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GAPDH polyclonal antibody AP0063
  • Western blot (WB) analysis of GAPDH pAb at 1:5000/1:10000/1:20000/1:40000 dilution Lane1:L02 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:MG63 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Rat(40ug) Lane7:The Brain tissue lysate of Mouse(40ug)
Product NameGAPDH polyclonal antibody
Catalog No.AP0063
Swiss-ProtN/A
Host Rabbit
ReactivityHuman,Mouse,Rat(not applicable to some tissue)
ApplicationsWB
Application_allWB:1:5000~1:20000
BiowMW~ 36 kDa
Alternative NameGlyceraldehyde-3-phosphate dehydrogenase; GAPDH; GAPD
Purification&PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ConjugateUnconjugated
ModificationUnmodified
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Product Name :
GAPDH polyclonal antibody
Background :
Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits.
Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
GAPDH polyclonal antibody detects endogenous levels of GAPDH protein.
Immunogen :
Recombinant full length Human GAPDH.
Conjugate :
Unconjugated
Modification :
Unmodified
  • Western blot (WB) analysis of GAPDH pAb at 1:5000/1:10000/1:20000/1:40000 dilution Lane1:L02 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:MG63 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Rat(40ug) Lane7:The Brain tissue lysate of Mouse(40ug)
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Dysfunction PMCID:    Pubmed No.:26869350 The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells PMCID:    Pubmed No.:27060717 Helicobacter pylori inhibits the cleavage of TRAF1 via a CagA-dependent mechanism PMCID:    Pubmed No.:28082808 Activation of PPARγ Ameliorates Spatial Cognitive Deficits through Restoring Expression of AMPA Receptors in Seipin Knock-Out Mice PMCID:    Pubmed No.:26818512 Soluble receptor for advanced glycation end-products protects against ischemia/reperfusion-induced myocardial apoptosis via regulating the ubiquitin proteasome system PMCID:    Pubmed No.:26878774 Wogonoside inhibits invasion and migration through suppressing TRAF2/4 expression in breast cancer PMCID:    Pubmed No.:28774312 Akt1 signaling coordinates BMP signaling and β-catenin activity to regulate second heart field progenitor development PMCID:    Pubmed No.:25670795 Persistent mitoKATP Activation Is Involved in the Isoflurane-induced Cytotoxicity PMCID:    Pubmed No.:26803495 The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1 PMCID:    Pubmed No.:26808085 Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner PMCID:    Pubmed No.:26054569 miR‐1470 mediates lapatinib induced p27 upregulation by targeting c‐jun PMCID:    Pubmed No.:25545366 Beneficial effects of renal denervation on cardiac angiogenesis in rats with prolonged pressure overload PMCID:    Pubmed No.:27575955 Adipose afferent reflex response to insulin is mediated by melanocortin 4 type receptors in the paraventricular nucleus in insulin resistance rats PMCID:    Pubmed No.:25846948 Methylation of DIRAS1 promotes colorectal cancer progression and may serve as a marker for poor prognosis PMCID:    Pubmed No.:28491151 Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue PMCID:    Pubmed No.:27746687 Cutting Edge: TRAF6 Mediates TLR/IL-1R Signaling–Induced Nontranscriptional Priming of the NLRP3 Inflammasome PMCID:    Pubmed No.:28739881 Endoplasmic reticulum ribosome-binding protein 1, RRBP1, promotes progression of colorectal cancer and predicts an unfavourable prognosis PMCID:    Pubmed No.:26196185 Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy PMCID:    Pubmed No.:29296531 Ulinastatin protects brain against cerebral ischemia/reperfusion injury through inhibiting MMP-9 and alleviating loss of ZO-1 and occludin proteins in mice PMCID:    Pubmed No.:29291404 Class III PI3K-mediated prolonged activation of autophagy plays a critical role in the transition of cardiac hypertrophy to heart failure PMCID:    Pubmed No.:25851780 d‐Chiro inositol ameliorates endothelial dysfunction via inhibition of oxidative stress and mitochondrial fission PMCID:    Pubmed No.:28087886 MiR-582-5p/miR-590-5p targeted CREB1/CREB5–NF-κB signaling and caused opioid-induced immunosuppression in human monocytes PMCID:    Pubmed No.:26978739 eEF2K promotes progression and radioresistance of esophageal squamous cell carcinoma PMCID:    Pubmed No.:28431753 Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease PMCID:    Pubmed No.:28381600 The role of the miR-31/FIH1 pathway in TGF-β-induced liver fibrosis PMCID:    Pubmed No.:25728779 MicroRNA-132 promotes estradiol synthesis in ovarian granulosa cells via translational repression of Nurr1 PMCID:    Pubmed No.:26282993 The influence of maternal dietary fat on the fatty acid composition and lipid metabolism in the subcutaneous fat of progeny pigs PMCID:    Pubmed No.:26047981 2β, 3β, 23-trihydroxy-urs-12-ene-28-olic acid (TUA) isolated from Actinidia chinensis Radix inhibits NCI-H460 cell proliferation by decreasing NF-κB expression PMCID:    Pubmed No.:26134000 Malat1 regulates serum response factor through miR-133 as a competing endogenous RNA in myogenesis PMCID:    Pubmed No.:25868726 CSF-1R regulates non-small cell lung cancer cells dissemination through Wnt3a signaling PMCID:    Pubmed No.:29218239 Succinate/NLRP3 Inflammasome Induces Synovial Fibroblast Activation: Therapeutical Effects of Clematichinenoside AR on Arthritis PMCID:    Pubmed No.:28003810 MnTBAP Therapy Attenuates Renal Fibrosis in Mice with 5/6 Nephrectomy PMCID:    Pubmed No.:26989454 HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation PMCID:    Pubmed No.:27110324 An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases PMCID:    Pubmed No.:26456587 Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction PMCID:    Pubmed No.:26196303 Low Dose of Bisphenol A Activates NF-κB/IL-6 Signals to Increase Malignancy of Neuroblastoma Cells PMCID:    Pubmed No.:27866306 Inhibition of Autophagy is Involved in the Protective Effects of Ginsenoside Rb1 on Spinal Cord Injury PMCID:    Pubmed No.:28762191 Fungal metabolite myriocin promotes human herpes simplex virus-2 infection PMCID:    Pubmed No.:25447452 Dermokine contributes to epithelial–mesenchymal transition through increased activation of signal transducer and activator of transcription 3 in pancreatic cancer PMCID:    Pubmed No.:28795470 Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy PMCID:    Pubmed No.:27381943 Alternation of adriamycin penetration kinetics in MCF-7 cells from 2D to 3D culture based on P-gp expression through the Chk2/p53/NF-κB pathway PMCID:    Pubmed No.:25478729 Surface topography of hydroxyapatite promotes osteogenic differentiation of human bone marrow mesenchymal stem cells PMCID:    Pubmed No.:26706505 Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons PMCID:    Pubmed No.:26363976 Casein Kinase II Controls TBK1/IRF3 Activation in IFN Response against Viral Infection PMCID:    Pubmed No.:25810395 Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids attenuates K/BxN serum-transfer arthritis in fat-1 mice PMCID:    Pubmed No.:25910895 EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway PMCID:    Pubmed No.:26539255 Exercise Combined with Rhodiola sacra Supplementation Improves Exercise Capacity and Ameliorates Exhaustive Exercise-Induced Muscle Damage through Enhancement of Mitochondrial Quality Control PMCID:    Pubmed No.:29359009 Tris (2-chloroethyl) phosphate induces senescence-like phenotype of hepatocytes via the p21Waf1/Cip1-Rb pathway in a p53-independent manner PMCID:    Pubmed No.:28886428 The saponin DT-13 Attenuates Tumor Necrosis Factor-α-induced Vascular Inflammation Associated with Src/NF-кB/MAPK Pathway Modulation PMCID:    Pubmed No.:26157351 A dioxidovanadium (V) complex of NNO-donor Schiff base as a selective inhibitor of protein tyrosine phosphatase 1B: Synthesis, characterization, and biological activities PMCID:    Pubmed No.:28199951 Xanthatin anti-tumor cytotoxicity is mediated via glycogen synthase kinase-3β and β-catenin PMCID:    Pubmed No.:27321043 rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway PMCID:    Pubmed No.:28038913 Microcystin-LR promotes migration and invasion of colorectal cancer through matrix metalloproteinase-13 up-regulation PMCID:    Pubmed No.:25789966 Lactoferrin promotes MC3T3-E1 osteoblast cells proliferation via MAPK signaling pathways PMCID:    Pubmed No.:28863893 Establishment of MAGEC2‐knockout cells and functional investigation of MAGEC2 in tumor cells PMCID:    Pubmed No.:27636589 Inducible ATF3–NFAT axis aggravates podocyte injury PMCID:    Pubmed No.:29038896 Therapeutic inhibition of SGK1 suppresses colorectal cancer PMCID:    Pubmed No.:29170478 Berberine ameliorates collagen‐induced arthritis in rats by suppressing Th17 cell responses via inducing cortistatin in the gut PMCID:    Pubmed No.:28636167 MiR-106b-mediated Mfn2 suppression is critical for PKM2 induced mitochondrial fusion PMCID:    Pubmed No.:27822413 Maresin 1 Mitigates High Glucose-Induced Mouse Glomerular Mesangial Cell Injury by Inhibiting Inflammation and Fibrosis PMCID:    Pubmed No.:28182085 Upregulation of mitogen-inducible gene 6 triggers antitumor effect and attenuates progesterone resistance in endometrial carcinoma cells PMCID:    Pubmed No.:26450625 Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice PMCID:    Pubmed No.:25956868 Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice PMCID:    Pubmed No.:25846502 Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and prevents insulin resistance in the endothelium PMCID:    Pubmed No.:30666402 PAC1R agonist maxadilan enhances hADSC viability and neural differentiation potential PMCID:    Pubmed No.:26798992 Sulindac has strong antifibrotic effects by suppressing STAT3‐related miR‐21 PMCID:    Pubmed No.:25704671 Quercetin oppositely regulates insulin‐mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation PMCID:    Pubmed No.:26627467 Alteration of Cholinergic Anti‐Inflammatory Pathway in Rat With Ischemic Cardiomyopathy–Modified Electrophysiological Function of Heart PMCID:    Pubmed No.:28928157 The Pivotal Role of Ca2+ Homeostasis in PBDE-47-Induced Neuronal Apoptosis PMCID:    Pubmed No.:26676572 Corilagin Attenuates Radiation-Induced Brain Injury in Mice PMCID:    Pubmed No.:26666668 Single injection of a novel nerve growth factor coacervate improves structural and functional regeneration after sciatic nerve injury in adult rats PMCID:    Pubmed No.:27983992 MiR-451 suppresses proliferation, migration and promotes apoptosis of the human osteosarcoma by targeting macrophage migration inhibitory factor PMCID:    Pubmed No.:28086136 mPGES-1-derived prostaglandin E2 stimulates Stat3 to promote podocyte apoptosis PMCID:    Pubmed No.:28879567 A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25–35-impaired mouse cognitive function PMCID:    Pubmed No.:26349994 Alpha‐Lipoic Acid Promotes Osteoblastic Formation in H2O2‐Treated MC3T3‐E1 Cells and Prevents Bone Loss in Ovariectomized Rats PMCID:    Pubmed No.:25655087 Respiratory Syncytial Virus Infection Upregulates NLRC5 and Major Histocompatibility Complex Class I Expression through RIG-I Induction in Airway Epithelial Cells PMCID:    Pubmed No.:25972545 P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions PMCID:    Pubmed No.:26136569 Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus PMCID:    Pubmed No.:27660267 Activation of Wnt/β‐catenin signalling is required for TGF‐β/Smad2/3 signalling during myofibroblast proliferation PMCID:    Pubmed No.:28244647 Cardiac cell proliferation is not necessary for exercise‐induced cardiac growth but required for its protection against ischaemia/reperfusion injury PMCID:    Pubmed No.:28304151 Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice PMCID:    Pubmed No.:27317762 Targeted inhibition of HDAC8 increases the doxorubicin sensitivity of neuroblastoma cells via up regulation of miR-137 PMCID:    Pubmed No.:28223126 Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain PMCID:    Pubmed No.:28669900 Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice PMCID:    Pubmed No.:28925407 Phosphatidic acid induces decidualization by stimulating Akt‐PP2A binding in human endometrial stromal cells PMCID:    Pubmed No.:27696687 FSTL1 as a Potential Mediator of Exercise-Induced Cardioprotection in Post-Myocardial Infarction Rats PMCID:    Pubmed No.:27561749 Renal Denervation Findings on Cardiac and Renal Fibrosis in Rats with Isoproterenol Induced Cardiomyopathy PMCID:    Pubmed No.:26689945 A recurrent deletion mutation in OPA1 causes autosomal dominant optic atrophy in a Chinese family PMCID:    Pubmed No.:25374051 MiR-200c regulates tumor growth and chemosensitivity to cisplatin in osteosarcoma by targeting AKT2 PMCID:    Pubmed No.:29051585 microRNA-124 targets glucocorticoid receptor and is involved in depression-like behaviors PMCID:    Pubmed No.:28764913 Geniposide attenuates ANIT-induced cholestasis through regulation of transporters and enzymes involved in bile acids homeostasis in rats PMCID:    Pubmed No.:27988401 αMSH promotes preadipocyte proliferation by alleviating ER stress-induced leptin resistance and by activating Notch1 signal in mice PMCID:    Pubmed No.:27717825 Mangiferin protects mitochondrial function by preserving mitochondrial hexokinase-II in vessel endothelial cells PMCID:    Pubmed No.:28478227 Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1 PMCID:    Pubmed No.:28736181 The effects of autophagy on vascular endothelial cells induced by airborne PM2.5 PMCID:    Pubmed No.:29628085 Corosolic acid inhibits adipose tissue inflammation and ameliorates insulin resistance via AMPK activation in high-fat fed mice PMCID:    Pubmed No.:26926180 Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms PMCID:    Pubmed No.:26960947 Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage PMCID:    Pubmed No.:28935668 iTRAQ protein profile analysis of neuroblastoma (NA) cells infected with the rabies viruses rHep-Flury and Hep-dG PMCID:    Pubmed No.:26217322 The Combination of Three Components Derived from Sheng MaiSan Protects Myocardial Ischemic Diseases and Inhibits Oxidative Stress via Modulating MAPKs and JAK2-STAT3 Signaling Pathways Based on Bioinformatics Approach PMCID:    Pubmed No.:28197101 Daily Suction Provided by External Volume Expansion Inducing Regeneration of Grafted Fat in a Murine Model PMCID:    Pubmed No.:28121866 Lipoxin A 4 activates alveolar epithelial sodium channel gamma via the microRNA-21/PTEN/AKT pathway in lipopolysaccharide-induced inflammatory lung injury PMCID:    Pubmed No.:26302186 Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies PMCID:    Pubmed No.:26978516 Evaluation and Treatment of Endoplasmic Reticulum (ER) Stress in Right Ventricular Dysfunction during Monocrotaline-Induced Rat Pulmonary Arterial Hypertension PMCID:    Pubmed No.:27844183 Partial inhibition of activin receptor-like kinase 4 attenuates pressure overload-induced cardiac fibrosis and improves cardiac function PMCID:    Pubmed No.:27379535 Comparative proteomic analysis of the effects of high-concentrate diet on the hepatic metabolism and inflammatory response in lactating dairy goats PMCID:    Pubmed No.:26855776 The important role of the receptor for activated C kinase 1 (RACK1) in nasopharyngeal carcinoma progression PMCID:    Pubmed No.:27170279 Curcumin alleviated the toxic reaction of Rhizoma Paridis saponins in a 45-day subchronic toxicological assessment of rats PMCID:    Pubmed No.:26390842 Enhanced HOXA10 sumoylation inhibits embryo implantation in women with recurrent implantation failure PMCID:    Pubmed No.:29018572 Elimination of GPR146‐mediated antiviral function through IRF3/HES1‐signalling pathway PMCID:    Pubmed No.:28464285 Interleukin‐17 regulates the expressions of RANKL and OPG in human periodontal ligament cells via TRAF6/TBK1‐JNK/NF‐κB pathways PMCID:    Pubmed No.:25263088 Three novel missense mutations in the filamin B gene are associated with isolated congenital talipes equinovarus PMCID:    Pubmed No.:27395407 The chromatin remodeler Chd4 maintains embryonic stem cell identity by controlling pluripotency- and differentiation-associated genes PMCID:    Pubmed No.:28298436 Aqueous extract of pomegranate seed attenuates glucocorticoid-induced bone loss and hypercalciuria in mice: A comparative study with alendronate PMCID:    Pubmed No.:27278225 Reg3α Overexpression Protects Pancreatic β Cells from Cytokine-Induced Damage and Improves Islet Transplant Outcome PMCID:    Pubmed No.:25826674 Aspirin Inhibits LPS-Induced Expression of PI3K/Akt, ERK, NF-κB, CX3CL1, and MMPs in Human Bronchial Epithelial Cells PMCID:    Pubmed No.:26635114 Triterpenoids‐Enriched Extract from the Aerial Parts of Salvia miltiorrhiza Regulates Macrophage Polarization and Ameliorates Insulin Resistance in High‐Fat Fed Mice PMCID:    Pubmed No.:27714922 Antidepressant-like effect of zileuton is accompanied by hippocampal neuroinflammation reduction and CREB/BDNF upregulation in lipopolysaccharide-challenged mice PMCID:    Pubmed No.:29174741 Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxidative Injury through ERK1/2 Signaling Pathway PMCID:    Pubmed No.:27994507 Dual Delivery of NGF and bFGF Coacervater Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Schwann Cells Apoptosis PMCID:    Pubmed No.:28539836 Salvianolic acids enhance cerebral angiogenesis and neurological recovery by activating JAK2/STAT3 signaling pathway after ischemic stroke in mice PMCID:    Pubmed No.:28771727 Effects of microRNA-29a on retinopathy of prematurity by targeting AGT in a mouse model PMCID:    Pubmed No.:28337307 Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3 PMCID:    Pubmed No.:26818531 Effect of bovine lactoferrin and human lactoferrin on the proliferative activity of the osteoblast cell line MC3T3-E1 in vitro PMCID:    Pubmed No.:29290425 Demethyleneberberine, a Natural Mitochondria-Targeted Antioxidant, Inhibits Mitochondrial Dysfunction, Oxidative Stress, and Steatosis in Alcoholic Liver Disease Mouse Model PMCID:    Pubmed No.:25362106 The enhanced atorvastatin hepatotoxicity in diabetic rats was partly attributed to the upregulated hepatic Cyp3a and SLCO1B1 PMCID:    Pubmed No.:27624558 Effects of chronic noise on glucose metabolism and gut microbiota–host inflammatory homeostasis in rats PMCID:    Pubmed No.:27811997 MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway PMCID:    Pubmed No.:28165066 Identification of Novel MAGE-G1-Interacting Partners in Retinoic Acid-Induced P19 Neuronal Differentiation Using SILAC-Based Proteomics PMCID:    Pubmed No.:28374796 The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways PMCID:    Pubmed No.:28611356 PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells PMCID:    Pubmed No.:26860588 The Role of Na+/Ca2+ Exchanger 1 in Maintaining Ductus Arteriosus Patency PMCID:    Pubmed No.:28852106 HSPA12B Attenuated Acute Myocardial Ischemia/reperfusion Injury via Maintaining Endothelial Integrity in a PI3K/Akt/mTOR-dependent Mechanism PMCID:    Pubmed No.:27644317 Prophylaxis of Diallyl Disulfide on Skin Carcinogenic Model via p21-dependent Nrf2 stabilization PMCID:    Pubmed No.:27759091 α-MSH and Foxc2 promote fatty acid oxidation through C/EBPβ negative transcription in mice adipose tissue PMCID:    Pubmed No.:27819350 Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3 PMCID:    Pubmed No.:28484278 Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia PMCID:    Pubmed No.:28500304 Effects of dietary methionine on breast muscle growth, myogenic gene expression and IGF-I signaling in fast- and slow-growing broilers PMCID:    Pubmed No.:28507342 Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity PMCID:    Pubmed No.:28588300 Oncolytic measles virus enhances antitumour responses of adoptive CD8 + NKG2D + cells in hepatocellular carcinoma treatment PMCID:    Pubmed No.:28701757 Galangin attenuates airway remodelling by inhibiting TGF-β1-mediated ROS generation and MAPK/Akt phosphorylation in asthma PMCID:    Pubmed No.:26156213 Remarkable plasticity of Na + , K + -ATPase, Ca 2+ -ATPase and SERCA contributes to muscle disuse atrophy resistance in hibernating Daurian ground squirrels PMCID:    Pubmed No.:28874726 Detrimental effect of Hypoxia-inducible factor-1α-induced autophagy on multiterritory perforator flap survival in rats PMCID:    Pubmed No.:28924179 Non-classical MHC I-E negatively regulates macrophage activation and Th17 cell development in NOD mice PMCID:    Pubmed No.:26251280 FOXA2 alleviates CCl 4 -induced liver fibrosis by protecting hepatocytes in mice PMCID:    Pubmed No.:15532 (2017) MiR-30e inhibits tumor growth and chemoresistance via targeting IRS1 in Breast Cancer PMCID:    Pubmed No.:29162879 RNA Interference Silencing of Glycogen Synthase Kinase 3β Inhibites Tau Phosphorylation in Mice with Alzheimer Disease PMCID:    Pubmed No.:27255602 NGF Attenuates High Glucose-Induced ER Stress, Preventing Schwann Cell Apoptosis by Activating the PI3K/Akt/GSK3β and ERK1/2 Pathways PMCID:    Pubmed No.:28762104 Esculentoside A exerts anti-inflammatory activity in microglial cells PMCID:    Pubmed No.:28843178 Autophagy regulates intracerebral hemorrhage induced neural damage via apoptosis and NF-κB pathway PMCID:    Pubmed No.:26964766 FKBP5 and specific microRNAs via glucocorticoid receptor in the basolateral amygdala involved in the susceptibility to depressive disorder in early adolescent stressed rats PMCID:    Pubmed No.:28826069 Cripto-1 promotes epithelial-mesenchymal transition in prostate cancer via Wnt/β-catenin signaling PMCID:    Pubmed No.:28098905 Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction PMCID:    Pubmed No.:26074971 Benzo[a]pyrene promotes gastric cancer cell proliferation and metastasis likely through the Aryl hydrocarbon receptor and ERK-dependent induction of MMP9 and c-myc PMCID:    Pubmed No.:27601158 Prognostic value of pigment epithelium-derived factor for neoadjuvant radiation therapy in patients with locally advanced rectal carcinoma PMCID:    Pubmed No.:27431441 MicroRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer PMCID:    Pubmed No.:26983891 The tumor suppressor miR-124 inhibits cell proliferation by targeting STAT3 and functions as a prognostic marker for postoperative NSCLC patients PMCID:    Pubmed No.:25531908 Effects of macrophage migration inhibitory factor on cardiac reperfusion injury in mice with depression induced by constant-darkness PMCID:    Pubmed No.:29331700 Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice PMCID:    Pubmed No.:26527380 Iron Together with Lipid Downregulates Protein Levels of Ceruloplasmin in Macrophages Associated with Rapid Foam Cell Formation PMCID:    Pubmed No.:27040361 Different Angiogenic Potentials of Mesenchymal Stem Cells Derived from Umbilical Artery, Umbilical Vein, and Wharton’s Jelly PMCID:    Pubmed No.:28874910 Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance PMCID:    Pubmed No.:28261091 Oroxyloside A Overcomes Bone Marrow Microenvironment-Mediated Chronic Myelogenous Leukemia Resistance to Imatinib via Suppressing Hedgehog Pathway PMCID:    Pubmed No.:28848440 Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes PMCID:    Pubmed No.:29234281 Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF‐1α synthesis, and decreases breast cancer metastasis PMCID:    Pubmed No.:28574600 Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK PMCID:    Pubmed No.:26277096 Human Umbilical Cord Mesenchymal Stem Cells Protect Against SCA3 by Modulating the Level of 70 kD Heat Shock Protein PMCID:    Pubmed No.:28667374 Role of 5‐HT1A receptor in insular cortex mediating stress – induced visceral sensory dysfunction PMCID:    Pubmed No.:26969829 Hypoxia-induced and HIF1α-VEGF-mediated tight junction dysfunction in choriocarcinoma cells: Implications for preeclampsia PMCID:    Pubmed No.:29223764 Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis PMCID:    Pubmed No.:28689917 Effects of Curcumin on Tobacco Smoke‐induced Hepatic MAPK Pathway Activation and Epithelial–Mesenchymal Transition In Vivo PMCID:    Pubmed No.:28585748 Curcumin Suppresses MAPK Pathways to Reverse Tobacco Smoke‐induced Gastric Epithelial–Mesenchymal Transition in Mice PMCID:    Pubmed No.:26074474 Cigarette smoke extract induces epithelial–mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway PMCID:    Pubmed No.:28012925 Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway PMCID:    Pubmed No.:29136772 Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells PMCID:    Pubmed No.:29793316 Activation of Epac alleviates inflammation and vascular leakage in LPS-induced acute murine lung injury PMCID:    Pubmed No.:29174852 Roles of Pannexin-1 Channels in Inflammatory Response through the TLRs/NF-Kappa B Signaling Pathway Following Experimental Subarachnoid Hemorrhage in Rats PMCID:    Pubmed No.:28634441 LPS-induced CXCR4-dependent migratory properties and a mesenchymal-like phenotype of colorectal cancer cells PMCID:    Pubmed No.:26745593 Metformin and resveratrol inhibit Drp1-mediated mitochondrial fission and prevent ER stress-associated NLRP3 inflammasome activation in the adipose tissue of diabetic mice PMCID:    Pubmed No.:27276511 Esculentoside A suppresses lipopolysaccharide-induced pro-inflammatory molecule production partially by casein kinase 2 PMCID:    Pubmed No.:28027904 YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-κB and ROCK1/MLC signaling pathways PMCID:    Pubmed No.:26915982 Huangkui capsule attenuates renal fibrosis in diabetic nephropathy rats through regulating oxidative stress and p38MAPK/Akt pathways, compared to α-lipoic acid PMCID:    Pubmed No.:26226437 D-chiro-inositol enriched Fagopyrum tataricum (L.) Gaench extract alleviates mitochondrial malfunction and inhibits ER stress/JNK associated inflammation in the endothelium PMCID:    Pubmed No.:29225119 Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer’s disease-like tau hyperphosphorylation PMCID:    Pubmed No.:29228900 Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells PMCID:    Pubmed No.:27239113 Diosmetin prevents TGF-β1-induced epithelial-mesenchymal transition via ROS/MAPK signaling pathways PMCID:    Pubmed No.:27101925 Interval exercise training increases LIF expression and prevents myocardial infarction-induced skeletal muscle atrophy in rats PMCID:    Pubmed No.:29223542 Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF‐9/MAPK/Smad pathway PMCID:    Pubmed No.:28346732 miR-451 inhibits cell growth, migration and angiogenesis in human osteosarcoma via down-regulating IL 6R PMCID:    Pubmed No.:27908732 Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress PMCID:    Pubmed No.:26970305 The NLRP3 inflammasome is dispensable for ER stress-induced pancreatic β-cell damage in Akita mice PMCID:    Pubmed No.:26361146 Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission PMCID:    Pubmed No.:27960279 Curcumin reverses benzidine-induced epithelial-mesenchymal transition via suppression of ERK5/AP-1 in SV-40 immortalized human urothelial cells PMCID:    Pubmed No.:28259934 Restoration of KLF4 Inhibits Invasion and Metastases of Lung Adenocarcinoma through Suppressing MMP2 PMCID:    Pubmed No.:29151932 High-Mobility Group Box 1 Mediates Epithelial-to-Mesenchymal Transition in Pulmonary Fibrosis Involving Transforming Growth Factor-β1/Smad2/3 Signaling PMCID:    Pubmed No.:26126535 Persistent Exposure to Porphyromonas gingivalis Promotes Proliferative and Invasion Capabilities, and Tumorigenic Properties of Human Immortalized Oral Epithelial Cells PMCID:    Pubmed No.:28286742 PSD-93 Attenuates Amyloid-β-Mediated Cognitive Dysfunction by Promoting the Catabolism of Amyloid-β PMCID:    Pubmed No.:28697571 Salvia miltiorrhiza Lipophilic Fraction Attenuates Oxidative Stress in Diabetic Nephropathy through Activation of Nuclear Factor Erythroid 2-Related Factor 2 PMCID:    Pubmed No.:28946766 Curcumin attenuates BPA-induced insulin resistance in HepG2 cells through suppression of JNK/p38 pathways PMCID:    Pubmed No.:28300666 BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro PMCID:    Pubmed No.:26024915 Autophagy can alleviate severe burn-induced damage to the intestinal tract in mice PMCID:    Pubmed No.:28624177 Urocortin Attenuates TGFβ1‐Induced Snail1 and Slug Expressions: Inhibitory Role of Smad7 in Smad2/3 Signaling in Breast Cancer Cells PMCID:    Pubmed No.:26138318 The effect of tetrandrine combined with cisplatin on proliferation and apoptosis of A549/DDP cells and A549 cells PMCID:    Pubmed No.:28360820 Differential drug resistance acquisition to doxorubicin and paclitaxel in breast cancer cells PMCID:    Pubmed No.:25550688 miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1 PMCID:    Pubmed No.:28260112 Asporin participates in gastric cancer cell growth and migration by influencing EGF receptor signaling PMCID:    Pubmed No.:25673058 Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4 PMCID:    Pubmed No.:29048629 Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium PMCID:    Pubmed No.:25922268 The anti-tumour activity of rLj-RGD4, an RGD toxin protein from Lampetra japonica, on human laryngeal squamous carcinoma Hep-2 cells in nude mice PMCID:    Pubmed No.:26549486 Oroxylin A reverses the drug resistance of chronic myelogenous leukemia cells to imatinib through CXCL12/CXCR7 axis in bone marrow microenvironment PMCID:    Pubmed No.:27533597 Functional role and mechanism of lncRNA LOC728228 in malignant 16HBE cells transformed by anti‐benzopyrene‐trans‐7,8‐dihydrodiol‐9,10‐epoxide PMCID:    Pubmed No.:25820656 miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation PMCID:    Pubmed No.:28844858 Phosphorylated heat shock protein 27 promotes lipid clearance in hepatic cells through interacting with STAT3 and activating autophagy PMCID:    Pubmed No.:27185187 FOXQ1 promotes cancer metastasis by PI3K/AKT signaling regulation in colorectal carcinoma PMCID:    Pubmed No.:28559972 Silencing of advanced glycosylation and glycosylation and product-specific receptor (RAGE) inhibits the metastasis and growth of non-small cell lung cancer PMCID:    Pubmed No.:28670367 Characterization of aromatase expression in the spinal cord of an animal model of familial ALS PMCID:    Pubmed No.:28583855 Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats PMCID:    Pubmed No.:25839444 Role of microRNA-29a in the development of diabetic retinopathy by targeting AGT gene in a rat model PMCID:    Pubmed No.:28189547 Treatment with NAD+ inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice PMCID:    Pubmed No.:27500459 Ampelopsin attenuates lipopolysaccharide-induced inflammatory response through the inhibition of the NF-κB and JAK2/STAT3 signaling pathways in microglia PMCID:    Pubmed No.:27998743 The correlation between inflammatory injury induced by LPS and RAS in EpH4-Ev cells PMCID:    Pubmed No.:28249221 Resokaempferol-mediated anti-inflammatory effects on activated macrophages via the inhibition of JAK2/STAT3, NF-κB and JNK/p38 MAPK signaling pathways PMCID:    Pubmed No.:27261558 Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide PMCID:    Pubmed No.:27289299 Induction of forkhead box M1 (FoxM1) by EGF through ERK signaling pathway promotes trophoblast cell invasion PMCID:    Pubmed No.:26022336 Mechanism-Based Inhibitory and Peroxisome Proliferator-Activated Receptor α–Dependent Modulating Effects of Silybin on Principal Hepatic Drug-Metabolizing Enzymes PMCID:    Pubmed No.:25587127 Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity PMCID:    Pubmed No.:27832326 Assessment of mouse cognitive and anxiety-like behaviors and hippocampal inflammation following a repeated and intermittent paradoxical sleep deprivation procedure PMCID:    Pubmed No.:28043900 A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells PMCID:    Pubmed No.:28038917 Iptakalim inhibits PDGF-BB-induced human airway smooth muscle cells proliferation and migration PMCID:    Pubmed No.:26160451 DDAH1-V3 transcript might act as miR-21 sponge to maintain balance of DDAH1-V1 in cultured HUVECs PMCID:    Pubmed No.:27663503 Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells PMCID:    Pubmed No.:26204324 Glutathione-s-transferase A 4 (GSTA4) suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting AKT pathway PMCID:    Pubmed No.:28337261 Interleukin-25 enhances the capacity of mesenchymal stem cells to induce intestinal epithelial cell regeneration PMCID:    Pubmed No.:29312486 Ameliorating effects of 1,8-cineole on LPS-induced human umbilical vein endothelial cell injury by suppressing NF-κB signaling in vitro PMCID:    Pubmed No.:27455900 Inhibition of lipolysis by ilexgenin A via AMPK activation contributes to the prevention of hepatic insulin resistance PMCID:    Pubmed No.:28739087 Hinokitiol copper complex inhibits proteasomal deubiquitination and induces paraptosis-like cell death in human cancer cells PMCID:    Pubmed No.:28887042 Caruifolin D from artemisia absinthium L. inhibits neuroinflammation via reactive oxygen species-dependent c-jun N-terminal kinase and protein kinase c/NF-κB signaling pathways PMCID:    Pubmed No.:26455476 Inhibition of thioredoxin-1 with siRNA exacerbates apoptosis by activating the ASK1-JNK/p38 pathway in brain of a stroke model rats PMCID:    Pubmed No.:25541364 LRG1 suppresses the migration and invasion of hepatocellular carcinoma cells PMCID:    Pubmed No.:25814288 Role of Autophagy in Angiogenesis Induced by a High-Glucose Condition in RF/6A Cells PMCID:    Pubmed No.:28253511 Paeonol inhibits B16F10 melanoma metastasis In vitro and In Vivo via disrupting proinflammatory cytokines‐mediated NF‐κB and STAT3 pathways PMCID:    Pubmed No.:26452780 mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines PMCID:    Pubmed No.:26122641 Changes in milk performance and hepatic metabolism in mid-lactating dairy goats after being fed a high concentrate diet for 10 weeks PMCID:    Pubmed No.:27506262 IL-25 Promotes Th2 Immunity Responses in Asthmatic Mice via Nuocytes Activation PMCID:    Pubmed No.:27617447 The Effects of Auricular Electro-Acupuncture on Ameliorating the Dysfunction of Interstitial Cells of Cajal Networks and nNOSmRNA Expression in Antrum of STZ-Induced Diabetic Rats PMCID:    Pubmed No.:27930657 Expression of heat shock protein 70 in transport-stressed broiler pectoralis major muscle and its relationship with meat quality PMCID:    Pubmed No.:28077200 A Novel Missense Mutation of GATA4 in a Chinese Family with Congenital Heart Disease PMCID:    Pubmed No.:27391137 Therapeutic Effects of Bupleurum Polysaccharides in Streptozotocin Induced Diabetic Mice PMCID:    Pubmed No.:26176625 Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells PMCID:    Pubmed No.:26382838 Protective effects of paeonol on inflammatory response in IL-1β-induced human fibroblast-like synoviocytes and rheumatoid arthritis progression via modulating NF-κB pathway PMCID:    Pubmed No.:28799079 Increased Krüppel-like factor 12 in recurrent implantation failure impairs endometrial decidualization by repressing Nur77 expression PMCID:    Pubmed No.:28359310 Krüppel-like factor 12 is a novel negative regulator of forkhead box O1 expression: a potential role in impaired decidualization PMCID:    Pubmed No.:26223982 NEB-related core-rod myopathy with distinct clinical and pathological features PMCID:    Pubmed No.:26562614 Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway PMCID:    Pubmed No.:26316699 Interaction Between Gastric Carcinoma Cells and Neural Cells Promotes Perineural Invasion by a Pathway Involving VCAM1 PMCID:    Pubmed No.:26108418 Naringin prevents carbon tetrachloride-induced acute liver injury in mice PMCID:    Pubmed No.:36559593 miR-134 Functions as a Tumor Suppressor in Cell Proliferation and Epithelial-to-Mesenchymal Transition by Targeting KRAS in Renal Cell Carcinoma Cells PMCID:    Pubmed No.:25811077 Heparanase Contributes To Trans-Endothelial Migration of Hepatocellular Carcinoma Cells PMCID:    Pubmed No.:29158804 Curcumin inhibits placental inflammation to ameliorate LPS-induced adverse pregnancy outcomes in mice via upregulation of phosphorylated Akt PMCID:    Pubmed No.:27817102 Insights into anticancer activity and mechanism of action of a ruthenium(II) complex in human esophageal squamous carcinoma EC109 cells PMCID:    Pubmed No.:27262377 MiR-130b plays an oncogenic role by repressing PTEN expression in esophageal squamous cell carcinoma cells PMCID:    Pubmed No.:25637514 MicroRNA-33a and let-7e inhibit human colorectal cancer progression by targeting ST8SIA1 PMCID:    Pubmed No.:28751193 MiR-26a and miR-26b mediate osteoarthritis progression by targeting FUT4 via NF-κB signaling pathway PMCID:    Pubmed No.:29208566 Combined effect of tris(2-chloroethyl)phosphate and benzo (a) pyrene on the release of IL-6 and IL-8 from HepG2 cells via the EGFR-ERK1/2 signaling pathway PMCID:    Pubmed No.:33233533 l-Theanine attenuates cadmium-induced neurotoxicity through the inhibition of oxidative damage and tau hyperphosphorylation PMCID:    Pubmed No.:27649883 Targeting Gene-Virus-Mediated Manganese Superoxide Dismutase Effectively Suppresses Tumor Growth in Hepatocellular Carcinoma In Vitro and In Vivo PMCID:    Pubmed No.:25414976 Multi-glycoside of Tripterygium wilfordii Hook. f. attenuates glomerulosclerosis in a rat model of diabetic nephropathy by exerting anti-microinflammatory effects without affecting hyperglycemia PMCID:    Pubmed No.:28731135 MicroRNA-218 inhibits the proliferation and metastasis of esophageal squamous cell carcinoma cells by targeting BMI1 PMCID:    Pubmed No.:25999024 Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice PMCID:    Pubmed No.:29115561 Proteomic Analysis of HDAC3 Selective Inhibitor in the Regulation of Inflammatory Response of Primary Microglia PMCID:    Pubmed No.:28293439 Manipulation of necroptosis by Porphyromonas gingivalis in periodontitis development PMCID:    Pubmed No.:27449906 Daphnetin reduces endotoxin lethality in mice and decreases LPS-induced inflammation in Raw264.7 cells via suppressing JAK/STATs activation and ROS production PMCID:    Pubmed No.:28409189 Inhibition of diethylnitrosamine-induced liver cancer in rats by Rhizoma paridis saponin PMCID:    Pubmed No.:27451357 Endometrial Receptivity Markers in Mice Stimulated With Raloxifene Versus Clomiphene Citrate and Natural Cycles PMCID:    Pubmed No.:26603317 MLF1IP promotes normal erythroid proliferation and is involved in the pathogenesis of polycythemia vera PMCID:    Pubmed No.:28173615 Changes in astrocyte functional markers and β-amyloid metabolism-related proteins in the early stages of hypercholesterolemia PMCID:    Pubmed No.:26724580 MicroRNA‐106b targets FUT6 to promote cell migration, invasion, and proliferation in human breast cancer PMCID:    Pubmed No.:27519168 Cysteine‐rich buccal gland protein suppressed the proliferation, migration and invasion of hela cells through akt pathway PMCID:    Pubmed No.:28945311 Mild hypothermia protects rat neuronal injury after intracerebral hemorrhage via attenuating endoplasmic reticulum response induced neuron apoptosis PMCID:    Pubmed No.:27771296 Long noncoding RNA NBAT-1 suppresses tumorigenesis and predicts favorable prognosis in ovarian cancer PMCID:    Pubmed No.:28435289 miR-125b inhibited epithelial–mesenchymal transition of triple-negative breast cancer by targeting MAP2K7 PMCID:    Pubmed No.:27226726 Transcriptional silencing of ETS-1 abrogates epithelial-mesenchymal transition resulting in reduced motility of pancreatic cancer cells PMCID:    Pubmed No.:25421630 ERK5 positively regulates cigarette smoke-induced urocystic epithelial-mesenchymal transition in SV‑40 immortalized human urothelial cells PMCID:    Pubmed No.:26177962 Knockdown of c‑Myc activates Fas-mediated apoptosis and sensitizes A549 cells to radiation PMCID:    Pubmed No.:28849062 SLC7A11, a component of cysteine/glutamate transporter, is a novel biomarker for the diagnosis and prognosis in laryngeal squamous cell carcinoma PMCID:    Pubmed No.:29048627 Protective Effect of l -Theanine on Cadmium-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondria-Mediated Pathway PMCID:    Pubmed No.:26164708 The role of Ca2+ mediated signaling pathways on the effect of taurine against Streptococcus uberis infection PMCID:    Pubmed No.:27527761 Modified Si-Miao-San inhibits inflammation and promotes glucose disposal in adipocytes through regulation of AMP-kinase PMCID:    Pubmed No.:25556062 Matrigel and Activin A promote cell-cell contact and anti-apoptotic activity in cultured human retinal pigment epithelium cells PMCID:    Pubmed No.:27130547 Tris(2‐chloroethyl)phosphate‐induced cell growth arrest via attenuation of SIRT1‐independent PI3K/Akt/mTOR pathway PMCID:    Pubmed No.:26378621 Ubiquitin-specific protease 14 regulates cardiac hypertrophy progression by increasing GSK-3β phosphorylation PMCID:    Pubmed No.:27545607 Bapx1 mediates transforming growth factor-β- induced epithelial-mesenchymal transition and promotes a malignancy phenotype of gastric cancer cells PMCID:    Pubmed No.:28315334 Crosstalk between JNK and NF-κB signaling pathways via HSP27 phosphorylation in HepG2 cells PMCID:    Pubmed No.:25446109 DT-13 ameliorates TNF-α-induced nitric oxide production in the endothelium in vivo and in vitro PMCID:    Pubmed No.:29162452 TPX2 promotes glioma cell proliferation and invasion via activation of the AKT signaling pathway PMCID:    Pubmed No.:28105208 All-trans retinoic acid inhibits migration, invasion and proliferation, and promotes apoptosis in glioma cells in vitro PMCID:    Pubmed No.:26137156 miR-93 enhances cell proliferation by directly targeting CDKN1A in nasopharyngeal carcinoma PMCID:    Pubmed No.:29434867 The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells PMCID:    Pubmed No.:25695094 A novel missense mutation in the ALPL gene causes dysfunction of the protein PMCID:    Pubmed No.:28586049 AQP3 small interfering RNA and PLD2 small interfering RNA inhibit the proliferation and promote the apoptosis of squamous cell carcinoma PMCID:    Pubmed No.:28656282 Serum amyloid A stimulates vascular endothelial growth factor receptor 2 expression and angiogenesis PMCID:    Pubmed No.:26714823 Cadmium pyrithione suppresses tumor growth in vitro and in vivo through inhibition of proteasomal deubiquitinase PMCID:    Pubmed No.:29098502 Clostridium butyricum exerts a neuroprotective effect in a mouse model of traumatic brain injury via the gut‐brain axis PMCID:    Pubmed No.:29193450 Anti-inflammatory Activity of Magnesium Isoglycyrrhizinate Through Inhibition of Phospholipase A2/Arachidonic Acid Pathway PMCID:    Pubmed No.:25691139 Involvement of Prokineticin 2 and Prokineticin Receptor 1 in Lipopolysaccharide-Induced Testitis in Rats PMCID:    Pubmed No.:26490969 MicroRNA-370 Attenuates Hepatic Fibrogenesis by Targeting Smoothened PMCID:    Pubmed No.:25686745 miR-182 and miR-135b Mediate the Tumorigenesis and Invasiveness of Colorectal Cancer Cells via Targeting ST6GALNAC2 and PI3K/AKT Pathway PMCID:    Pubmed No.:29030743 Effects of miRNA-455 on cardiac hypertrophy induced by pressure overload PMCID:    Pubmed No.:25695617 Vaspin protects against LPS‑induced ARDS by inhibiting inflammation, apoptosis and reactive oxygen species generation in pulmonary endothelial cells via the Akt/GSK‑3β pathway PMCID:    Pubmed No.:29039444 MiR-1224-5p acts as a tumor suppressor by targeting CREB1 in malignant gliomas PMCID:    Pubmed No.:25648114 GalNAc-T4 putatively modulates the estrogen regulatory network through FOXA1 glycosylation in human breast cancer cells PMCID:    Pubmed No.:26541755 MiR-320a effectively suppresses lung adenocarcinoma cell proliferation and metastasis by regulating STAT3 signals PMCID:    Pubmed No.:28106481 Protective effect of Rabdosia amethystoides (Benth) Hara extract on acute liver injury induced by Concanavalin A in mice through inhibition of TLR4-NF-κB signaling pathway PMCID:    Pubmed No.:26823124 Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response PMCID:    Pubmed No.:27725120 Globular CTRP9 inhibits oxLDL-induced inflammatory response in RAW 264.7 macrophages via AMPK activation PMCID:    Pubmed No.:27188183 Long-term effects of early adolescent stress: dysregulation of hypothalamic–pituitary–adrenal axis and central corticotropin releasing factor receptor 1 expression in adult male rats PMCID:    Pubmed No.:25882722 Lithium chloride administration prevents spatial learning and memory impairment in repeated cerebral ischemia-reperfusion mice by depressing apoptosis and increasing BDNF expression in hippocampus PMCID:    Pubmed No.:26031381 Zeta Inhibitory Peptide as a Novel Therapy to Control Chronic Visceral Hypersensitivity in a Rat Model PMCID:    Pubmed No.:27776136 Overexpression of microRNA-99a Attenuates Cardiac Hypertrophy PMCID:    Pubmed No.:26914935 Regulation of PKM2 and Nrf2-ARE Pathway during Benzoquinone Induced Oxidative Stress in Yolk Sac Hematopoietic Stem Cells PMCID:    Pubmed No.:25437431 Chlorogenic Acid Improves Late Diabetes through Adiponectin Receptor Signaling Pathways in db/db Mice PMCID:    Pubmed No.:25849026 Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways PMCID:    Pubmed No.:25927362 Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells PMCID:    Pubmed No.:26114294 Human Urinary Kallidinogenase Promotes Angiogenesis and Cerebral Perfusion in Experimental Stroke PMCID:    Pubmed No.:26222055 Neuronal and Endothelial Nitric Oxide Synthases in the Paraventricular Nucleus Modulate Sympathetic Overdrive in Insulin-Resistant Rats PMCID:    Pubmed No.:26485682 Micheliolide suppresses LPS-induced neuroinflammatory responses PMCID:    Pubmed No.:29040306 Single Administration of Ultra-Low-Dose Lipopolysaccharide in Rat Early Pregnancy Induces TLR4 Activation in the Placenta Contributing to Preeclampsia PMCID:    Pubmed No.:25853857 Fractalkine/CX3CR1 is involved in the pathogenesis of endometriosis by regulating endometrial stromal cell proliferation and invasion PMCID:    Pubmed No.:27553970 Reduced protein expressions of cytomembrane GABAARβ3 at different postnatal developmental stages of rats exposed prenatally to valproic acid PMCID:    Pubmed No.:28641949 Microwave radiation leading to shrinkage of dendritic spines in hippocampal neurons mediated by SNK-SPAR pathway PMCID:    Pubmed No.:29180226 MiR-21 promotes fibrosis and hypertrophy of ligamentum flavum in lumbar spinal canal stenosis by activating IL-6 expression PMCID:    Pubmed No.:28669725 Suppressing Cyclooxygenase-2 Prevents nonalcoholic and inhibits apoptosis of hepatocytes that are involved in the Akt/p53 signal pathway PMCID:    Pubmed No.:26723251 miR-19 promotes osteosarcoma progression by targeting SOCS6 PMCID:    Pubmed No.:28986253 Coatomer subunit beta 2 (COPB2), identified by label-free quantitative proteomics, regulates cell proliferation and apoptosis in human prostate carcinoma cells PMCID:    Pubmed No.:29129687 P53 modulates hepatic insulin sensitivity through NF-κB and p38/ERK MAPK pathways PMCID:    Pubmed No.:29258820 Oral administration of propionic acid during lactation enhances the colonic barrier function PMCID:    Pubmed No.:28335773 Effects of chronic noise on mRNA and protein expression of CRF family molecules and its relationship with p-tau in the rat prefrontal cortex PMCID:    Pubmed No.:27538655 TRAF2 is a Valuable Prognostic Biomarker in Patients with Prostate Cancer PMCID:    Pubmed No.:28855498 Role of gelsolin in cell proliferation and invasion of human hepatocellular carcinoma cells PMCID:    Pubmed No.:26149653 Dahuang Fuzi Decoction Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in Chronic Aristolochic Acid Nephropathy PMCID:    Pubmed No.:28421124 Homoplantaginin Inhibits Palmitic Acid-induced Endothelial Cells Inflammation by Suppressing TLR4 and NLRP3 Inflammasome PMCID:    Pubmed No.:26355761 Cerebrospinal fluid-contacting nucleus mediates nociception via release of fractalkine PMCID:    Pubmed No.:28793053 Activating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro PMCID:    Pubmed No.:28577574 Blockade of LGR4 inhibits proliferation and odonto/osteogenic differentiation of stem cells from apical papillae PMCID:    Pubmed No.:28986711 Curdione attenuates thrombin-induced human platelet activation: β1-tubulin as a potential therapeutic target PMCID:    Pubmed No.:27915054 Lipopolysaccharide enhances OSCC migration by promoting epithelial–mesenchymal transition PMCID:    Pubmed No.:25367215 CART modulates beta-amyloid metabolism-associated enzymes and attenuates memory deficits in APP/PS1 mice PMCID:    Pubmed No.:28743230 PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats PMCID:    Pubmed No.:29113791 Development of hybrid-type modified chitosan derivative nanoparticles for the intracellular delivery of midkine-siRNA in hepatocellular carcinoma cells PMCID:    Pubmed No.:29467852 Association between mossy fiber sprouting and expression of semaphorin-3f protein in dentate gyrus of hippocampus in lithium-pilocarpine-induced status epilepticus mouse model PMCID:    Pubmed No.:27745527 Ulinastatin downregulates TLR4 and NF-kB expression and protects mouse brains against ischemia/reperfusion injury PMCID:    Pubmed No.:28191863 Astrocyte-conditioned medium attenuates glutamate-induced apoptotic cell death in primary cultured spinal cord neurons of rats PMCID:    Pubmed No.:26038835 Effects of 4-methylumbelliferone and high molecular weight hyaluronic acid on the inflammation of corneal stromal cells induced by LPS PMCID:    Pubmed No.:27924359 Induced differentiation of human gingival fibroblasts into VSMC-like cells PMCID:    Pubmed No.:28107746 Antitumor effects and the underlying mechanism of licochalcone A combined with 5-fluorouracil in gastric cancer cells PMCID:    Pubmed No.:28454311 miR-215 suppresses proliferation and migration of non-small cell lung cancer cells PMCID:    Pubmed No.:28454402 Role of caspase-10 in the death of acute leukemia cells PMCID:    Pubmed No.:27446483 MicroRNA-203 inhibits cellular proliferation and invasion by targeting Bmi1 in non-small cell lung cancer PMCID:    Pubmed No.:26137120 Expression of AGR2 in pituitary adenomas and its association with tumor aggressiveness PMCID:    Pubmed No.:26722256 Remote limb ischemic postconditioning protects mouse brain against cerebral ischemia/reperfusion injury via upregulating expression of Nrf2, HO-1 and NQO-1 in mice PMCID:    Pubmed No.:26000916 The Expression of microRNA-223 and FAM5C in Cerebral Infarction Patients with Diabetes Mellitus PMCID:    Pubmed No.:26717922 Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway PMCID:    Pubmed No.:28280729 Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis PMCID:    Pubmed No.:27057539 Salidroside protects against kainic acid-induced status epilepticus via suppressing oxidative stress PMCID:    Pubmed No.:26940236 Renal denervation significantly attenuates cardiorenal fibrosis in rats with sustained pressure overload PMCID:    Pubmed No.:27288113 Angiotensin-(1–7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats PMCID:    Pubmed No.:26428223 miRNA-338-3p/CDK4 signaling pathway suppressed hepatic stellate cell activation and proliferation PMCID:    Pubmed No.:28095789 Mitophagy is increased during erythroid differentiation in β-thalassemia PMCID:    Pubmed No.:27796739 Decision Making: Neural Mechanisms: Involvement of protein kinase ζ in the maintenance of hippocampal long-term potentiation in rats with chronic visceral hypersensitivity PMCID:    Pubmed No.:25761958 MiR-15a/16 regulates the growth of myeloma cells, angiogenesis and antitumor immunity by inhibiting Bcl-2, VEGF-A and IL-17 expression in multiple myeloma PMCID:    Pubmed No.:27596960 Serum Amyloid a Promotes Visfatin Expression in Macrophages PMCID:    Pubmed No.:27006946 Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin α1 and phosphorylation of downstream phospholipase Cγ1 PMCID:    Pubmed No.:27484337 β-arrestin2 regulates TRAIL-induced HepG2 cell apoptosis via the Src-extracellular signal-regulated signaling pathway PMCID:    Pubmed No.:27177228 miR-20a induces cisplatin resistance of a human gastric cancer cell line via targeting CYLD PMCID:    Pubmed No.:27357419 Farnesoid X receptor deletion improves cardiac function, structure and remodeling following myocardial infarction in mice Corrigendum in /10.3892/mmr.2017.7698 PMCID:    Pubmed No.:28560412 Naringenin attenuates fibroblast activation and inflammatory response in a mechanical stretch-induced hypertrophic scar mouse model PMCID:    Pubmed No.:28849050 Rapamycin protects neurons from brain contusion‑induced inflammatory reaction via modulation of microglial activation PMCID:    Pubmed No.:26458361 FAM172A protein promotes the proliferation of human papillary thyroid carcinoma cells via the p38 mitogen-activated protein kinase pathway PMCID:    Pubmed No.:26573560 The Inhibitory Effect of Eplerenone on Cell Proliferation in the Contralateral Kidneys of Rats with Unilateral Ureteral Obstruction PMCID:    Pubmed No.:28402979 RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal PMCID:    Pubmed No.:27389190 CPNE1 Is a Useful Prognostic Marker and Is Associated with TNF Receptor-Associated Factor 2 (TRAF2) Expression in Prostate Cancer PMCID:    Pubmed No.:29151113 Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells PMCID:    Pubmed No.:26340669 Daphnetin protects oxidative stress‑induced neuronal apoptosis via regulation of MAPK signaling and HSP70 expression PMCID:    Pubmed No.:27588145 miR‑135b inhibits tumour metastasis in prostate cancer by targeting STAT6 PMCID:    Pubmed No.:26870245 Oncostatin M was associated with thrombosis in patients with atrial fibrillation PMCID:    Pubmed No.:28471981 Antiviral Activity of Paulownia tomentosa against Enterovirus 71 of Hand, Foot, and Mouth Disease PMCID:    Pubmed No.:25744451 SEW2871 alleviates the severity of caerulein-induced acute pancreatitis in mice PMCID:    Pubmed No.:25948069 Early adolescent stress‐induced changes in prefrontal cortex miRNA‐135a and hippocampal miRNA‐16 in male rats PMCID:    Pubmed No.:28944448 High salt medium activates RhoA/ROCK and downregulates eNOS expression via the upregulation of ADMA PMCID:    Pubmed No.:27175806 Anti‑fibrotic effect of Sedum sarmentosum Bunge extract in kidneys via the hedgehog signaling pathway PMCID:    Pubmed No.:28560403 Effects of all‑trans retinoic acid on VEGF and HIF‑1α expression in glioma cells under normoxia and hypoxia and its anti‑angiogenic effect in an intracerebral glioma model PMCID:    Pubmed No.:25201493 Chinese herb extract improves liver steatosis by promoting the expression of high molecular weight adiponectin in NAFLD rats PMCID:    Pubmed No.:28849192 Neutrophil extracellular traps contribute to the intestine damage in endotoxemic rats PMCID:    Pubmed No.:25575734 Wushenziye Formula Improves Skeletal Muscle Insulin Resistance in Type 2 Diabetes Mellitus via PTP1B-IRS1-Akt-GLUT4 Signaling Pathway PMCID:    Pubmed No.:29479370 Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide PMCID:    Pubmed No.:26798404 Neuroprotection of Sanhua Decoction against Focal Cerebral Ischemia/Reperfusion Injury in Rats through a Mechanism Targeting Aquaporin 4 PMCID:    Pubmed No.:26089944 Curcumin Protects Neurons from Glutamate-Induced Excitotoxicity by Membrane Anchored AKAP79-PKA Interaction Network PMCID:    Pubmed No.:26170881 Expression of decorin in intestinal tissues of mice with inflammatory bowel disease and its correlation with autophagy PMCID:    Pubmed No.:28105121  Unregulated long non‑coding RNA‑AK058003 promotes the proliferation, invasion and metastasis of breast cancer by regulating the expression levels of the γ‑synuclein gene PMCID:    Pubmed No.:26136884 Sheng-Mai-San attenuates contractile dysfunction and structural damage induced by chronic intermittent hypoxia in mice PMCID:    Pubmed No.:26481374 Effects of ethanol extract of Bombax ceiba leaves and its main constituent mangiferin on diabetic nephropathy in mice PMCID:    Pubmed No.:26481374 Increases in the expression of Na+/H+ exchanger 1 and 3 are associated with insulin signalling in the ruminal epithelium PMCID:    Pubmed No.:29027700 MicroRNA-939 down-regulates CD2-associated protein by targeting promoter in HEK-293T cells PMCID:    Pubmed No.:26895305 Yangjing Capsule extract promotes proliferation of GC-1 spg cells via up-regulated POU3F1 pathway PMCID:    Pubmed No.:28154340 Dysregulation of the NLRP3 inflammasome complex and related cytokines in patients with multiple myeloma PMCID:    Pubmed No.:26146985 Orientin Attenuates Cerebral Ischemia/Reperfusion Injury in Rat Model through the AQP-4 and TLR4/NF-κB/TNF-α Signaling Pathway PMCID:    Pubmed No.:28645524 Which play a more important role in the development of large-sized prostates (≥80 ml), androgen receptors or oestrogen receptors? A comparative study PMCID:    Pubmed No.:26685888 Modulation of expression of 17-Hydroxylase/17,20 lyase (CYP17) and P450 aromatase (CYP19) by inhibition of MEK1 in a human ovarian granulosa-like tumor cell line PMCID:    Pubmed No.:26526982 Relaxin Inhibits High Glucose-Induced Matrix Accumulation in Human Mesangial Cells by Interfering with TGF-β1 Production and Mesangial Cells Phenotypic Transition PMCID:    Pubmed No.:26424011 Hypoxia‑inducible factor 1α participates in hypoxia‑induced epithelial‑mesenchymal transition via response gene to complement 32 PMCID:    Pubmed No.:28810656 Effect of Advanced Oxidation Protein Products on Articular Cartilage and Synovium in a Rabbit Osteoarthritis Model PMCID:    Pubmed No.:26033998 Bergenin suppresses the growth of colorectal cancer cells by inhibiting PI3K/AKT/mTOR signaling pathway PMCID:    Pubmed No.:37259388 Advanced glycation end products influence mitochondrial fusion-fission dynamics through RAGE in human aortic endothelial cells PMCID:    Pubmed No.:31966653 Role of AP-1 in the tobacco smoke-induced urocystic abnormal cell differentiation and epithelial-mesenchymal transition in vivo PMCID:    Pubmed No.:31966675 Differences in Akt signaling and metabolism gene expression in the right heart, intraventricular septum and left heart of rodents PMCID:    Pubmed No.:26722484 Inhibition of tobacco smoke-induced bladder MAPK activation and epithelial-mesenchymal transition in mice by curcumin PMCID:    Pubmed No.:26191140 Grb2-associated binder 2 silencing impairs growth and migration of H1975 cells via modulation of PI3K-Akt signaling PMCID:    Pubmed No.:26617767 Ethyl acetate extracts of Fructus Ligustri Lucide induce cell apoptosis in human neuroglioma cell PMCID:    Pubmed No.:26064281 Expression of miRNA-1233 in placenta from patients with hypertensive disorder complicating pregnancy and its role in disease pathogenesis PMCID:    Pubmed No.:26309567 MiR181c inhibits ovarian cancer metastasis and progression by targeting PRKCD expression PMCID:    Pubmed No.:26629004 Role of WNT1-inducible-signaling pathway protein 1 in etoposide resistance in lung adenocarcinoma A549 cells PMCID:    Pubmed No.:26628978 A three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics PMCID:    Pubmed No.:27486877 Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice PMCID:    Pubmed No.:27528227 Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer PMCID:    Pubmed No.:27563814 Positive expression of NR6A1/CT150 as a predictor of biochemical recurrence-free survival in prostate cancer patients PMCID:    Pubmed No.:28969082 MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells PMCID:    Pubmed No.:27765914 Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway PMCID:    Pubmed No.:27776340 Overexpression of PKM2 promotes mitochondrial fusion through attenuated p53 stability PMCID:    Pubmed No.:27801666 Long noncoding RNA BX357664 regulates cell proliferation and epithelial-to-mesenchymal transition via inhibition of TGF-β1/p38/HSP27 signaling in renal cell carcinoma PMCID:    Pubmed No.:27806310 MicroRNA-30e reduces cell growth and enhances drug sensitivity to gefitinib in lung carcinoma PMCID:    Pubmed No.:27992364 Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue PMCID:    Pubmed No.:28030827 Increased autophagy in fibroblast-like synoviocytes leads to immune enhancement potential in rheumatoid arthritis PMCID:    Pubmed No.:28053286 Cigarette smoke induced urocystic epithelial mesenchymal transition via MAPK pathways PMCID:    Pubmed No.:28060741 Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases PMCID:    Pubmed No.:28086217 Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells PMCID:    Pubmed No.:28157699 MicroRNA-29b Inhibits Angiogenesis by Targeting VEGFA through the MAPK/ERK and PI3K/Akt Signaling Pathways in Endometrial Carcinoma PMCID:    Pubmed No.:28222438 Interferon alpha antagonizes the anti-hepatoma activity of the oncolytic virus M1 by stimulating anti-viral immunity PMCID:    Pubmed No.:28445966 Invasive Fusobacterium nucleatum activates beta-catenin signaling in colorectal cancer via a TLR4/P-PAK1 cascade PMCID:    Pubmed No.:28423670 Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines PMCID:    Pubmed No.:28410239 Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells PMCID:    Pubmed No.:28422741 Krüppel-like factor 17 inhibits urokinase plasminogen activator gene expression to suppress cell invasion through the Src/p38/MAPK signaling pathway in human lung adenocarcinoma PMCID:    Pubmed No.:28454121 αMSH inhibits adipose inflammation via reducing FoxOs transcription and blocking Akt/JNK pathway in mice PMCID:    Pubmed No.:28514752 p70S6K promotes IL-6-induced epithelial-mesenchymal transition and metastasis of head and neck squamous cell carcinoma PMCID:    Pubmed No.:27174914 Crosstalk between the HIF-1 and Toll-like receptor/nuclear factor-κB pathways in the oral squamous cell carcinoma microenvironment PMCID:    Pubmed No.:27191981 Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity PMCID:    Pubmed No.:27248172 4,4′-diaponeurosporene, a C30 carotenoid, effectively activates dendritic cells via CD36 and NF-κB signaling in a ROS independent manner PMCID:    Pubmed No.:27276712 ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway PMCID:    Pubmed No.:27340870 Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling PMCID:    Pubmed No.:27367023 TGF-β induces M2-like macrophage polarization via SNAIL-mediated suppression of a pro-inflammatory phenotype PMCID:    Pubmed No.:27418133 LncRNA-SVUGP2 suppresses progression of hepatocellular carcinoma PMCID:    Pubmed No.:29228655 Heparin-based coacervate of bFGF facilitates peripheral nerve regeneration by inhibiting endoplasmic reticulum stress following sciatic nerve injury PMCID:    Pubmed No.:28624802 Up-regulation of IRF-3 expression through GATA-1 acetylation by histone deacetylase inhibitor in lung adenocarcinoma A549 cells PMCID:    Pubmed No.:29100282 A novel deubiquitinase inhibitor b-AP15 triggers apoptosis in both androgen receptor-dependent and -independent prostate cancers PMCID:    Pubmed No.:28968984 Repression of intestinal transporters and FXR-FGF15 signaling explains bile acids dysregulation in experimental colitis-associated colon cancer PMCID:    Pubmed No.:28969019 Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma PMCID:    Pubmed No.:28938620 Let-7a inhibits migration, invasion and tumor growth by targeting AKT2 in papillary thyroid carcinoma PMCID:    Pubmed No.:29050238 Curcumin reverses benzidine-induced cell proliferation by suppressing ERK1/2 pathway in human bladder cancer T24 cells PMCID:    Pubmed No.:26776764 Upregulation of CD44v6 contributes to acquired chemoresistance via the modulation of autophagy in colon cancer SW480 cells PMCID:    Pubmed No.:26747179 Lithium Ameliorates LPS-Induced Astrocytes Activation Partly via Inhibition of Toll-Like Receptor 4 Expression PMCID:    Pubmed No.:26870942 Decreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivo PMCID:    Pubmed No.:27009808 Metformin and AICAR regulate NANOG expression via the JNK pathway in HepG2 cells independently of AMPK PMCID:    Pubmed No.:26939902 MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer PMCID:    Pubmed No.:26989074 Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells PMCID:    Pubmed No.:27027340 Effect of Golgi phosphoprotein 2 (GOLPH2/GP73) on autophagy in human hepatocellular carcinoma HepG2 cells PMCID:    Pubmed No.:25527157 miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells PMCID:    Pubmed No.:25762621 Bufalin Induces Mitochondrial Pathway-Mediated Apoptosis in Lung Adenocarcinoma Cells PMCID:    Pubmed No.:25556498 Down-regulation of HDAC3 inhibits growth of cholangiocarcinoma by inducing apoptosis PMCID:    Pubmed No.:29245911 Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation PMCID:    Pubmed No.:28938531 Reduced expression of BMP3 contributes to the development of pulmonary fibrosis and predicts the unfavorable prognosis in IIP patients PMCID:    Pubmed No.:29113323 Angiotensin-(1-7) in Paraventricular Nucleus Contributes to the Enhanced Cardiac Sympathetic Afferent Reflex and Sympathetic Activity in Chronic Heart Failure Rats PMCID:    Pubmed No.:28848201 Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes PMCID:    Pubmed No.:29221131 Cofilin 1 promotes bladder cancer and is regulated by TCF7L2 PMCID:    Pubmed No.:29190896 Trimedazidine alleviates pulmonary artery banding-induced acute right heart dysfunction and activates PRAS40 in rats PMCID:    Pubmed No.:29190898 Shikonin reduces tamoxifen resistance through long non-coding RNA uc.57 PMCID:    Pubmed No.:29179465 Expression of the β3 subunit of Na+/K+-ATPase is increased in gastric cancer and regulates gastric cancer cell progression and prognosis via the PI3/AKT pathway PMCID:    Pubmed No.:29137423 GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1 expression via activation of AMPK/FOXO3a pathway PMCID:    Pubmed No.:26327408 Afatinib reverses multidrug resistance in ovarian cancer via dually inhibiting ATP binding cassette subfamily B member 1 PMCID:    Pubmed No.:26317651 8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition PMCID:    Pubmed No.:26316083 Periostin expression in intra-tumoral stromal cells is prognostic and predictive for colorectal carcinoma via creating a cancer-supportive niche PMCID:    Pubmed No.:26556874 Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo PMCID:    Pubmed No.:26625200 MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1 PMCID:    Pubmed No.:26673620 Long non-coding RNA CCAT1 modulates neuropathic pain progression through sponging miR-155 PMCID:    Pubmed No.:29163801 Inhibition of the SOCS1-JAK2-STAT3 Signaling Pathway Confers Neuroprotection in Rats with Ischemic Stroke PMCID:    Pubmed No.:29130998 NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway PMCID:    Pubmed No.:29296214 Significance of the E3 ubiquitin protein UBR5 as an oncogene and a prognostic biomarker in colorectal cancer PMCID:    Pubmed No.:29296225 Reduction of Uterine Perfusion Pressure Induced Redistribution of Endothelin Receptor Type-B Between the Intima and Media Contributes to the Pathogenesis of Pregnancy-Induced Hypertension PMCID:    Pubmed No.:29216636 miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A PMCID:    Pubmed No.:26023735 Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors PMCID:    Pubmed No.:33186520 Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity PMCID:    Pubmed No.:32277911 A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis PMCID:    Pubmed No.:29754779 Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing PMCID:    Pubmed No.:30804553 Anesthetic Propofol Promotes Tumor Metastasis in Lungs via GABAAR-Dependent TRIM21 Modulation of Src Expression PMCID:    Pubmed No.:34263559 Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes PMCID:    Pubmed No.:31358756 The δ subunit of F1Fo-ATP synthase is required for pathogenicity of Candida albicans PMCID:    Pubmed No.:34654833 The δ subunit of F1Fo-ATP synthase is required for pathogenicity of Candida albicans PMCID:    Pubmed No.:34654833 GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain PMCID:    Pubmed No.:30010619 Injectable AuNP-HA matrix with localized stiffness enhances the formation of gap junction in engrafted human induced pluripotent stem cell-derived cardiomyocytes and promotes cardiac repair PMCID:    Pubmed No.:34739980 SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis PMCID:    Pubmed No.:31932588 ZZ-dependent regulation of p62/SQSTM1 in autophagy PMCID:    Pubmed No.:30349045 Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1 PMCID:    Pubmed No.:33484341 Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation PMCID:    Pubmed No.:30962431 DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage PMCID:    Pubmed No.:30337542 GATA4-driven miR-206-3p signatures control orofacial bone development by regulating osteogenic and osteoclastic activity PMCID:    Pubmed No.:34373748 Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer PMCID:    Pubmed No.:32248842 Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer PMCID:    Pubmed No.:34429133 The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression PMCID:    Pubmed No.:31126313 Sirtuin 6 is a negative regulator of FcεRI signaling and anaphylactic responses PMCID:    Pubmed No.:34051221 HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation PMCID:    Pubmed No.:31863069 Sirtuin 6 in preosteoclasts suppresses age- and estrogen deficiency-related bone loss by stabilizing estrogen receptor α PMCID:    Pubmed No.:30787391 Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer PMCID:    Pubmed No.:29685157 Depletion of glioma stem cells by synergistic inhibition of mTOR and c-Myc with a biological camouflaged cascade brain-targeting nanosystem PMCID:    Pubmed No.:33296794 Gold nanoparticles modulate the crosstalk between macrophages and periodontal ligament cells for periodontitis treatment PMCID:    Pubmed No.:30933774 Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats PMCID:    Pubmed No.:29609091 Symmetrical dimethylation of H4R3: A bridge linking DNA damage and repair upon oxidative stress PMCID:    Pubmed No.:32739156 Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring PMCID:    Pubmed No.:34731622 Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK PMCID:    Pubmed No.:32283380 Sirt1-Overexpressing Mesenchymal Stem Cells Drive the Anti-tumor Effect through Their Pro-inflammatory Capacity PMCID:    Pubmed No.:32027844 CRISPR/Cas9-Mediated miR-29b Editing as a Treatment of Different Types of Muscle Atrophy in Mice PMCID:    Pubmed No.:32222157 A Novel mTORC1/2 Inhibitor (MTI-31) Inhibits Tumor Growth, Epithelial–Mesenchymal Transition, Metastases, and Improves Antitumor Immunity in Preclinical Models of Lung Cancer PMCID:    Pubmed No.:30796032 EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop PMCID:    Pubmed No.:34484860 Controlling the Multiscale Network Structure of Fibers To Stimulate Wound Matrix Rebuilding by Fibroblast Differentiation PMCID:    Pubmed No.:31251577 Repurposing the anthelmintic praziquantel to treat psoriasis PMCID:    Pubmed No.:34363611 Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis PMCID:    Pubmed No.:31541078 Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I. PMCID:    Pubmed No.:33408776 KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia PMCID:    Pubmed No.:33456567 Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development PMCID:    Pubmed No.:33754063 Fusobacterium nucleatum Promotes Metastasis in Colorectal Cancer by Activating Autophagy Signaling via the Upregulation of CARD3 Expression PMCID:    Pubmed No.:31903123 SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride PMCID:    Pubmed No.:32308752 The anti-microbial peptide LL-37/CRAMP levels are associated with acute heart failure and can attenuate cardiac dysfunction in multiple preclinical models of heart failure PMCID:    Pubmed No.:32483446 Statin suppresses sirtuin 6 through miR-495, increasing FoxO1-dependent hepatic gluconeogenesis PMCID:    Pubmed No.:33052223 Rho-GEF Trio regulates osteosarcoma progression and osteogenic differentiation through Rac1 and RhoA PMCID:    Pubmed No.:34893584 MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes PMCID:    Pubmed No.:31127093 ATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients PMCID:    Pubmed No.:33846304 A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels PMCID:    Pubmed No.:33934099 Oxytocin receptor induces mammary tumorigenesis through prolactin/p-STAT5 pathway PMCID:    Pubmed No.:34099636 LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway PMCID:    Pubmed No.:34108447 HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury PMCID:    Pubmed No.:34666797 Complement factor B in high glucose–induced podocyte injury and diabetic kidney disease PMCID:    Pubmed No.:34622800 S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction PMCID:    Pubmed No.:31694393 Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury PMCID:    Pubmed No.:30782145 Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction PMCID:    Pubmed No.:34837851 SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States PMCID:    Pubmed No.:31914391 Glutathione S-transferases P1 protects breast cancer cell from adriamycin-induced cell death through promoting autophagy PMCID:    Pubmed No.:30683915 HSPA12A is required for adipocyte differentiation and diet-induced obesity through a positive feedback regulation with PPARγ PMCID:    Pubmed No.:30742088 MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2 PMCID:    Pubmed No.:29290822 Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake PMCID:    Pubmed No.:31534545 LncRNA KTN1-AS1 promotes the progression of non-small cell lung cancer via sponging of miR-130a-5p and activation of PDPK1 PMCID:    Pubmed No.:32820252 ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development PMCID:    Pubmed No.:31116980 Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression PMCID:    Pubmed No.:31539804 HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice PMCID:    Pubmed No.:32086291 Decreased Level of Exosomal miR-5121 Released from Microglia Suppresses Neurite Outgrowth and Synapse Recovery of Neurons Following Traumatic Brain Injury PMCID:    Pubmed No.:33475953 CBP Bromodomain Inhibition Rescues Mice From Lethal Sepsis Through Blocking HMGB1-Mediated Inflammatory Responses PMCID:    Pubmed No.:33603756 HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages. PMCID:    Pubmed No.:34531848 Interferon-Inducible LINC02605 Promotes Antiviral Innate Responses by Strengthening IRF3 Nuclear Translocation. PMCID:    Pubmed No.:34804040 A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells PMCID:    Pubmed No.:33319461 Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation PMCID:    Pubmed No.:30980867 Kynurenic acid/GPR35 axis restricts NLRP3 inflammasome activation and exacerbates colitis in mice with social stress PMCID:    Pubmed No.:30790702 Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29b PMCID:    Pubmed No.:34116237 Inhibiting Protein Kinase Activity of Pyruvate Kinase M2 by SIRT2 Deacetylase Attenuates Psoriasis PMCID:    Pubmed No.:32679047 Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy PMCID:    Pubmed No.:30972284 TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis PMCID:    Pubmed No.:31433805 Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway PMCID:    Pubmed No.:31783879 Fusobacterium nucleatum promotes M2 polarization of macrophages in the microenvironment of colorectal tumours via a TLR4-dependent mechanism PMCID:    Pubmed No.:30121899 SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury PMCID:    Pubmed No.:33854356 Regulation of the integrin αVβ3- actin filaments axis in early osteogenesis of human fibroblasts under cyclic tensile stress PMCID:    Pubmed No.:34620239 Bisphenol A Exposure Induces Apoptosis and Impairs Early Embryonic Development in Xenopus laevis1 PMCID:    Pubmed No.:33773307 Hyperactivated Wnt-β-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2 PMCID:    Pubmed No.:33109217 PRRX1 deficiency induces mesenchymal‐epithelial transition through PITX2/miR‐200–dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma PMCID:    Pubmed No.:33587761 Functional recovery of a novel knockin mouse model of dysferlinopathy by readthrough of nonsense mutation PMCID:    Pubmed No.:34141825 Curculigoside Ameliorates Bone Loss by Influencing Mesenchymal Stem Cell Fate in Aging Mice. PMCID:    Pubmed No.:34926455 Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells PMCID:    Pubmed No.:34222256 EHD1 impairs decidualization by regulating the Wnt4/β-catenin signaling pathway in recurrent implantation failure PMCID:    Pubmed No.:31707150 Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1 PMCID:    Pubmed No.:30093307 LSD1 suppresses invasion, migration and metastasis of luminal breast cancer cells via activation of GATA3 and repression of TRIM37 expression PMCID:    Pubmed No.:31409898 Tspan5 promotes epithelial–mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling PMCID:    Pubmed No.:33955149 Ursolic Acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in NSCLCs harboring EGFR T790M PMCID:    Pubmed No.:31322286 Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation‐related signalling pathways PMCID:    Pubmed No.:31454852 Disrupted hepatic pentose phosphate pathway directly participates in and indirectly promotes cyp3a‐reduction: a new strategy for cyp3a‐mediated drug hepatotoxicity PMCID:    Pubmed No.:31670839 Mir24-2-5p suppresses the osteogenic differentiation with Gnai3 inhibition presenting a direct target via inactivating JNK-p38 MAPK signaling axis PMCID:    Pubmed No.:34803495 Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway PMCID:    Pubmed No.:33867836 PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism PMCID:    Pubmed No.:33250241 Cytotoxicity of hexabromocyclododecane, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane and 1,2,5,6-tetrabromocyclooctane in human SH-SY5Y neuroblastoma cells PMCID:    Pubmed No.:32758930 Cytotoxicity of hexabromocyclododecane, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane and 1,2,5,6-tetrabromocyclooctane in human SH-SY5Y neuroblastoma cells PMCID:    Pubmed No.:32758930 Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer PMCID:    Pubmed No.:34804370 MICAL2 Contributes to Gastric Cancer Cell Proliferation by Promoting YAP Dephosphorylation and Nuclear Translocation PMCID:    Pubmed No.:34650666 Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps PMCID:    Pubmed No.:33868571 Therapeutic evaluation of acupoint stimulation with needle-scapelon on rat model of degenerative cervical intervertebral discs PMCID:    Pubmed No.:30553194 Coronary hypercontractility to acidosis owes to the greater activity of TMEM16A/ANO1 in the arterial smooth muscle cells PMCID:    Pubmed No.:34243598 Differential toxicities of triptolide to immortalized podocytes and the podocytes in vivo PMCID:    Pubmed No.:30551497 Post-transcription mediated Snail stabilization is involved in radiation exposure induced invasion and migration of hepatocarcinoma cells PMCID:    Pubmed No.:29684855 Photothermal and gene therapy combined with immunotherapy to gastric cancer by the gold nanoshell-based system PMCID:    Pubmed No.:31277667 Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents PMCID:    Pubmed No.:33933753 Small regulatory polypeptide of amino acid response negatively relates to poor prognosis and controls hepatocellular carcinoma progression via regulating microRNA-5581-3p/human cardiolipin synthase 1 PMCID:    Pubmed No.:30825207 Involvement of TRPV4 in changes in rapidly inactivating potassium channels in the early stage of pilocarpine-induced status epilepticus in mice PMCID:    Pubmed No.:34415059 Long non-coding RNA MCM3AP-AS1 promotes growth and migration through modulating FOXK1 by sponging miR-138-5p in pancreatic cancer PMCID:    Pubmed No.:31830901 HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models PMCID:    Pubmed No.:29113455 The concentration of tumor necrosis factor-α determines its protective or damaging effect on liver injury by regulating Yap activity PMCID:    Pubmed No.:31988281 A lincRNA-p21/miR-181 family feedback loop regulates microglial activation during systemic LPS- and MPTP- induced neuroinflammation PMCID:    Pubmed No.:30038357 Chondroitin polymerizing factor (CHPF) promotes development of malignant melanoma through regulation of CDK1 PMCID:    Pubmed No.:32612115 ALKBH5 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating PTEN expression in an m6A-dependent manner PMCID:    Pubmed No.:34438274 Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse PMCID:    Pubmed No.:34695613 Circ-SHPRH suppresses cadmium-induced transformation of human bronchial epithelial cells by regulating QKI expression via miR-224–5p PMCID:    Pubmed No.:34082244 TRPV3 enhances skin keratinocyte proliferation through EGFR-dependent signaling pathways PMCID:    Pubmed No.:32535744 Vacuolar Membrane ATPase Activity 21 Predicts a Favorable Outcome and Acts as a Suppressor in Colorectal Cancer PMCID:    Pubmed No.:33680927 Serpinc1 Acts as a Tumor Suppressor in Hepatocellular Carcinoma Through Inducing Apoptosis and Blocking Macrophage Polarization in an Ubiquitin-Proteasome Manner PMCID:    Pubmed No.:34881176 Screening of MicroRNA Related to Irradiation Response and the Regulation Mechanism of miRNA-96-5p in Rectal Cancer Cells PMCID:    Pubmed No.:34458143 NGF Signaling Interacts With the Hippo/YAP Pathway to Regulate Cervical Cancer Progression PMCID:    Pubmed No.:34722240 PTIP Inhibits Cell Invasion in Esophageal Squamous Cell Carcinoma via Modulation of EphA2 Expression PMCID:    Pubmed No.:33833989 Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer PMCID:    Pubmed No.:33968724 Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer PMCID:    Pubmed No.:33968724 Eukaryotic Translation Initiation Factor 3 Subunit B Is a Promoter in the Development and Progression of Pancreatic Cancer PMCID:    Pubmed No.:33996561 The Exocrine Differentiation and Proliferation Factor (EXDPF) Gene Promotes Ovarian Cancer Tumorigenesis by Up-Regulating DNA Replication Pathway. PMCID:    Pubmed No.:34041032 Atorvastatin alleviates microglia-mediated neuroinflammation via modulating the microbial composition and the intestinal barrier function in ischemic stroke mice PMCID:    Pubmed No.:33279615 Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis PMCID:    Pubmed No.:30030103 Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II PMCID:    Pubmed No.:30502455 NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury PMCID:    Pubmed No.:34937917 S-nitrosylation of c-Jun N-terminal kinase mediates pressure overload-induced cardiac dysfunction and fibrosis PMCID:    Pubmed No.:34011968 Dihydromyricetin ameliorates vascular calcification in chronic kidney disease by targeting AKT signaling PMCID:    Pubmed No.:34643227 Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer PMCID:    Pubmed No.:30250021 Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance PMCID:    Pubmed No.:33008458 Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy PMCID:    Pubmed No.:35509816 Sirt3 Protects Against Thoracic Aortic Dissection Formation by Reducing Reactive Oxygen Species, Vascular Inflammation, and Apoptosis of Smooth Muscle Cells PMCID:    Pubmed No.:34095262 Long noncoding RNA Q associates with Sox2 and is involved in the maintenance of pluripotency in mouse embryonic stem cells PMCID:    Pubmed No.:32277787 Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis PMCID:    Pubmed No.:31189885 Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis PMCID:    Pubmed No.:31189885 Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement PMCID:    Pubmed No.:31522191 FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival PMCID:    Pubmed No.:31740658 Regulatory roles of miR-22/Redd1-mediated mitochondrial ROS and cellular autophagy in ionizing radiation-induced BMSC injury PMCID:    Pubmed No.:30846680 TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice PMCID:    Pubmed No.:31097691 miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma PMCID:    Pubmed No.:29531296 miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma PMCID:    Pubmed No.:29531296 CDC42 promotes vascular calcification in chronic kidney disease PMCID:    Pubmed No.:31397884 LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis PMCID:    Pubmed No.:31982491 Mangiferin activates Nrf2 to attenuate cardiac fibrosis via redistributing glutaminolysis-derived glutamate PMCID:    Pubmed No.:32353588 Scutellarin, a modulator of mTOR, attenuates hepatic insulin resistance by regulating hepatocyte lipid metabolism via SREBP-1c suppression PMCID:    Pubmed No.:31828866 Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway PMCID:    Pubmed No.:34859513 Tanshinone IIA Activates Nuclear Factor-Erythroid 2-Related Factor 2 to Restrain Pulmonary Fibrosis via Regulation of Redox Homeostasis and Glutaminolysis PMCID:    Pubmed No.:30105924 Fusobacterium nucleatum Activates Endoplasmic Reticulum Stress to Promote Crohn’s Disease Development via the Upregulation of CARD3 Expression PMCID:    Pubmed No.:32153411 Combined Treatment With 2-(2-Benzofu-Ranyl)-2-Imidazoline and Recombinant Tissue Plasminogen Activator Protects Blood–Brain Barrier Integrity in a Rat Model of Embolic Middle Cerebral Artery Occlusion PMCID:    Pubmed No.:32595494 Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer PMCID:    Pubmed No.:34305593 A Single, Acute Astragaloside IV Therapy Protects Cardiomyocyte Through Attenuating Superoxide Anion-Mediated Accumulation of Autophagosomes in Myocardial Ischemia-Reperfusion Injury PMCID:    Pubmed No.:34349641 Glycoproteins From Rabdosia japonica var. glaucocalyx Regulate Macrophage Polarization and Alleviate Lipopolysaccharide-Induced Acute Lung Injury in Mice via TLR4/NF-κB Pathway PMCID:    Pubmed No.:34366849 Effect of tryptase on mouse brain microvascular endothelial cells via protease-activated receptor 2 PMCID:    Pubmed No.:30170602 NLRP3 Inflammasome-Dependent Increases in High Mobility Group Box 1 Involved in the Cognitive Dysfunction Caused by Tau-Overexpression PMCID:    Pubmed No.:34539383 Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children PMCID:    Pubmed No.:30659323 A new gold(I) complex-Au(PPh3)PT is a deubiquitinase inhibitor and inhibits tumor growth PMCID:    Pubmed No.:30527624 Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta PMCID:    Pubmed No.:32949999 NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth PMCID:    Pubmed No.:34774047 Knockdown of POLQ interferes the development and progression of hepatocellular carcinoma through regulating cell proliferation, apoptosis and migration PMCID:    Pubmed No.:34517891 RPL35A is a key promotor involved in the development and progression of gastric cancer PMCID:    Pubmed No.:34535139 The effects of MEX3A knockdown on proliferation, apoptosis and migration of osteosarcoma cells PMCID:    Pubmed No.:33827584 Trichostatin A downregulates bromodomain and extra-terminal proteins to suppress osimertinib resistant non-small cell lung carcinoma PMCID:    Pubmed No.:33858423 Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo PMCID:    Pubmed No.:33931059 CircRNA NALCN acts as an miR-493-3p sponge to regulate PTEN expression and inhibit glioma progression PMCID:    Pubmed No.:34112159 Network analysis of KLF5 targets showing the potential oncogenic role of SNHG12 in colorectal cancer PMCID:    Pubmed No.:32943987 Suppression of CCDC6 sensitizes tumor to oncolytic virus M1 PMCID:    Pubmed No.:33338804 Real-Time Visualization and Quantification of Oncolytic M1 Virus In Vitro and In Vivo PMCID:    Pubmed No.:33504253 Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice PMCID:    Pubmed No.:31048563 Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer PMCID:    Pubmed No.:34623971 Near-infrared light-activatable siRNA delivery by microcapsules for combined tumour therapy PMCID:    Pubmed No.:29527926 miR-33a-5p enhances the sensitivity of lung adenocarcinoma cells to celastrol by regulating mTOR signaling PMCID:    Pubmed No.:29484434 Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway PMCID:    Pubmed No.:31234944 MicroRNA-663 facilitates the growth, migration and invasion of ovarian cancer cell by inhibiting TUSC2 PMCID:    Pubmed No.:30944041 Baicalin regulates SirT1/STAT3 pathway and restrains excessive hepatic glucose production PMCID:    Pubmed No.:30144531 Glycochenodeoxycholate promotes the metastasis of gallbladder cancer cells by inducing epithelial to mesenchymal transition via activation of SOCS3/JAK2/STAT3 signaling pathway PMCID:    Pubmed No.:31347168 Dynamic recognition and repair of DNA complex damage PMCID:    Pubmed No.:30537094 Phosphoinositide 3‐kinase/protein kinase B inhibition restores regulatory T cell's function in pulmonary sarcoidosis PMCID:    Pubmed No.:30945303 Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy PMCID:    Pubmed No.:30585174 Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis PMCID:    Pubmed No.:33889074 Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice PMCID:    Pubmed No.:30699097 Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke PMCID:    Pubmed No.:34553133 TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency PMCID:    Pubmed No.:31959867 Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes PMCID:    Pubmed No.:31028245 Osterix regulates corticalization for longitudinal bone growth via integrin β3 expression PMCID:    Pubmed No.:30022046 Autophagy Activation is Associated with Neuroprotection in Diabetes-associated Cognitive Decline PMCID:    Pubmed No.:31788335 Involvement of the MiR-181b-5p/HMGB1 Pathway in Ang II-induced Phenotypic Transformation of Smooth Muscle Cells in Hypertension PMCID:    Pubmed No.:31011475 Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain PMCID:    Pubmed No.:29896426 Baicalin protects against insulin resistance and metabolic dysfunction through activation of GALR2/GLUT4 signaling PMCID:    Pubmed No.:34923235 Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility PMCID:    Pubmed No.:31005715 Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Accelerate Cutaneous Wound Healing by Enhancing Angiogenesis through Delivering Angiopoietin-2 PMCID:    Pubmed No.:32613452 A-kinase-interacting protein 1 facilitates growth and metastasis of gastric cancer cells via Slug-induced epithelial-mesenchymal transition PMCID:    Pubmed No.:31020809 Lactobacillus Protects Against S. Typhimurium–Induced Intestinal Inflammation by Determining the Fate of Epithelial Proliferation and Differentiation PMCID:    Pubmed No.:31953989 Fecal Microbiota Transplantation Protects the Intestinal Mucosal Barrier by Reconstructing the Gut Microbiota in a Murine Model of Sepsis PMCID:    Pubmed No.:34631604 LncRNA ENSMUST00000155383 is Involved in the Improvement of DPP-4 Inhibitor MK-626 on Vascular Endothelial Function by Modulating Cacna1c-Mediated Ca2+ Influx in Hypertensive Mice PMCID:    Pubmed No.:34368236 MicroRNA‐219 decreases hippocampal long‐term potentiation inhibition and hippocampal neuronal cell apoptosis in type 2 diabetes mellitus mice by suppressing the NMDAR signaling pathway PMCID:    Pubmed No.:29804319 AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke PMCID:    Pubmed No.:34156153 Regulation of Bax-dependent apoptosis by mitochondrial deubiquitinase USP30 PMCID:    Pubmed No.:34381024 c-Myc Is a Major Determinant for Antitumor Activity of Aurora A Kinase Inhibitor MLN8237 in Thyroid Cancer PMCID:    Pubmed No.:30226440 The Krüppel-like factor 15-NFATc1 axis ameliorates podocyte injury: a novel rationale for using glucocorticoids in proteinuria diseases PMCID:    Pubmed No.:32478397 Targeting POLE2 Creates a Novel Vulnerability in Renal Cell Carcinoma via Modulating Stanniocalcin 1 PMCID:    Pubmed No.:33644060 Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Random Skin Flaps via ROS Elimination PMCID:    Pubmed No.:33898433 Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A–Smad2/3 in rats following myocardial infarction PMCID:    Pubmed No.:33932887 Dysregulation of UDP-glucuronosyltransferases in CCl4 induced liver injury rats PMCID:    Pubmed No.:32380060 The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply PMCID:    Pubmed No.:31425655 Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR-miR-429 pathway PMCID:    Pubmed No.:33811696 Proteomics and bioinformatics reveal insights into neuroinflammation in the acute to subacute phases in rat models of spinal cord contusion injury PMCID:    Pubmed No.:34143440 Cullin 2-RBX1 E3 ligase and USP2 regulate antithrombin ubiquitination and stability PMCID:    Pubmed No.:34324733 EIF3H interacts with PDCD4 enhancing lung adenocarcinoma cell metastasis PMCID:    Pubmed No.:32064160 The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO PMCID:    Pubmed No.:34714466 Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis PMCID:    Pubmed No.:31718671 Circ_0088194 Promotes the Invasion and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the miR-766-3p/MMP2 Axis PMCID:    Pubmed No.:33692802 Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells PMCID:    Pubmed No.:34157397 Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats PMCID:    Pubmed No.:31827689 Farrerol Directly Targets GSK-3β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries PMCID:    Pubmed No.:32082480 Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits PMCID:    Pubmed No.:32685087 ERK1/2-HNF4α axis is involved in epigallocatechin-3-gallate inhibition of HBV replication PMCID:    Pubmed No.:31554961 Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression PMCID:    Pubmed No.:30150788 Isoflavones enhance pharmacokinetic exposure of active lovastatin acid via the upregulation of carboxylesterase in high-fat diet mice after oral administration of Xuezhikang capsules PMCID:    Pubmed No.:29921884 Oral administration of curcumin ameliorates pulmonary fibrosis in mice through 15d-PGJ2-mediated induction of hepatocyte growth factor in the colon PMCID:    Pubmed No.:32694760 Quercetin prevents bone loss in hindlimb suspension mice via stanniocalcin 1-mediated inhibition of osteoclastogenesis PMCID:    Pubmed No.:32934346 Berberine inhibits colorectal tumor growth by suppressing SHH secretion PMCID:    Pubmed No.:32958873 Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor PMCID:    Pubmed No.:33820450 Long noncoding RNA HOTAIR promotes renal cell carcinoma malignancy through alpha‐2, 8‐sialyltransferase 4 by sponging microRNA‐124 PMCID:    Pubmed No.:30105850 Silent information regulator 1 suppresses epithelial-to-mesenchymal transition in lung cancer cells via its regulation of mitochondria status PMCID:    Pubmed No.:34119539 Proteomes analysis reveals the involvement of autophagy in AD-like neuropathology induced by noise exposure and ApoE4 PMCID:    Pubmed No.:31228807 BabaoDan attenuates high-fat diet-induced non-alcoholic fatty liver disease via activation of AMPK signaling PMCID:    Pubmed No.:31548878 Modification of α2,6‐sialylation mediates the invasiveness and tumorigenicity of non‐small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway PMCID:    Pubmed No.:29981167 The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome PMCID:    Pubmed No.:31914678 Pharmacological activation of ERβ by arctigenin maintains the integrity of intestinal epithelial barrier in inflammatory bowel diseases PMCID:    Pubmed No.:31908053 The opposite functions of miR‐24 in the osteogenesis and adipogenesis of adipose‐derived mesenchymal stem cells are mediated by the HOXB7/β‐catenin complex PMCID:    Pubmed No.:32413244 PHD3 mediates denervation skeletal muscle atrophy through Nf‐κB signal pathway PMCID:    Pubmed No.:33749901 Tristetraprolin destabilizes NOX2 mRNA and protects dopaminergic neurons from oxidative damage in Parkinson's disease PMCID:    Pubmed No.:32954540 Glutathione S-transferases P1-mediated interleukin-6 in tumor-associated macrophages augments drug-resistance in MCF-7 breast cancer PMCID:    Pubmed No.:33080187 3-Bromopyruvate regulates the status of glycolysis and BCNU sensitivity in human hepatocellular carcinoma cells PMCID:    Pubmed No.:32330495 MrgprX2 regulates mast cell degranulation through PI3K/AKT and PLCγ signaling in pseudo-allergic reactions PMCID:    Pubmed No.:34920312 The levels and significance of inflammasomes in the mouse retina following optic nerve crush PMCID:    Pubmed No.:30939414 Ulinastatin mediates suppression of regulatory T cells through TLR4/NF-κB signaling pathway in murine sepsis PMCID:    Pubmed No.:30261464 The PICK1/TLR4 complex on microglia is involved in the regulation of LPS-induced sepsis-associated encephalopathy PMCID:    Pubmed No.:34500285 mTOR- and SGK-Mediated Connexin 43 Expression Participates in Lipopolysaccharide-Stimulated Macrophage Migration through the iNOS/Src/FAK Axis PMCID:    Pubmed No.:30341186 Serum- and glucocorticoid-inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1 PMCID:    Pubmed No.:33724645 l-Theanine attenuates neointimal hyperplasia via suppression of vascular smooth muscle cell phenotypic modulation PMCID:    Pubmed No.:32402912 Pro‐inflammatory role of high‐mobility group box‐1 on brain mast cells via the RAGE/NF‐κB pathway PMCID:    Pubmed No.:31520526 The Antioxidant MitoQ Protects Against CSE-Induced Endothelial Barrier Injury and Inflammation by Inhibiting ROS and Autophagy in Human Umbilical Vein Endothelial Cells PMCID:    Pubmed No.:31337974 A Long Non-coding RNA Lnc712 Regulates Breast Cancer Cell Proliferation PMCID:    Pubmed No.:31892853 RRM2 is a potential prognostic biomarker with functional significance in glioma PMCID:    Pubmed No.:30745840 Metformin suppresses inflammation and apoptosis of myocardiocytes by inhibiting autophagy in a model of ischemia-reperfusion injury PMCID:    Pubmed No.:32792857 Glibenclamide Targets Sulfonylurea Receptor 1 to Inhibit p70S6K Activity and Upregulate KLF4 Expression to Suppress Non-Small Cell Lung Carcinoma PMCID:    Pubmed No.:31341030 Knockdown of Kremen2 Inhibits Tumor Growth and Migration in Gastric Cancer PMCID:    Pubmed No.:33489867 Inhibition of CDC25B With WG-391D Impedes the Tumorigenesis of Ovarian Cancer PMCID:    Pubmed No.:31024841 Autophagy Induced by Proteasomal DUB Inhibitor NiPT Restricts NiPT-Mediated Cancer Cell Death PMCID:    Pubmed No.:32292717 Discovery of coumarin-derived imino sulfonates as a novel class of potential cardioprotective agents PMCID:    Pubmed No.:31629165 Reduced miR-203 predicts metastasis and poor survival in esophageal carcinoma PMCID:    Pubmed No.:31844033 β-arrestin2 alleviates L-dopa–induced dyskinesia via lower D1R activity in Parkinson’s rats PMCID:    Pubmed No.:31891566 TYRO3 facilitates cell growth and metastasis via activation of the Wnt/β-catenin signaling pathway in human gastric cancer cells PMCID:    Pubmed No.:32018224 Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation PMCID:    Pubmed No.:32365333 Protective effects of ginseng stem-leaf saponins on D-galactose-induced reproductive injury in male mice PMCID:    Pubmed No.:33714944 Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization PMCID:    Pubmed No.:29753749 A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan PMCID:    Pubmed No.:30733972 Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice PMCID:    Pubmed No.:30946910 CircSPAG16 suppresses cadmium-induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt PMCID:    Pubmed No.:34081812 miR-103/107 promote ER stress-mediated apoptosis via targeting the Wnt3a/β-catenin/ATF6 pathway in preadipocytes PMCID:    Pubmed No.:29483204 GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner PMCID:    Pubmed No.:31324725 A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway PMCID:    Pubmed No.:31396207 Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses PMCID:    Pubmed No.:30333836 A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis PMCID:    Pubmed No.:30425719 Gasdermin D serves as a key executioner of pyroptosis in experimental cerebral ischemia and reperfusion model both in vivo and in vitro PMCID:    Pubmed No.:30600840 Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats PMCID:    Pubmed No.:32084453 Astrocytic Yes-associated protein attenuates cerebral ischemia-induced brain injury by regulating signal transducer and activator of transcription 3 signaling PMCID:    Pubmed No.:32750359 Clinopodium chinense Attenuates Palmitic Acid-Induced Vascular Endothelial Inflammation and Insulin Resistance through TLR4-Mediated NF-κB and MAPK Pathways PMCID:    Pubmed No.:30776912 Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS‐G12D mutation and P53 knockout PMCID:    Pubmed No.:31410985 Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK‐ERK pathway PMCID:    Pubmed No.:30907511 Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK‐ERK pathway PMCID:    Pubmed No.:30907511 MICAL1 facilitates breast cancer cell proliferation via ROS‐sensitive ERK/cyclin D pathway PMCID:    Pubmed No.:29524295 6‐Gingerol Improves Ectopic Lipid Accumulation, Mitochondrial Dysfunction, and Insulin Resistance in Skeletal Muscle of Ageing Rats: Dual Stimulation of the AMPK/PGC‐1α Signaling Pathway via Plasma Adiponectin and Muscular AdipoR1 PMCID:    Pubmed No.:30575271 AR-mTOR-SRF Axis Regulates HMMR Expression in Human Prostate Cancer Cells PMCID:    Pubmed No.:34099592 Galectin-3 Interacts with C/EBPβ and Upregulates Hyaluronan-Mediated Motility Receptor Expression in Gastric Cancer PMCID:    Pubmed No.:31822520 Mechanical Strain Regulates Myofibroblast Differentiation of Human Scleral Fibroblasts by YAP PMCID:    Pubmed No.:34658907 OCT4B-190 protects against ischemic stroke by modulating GSK-3β/HDAC6 PMCID:    Pubmed No.:30981804 Sodium-glucose co-transporter-2 (SGLT-2) inhibition reduces glucose uptake to induce breast cancer cell growth arrest through AMPK/mTOR pathway PMCID:    Pubmed No.:33068934 Rhodiola crenulata root extract ameliorates fructose-induced hepatic steatosis in rats: Association with activating autophagy PMCID:    Pubmed No.:32007914 Synergistic antitumour effects of triptolide plus 10-hydroxycamptothecin onbladder cancer PMCID:    Pubmed No.:31063955 Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration PMCID:    Pubmed No.:32526459 FTO inhibits UPRmt-induced apoptosis by activating JAK2/STAT3 pathway and reducing m6A level in adipocytes PMCID:    Pubmed No.:34212271 CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration PMCID:    Pubmed No.:34412565 A potential probiotic bacterium for antipsychotic-induced metabolic syndrome: mechanisms underpinning how Akkermansia muciniphila subtype improves olanzapine-induced glucose homeostasis in mice PMCID:    Pubmed No.:34046717 PM2.5 promotes plaque vulnerability at different stages of atherosclerosis and the formation of foam cells via TLR4/MyD88/NFκB pathway PMCID:    Pubmed No.:30921699 MiR‐34a inhibits the proliferation, migration, and invasion of oral squamous cell carcinoma by directly targeting SATB2 PMCID:    Pubmed No.:31663131 Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice PMCID:    Pubmed No.:31988048 The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response PMCID:    Pubmed No.:29420297 Long Noncoding RNA NRAV Promotes Respiratory Syncytial Virus Replication by Targeting the MicroRNA miR-509-3p/Rab5c Axis To Regulate Vesicle Transportation PMCID:    Pubmed No.:32102886 Deficiency of the IRE1α-Autophagy Axis Enhances the Antitumor Effects of the Oncolytic Virus M1 PMCID:    Pubmed No.:29263275 Resolvin D1 Attenuates Innate Immune Reactions in Experimental Subarachnoid Hemorrhage Rat Model PMCID:    Pubmed No.:33411245 SIRT1 induces the adipogenic differentiation of mouse embryonic stem cells by regulating RA-induced RAR expression via NCOR1 acetylation PMCID:    Pubmed No.:32217463 m6A methyltransferase METTL3 promotes retinoblastoma progression via PI3K/AKT/mTOR pathway PMCID:    Pubmed No.:33090698 Ubiquitin‐specific protease 2 regulates Ang Ⅱ–induced cardiac fibroblasts activation by up‐regulating cyclin D1 and stabilizing β‐catenin in vitro PMCID:    Pubmed No.:33314748 Cistanche deserticola polysaccharide induces melanogenesis in melanocytes and reduces oxidative stress via activating NRF2/HO‐1 pathway PMCID:    Pubmed No.:32096914 Lentinan protects against pancreatic β‐cell failure in chronic ethanol consumption‐induced diabetic mice via enhancing β‐cell antioxidant capacity PMCID:    Pubmed No.:33837638 Zinc finger protein 91 loss induces cardiac hypertrophy through adenosine A1 receptor down‐regulation under pressure overload status PMCID:    Pubmed No.:32677376 IL‐27 Rα+ cells promoted allorejection via enhancing STAT1/3/5 phosphorylation PMCID:    Pubmed No.:32761753 LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway PMCID:    Pubmed No.:32881263 HIF‐1α‐induced up‐regulation of microRNA‐126 contributes to the effectiveness of exercise training on myocardial angiogenesis in myocardial infarction rats PMCID:    Pubmed No.:32939968 Alpha B‐crystallin promotes the invasion and metastasis of gastric cancer via NF‐κB‐induced epithelial‐mesenchymal transition PMCID:    Pubmed No.:29566309 ZAG alleviates HFD-induced insulin resistance accompanied with decreased lipid depot in skeletal muscle in mice PMCID:    Pubmed No.:30318474 Aging-Related Neural Disruption Might Predispose to Postoperative Cognitive Impairment Following Surgical Trauma PMCID:    Pubmed No.:33967044 CCNI2 plays a promoting role in the progression of colorectal cancer PMCID:    Pubmed No.:33620152 Flotillin-1 promotes progression and dampens chemosensitivity to cisplatin in gastric cancer via ERK and AKT signaling pathways PMCID:    Pubmed No.:34774850 The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway PMCID:    Pubmed No.:34425100 L-theanine inhibits foam cell formation via promoting the scavenger receptor A degradation PMCID:    Pubmed No.:34004205 Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy PMCID:    Pubmed No.:34087223 Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression PMCID:    Pubmed No.:30775800 Long noncoding RNA LINC00961 inhibits cell proliferation and induces cell apoptosis in human non–small cell lung cancer PMCID:    Pubmed No.:30010215 Polyglutamine protein in tumor cells sensitizes tumor cells to natural killer cell cytolysis PMCID:    Pubmed No.:32580073 Downregulating Heparanase-Induced Vascular Normalization: A New Approach To Increase the Bioavailability of Chemotherapeutics in Solid Tumors PMCID:    Pubmed No.:30059227 Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth PMCID:    Pubmed No.:32128976 Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements PMCID:    Pubmed No.:33446747 Histone Deacetylase Inhibitor Alleviates the Neurodegenerative Phenotypes and Histone Dysregulation in Presenilins-Deficient Mice PMCID:    Pubmed No.:29867447 Hydrogen sulfide attenuates oxidative stress-induced NLRP3 inflammasome activation via S-sulfhydrating c-Jun at Cys269 in macrophages PMCID:    Pubmed No.:29859240 Immune response in piglets orally immunized with recombinant Bacillus subtilis expressing the capsid protein of porcine circovirus type 2 PMCID:    Pubmed No.:32046726 Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice PMCID:    Pubmed No.:30797958 Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis PMCID:    Pubmed No.:29386287 The role of Snf5 in the osteogenic differentiation potential during replicative senescence of rat mesenchymal stromal cells PMCID:    Pubmed No.:29398003 Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor PMCID:    Pubmed No.:32018210 Rhein protects the myocardiac cells against hypoxia/reoxygention-induced injury by suppressing GSK3β activity PMCID:    Pubmed No.:30466606 Paeoniflorin modulates gut microbial production of indole-3-lactate and epithelial autophagy to alleviate colitis in mice PMCID:    Pubmed No.:33002829 Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation PMCID:    Pubmed No.:30700991 TRPC6 contributes to LPS-induced inflammation through ERK1/2 and p38 pathways in bronchial epithelial cells PMCID:    Pubmed No.:29141922 Adrenomedullin Receptors in Rats with Obesity-Related Hypertension PMCID:    Pubmed No.:30276527 Downregulation of long noncoding RNA SNHG1 inhibits cell proliferation, metastasis, and invasion by suppressing the Notch‐1 signaling pathway in pancreatic cancer PMCID:    Pubmed No.:30520072 Positive Effect of Andrographolide Induced Autophagy on Random-Pattern Skin Flaps Survival PMCID:    Pubmed No.:33796027 1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB PMCID:    Pubmed No.:30930772 Non-canonical Notch Signaling Regulates Actin Remodeling in Cell Migration by Activating PI3K/AKT/Cdc42 Pathway PMCID:    Pubmed No.:31057403
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
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