmed No.:27027340
Effect of Golgi phosphoprotein 2 (GOLPH2/GP73) on autophagy in human hepatocellular carcinoma HepG2 cells
PMCID: Pubmed No.:25527157
miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells
PMCID: Pubmed No.:25762621
Bufalin Induces Mitochondrial Pathway-Mediated Apoptosis in Lung Adenocarcinoma Cells
PMCID: Pubmed No.:25556498
Down-regulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis
PMCID: Pubmed No.:29245911
Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation
PMCID: Pubmed No.:28938531
Reduced expression of BMP3 contributes to the development of pulmonary fibrosis and predicts the unfavorable prognosis in IIP patients
PMCID: Pubmed No.:29113323
Angiotensin-(1-7) in Paraventricular Nucleus Contributes to the Enhanced Cardiac Sympathetic Afferent Reflex and Sympathetic Activity in Chronic Heart Failure Rats
PMCID: Pubmed No.:28848201
Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes
PMCID: Pubmed No.:29221131
Cofilin 1 promotes bladder cancer and is regulated by TCF7L2
PMCID: Pubmed No.:29190896
Trimedazidine alleviates pulmonary artery banding-induced acute right heart dysfunction and activates PRAS40 in rats
PMCID: Pubmed No.:29190898
Shikonin reduces tamoxifen resistance through long non-coding RNA uc.57
PMCID: Pubmed No.:29179465
Expression of the β3 subunit of Na+/K+-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway
PMCID: Pubmed No.:29137423
GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1 expression via activation of AMPK/FOXO3a pathway
PMCID: Pubmed No.:26327408
Afatinib reverses multidrug resistance in ovarian cancer via dually inhibiting ATP binding cassette subfamily B member 1
PMCID: Pubmed No.:26317651
8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition
PMCID: Pubmed No.:26316083
Periostin expression in intra-tumoral stromal cells is prognostic and predictive for colorectal carcinoma via creating a cancer-supportive niche
PMCID: Pubmed No.:26556874
Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo
PMCID: Pubmed No.:26625200
MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1
PMCID: Pubmed No.:26673620
Long non-coding RNA CCAT1 modulates neuropathic pain progression through sponging miR-155
PMCID: Pubmed No.:29163801
Inhibition of the SOCS1-JAK2-STAT3 Signaling Pathway Confers Neuroprotection in Rats with Ischemic Stroke
PMCID: Pubmed No.:29130998
NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway
PMCID: Pubmed No.:29296214
Significance of the E3 ubiquitin protein UBR5 as an oncogene and a prognostic biomarker in colorectal cancer
PMCID: Pubmed No.:29296225
Reduction of Uterine Perfusion Pressure Induced Redistribution of Endothelin Receptor Type-B Between the Intima and Media Contributes to the Pathogenesis of Pregnancy-Induced Hypertension
PMCID: Pubmed No.:29216636
miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A
PMCID: Pubmed No.:26023735
Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors
PMCID: Pubmed No.:33186520
Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
PMCID: Pubmed No.:32277911
A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
PMCID: Pubmed No.:29754779
Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing
PMCID: Pubmed No.:30804553
Anesthetic Propofol Promotes Tumor Metastasis in Lungs via GABAAR-Dependent TRIM21 Modulation of Src Expression
PMCID: Pubmed No.:34263559
Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes
PMCID: Pubmed No.:31358756
The δ subunit of F1Fo-ATP synthase is required for pathogenicity of Candida albicans
PMCID: Pubmed No.:34654833
The δ subunit of F1Fo-ATP synthase is required for pathogenicity of Candida albicans
PMCID: Pubmed No.:34654833
GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain
PMCID: Pubmed No.:30010619
Injectable AuNP-HA matrix with localized stiffness enhances the formation of gap junction in engrafted human induced pluripotent stem cell-derived cardiomyocytes and promotes cardiac repair
PMCID: Pubmed No.:34739980
SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis
PMCID: Pubmed No.:31932588
ZZ-dependent regulation of p62/SQSTM1 in autophagy
PMCID: Pubmed No.:30349045
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1
PMCID: Pubmed No.:33484341
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation
PMCID: Pubmed No.:30962431
DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage
PMCID: Pubmed No.:30337542
GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity
PMCID: Pubmed No.:34373748
Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer
PMCID: Pubmed No.:32248842
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer
PMCID: Pubmed No.:34429133
The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression
PMCID: Pubmed No.:31126313
Sirtuin 6 is a negative regulator of FcεRI signaling and anaphylactic responses
PMCID: Pubmed No.:34051221
HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation
PMCID: Pubmed No.:31863069
Sirtuin 6 in preosteoclasts suppresses age- and estrogen deficiency-related bone loss by stabilizing estrogen receptor α
PMCID: Pubmed No.:30787391
Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer
PMCID: Pubmed No.:29685157
Depletion of glioma stem cells by synergistic inhibition of mTOR and c-Myc with a biological camouflaged cascade brain-targeting nanosystem
PMCID: Pubmed No.:33296794
Gold nanoparticles modulate the crosstalk between macrophages and periodontal ligament cells for periodontitis treatment
PMCID: Pubmed No.:30933774
Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats
PMCID: Pubmed No.:29609091
Symmetrical dimethylation of H4R3: A bridge linking DNA damage and repair upon oxidative stress
PMCID: Pubmed No.:32739156
Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
PMCID: Pubmed No.:34731622
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK
PMCID: Pubmed No.:32283380
Sirt1-Overexpressing Mesenchymal Stem Cells Drive the Anti-tumor Effect through Their Pro-inflammatory Capacity
PMCID: Pubmed No.:32027844
CRISPR/Cas9-Mediated miR-29b Editing as a Treatment of Different Types of Muscle Atrophy in Mice
PMCID: Pubmed No.:32222157
A Novel mTORC1/2 Inhibitor (MTI-31) Inhibits Tumor Growth, Epithelial–Mesenchymal Transition, Metastases, and Improves Antitumor Immunity in Preclinical Models of Lung Cancer
PMCID: Pubmed No.:30796032
EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop
PMCID: Pubmed No.:34484860
Controlling the Multiscale Network Structure of Fibers To Stimulate Wound Matrix Rebuilding by Fibroblast Differentiation
PMCID: Pubmed No.:31251577
Repurposing the anthelmintic praziquantel to treat psoriasis
PMCID: Pubmed No.:34363611
Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis
PMCID: Pubmed No.:31541078
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I.
PMCID: Pubmed No.:33408776
KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia
PMCID: Pubmed No.:33456567
Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development
PMCID: Pubmed No.:33754063
Fusobacterium nucleatum Promotes Metastasis in Colorectal Cancer by Activating Autophagy Signaling via the Upregulation of CARD3 Expression
PMCID: Pubmed No.:31903123
SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride
PMCID: Pubmed No.:32308752
The anti-microbial peptide LL-37/CRAMP levels are associated with acute heart failure and can attenuate cardiac dysfunction in multiple preclinical models of heart failure
PMCID: Pubmed No.:32483446
Statin suppresses sirtuin 6 through miR-495, increasing FoxO1-dependent hepatic gluconeogenesis
PMCID: Pubmed No.:33052223
Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac1 and RhoA
PMCID: Pubmed No.:34893584
MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes
PMCID: Pubmed No.:31127093
ATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients
PMCID: Pubmed No.:33846304
A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels
PMCID: Pubmed No.:33934099
Oxytocin receptor induces mammary tumorigenesis through prolactin/p-STAT5 pathway
PMCID: Pubmed No.:34099636
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway
PMCID: Pubmed No.:34108447
HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury
PMCID: Pubmed No.:34666797
Complement factor B in high glucose–induced podocyte injury and diabetic kidney disease
PMCID: Pubmed No.:34622800
S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction
PMCID: Pubmed No.:31694393
Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury
PMCID: Pubmed No.:30782145
Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction
PMCID: Pubmed No.:34837851
SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States
PMCID: Pubmed No.:31914391
Glutathione S-transferases P1 protects breast cancer cell from adriamycin-induced cell death through promoting autophagy
PMCID: Pubmed No.:30683915
HSPA12A is required for adipocyte differentiation and diet-induced obesity through a positive feedback regulation with PPARγ
PMCID: Pubmed No.:30742088
MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2
PMCID: Pubmed No.:29290822
Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake
PMCID: Pubmed No.:31534545
LncRNA KTN1-AS1 promotes the progression of non-small cell lung cancer via sponging of miR-130a-5p and activation of PDPK1
PMCID: Pubmed No.:32820252
ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development
PMCID: Pubmed No.:31116980
Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression
PMCID: Pubmed No.:31539804
HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice
PMCID: Pubmed No.:32086291
Decreased Level of Exosomal miR-5121 Released from Microglia Suppresses Neurite Outgrowth and Synapse Recovery of Neurons Following Traumatic Brain Injury
PMCID: Pubmed No.:33475953
CBP Bromodomain Inhibition Rescues Mice From Lethal Sepsis Through Blocking HMGB1-Mediated Inflammatory Responses
PMCID: Pubmed No.:33603756
HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages.
PMCID: Pubmed No.:34531848
Interferon-Inducible LINC02605 Promotes Antiviral Innate Responses by Strengthening IRF3 Nuclear Translocation.
PMCID: Pubmed No.:34804040
A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells
PMCID: Pubmed No.:33319461
Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation
PMCID: Pubmed No.:30980867
Kynurenic acid/GPR35 axis restricts NLRP3 inflammasome activation and exacerbates colitis in mice with social stress
PMCID: Pubmed No.:30790702
Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29b
PMCID: Pubmed No.:34116237
Inhibiting Protein Kinase Activity of Pyruvate Kinase M2 by SIRT2 Deacetylase Attenuates Psoriasis
PMCID: Pubmed No.:32679047
Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy
PMCID: Pubmed No.:30972284
TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis
PMCID: Pubmed No.:31433805
Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway
PMCID: Pubmed No.:31783879
Fusobacterium nucleatum promotes M2 polarization of macrophages in the microenvironment of colorectal tumours via a TLR4-dependent mechanism
PMCID: Pubmed No.:30121899
SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury
PMCID: Pubmed No.:33854356
Regulation of the integrin αVβ3- actin filaments axis in early osteogenesis of human fibroblasts under cyclic tensile stress
PMCID: Pubmed No.:34620239
Bisphenol A Exposure Induces Apoptosis and Impairs Early Embryonic Development in Xenopus laevis1
PMCID: Pubmed No.:33773307
Hyperactivated Wnt-β-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2
PMCID: Pubmed No.:33109217
PRRX1 deficiency induces mesenchymal‐epithelial transition through PITX2/miR‐200–dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma
PMCID: Pubmed No.:33587761
Functional recovery of a novel knockin mouse model of dysferlinopathy by readthrough of nonsense mutation
PMCID: Pubmed No.:34141825
Curculigoside Ameliorates Bone Loss by Influencing Mesenchymal Stem Cell Fate in Aging Mice.
PMCID: Pubmed No.:34926455
Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells
PMCID: Pubmed No.:34222256
EHD1 impairs decidualization by regulating the Wnt4/β-catenin signaling pathway in recurrent implantation failure
PMCID: Pubmed No.:31707150
Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1
PMCID: Pubmed No.:30093307
LSD1 suppresses invasion, migration and metastasis of luminal breast cancer cells via activation of GATA3 and repression of TRIM37 expression
PMCID: Pubmed No.:31409898
Tspan5 promotes epithelial–mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling
PMCID: Pubmed No.:33955149
Ursolic Acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in NSCLCs harboring EGFR T790M
PMCID: Pubmed No.:31322286
Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation‐related signalling pathways
PMCID: Pubmed No.:31454852
Disrupted hepatic pentose phosphate pathway directly participates in and indirectly promotes cyp3a‐reduction: a new strategy for cyp3a‐mediated drug hepatotoxicity
PMCID: Pubmed No.:31670839
Mir24-2-5p suppresses the osteogenic differentiation with Gnai3 inhibition presenting a direct target via inactivating JNK-p38 MAPK signaling axis
PMCID: Pubmed No.:34803495
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
PMCID: Pubmed No.:33867836
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism
PMCID: Pubmed No.:33250241
Cytotoxicity of hexabromocyclododecane, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane and 1,2,5,6-tetrabromocyclooctane in human SH-SY5Y neuroblastoma cells
PMCID: Pubmed No.:32758930
Cytotoxicity of hexabromocyclododecane, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane and 1,2,5,6-tetrabromocyclooctane in human SH-SY5Y neuroblastoma cells
PMCID: Pubmed No.:32758930
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer
PMCID: Pubmed No.:34804370
MICAL2 Contributes to Gastric Cancer Cell Proliferation by Promoting YAP Dephosphorylation and Nuclear Translocation
PMCID: Pubmed No.:34650666
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps
PMCID: Pubmed No.:33868571
Therapeutic evaluation of acupoint stimulation with needle-scapelon on rat model of degenerative cervical intervertebral discs
PMCID: Pubmed No.:30553194
Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells
PMCID: Pubmed No.:34243598
Differential toxicities of triptolide to immortalized podocytes and the podocytes in vivo
PMCID: Pubmed No.:30551497
Post-transcription mediated Snail stabilization is involved in radiation exposure induced invasion and migration of hepatocarcinoma cells
PMCID: Pubmed No.:29684855
Photothermal and gene therapy combined with immunotherapy to gastric cancer by the gold nanoshell-based system
PMCID: Pubmed No.:31277667
Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents
PMCID: Pubmed No.:33933753
Small regulatory polypeptide of amino acid response negatively relates to poor prognosis and controls hepatocellular carcinoma progression via regulating microRNA-5581-3p/human cardiolipin synthase 1
PMCID: Pubmed No.:30825207
Involvement of TRPV4 in changes in rapidly inactivating potassium channels in the early stage of pilocarpine-induced status epilepticus in mice
PMCID: Pubmed No.:34415059
Long non-coding RNA MCM3AP-AS1 promotes growth and migration through modulating FOXK1 by sponging miR-138-5p in pancreatic cancer
PMCID: Pubmed No.:31830901
HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models
PMCID: Pubmed No.:29113455
The concentration of tumor necrosis factor-α determines its protective or damaging effect on liver injury by regulating Yap activity
PMCID: Pubmed No.:31988281
A lincRNA-p21/miR-181 family feedback loop regulates microglial activation during systemic LPS- and MPTP- induced neuroinflammation
PMCID: Pubmed No.:30038357
Chondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1
PMCID: Pubmed No.:32612115
ALKBH5 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating PTEN expression in an m6A-dependent manner
PMCID: Pubmed No.:34438274
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse
PMCID: Pubmed No.:34695613
Circ-SHPRH suppresses cadmium-induced transformation of human bronchial epithelial cells by regulating QKI expression via miR-224–5p
PMCID: Pubmed No.:34082244
TRPV3 enhances skin keratinocyte proliferation through EGFR-dependent signaling pathways
PMCID: Pubmed No.:32535744
Vacuolar Membrane ATPase Activity 21 Predicts a Favorable Outcome and Acts as a Suppressor in Colorectal Cancer
PMCID: Pubmed No.:33680927
Serpinc1 Acts as a Tumor Suppressor in Hepatocellular Carcinoma Through Inducing Apoptosis and Blocking Macrophage Polarization in an Ubiquitin-Proteasome Manner
PMCID: Pubmed No.:34881176
Screening of MicroRNA Related to Irradiation Response and the Regulation Mechanism of miRNA-96-5p in Rectal Cancer Cells
PMCID: Pubmed No.:34458143
NGF Signaling Interacts With the Hippo/YAP Pathway to Regulate Cervical Cancer Progression
PMCID: Pubmed No.:34722240
PTIP Inhibits Cell Invasion in Esophageal Squamous Cell Carcinoma via Modulation of EphA2 Expression
PMCID: Pubmed No.:33833989
Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer
PMCID: Pubmed No.:33968724
Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer
PMCID: Pubmed No.:33968724
Eukaryotic Translation Initiation Factor 3 Subunit B Is a Promoter in the Development and Progression of Pancreatic Cancer
PMCID: Pubmed No.:33996561
The Exocrine Differentiation and Proliferation Factor (EXDPF) Gene Promotes Ovarian Cancer Tumorigenesis by Up-Regulating DNA Replication Pathway.
PMCID: Pubmed No.:34041032
Atorvastatin alleviates microglia-mediated neuroinflammation via modulating the microbial composition and the intestinal barrier function in ischemic stroke mice
PMCID: Pubmed No.:33279615
Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis
PMCID: Pubmed No.:30030103
Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II
PMCID: Pubmed No.:30502455
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury
PMCID: Pubmed No.:34937917
S-nitrosylation of c-Jun N-terminal kinase mediates pressure overload-induced cardiac dysfunction and fibrosis
PMCID: Pubmed No.:34011968
Dihydromyricetin ameliorates vascular calcification in chronic kidney disease by targeting AKT signaling
PMCID: Pubmed No.:34643227
Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer
PMCID: Pubmed No.:30250021
Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance
PMCID: Pubmed No.:33008458
Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy
PMCID: Pubmed No.:35509816
Sirt3 Protects Against Thoracic Aortic Dissection Formation by Reducing Reactive Oxygen Species, Vascular Inflammation, and Apoptosis of Smooth Muscle Cells
PMCID: Pubmed No.:34095262
Long noncoding RNA Q associates with Sox2 and is involved in the maintenance of pluripotency in mouse embryonic stem cells
PMCID: Pubmed No.:32277787
Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis
PMCID: Pubmed No.:31189885
Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis
PMCID: Pubmed No.:31189885
Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement
PMCID: Pubmed No.:31522191
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival
PMCID: Pubmed No.:31740658
Regulatory roles of miR-22/Redd1-mediated mitochondrial ROS and cellular autophagy in ionizing radiation-induced BMSC injury
PMCID: Pubmed No.:30846680
TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice
PMCID: Pubmed No.:31097691
miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma
PMCID: Pubmed No.:29531296
miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma
PMCID: Pubmed No.:29531296
CDC42 promotes vascular calcification in chronic kidney disease
PMCID: Pubmed No.:31397884
LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis
PMCID: Pubmed No.:31982491
Mangiferin activates Nrf2 to attenuate cardiac fibrosis via redistributing glutaminolysis-derived glutamate
PMCID: Pubmed No.:32353588
Scutellarin, a modulator of mTOR, attenuates hepatic insulin resistance by regulating hepatocyte lipid metabolism via SREBP-1c suppression
PMCID: Pubmed No.:31828866
Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway
PMCID: Pubmed No.:34859513
Tanshinone IIA Activates Nuclear Factor-Erythroid 2-Related Factor 2 to Restrain Pulmonary Fibrosis via Regulation of Redox Homeostasis and Glutaminolysis
PMCID: Pubmed No.:30105924
Fusobacterium nucleatum Activates Endoplasmic Reticulum Stress to Promote Crohn’s Disease Development via the Upregulation of CARD3 Expression
PMCID: Pubmed No.:32153411
Combined Treatment With 2-(2-Benzofu-Ranyl)-2-Imidazoline and Recombinant Tissue Plasminogen Activator Protects Blood–Brain Barrier Integrity in a Rat Model of Embolic Middle Cerebral Artery Occlusion
PMCID: Pubmed No.:32595494
Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer
PMCID: Pubmed No.:34305593
A Single, Acute Astragaloside IV Therapy Protects Cardiomyocyte Through Attenuating Superoxide Anion-Mediated Accumulation of Autophagosomes in Myocardial Ischemia-Reperfusion Injury
PMCID: Pubmed No.:34349641
Glycoproteins From Rabdosia japonica var. glaucocalyx Regulate Macrophage Polarization and Alleviate Lipopolysaccharide-Induced Acute Lung Injury in Mice via TLR4/NF-κB Pathway
PMCID: Pubmed No.:34366849
Effect of tryptase on mouse brain microvascular endothelial cells via protease-activated receptor 2
PMCID: Pubmed No.:30170602
NLRP3 Inflammasome-Dependent Increases in High Mobility Group Box 1 Involved in the Cognitive Dysfunction Caused by Tau-Overexpression
PMCID: Pubmed No.:34539383
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children
PMCID: Pubmed No.:30659323
A new gold(I) complex-Au(PPh3)PT is a deubiquitinase inhibitor and inhibits tumor growth
PMCID: Pubmed No.:30527624
Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta
PMCID: Pubmed No.:32949999
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth
PMCID: Pubmed No.:34774047
Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration
PMCID: Pubmed No.:34517891
RPL35A is a key promotor involved in the development and progression of gastric cancer
PMCID: Pubmed No.:34535139
The effects of MEX3A knockdown on proliferation, apoptosis and migration of osteosarcoma cells
PMCID: Pubmed No.:33827584
Trichostatin A downregulates bromodomain and extra-terminal proteins to suppress osimertinib resistant non-small cell lung carcinoma
PMCID: Pubmed No.:33858423
Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo
PMCID: Pubmed No.:33931059
CircRNA NALCN acts as an miR-493-3p sponge to regulate PTEN expression and inhibit glioma progression
PMCID: Pubmed No.:34112159
Network analysis of KLF5 targets showing the potential oncogenic role of SNHG12 in colorectal cancer
PMCID: Pubmed No.:32943987
Suppression of CCDC6 sensitizes tumor to oncolytic virus M1
PMCID: Pubmed No.:33338804
Real-Time Visualization and Quantification of Oncolytic M1 Virus In Vitro and In Vivo
PMCID: Pubmed No.:33504253
Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice
PMCID: Pubmed No.:31048563
Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer
PMCID: Pubmed No.:34623971
Near-infrared light-activatable siRNA delivery by microcapsules for combined tumour therapy
PMCID: Pubmed No.:29527926
miR-33a-5p enhances the sensitivity of lung adenocarcinoma cells to celastrol by regulating mTOR signaling
PMCID: Pubmed No.:29484434
Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway
PMCID: Pubmed No.:31234944
MicroRNA-663 facilitates the growth, migration and invasion of ovarian cancer cell by inhibiting TUSC2
PMCID: Pubmed No.:30944041
Baicalin regulates SirT1/STAT3 pathway and restrains excessive hepatic glucose production
PMCID: Pubmed No.:30144531
Glycochenodeoxycholate promotes the metastasis of gallbladder cancer cells by inducing epithelial to mesenchymal transition via activation of SOCS3/JAK2/STAT3 signaling pathway
PMCID: Pubmed No.:31347168
Dynamic recognition and repair of DNA complex damage
PMCID: Pubmed No.:30537094
Phosphoinositide 3‐kinase/protein kinase B inhibition restores regulatory T cell's function in pulmonary sarcoidosis
PMCID: Pubmed No.:30945303
Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy
PMCID: Pubmed No.:30585174
Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis
PMCID: Pubmed No.:33889074
Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice
PMCID: Pubmed No.:30699097
Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke
PMCID: Pubmed No.:34553133
TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency
PMCID: Pubmed No.:31959867
Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes
PMCID: Pubmed No.:31028245
Osterix regulates corticalization for longitudinal bone growth via integrin β3 expression
PMCID: Pubmed No.:30022046
Autophagy Activation is Associated with Neuroprotection in Diabetes-associated Cognitive Decline
PMCID: Pubmed No.:31788335
Involvement of the MiR-181b-5p/HMGB1 Pathway in Ang II-induced Phenotypic Transformation of Smooth Muscle Cells in Hypertension
PMCID: Pubmed No.:31011475
Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain
PMCID: Pubmed No.:29896426
Baicalin protects against insulin resistance and metabolic dysfunction through activation of GALR2/GLUT4 signaling
PMCID: Pubmed No.:34923235
Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility
PMCID: Pubmed No.:31005715
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Accelerate Cutaneous Wound Healing by Enhancing Angiogenesis through Delivering Angiopoietin-2
PMCID: Pubmed No.:32613452
A-kinase-interacting protein 1 facilitates growth and metastasis of gastric cancer cells via Slug-induced epithelial-mesenchymal transition
PMCID: Pubmed No.:31020809
Lactobacillus Protects Against S. Typhimurium–Induced Intestinal Inflammation by Determining the Fate of Epithelial Proliferation and Differentiation
PMCID: Pubmed No.:31953989
Fecal Microbiota Transplantation Protects the Intestinal Mucosal Barrier by Reconstructing the Gut Microbiota in a Murine Model of Sepsis
PMCID: Pubmed No.:34631604
LncRNA ENSMUST00000155383 is Involved in the Improvement of DPP-4 Inhibitor MK-626 on Vascular Endothelial Function by Modulating Cacna1c-Mediated Ca2+ Influx in Hypertensive Mice
PMCID: Pubmed No.:34368236
MicroRNA‐219 decreases hippocampal long‐term potentiation inhibition and hippocampal neuronal cell apoptosis in type 2 diabetes mellitus mice by suppressing the NMDAR signaling pathway
PMCID: Pubmed No.:29804319
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke
PMCID: Pubmed No.:34156153
Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30
PMCID: Pubmed No.:34381024
c-Myc Is a Major Determinant for Antitumor Activity of Aurora A Kinase Inhibitor MLN8237 in Thyroid Cancer
PMCID: Pubmed No.:30226440
The Krüppel-like factor 15-NFATc1 axis ameliorates podocyte injury: a novel rationale for using glucocorticoids in proteinuria diseases
PMCID: Pubmed No.:32478397
Targeting POLE2 Creates a Novel Vulnerability in Renal Cell Carcinoma via Modulating Stanniocalcin 1
PMCID: Pubmed No.:33644060
Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Random Skin Flaps via ROS Elimination
PMCID: Pubmed No.:33898433
Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A–Smad2/3 in rats following myocardial infarction
PMCID: Pubmed No.:33932887
Dysregulation of UDP-glucuronosyltransferases in CCl4 induced liver injury rats
PMCID: Pubmed No.:32380060
The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply
PMCID: Pubmed No.:31425655
Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR-miR-429 pathway
PMCID: Pubmed No.:33811696
Proteomics and bioinformatics reveal insights into neuroinflammation in the acute to subacute phases in rat models of spinal cord contusion injury
PMCID: Pubmed No.:34143440
Cullin 2-RBX1 E3 ligase and USP2 regulate antithrombin ubiquitination and stability
PMCID: Pubmed No.:34324733
EIF3H interacts with PDCD4 enhancing lung adenocarcinoma cell metastasis
PMCID: Pubmed No.:32064160
The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO
PMCID: Pubmed No.:34714466
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis
PMCID: Pubmed No.:31718671
Circ_0088194 Promotes the Invasion and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the miR-766-3p/MMP2 Axis
PMCID: Pubmed No.:33692802
Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells
PMCID: Pubmed No.:34157397
Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats
PMCID: Pubmed No.:31827689
Farrerol Directly Targets GSK-3β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries
PMCID: Pubmed No.:32082480
Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits
PMCID: Pubmed No.:32685087
ERK1/2-HNF4α axis is involved in epigallocatechin-3-gallate inhibition of HBV replication
PMCID: Pubmed No.:31554961
Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression
PMCID: Pubmed No.:30150788
Isoflavones enhance pharmacokinetic exposure of active lovastatin acid via the upregulation of carboxylesterase in high-fat diet mice after oral administration of Xuezhikang capsules
PMCID: Pubmed No.:29921884
Oral administration of curcumin ameliorates pulmonary fibrosis in mice through 15d-PGJ2-mediated induction of hepatocyte growth factor in the colon
PMCID: Pubmed No.:32694760
Quercetin prevents bone loss in hindlimb suspension mice via stanniocalcin 1-mediated inhibition of osteoclastogenesis
PMCID: Pubmed No.:32934346
Berberine inhibits colorectal tumor growth by suppressing SHH secretion
PMCID: Pubmed No.:32958873
Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor
PMCID: Pubmed No.:33820450
Long noncoding RNA HOTAIR promotes renal cell carcinoma malignancy through alpha‐2, 8‐sialyltransferase 4 by sponging microRNA‐124
PMCID: Pubmed No.:30105850
Silent information regulator 1 suppresses epithelial-to-mesenchymal transition in lung cancer cells via its regulation of mitochondria status
PMCID: Pubmed No.:34119539
Proteomes analysis reveals the involvement of autophagy in AD-like neuropathology induced by noise exposure and ApoE4
PMCID: Pubmed No.:31228807
BabaoDan attenuates high-fat diet-induced non-alcoholic fatty liver disease via activation of AMPK signaling
PMCID: Pubmed No.:31548878
Modification of α2,6‐sialylation mediates the invasiveness and tumorigenicity of non‐small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway
PMCID: Pubmed No.:29981167
The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome
PMCID: Pubmed No.:31914678
Pharmacological activation of ERβ by arctigenin maintains the integrity of intestinal epithelial barrier in inflammatory bowel diseases
PMCID: Pubmed No.:31908053
The opposite functions of miR‐24 in the osteogenesis and adipogenesis of adipose‐derived mesenchymal stem cells are mediated by the HOXB7/β‐catenin complex
PMCID: Pubmed No.:32413244
PHD3 mediates denervation skeletal muscle atrophy through Nf‐κB signal pathway
PMCID: Pubmed No.:33749901
Tristetraprolin destabilizes NOX2 mRNA and protects dopaminergic neurons from oxidative damage in Parkinson's disease
PMCID: Pubmed No.:32954540
Glutathione S-transferases P1-mediated interleukin-6 in tumor-associated macrophages augments drug-resistance in MCF-7 breast cancer
PMCID: Pubmed No.:33080187
3-Bromopyruvate regulates the status of glycolysis and BCNU sensitivity in human hepatocellular carcinoma cells
PMCID: Pubmed No.:32330495
MrgprX2 regulates mast cell degranulation through PI3K/AKT and PLCγ signaling in pseudo-allergic reactions
PMCID: Pubmed No.:34920312
The levels and significance of inflammasomes in the mouse retina following optic nerve crush
PMCID: Pubmed No.:30939414
Ulinastatin mediates suppression of regulatory T cells through TLR4/NF-κB signaling pathway in murine sepsis
PMCID: Pubmed No.:30261464
The PICK1/TLR4 complex on microglia is involved in the regulation of LPS-induced sepsis-associated encephalopathy
PMCID: Pubmed No.:34500285
mTOR- and SGK-Mediated Connexin 43 Expression Participates in Lipopolysaccharide-Stimulated Macrophage Migration through the iNOS/Src/FAK Axis
PMCID: Pubmed No.:30341186
Serum- and glucocorticoid-inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1
PMCID: Pubmed No.:33724645
l-Theanine attenuates neointimal hyperplasia via suppression of vascular smooth muscle cell phenotypic modulation
PMCID: Pubmed No.:32402912
Pro‐inflammatory role of high‐mobility group box‐1 on brain mast cells via the RAGE/NF‐κB pathway
PMCID: Pubmed No.:31520526
The Antioxidant MitoQ Protects Against CSE-Induced Endothelial Barrier Injury and Inflammation by Inhibiting ROS and Autophagy in Human Umbilical Vein Endothelial Cells
PMCID: Pubmed No.:31337974
A Long Non-coding RNA Lnc712 Regulates Breast Cancer Cell Proliferation
PMCID: Pubmed No.:31892853
RRM2 is a potential prognostic biomarker with functional significance in glioma
PMCID: Pubmed No.:30745840
Metformin suppresses inflammation and apoptosis of myocardiocytes by inhibiting autophagy in a model of ischemia-reperfusion injury
PMCID: Pubmed No.:32792857
Glibenclamide Targets Sulfonylurea Receptor 1 to Inhibit p70S6K Activity and Upregulate KLF4 Expression to Suppress Non-Small Cell Lung Carcinoma
PMCID: Pubmed No.:31341030
Knockdown of Kremen2 Inhibits Tumor Growth and Migration in Gastric Cancer
PMCID: Pubmed No.:33489867
Inhibition of CDC25B With WG-391D Impedes the Tumorigenesis of Ovarian Cancer
PMCID: Pubmed No.:31024841
Autophagy Induced by Proteasomal DUB Inhibitor NiPT Restricts NiPT-Mediated Cancer Cell Death
PMCID: Pubmed No.:32292717
Discovery of coumarin-derived imino sulfonates as a novel class of potential cardioprotective agents
PMCID: Pubmed No.:31629165
Reduced miR-203 predicts metastasis and poor survival in esophageal carcinoma
PMCID: Pubmed No.:31844033
β-arrestin2 alleviates L-dopa–induced dyskinesia via lower D1R activity in Parkinson’s rats
PMCID: Pubmed No.:31891566
TYRO3 facilitates cell growth and metastasis via activation of the Wnt/β-catenin signaling pathway in human gastric cancer cells
PMCID: Pubmed No.:32018224
Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation
PMCID: Pubmed No.:32365333
Protective effects of ginseng stem-leaf saponins on D-galactose-induced reproductive injury in male mice
PMCID: Pubmed No.:33714944
Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization
PMCID: Pubmed No.:29753749
A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan
PMCID: Pubmed No.:30733972
Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice
PMCID: Pubmed No.:30946910
CircSPAG16 suppresses cadmium-induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt
PMCID: Pubmed No.:34081812
miR-103/107 promote ER stress-mediated apoptosis via targeting the Wnt3a/β-catenin/ATF6 pathway in preadipocytes
PMCID: Pubmed No.:29483204
GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner
PMCID: Pubmed No.:31324725
A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway
PMCID: Pubmed No.:31396207
Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses
PMCID: Pubmed No.:30333836
A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis
PMCID: Pubmed No.:30425719
Gasdermin D serves as a key executioner of pyroptosis in experimental cerebral ischemia and reperfusion model both in vivo and in vitro
PMCID: Pubmed No.:30600840
Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats
PMCID: Pubmed No.:32084453
Astrocytic Yes-associated protein attenuates cerebral ischemia-induced brain injury by regulating signal transducer and activator of transcription 3 signaling
PMCID: Pubmed No.:32750359
Clinopodium chinense Attenuates Palmitic Acid-Induced Vascular Endothelial Inflammation and Insulin Resistance through TLR4-Mediated NF-κB and MAPK Pathways
PMCID: Pubmed No.:30776912
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS‐G12D mutation and P53 knockout
PMCID: Pubmed No.:31410985
Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK‐ERK pathway
PMCID: Pubmed No.:30907511
Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK‐ERK pathway
PMCID: Pubmed No.:30907511
MICAL1 facilitates breast cancer cell proliferation via ROS‐sensitive ERK/cyclin D pathway
PMCID: Pubmed No.:29524295
6‐Gingerol Improves Ectopic Lipid Accumulation, Mitochondrial Dysfunction, and Insulin Resistance in Skeletal Muscle of Ageing Rats: Dual Stimulation of the AMPK/PGC‐1α Signaling Pathway via Plasma Adiponectin and Muscular AdipoR1
PMCID: Pubmed No.:30575271
AR-mTOR-SRF Axis Regulates HMMR Expression in Human Prostate Cancer Cells
PMCID: Pubmed No.:34099592
Galectin-3 Interacts with C/EBPβ and Upregulates Hyaluronan-Mediated Motility Receptor Expression in Gastric Cancer
PMCID: Pubmed No.:31822520
Mechanical Strain Regulates Myofibroblast Differentiation of Human Scleral Fibroblasts by YAP
PMCID: Pubmed No.:34658907
OCT4B-190 protects against ischemic stroke by modulating GSK-3β/HDAC6
PMCID: Pubmed No.:30981804
Sodium-glucose co-transporter-2 (SGLT-2) inhibition reduces glucose uptake to induce breast cancer cell growth arrest through AMPK/mTOR pathway
PMCID: Pubmed No.:33068934
Rhodiola crenulata root extract ameliorates fructose-induced hepatic steatosis in rats: Association with activating autophagy
PMCID: Pubmed No.:32007914
Synergistic antitumour effects of triptolide plus 10-hydroxycamptothecin onbladder cancer
PMCID: Pubmed No.:31063955
Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration
PMCID: Pubmed No.:32526459
FTO inhibits UPRmt-induced apoptosis by activating JAK2/STAT3 pathway and reducing m6A level in adipocytes
PMCID: Pubmed No.:34212271
CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration
PMCID: Pubmed No.:34412565
A potential probiotic bacterium for antipsychotic-induced metabolic syndrome: mechanisms underpinning how Akkermansia muciniphila subtype improves olanzapine-induced glucose homeostasis in mice
PMCID: Pubmed No.:34046717
PM2.5 promotes plaque vulnerability at different stages of atherosclerosis and the formation of foam cells via TLR4/MyD88/NFκB pathway
PMCID: Pubmed No.:30921699
MiR‐34a inhibits the proliferation, migration, and invasion of oral squamous cell carcinoma by directly targeting SATB2
PMCID: Pubmed No.:31663131
Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice
PMCID: Pubmed No.:31988048
The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response
PMCID: Pubmed No.:29420297
Long Noncoding RNA NRAV Promotes Respiratory Syncytial Virus Replication by Targeting the MicroRNA miR-509-3p/Rab5c Axis To Regulate Vesicle Transportation
PMCID: Pubmed No.:32102886
Deficiency of the IRE1α-Autophagy Axis Enhances the Antitumor Effects of the Oncolytic Virus M1
PMCID: Pubmed No.:29263275
Resolvin D1 Attenuates Innate Immune Reactions in Experimental Subarachnoid Hemorrhage Rat Model
PMCID: Pubmed No.:33411245
SIRT1 induces the adipogenic differentiation of mouse embryonic stem cells by regulating RA-induced RAR expression via NCOR1 acetylation
PMCID: Pubmed No.:32217463
m6A methyltransferase METTL3 promotes retinoblastoma progression via PI3K/AKT/mTOR pathway
PMCID: Pubmed No.:33090698
Ubiquitin‐specific protease 2 regulates Ang Ⅱ–induced cardiac fibroblasts activation by up‐regulating cyclin D1 and stabilizing β‐catenin in vitro
PMCID: Pubmed No.:33314748
Cistanche deserticola polysaccharide induces melanogenesis in melanocytes and reduces oxidative stress via activating NRF2/HO‐1 pathway
PMCID: Pubmed No.:32096914
Lentinan protects against pancreatic β‐cell failure in chronic ethanol consumption‐induced diabetic mice via enhancing β‐cell antioxidant capacity
PMCID: Pubmed No.:33837638
Zinc finger protein 91 loss induces cardiac hypertrophy through adenosine A1 receptor down‐regulation under pressure overload status
PMCID: Pubmed No.:32677376
IL‐27 Rα+ cells promoted allorejection via enhancing STAT1/3/5 phosphorylation
PMCID: Pubmed No.:32761753
LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway
PMCID: Pubmed No.:32881263
HIF‐1α‐induced up‐regulation of microRNA‐126 contributes to the effectiveness of exercise training on myocardial angiogenesis in myocardial infarction rats
PMCID: Pubmed No.:32939968
Alpha B‐crystallin promotes the invasion and metastasis of gastric cancer via NF‐κB‐induced epithelial‐mesenchymal transition
PMCID: Pubmed No.:29566309
ZAG alleviates HFD-induced insulin resistance accompanied with decreased lipid depot in skeletal muscle in mice
PMCID: Pubmed No.:30318474
Aging-Related Neural Disruption Might Predispose to Postoperative Cognitive Impairment Following Surgical Trauma
PMCID: Pubmed No.:33967044
CCNI2 plays a promoting role in the progression of colorectal cancer
PMCID: Pubmed No.:33620152
Flotillin-1 promotes progression and dampens chemosensitivity to cisplatin in gastric cancer via ERK and AKT signaling pathways
PMCID: Pubmed No.:34774850
The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway
PMCID: Pubmed No.:34425100
L-theanine inhibits foam cell formation via promoting the scavenger receptor A degradation
PMCID: Pubmed No.:34004205
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy
PMCID: Pubmed No.:34087223
Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression
PMCID: Pubmed No.:30775800
Long noncoding RNA LINC00961 inhibits cell proliferation and induces cell apoptosis in human non–small cell lung cancer
PMCID: Pubmed No.:30010215
Polyglutamine protein in tumor cells sensitizes tumor cells to natural killer cell cytolysis
PMCID: Pubmed No.:32580073
Downregulating Heparanase-Induced Vascular Normalization: A New Approach To Increase the Bioavailability of Chemotherapeutics in Solid Tumors
PMCID: Pubmed No.:30059227
Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth
PMCID: Pubmed No.:32128976
Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements
PMCID: Pubmed No.:33446747
Histone Deacetylase Inhibitor Alleviates the Neurodegenerative Phenotypes and Histone Dysregulation in Presenilins-Deficient Mice
PMCID: Pubmed No.:29867447
Hydrogen sulfide attenuates oxidative stress-induced NLRP3 inflammasome activation via S-sulfhydrating c-Jun at Cys269 in macrophages
PMCID: Pubmed No.:29859240
Immune response in piglets orally immunized with recombinant Bacillus subtilis expressing the capsid protein of porcine circovirus type 2
PMCID: Pubmed No.:32046726
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice
PMCID: Pubmed No.:30797958
Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis
PMCID: Pubmed No.:29386287
The role of Snf5 in the osteogenic differentiation potential during replicative senescence of rat mesenchymal stromal cells
PMCID: Pubmed No.:29398003
Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor
PMCID: Pubmed No.:32018210
Rhein protects the myocardiac cells against hypoxia/reoxygention-induced injury by suppressing GSK3β activity
PMCID: Pubmed No.:30466606
Paeoniflorin modulates gut microbial production of indole-3-lactate and epithelial autophagy to alleviate colitis in mice
PMCID: Pubmed No.:33002829
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation
PMCID: Pubmed No.:30700991
TRPC6 contributes to LPS-induced inflammation through ERK1/2 and p38 pathways in bronchial epithelial cells
PMCID: Pubmed No.:29141922
Adrenomedullin Receptors in Rats with Obesity-Related Hypertension
PMCID: Pubmed No.:30276527
Downregulation of long noncoding RNA SNHG1 inhibits cell proliferation, metastasis, and invasion by suppressing the Notch‐1 signaling pathway in pancreatic cancer
PMCID: Pubmed No.:30520072
Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival
PMCID: Pubmed No.:33796027
1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB
PMCID: Pubmed No.:30930772
Non-canonical Notch Signaling Regulates Actin Remodeling in Cell Migration by Activating PI3K/AKT/Cdc42 Pathway
PMCID: Pubmed No.:31057403
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.