IL-17-triggered downregulation of miR-497 results in high HIF-1α expression and consequent IL-1β and IL-6 production by astrocytes in EAE mice PMCID:    Pubmed No.:28458392 Localized Delivery of shRNA against PHD2 Protects the Heart from Acute Myocardial Infarction through Ultrasound-Targeted Cationic Microbubble Destruction PMCID:    Pubmed No.:28042316 Norisoboldine, an Anti-Arthritis Alkaloid Isolated from Radix Linderae, Attenuates Osteoclast Differentiation and Inflammatory Bone Erosion in an Aryl Hydrocarbon Receptor-Dependent Manner PMCID:    Pubmed No.:26221077 MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R PMCID:    Pubmed No.:22073238 Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction PMCID:    Pubmed No.:22202974 MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1 PMCID:    Pubmed No.:22442669 MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas PMCID:    Pubmed No.:23431408 miR-21 Contributes to Xenon-conferred Amelioration of Renal Ischemia-Reperfusion Injury in Mice. PMCID:    Pubmed No.:23681145 Intratumor Hypoxia Promotes Immune Tolerance by Inducing Regulatory T Cells via TGF-β1 in Gastric Cancer PMCID:    Pubmed No.:23723999 Insulin Promotes Glucose Consumption via Regulation of miR-99a/mTOR/PKM2 Pathway PMCID:    Pubmed No.:23762265 Expression and significance of HIF-1α in pulmonary fibrosis induced by paraquat PMCID:    Pubmed No.:24048193 Transcatheter arterial embolization promotes liver tumor metastasis by increasing the population of circulating tumor cells PMCID:    Pubmed No.:24235842 Hypoxia-Inducible Factor-1α Dependent Pathways Mediate the Renoprotective Role of Acetazolamide Against Renal Ischemia-Reperfusion Injury PMCID:    Pubmed No.:None Hypoxia-Inducible Factor-1α Dependent Pathways Mediate the Renoprotective Role of Acetazolamide Against Renal Ischemia-Reperfusion Injury PMCID:    Pubmed No.:24335166 PES1 differentially regulates the expression of ERα and ERβ in ovarian cancer PMCID:    Pubmed No.:24376209 Overexpression of HIF-1α, metallothionein and SLUG is associated with high TNM stage and lymph node metastasis in papillary thyroid carcinoma PMCID:    Pubmed No.:24427353 Antiproliferative activity and therapeutic implications of potassium tris (4-methyl-1-pyrazolyl) borohydride in hepatocellular carcinoma PMCID:    Pubmed No.:24412237 PES1 differentially regulates the expression of ERα and ERβ in ovarian cancer PMCID:    Pubmed No.:24376209 Xuefuzhuyu decoction inhibition of angiogenesis attenuates liver fibrosis induced by CCl4 in mice PMCID:    Pubmed No.:24637190 Oroxylin A inhibits hypoxia-induced invasion and migration of MCF-7 cells by suppressing the Notch pathway PMCID:    Pubmed No.:24637576 Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells PMCID:    Pubmed No.:24779927 The effect of hyperbaric oxygen on intracephalic angiogenesis in rats with intracerebral hemorrhage PMCID:    Pubmed No.:24836574 MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras PMCID:    Pubmed No.:24861879 Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer PMCID:    Pubmed No.:25501705 The overexpression and nuclear translocation of Trx-1 during hypoxia confers HepG2 cells resistance to DDP and GL-V9 reverses the resistance by suppressing Trx-1/ref-1 axis. PMCID:    Pubmed No.:25656992 GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner PMCID:    Pubmed No.:25647524 GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ PMCID:    Pubmed No.:25748049 Pyruvate kinase M2 accelerates pro-inflammatory cytokine secretion and cell proliferation induced by lipopolysaccharide in colorectal cancer PMCID:    Pubmed No.:25778902 Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1 α/Stra13 pathway PMCID:    Pubmed No.:25801056 Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway. PMCID:    Pubmed No.:25801056 Norisoboldine, an Anti-Arthritis Alkaloid Isolated from Radix Linderae, Attenuates Osteoclast Differentiation and Inflammatory Bone Erosion in an Aryl Hydrocarbon Receptor-Dependent Manner. PMCID:    Pubmed No.:26221077 Ultrasound-Targeted Microbubble Destruction (UTMD) Assisted Delivery of shRNA against PHD2 into H9C2 Cells PMCID:    Pubmed No.:26267649 MiR-100 Inhibits Osteosarcoma Cell Proliferation, Migration, and Invasion and Enhances Chemosensitivity by Targeting IGFIR PMCID:    Pubmed No.:26306402 Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling PMCID:    Pubmed No.:26499200 Repression of PES1 expression inhibits growth of gastric cancer PMCID:    Pubmed No.:26423399 Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer PMCID:    Pubmed No.:25501705 TGF-β1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells PMCID:    Pubmed No.:26462837 Progesterone amplifies oxidative stress signal and promotes NO production via H 2 O 2 in mouse kidney arterial endothelial cells PMCID:    Pubmed No.:26462682 Preventive Effects of the Chinese Herbal Medicine Prescription Tangkuei Decoction for Frigid Extremities on Sciatic Neuropathy in Streptozotocin-Induced Diabetic Rats PMCID:    Pubmed No.:27057201 Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1a signaling axis PMCID:    Pubmed No.:26735336 Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer PMCID:    Pubmed No.:25501705 Transcatheter arterial embolization promotes liver tumor metastasis by increasing the population of circulating tumor cells PMCID:    Pubmed No.:24235842 Hypoxia-Inducible Factor-1α Dependent Pathways Mediate the Renoprotective Role of Acetazolamide Against Renal Ischemia-Reperfusion Injury PMCID:    Pubmed No.:None Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling PMCID:    Pubmed No.:26499200 Repression of PES1 expression inhibits growth of gastric cancer PMCID:    Pubmed No.:26423399 Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer PMCID:    Pubmed No.:25501705 TGF-β1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells PMCID:    Pubmed No.:26462837 Progesterone amplifies oxidative stress signal and promotes NO production via H 2 O 2 in mouse kidney arterial endothelial cells PMCID:    Pubmed No.:26462682 Preventive Effects of the Chinese Herbal Medicine Prescription Tangkuei Decoction for Frigid Extremities on Sciatic Neuropathy in Streptozotocin-Induced Diabetic Rats PMCID:    Pubmed No.:27057201 Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1a signaling axis PMCID:    Pubmed No.:26735336 Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells PMCID:    Pubmed No.:24779927 Hypoxia-Inducible Factor-1α Dependent Pathways Mediate the Renoprotective Role of Acetazolamide Against Renal Ischemia-Reperfusion Injury PMCID:    Pubmed No.:24335166 PES1 differentially regulates the expression of ERα and ERβ in ovarian cancer PMCID:    Pubmed No.:24376209 Overexpression of HIF-1α, metallothionein and SLUG is associated with high TNM stage and lymph node metastasis in papillary thyroid carcinoma PMCID:    Pubmed No.:24427353 Antiproliferative activity and therapeutic implications of potassium tris (4-methyl-1-pyrazolyl) borohydride in hepatocellular carcinoma PMCID:    Pubmed No.:24412237 PES1 differentially regulates the expression of ERα and ERβ in ovarian cancer PMCID:    Pubmed No.:24376209 Xuefuzhuyu decoction inhibition of angiogenesis attenuates liver fibrosis induced by CCl4 in mice PMCID:    Pubmed No.:24637190 Oroxylin A inhibits hypoxia-induced invasion and migration of MCF-7 cells by suppressing the Notch pathway PMCID:    Pubmed No.:24637576 DNA‐PKcs Deficiency Inhibits Glioblastoma Cell‐Derived Angiogenesis After Ionizing Radiation PMCID:    Pubmed No.:25294801 The role of the miR-31/FIH1 pathway in TGF-β-induced liver fibrosis PMCID:    Pubmed No.:25728779 Metformin inhibits gastric cancer via the inhibition of HIF1α/PKM2 signaling PMCID:    Pubmed No.:26101707 PRL-3 promotes gastric cancer migration and invasion through a NF-κB-HIF-1α-miR-210 axis PMCID:    Pubmed No.:26548949 A positive feedback loop promotes HIF‐1α stability through miR‐210‐mediated suppression of RUNX3 in paraquat‐induced EMT PMCID:    Pubmed No.:28699703 HIF‐1α regulates EMT via the Snail and β‐catenin pathways in paraquat poisoning‐induced early pulmonary fibrosis PMCID:    Pubmed No.:26781174 A novel nano-copper-bearing stainless steel with reduced Cu2+ release only inducing transient foreign body reaction via affecting the activity of NF-κB and Caspase 3 PMCID:    Pubmed No.:26604748 GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner PMCID:    Pubmed No.:25647524 Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling PMCID:    Pubmed No.:26499200 Hypoxia-induced and HIF1α-VEGF-mediated tight junction dysfunction in choriocarcinoma cells: Implications for preeclampsia PMCID:    Pubmed No.:29223764 Progesterone amplifies oxidative stress signal and promotes NO production via H2O2 in mouse kidney arterial endothelial cells PMCID:    Pubmed No.:26462682 GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ PMCID:    Pubmed No.:25748049 Ultrasound-Targeted Microbubble Destruction (UTMD) Assisted Delivery of shRNA against PHD2 into H9C2 Cells PMCID:    Pubmed No.:26267649 Curcumin inhibits hypoxia-induced proliferation and invasion of MG-63 osteosarcoma cells via downregulating Notch1 PMCID:    Pubmed No.:28138706 Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway PMCID:    Pubmed No.:25801056 Hypoxia-inducible factor-1α regulates epithelial-to-mesenchymal transition in paraquat-induced pulmonary fibrosis by activating lysyl oxidase PMCID:    Pubmed No.:29467842 MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells PMCID:    Pubmed No.:27765914 Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling PMCID:    Pubmed No.:27367023 MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer PMCID:    Pubmed No.:26989074 Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression PMCID:    Pubmed No.:27008697 Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer PMCID:    Pubmed No.:25501705 Repression of PES1 expression inhibits growth of gastric cancer PMCID:    Pubmed No.:26423399 TGF-β1 pathway affects the protein expression of many signaling pathways, markers of liver cancer stem cells, cytokeratins, and TERT in liver cancer HepG2 cells PMCID:    Pubmed No.:26462837 β2-Adrenogenic signaling regulates NNK-induced pancreatic cancer progression via upregulation of HIF-1α PMCID:    Pubmed No.:26497365 Original research: KALRN mutations promote antitumor immunity and immunotherapy response in cancer PMCID:    Pubmed No.:33037113 Myocardium-targeted transplantation of PHD2 shRNA-modified bone mesenchymal stem cells through ultrasound-targeted microbubble destruction protects the heart from acute myocardial infarction PMCID:    Pubmed No.:32308762 Anti-tumor effect of local injectable hydrogel-loaded endostatin alone and in combination with radiotherapy for lung cancer PMCID:    Pubmed No.:33427520 Influence of c-Src on hypoxic resistance to paclitaxel in human ovarian cancer cells and reversal of FV-429 PMCID:    Pubmed No.:29324735 Intratumoral Injection of Anlotinib Hydrogel Combined With Radiotherapy Reduces Hypoxia in Lewis Lung Carcinoma Xenografts: Assessment by Micro Fluorine-18-fluoromisonidazole Positron Emission Tomography/Computed Tomography Hypoxia Imaging PMCID:    Pubmed No.:33777779 Hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat (FG-4592) protects against cisplatin-induced acute kidney injury PMCID:    Pubmed No.:29581249 Hydrogen sulfide attenuates renal fibrosis by inducing TET‐dependent DNA demethylation on Klotho promoter PMCID:    Pubmed No.:32729950 Stabilized fermentation product of Cetobacterium somerae improves gut and liver health and antiviral immunity of zebrafish PMCID:    Pubmed No.:34780975 Oroxylin A increases the sensitivity of temozolomide on glioma cells by hypoxia‐inducible factor 1α/hedgehog pathway under hypoxia PMCID:    Pubmed No.:30790292 Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish PMCID:    Pubmed No.:31372513 Atorvastatin attenuates paraquat poisoning-induced epithelial-mesenchymal transition via downregulating hypoxia-inducible factor-1 alpha PMCID:    Pubmed No.:30336147 Inhibiting Succinate Dehydrogenase by Dimethyl Malonate Alleviates Brain Damage in a Rat Model of Cardiac Arrest PMCID:    Pubmed No.:30300703 Enhanced antitumor and anti-angiogenic effects of metronomic Vinorelbine combined with Endostar on Lewis lung carcinoma PMCID:    Pubmed No.:30305062 Activation of TGR5 restores AQP2 expression via the HIF pathway in renal ischemia-reperfusion injury PMCID:    Pubmed No.:33427060 Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway PMCID:    Pubmed No.:29328487 HIF‑1α promotes NLRP3 inflammasome activation in bleomycin‑induced acute lung injury PMCID:    Pubmed No.:31432144 Therapeutic Efficacy of Methazolamide Against Intermittent Hypoxia-Induced Excessive Erythrocytosis in Rats PMCID:    Pubmed No.:29077517 Roles Played by the PI3K/Akt/HIF-1α Pathway and IL-17A in the Chinese Subtype of Chronic Sinusitis with Nasal Polyps PMCID:    Pubmed No.:35075349 Crosstalk between IL-15Rα+ tumor-associated macrophages and breast cancer cells reduces CD8+ T cell recruitment PMCID:    Pubmed No.:35615815 Mechanism of Shiliu Buxue Syrup for anemia using integrated metabolomics and network pharmacology PMCID:    Pubmed No.:35690102 A Natural Gas Fermentation Bacterial Meal (FeedKind®) as a Functional Alternative Ingredient for Fishmeal in Diet of Largemouth Bass, Micropterus salmoides PMCID:    Pubmed No.:36009198 Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways PMCID:    Pubmed No.:37517820 Ginkgo biloba extract promotes Treg differentiation to ameliorate ischemic stroke via inhibition of HIF-1α/HK2 pathway PMCID:    Pubmed No.:37655539 The effect of stabilized culture of Lactobacillus rhamnosus GCC-3 on gut and liver health, and anti-viral immunity of zebrafish PMCID:    Pubmed No.:37714442