Product Name :
GAPDH (1A6) monoclonal antibody Background :
Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GAPDH (1A6) mAb detects endogenous levels of GAPDH protein. Immunogen :
Recombinant full length Human GAPDH. Conjugate :
Unconjugated Modification :
Unmodification
GAPDH (1A6) monoclonal antibody Background :
Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GAPDH (1A6) mAb detects endogenous levels of GAPDH protein. Immunogen :
Recombinant full length Human GAPDH. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of GAPDH (1A6) mAb at 1:20000/1:10000 dilution Lane1:L02 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:MG63 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Rat(40ug) Lane7:The Brain tissue lysate of Mouse(40ug)
-
Immunohistochemistry analyzes of GAPDH (1A6) antibody in paraffin-embedded human liver tissue
-
Immunohistochemistry analyzes of GAPDH (1A6) antibody in paraffin-embedded human liver tissue
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MicroRNA‑497 inhibits tumor growth through targeting insulin receptor substrate 1 in colorectal cancer
PMCID: Pubmed No.:29163678
Low‑level mechanical vibration enhances osteoblastogenesis via a canonical Wnt signaling‑associated mechanism
PMCID: Pubmed No.:28534995
Chrysin inhibits human airway smooth muscle cells proliferation through the extracellular signal‑regulated kinase 1/2 signaling pathway
PMCID: Pubmed No.:26502995
Hesperetin protects against inflammatory response and cardiac fibrosis in postmyocardial infarction mice by inhibiting nuclear factor κB signaling pathway
PMCID: Pubmed No.:28962151
Naringenin inhibits transforming growth factor‑β1‑induced cardiac fibroblast proliferation and collagen synthesis via G0/G1 arrest
PMCID: Pubmed No.:29104653
Naringenin attenuates pressure overload-induced cardiac hypertrophy
PMCID: Pubmed No.:26668617
Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway
PMCID: Pubmed No.:26722438
Cinnamaldehyde attenuates pressure overload-induced cardiac hypertrophy
PMCID: Pubmed No.:26823750
Myocardial apoptosis and injury of donor hearts kept in completely beating status with normothermic blood perfusion for transplants
PMCID: Pubmed No.:26131163
Danshen improves damaged cardiac angiogenesis and cardiac function induced by myocardial infarction by modulating HIF1α/VEGFA signaling pathway
PMCID: Pubmed No.:26770433
Puerarin accelerate scardiac angiogenesis and improves cardiac function of myocardial infarction by upregulating VEGFA, Ang-1 and Ang-2 in rats
PMCID: Pubmed No.:26885006
Role of microRNA-134 in the neuroprotective effects of propofol against oxygen-glucose deprivation and related mechanisms
PMCID: Pubmed No.:26884981
TES inhibits colorectal cancer progression through activation of p38
PMCID: Pubmed No.:27323777
Anti-angiogenic efficacy of 5′-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs
PMCID: Pubmed No.:26336994
The N-Degron Pathway Mediates ER-phagy
PMCID: Pubmed No.:31375263
The δ subunit of F1Fo-ATP synthase is required for pathogenicity of Candida albicans
PMCID: Pubmed No.:34654833
Exosomes with low miR-34c-3p expression promote invasion and migration of non-small cell lung cancer by upregulating integrin α2β1
PMCID: Pubmed No.:32317629
Injectable AuNP-HA matrix with localized stiffness enhances the formation of gap junction in engrafted human induced pluripotent stem cell-derived cardiomyocytes and promotes cardiac repair
PMCID: Pubmed No.:34739980
A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells
PMCID: Pubmed No.:30911006
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1
PMCID: Pubmed No.:33484341
Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer
PMCID: Pubmed No.:32248842
The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression
PMCID: Pubmed No.:31126313
Sirtuin 6 is a negative regulator of FcεRI signaling and anaphylactic responses
PMCID: Pubmed No.:34051221
Sirtuin 6 in preosteoclasts suppresses age- and estrogen deficiency-related bone loss by stabilizing estrogen receptor α
PMCID: Pubmed No.:30787391
Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer
PMCID: Pubmed No.:29685157
Cyclin B2 can compensate for Cyclin B1 in oocyte meiosis I
PMCID: Pubmed No.:30097513
Depletion of glioma stem cells by synergistic inhibition of mTOR and c-Myc with a biological camouflaged cascade brain-targeting nanosystem
PMCID: Pubmed No.:33296794
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK
PMCID: Pubmed No.:32283380
Sirt1-Overexpressing Mesenchymal Stem Cells Drive the Anti-tumor Effect through Their Pro-inflammatory Capacity
PMCID: Pubmed No.:32027844
CRISPR/Cas9-Mediated miR-29b Editing as a Treatment of Different Types of Muscle Atrophy in Mice
PMCID: Pubmed No.:32222157
A Novel mTORC1/2 Inhibitor (MTI-31) Inhibits Tumor Growth, Epithelial–Mesenchymal Transition, Metastases, and Improves Antitumor Immunity in Preclinical Models of Lung Cancer
PMCID: Pubmed No.:30796032
Controlling the Multiscale Network Structure of Fibers To Stimulate Wound Matrix Rebuilding by Fibroblast Differentiation
PMCID: Pubmed No.:31251577
Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis
PMCID: Pubmed No.:31541078
Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development
PMCID: Pubmed No.:33754063
Fusobacterium nucleatum Promotes Metastasis in Colorectal Cancer by Activating Autophagy Signaling via the Upregulation of CARD3 Expression
PMCID: Pubmed No.:31903123
SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride
PMCID: Pubmed No.:32308752
The anti-microbial peptide LL-37/CRAMP levels are associated with acute heart failure and can attenuate cardiac dysfunction in multiple preclinical models of heart failure
PMCID: Pubmed No.:32483446
Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma
PMCID: Pubmed No.:34815392
A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels
PMCID: Pubmed No.:33934099
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway
PMCID: Pubmed No.:34108447
miR-4293 upregulates lncRNA WFDC21P by suppressing mRNA-decapping enzyme 2 to promote lung carcinoma proliferation
PMCID: Pubmed No.:34301920
DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program
PMCID: Pubmed No.:31226106
HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury
PMCID: Pubmed No.:34666797
Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction
PMCID: Pubmed No.:34837851
Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake
PMCID: Pubmed No.:31534545
HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice
PMCID: Pubmed No.:32086291
Decreased Level of Exosomal miR-5121 Released from Microglia Suppresses Neurite Outgrowth and Synapse Recovery of Neurons Following Traumatic Brain Injury
PMCID: Pubmed No.:33475953
Interferon-Inducible LINC02605 Promotes Antiviral Innate Responses by Strengthening IRF3 Nuclear Translocation.
PMCID: Pubmed No.:34804040
Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation
PMCID: Pubmed No.:30980867
Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy
PMCID: Pubmed No.:30972284
Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway
PMCID: Pubmed No.:31783879
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b
PMCID: Pubmed No.:33614226
Fusobacterium nucleatum promotes M2 polarization of macrophages in the microenvironment of colorectal tumours via a TLR4-dependent mechanism
PMCID: Pubmed No.:30121899
SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury
PMCID: Pubmed No.:33854356
Biological and RNA regulatory function of MOV10 in mammalian germ cells
PMCID: Pubmed No.:31088452
PRRX1 deficiency induces mesenchymal‐epithelial transition through PITX2/miR‐200–dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma
PMCID: Pubmed No.:33587761
Functional recovery of a novel knockin mouse model of dysferlinopathy by readthrough of nonsense mutation
PMCID: Pubmed No.:34141825
Curculigoside Ameliorates Bone Loss by Influencing Mesenchymal Stem Cell Fate in Aging Mice.
PMCID: Pubmed No.:34926455
Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells
PMCID: Pubmed No.:34222256
Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination
PMCID: Pubmed No.:29353883
Tspan5 promotes epithelial–mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling
PMCID: Pubmed No.:33955149
Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation‐related signalling pathways
PMCID: Pubmed No.:31454852
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
PMCID: Pubmed No.:33867836
Dietary Protein From Different Sources Exerted a Great Impact on Lipid Metabolism and Mitochondrial Oxidative Phosphorylation in Rat Liver
PMCID: Pubmed No.:34513904
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism
PMCID: Pubmed No.:33250241
Cytotoxicity of hexabromocyclododecane, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane and 1,2,5,6-tetrabromocyclooctane in human SH-SY5Y neuroblastoma cells
PMCID: Pubmed No.:32758930
MICAL2 Contributes to Gastric Cancer Cell Proliferation by Promoting YAP Dephosphorylation and Nuclear Translocation
PMCID: Pubmed No.:34650666
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps
PMCID: Pubmed No.:33868571
Therapeutic evaluation of acupoint stimulation with needle-scapelon on rat model of degenerative cervical intervertebral discs
PMCID: Pubmed No.:30553194
Differential toxicities of triptolide to immortalized podocytes and the podocytes in vivo
PMCID: Pubmed No.:30551497
Post-transcription mediated Snail stabilization is involved in radiation exposure induced invasion and migration of hepatocarcinoma cells
PMCID: Pubmed No.:29684855
Photothermal and gene therapy combined with immunotherapy to gastric cancer by the gold nanoshell-based system
PMCID: Pubmed No.:31277667
Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents
PMCID: Pubmed No.:33933753
Deubiquitination and stabilization of estrogen receptor α by ubiquitin-specific protease 7 promotes breast tumorigenesis
PMCID: Pubmed No.:31518603
Long non-coding RNA MCM3AP-AS1 promotes growth and migration through modulating FOXK1 by sponging miR-138-5p in pancreatic cancer
PMCID: Pubmed No.:31830901
HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models
PMCID: Pubmed No.:29113455
ALKBH5 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating PTEN expression in an m6A-dependent manner
PMCID: Pubmed No.:34438274
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse
PMCID: Pubmed No.:34695613
Circ-SHPRH suppresses cadmium-induced transformation of human bronchial epithelial cells by regulating QKI expression via miR-224–5p
PMCID: Pubmed No.:34082244
TRPV3 enhances skin keratinocyte proliferation through EGFR-dependent signaling pathways
PMCID: Pubmed No.:32535744
Hypoxia-Induced miR-137 Inhibition Increased Glioblastoma Multiforme Growth and Chemoresistance Through LRP6
PMCID: Pubmed No.:33718112
Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer
PMCID: Pubmed No.:33968724
S-nitrosylation of c-Jun N-terminal kinase mediates pressure overload-induced cardiac dysfunction and fibrosis
PMCID: Pubmed No.:34011968
Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer
PMCID: Pubmed No.:30250021
Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy
PMCID: Pubmed No.:35509816
Riboflavin deficiency affects lipid metabolism partly by reducing apolipoprotein B100 synthesis in rats
PMCID: Pubmed No.:31176989
Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis
PMCID: Pubmed No.:31189885
Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement
PMCID: Pubmed No.:31522191
Regulatory roles of miR-22/Redd1-mediated mitochondrial ROS and cellular autophagy in ionizing radiation-induced BMSC injury
PMCID: Pubmed No.:30846680
A miR-125b/CSF1-CX3CL1/tumor-associated macrophage recruitment axis controls testicular germ cell tumor growth
PMCID: Pubmed No.:30237497
miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma
PMCID: Pubmed No.:29531296
miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma
PMCID: Pubmed No.:29531296
LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis
PMCID: Pubmed No.:31982491
Scutellarin, a modulator of mTOR, attenuates hepatic insulin resistance by regulating hepatocyte lipid metabolism via SREBP-1c suppression
PMCID: Pubmed No.:31828866
Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway
PMCID: Pubmed No.:34859513
Fusobacterium nucleatum Activates Endoplasmic Reticulum Stress to Promote Crohn’s Disease Development via the Upregulation of CARD3 Expression
PMCID: Pubmed No.:32153411
Combined Treatment With 2-(2-Benzofu-Ranyl)-2-Imidazoline and Recombinant Tissue Plasminogen Activator Protects Blood–Brain Barrier Integrity in a Rat Model of Embolic Middle Cerebral Artery Occlusion
PMCID: Pubmed No.:32595494
Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer
PMCID: Pubmed No.:34305593
A Single, Acute Astragaloside IV Therapy Protects Cardiomyocyte Through Attenuating Superoxide Anion-Mediated Accumulation of Autophagosomes in Myocardial Ischemia-Reperfusion Injury
PMCID: Pubmed No.:34349641
Targeting aerobic glycolysis by dichloroacetate improves Newcastle disease virus-mediated viro-immunotherapy in hepatocellular carcinoma
PMCID: Pubmed No.:31819179
NLRP3 Inflammasome-Dependent Increases in High Mobility Group Box 1 Involved in the Cognitive Dysfunction Caused by Tau-Overexpression
PMCID: Pubmed No.:34539383
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children
PMCID: Pubmed No.:30659323
A new gold(I) complex-Au(PPh3)PT is a deubiquitinase inhibitor and inhibits tumor growth
PMCID: Pubmed No.:30527624
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth
PMCID: Pubmed No.:34774047
RPL35A is a key promotor involved in the development and progression of gastric cancer
PMCID: Pubmed No.:34535139
Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo
PMCID: Pubmed No.:33931059
CircRNA NALCN acts as an miR-493-3p sponge to regulate PTEN expression and inhibit glioma progression
PMCID: Pubmed No.:34112159
HOXB7 acts as an oncogenic biomarker in head and neck squamous cell carcinoma
PMCID: Pubmed No.:34303375
Fludarabine as an Adjuvant Improves Newcastle Disease Virus-Mediated Antitumor Immunity in Hepatocellular Carcinoma
PMCID: Pubmed No.:31011625
Suppression of CCDC6 sensitizes tumor to oncolytic virus M1
PMCID: Pubmed No.:33338804
Conditional deletion of Wntless in granulosa cells causes impaired corpora lutea formation and subfertility
PMCID: Pubmed No.:33291079
Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice
PMCID: Pubmed No.:31048563
Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer
PMCID: Pubmed No.:34623971
Near-infrared light-activatable siRNA delivery by microcapsules for combined tumour therapy
PMCID: Pubmed No.:29527926
Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway
PMCID: Pubmed No.:31234944
Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide
PMCID: Pubmed No.:31126320
MicroRNA-663 facilitates the growth, migration and invasion of ovarian cancer cell by inhibiting TUSC2
PMCID: Pubmed No.:30944041
Glycochenodeoxycholate promotes the metastasis of gallbladder cancer cells by inducing epithelial to mesenchymal transition via activation of SOCS3/JAK2/STAT3 signaling pathway
PMCID: Pubmed No.:31347168
Dynamic recognition and repair of DNA complex damage
PMCID: Pubmed No.:30537094
Phosphoinositide 3‐kinase/protein kinase B inhibition restores regulatory T cell's function in pulmonary sarcoidosis
PMCID: Pubmed No.:30945303
Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy
PMCID: Pubmed No.:30585174
Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes
PMCID: Pubmed No.:31028245
Osterix regulates corticalization for longitudinal bone growth via integrin β3 expression
PMCID: Pubmed No.:30022046
Autophagy Activation is Associated with Neuroprotection in Diabetes-associated Cognitive Decline
PMCID: Pubmed No.:31788335
Involvement of the MiR-181b-5p/HMGB1 Pathway in Ang II-induced Phenotypic Transformation of Smooth Muscle Cells in Hypertension
PMCID: Pubmed No.:31011475
Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility
PMCID: Pubmed No.:31005715
A-kinase-interacting protein 1 facilitates growth and metastasis of gastric cancer cells via Slug-induced epithelial-mesenchymal transition
PMCID: Pubmed No.:31020809
Lactobacillus Protects Against S. Typhimurium–Induced Intestinal Inflammation by Determining the Fate of Epithelial Proliferation and Differentiation
PMCID: Pubmed No.:31953989
Fecal Microbiota Transplantation Protects the Intestinal Mucosal Barrier by Reconstructing the Gut Microbiota in a Murine Model of Sepsis
PMCID: Pubmed No.:34631604
LncRNA ENSMUST00000155383 is Involved in the Improvement of DPP-4 Inhibitor MK-626 on Vascular Endothelial Function by Modulating Cacna1c-Mediated Ca2+ Influx in Hypertensive Mice
PMCID: Pubmed No.:34368236
MicroRNA‐219 decreases hippocampal long‐term potentiation inhibition and hippocampal neuronal cell apoptosis in type 2 diabetes mellitus mice by suppressing the NMDAR signaling pathway
PMCID: Pubmed No.:29804319
Insulin-like growth factor binding protein-1 regulates HIF-1α degradation to inhibit apoptosis in hypoxic cardiomyocytes
PMCID: Pubmed No.:34531382
c-Myc Is a Major Determinant for Antitumor Activity of Aurora A Kinase Inhibitor MLN8237 in Thyroid Cancer
PMCID: Pubmed No.:30226440
The Krüppel-like factor 15-NFATc1 axis ameliorates podocyte injury: a novel rationale for using glucocorticoids in proteinuria diseases
PMCID: Pubmed No.:32478397
Mindin deficiency in macrophages protects against foam cell formation and atherosclerosis by targeting LXR-β
PMCID: Pubmed No.:29695588
Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Random Skin Flaps via ROS Elimination
PMCID: Pubmed No.:33898433
Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A–Smad2/3 in rats following myocardial infarction
PMCID: Pubmed No.:33932887
Dysregulation of UDP-glucuronosyltransferases in CCl4 induced liver injury rats
PMCID: Pubmed No.:32380060
The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply
PMCID: Pubmed No.:31425655
Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR-miR-429 pathway
PMCID: Pubmed No.:33811696
Follicular fluid exosomes: Important modulator in proliferation and steroid synthesis of porcine granulosa cells
PMCID: Pubmed No.:33908671
ERα is a target for butein-induced growth suppression in breast cancer
PMCID: Pubmed No.:33294263
KLK11 suppresses cellular proliferation via inhibition of Wnt/β-catenin signaling pathway in esophageal squamous cell carcinoma
PMCID: Pubmed No.:31720087
Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis
PMCID: Pubmed No.:31718671
Circ_0088194 Promotes the Invasion and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the miR-766-3p/MMP2 Axis
PMCID: Pubmed No.:33692802
Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats
PMCID: Pubmed No.:31827689
Farrerol Directly Targets GSK-3β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries
PMCID: Pubmed No.:32082480
Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits
PMCID: Pubmed No.:32685087
Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression
PMCID: Pubmed No.:30150788
Isoflavones enhance pharmacokinetic exposure of active lovastatin acid via the upregulation of carboxylesterase in high-fat diet mice after oral administration of Xuezhikang capsules
PMCID: Pubmed No.:29921884
Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor
PMCID: Pubmed No.:33820450
Long noncoding RNA HOTAIR promotes renal cell carcinoma malignancy through alpha‐2, 8‐sialyltransferase 4 by sponging microRNA‐124
PMCID: Pubmed No.:30105850
Silent information regulator 1 suppresses epithelial-to-mesenchymal transition in lung cancer cells via its regulation of mitochondria status
PMCID: Pubmed No.:34119539
Proteomes analysis reveals the involvement of autophagy in AD-like neuropathology induced by noise exposure and ApoE4
PMCID: Pubmed No.:31228807
The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome
PMCID: Pubmed No.:31914678
Pharmacological activation of ERβ by arctigenin maintains the integrity of intestinal epithelial barrier in inflammatory bowel diseases
PMCID: Pubmed No.:31908053
The opposite functions of miR‐24 in the osteogenesis and adipogenesis of adipose‐derived mesenchymal stem cells are mediated by the HOXB7/β‐catenin complex
PMCID: Pubmed No.:32413244
The levels and significance of inflammasomes in the mouse retina following optic nerve crush
PMCID: Pubmed No.:30939414
Ulinastatin mediates suppression of regulatory T cells through TLR4/NF-κB signaling pathway in murine sepsis
PMCID: Pubmed No.:30261464
mTOR- and SGK-Mediated Connexin 43 Expression Participates in Lipopolysaccharide-Stimulated Macrophage Migration through the iNOS/Src/FAK Axis
PMCID: Pubmed No.:30341186
Serum- and glucocorticoid-inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1
PMCID: Pubmed No.:33724645
l-Theanine attenuates neointimal hyperplasia via suppression of vascular smooth muscle cell phenotypic modulation
PMCID: Pubmed No.:32402912
ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway
PMCID: Pubmed No.:31281585
RRM2 is a potential prognostic biomarker with functional significance in glioma
PMCID: Pubmed No.:30745840
Knockdown of Kremen2 Inhibits Tumor Growth and Migration in Gastric Cancer
PMCID: Pubmed No.:33489867
Downregulation of miR-22 Contributes to Epithelial-Mesenchymal Transition in Osteosarcoma by Targeting Twist1
PMCID: Pubmed No.:32391253
Discovery of coumarin-derived imino sulfonates as a novel class of potential cardioprotective agents
PMCID: Pubmed No.:31629165
Reduced miR-203 predicts metastasis and poor survival in esophageal carcinoma
PMCID: Pubmed No.:31844033
β-arrestin2 alleviates L-dopa–induced dyskinesia via lower D1R activity in Parkinson’s rats
PMCID: Pubmed No.:31891566
TYRO3 facilitates cell growth and metastasis via activation of the Wnt/β-catenin signaling pathway in human gastric cancer cells
PMCID: Pubmed No.:32018224
Protective effects of ginseng stem-leaf saponins on D-galactose-induced reproductive injury in male mice
PMCID: Pubmed No.:33714944
Resveratrol represses estrogen-induced mammary carcinogenesis through NRF2-UGT1A8-estrogen metabolic axis activation
PMCID: Pubmed No.:30009768
A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan
PMCID: Pubmed No.:30733972
Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice
PMCID: Pubmed No.:30946910
CircSPAG16 suppresses cadmium-induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt
PMCID: Pubmed No.:34081812
GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner
PMCID: Pubmed No.:31324725
A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway
PMCID: Pubmed No.:31396207
Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses
PMCID: Pubmed No.:30333836
A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis
PMCID: Pubmed No.:30425719
Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats
PMCID: Pubmed No.:32084453
Clinopodium chinense Attenuates Palmitic Acid-Induced Vascular Endothelial Inflammation and Insulin Resistance through TLR4-Mediated NF-κB and MAPK Pathways
PMCID: Pubmed No.:30776912
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS‐G12D mutation and P53 knockout
PMCID: Pubmed No.:31410985
Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK‐ERK pathway
PMCID: Pubmed No.:30907511
Overexpression of ZEB2‐AS1 promotes epithelial‐to‐mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma
PMCID: Pubmed No.:30950191
MICAL1 facilitates breast cancer cell proliferation via ROS‐sensitive ERK/cyclin D pathway
PMCID: Pubmed No.:29524295
AR-mTOR-SRF Axis Regulates HMMR Expression in Human Prostate Cancer Cells
PMCID: Pubmed No.:34099592
Galectin-3 Interacts with C/EBPβ and Upregulates Hyaluronan-Mediated Motility Receptor Expression in Gastric Cancer
PMCID: Pubmed No.:31822520
NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity
PMCID: Pubmed No.:32805187
Mechanical Strain Regulates Myofibroblast Differentiation of Human Scleral Fibroblasts by YAP
PMCID: Pubmed No.:34658907
OCT4B-190 protects against ischemic stroke by modulating GSK-3β/HDAC6
PMCID: Pubmed No.:30981804
Sodium-glucose co-transporter-2 (SGLT-2) inhibition reduces glucose uptake to induce breast cancer cell growth arrest through AMPK/mTOR pathway
PMCID: Pubmed No.:33068934
Rhodiola crenulata root extract ameliorates fructose-induced hepatic steatosis in rats: Association with activating autophagy
PMCID: Pubmed No.:32007914
Synergistic antitumour effects of triptolide plus 10-hydroxycamptothecin onbladder cancer
PMCID: Pubmed No.:31063955
PM2.5 promotes plaque vulnerability at different stages of atherosclerosis and the formation of foam cells via TLR4/MyD88/NFκB pathway
PMCID: Pubmed No.:30921699
MiR‐34a inhibits the proliferation, migration, and invasion of oral squamous cell carcinoma by directly targeting SATB2
PMCID: Pubmed No.:31663131
Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice
PMCID: Pubmed No.:31988048
Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer’s Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2
PMCID: Pubmed No.:32737764
SIRT1 induces the adipogenic differentiation of mouse embryonic stem cells by regulating RA-induced RAR expression via NCOR1 acetylation
PMCID: Pubmed No.:32217463
m6A methyltransferase METTL3 promotes retinoblastoma progression via PI3K/AKT/mTOR pathway
PMCID: Pubmed No.:33090698
Ubiquitin‐specific protease 2 regulates Ang Ⅱ–induced cardiac fibroblasts activation by up‐regulating cyclin D1 and stabilizing β‐catenin in vitro
PMCID: Pubmed No.:33314748
Inhibition of USP14 suppresses the formation of foam cell by promoting CD36 degradation
PMCID: Pubmed No.:31970862
Cistanche deserticola polysaccharide induces melanogenesis in melanocytes and reduces oxidative stress via activating NRF2/HO‐1 pathway
PMCID: Pubmed No.:32096914
Lentinan protects against pancreatic β‐cell failure in chronic ethanol consumption‐induced diabetic mice via enhancing β‐cell antioxidant capacity
PMCID: Pubmed No.:33837638
Alpha B‐crystallin promotes the invasion and metastasis of gastric cancer via NF‐κB‐induced epithelial‐mesenchymal transition
PMCID: Pubmed No.:29566309
Aging-Related Neural Disruption Might Predispose to Postoperative Cognitive Impairment Following Surgical Trauma
PMCID: Pubmed No.:33967044
The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway
PMCID: Pubmed No.:34425100
L-theanine inhibits foam cell formation via promoting the scavenger receptor A degradation
PMCID: Pubmed No.:34004205
Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression
PMCID: Pubmed No.:30775800
Long noncoding RNA LINC00961 inhibits cell proliferation and induces cell apoptosis in human non–small cell lung cancer
PMCID: Pubmed No.:30010215
Polyglutamine protein in tumor cells sensitizes tumor cells to natural killer cell cytolysis
PMCID: Pubmed No.:32580073
Downregulating Heparanase-Induced Vascular Normalization: A New Approach To Increase the Bioavailability of Chemotherapeutics in Solid Tumors
PMCID: Pubmed No.:30059227
Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth
PMCID: Pubmed No.:32128976
Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements
PMCID: Pubmed No.:33446747
The expression of ATP-sensitive potassium channels in human umbilical arteries with severe pre-eclampsia
PMCID: Pubmed No.:33846486
Histone Deacetylase Inhibitor Alleviates the Neurodegenerative Phenotypes and Histone Dysregulation in Presenilins-Deficient Mice
PMCID: Pubmed No.:29867447
Immune response in piglets orally immunized with recombinant Bacillus subtilis expressing the capsid protein of porcine circovirus type 2
PMCID: Pubmed No.:32046726
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice
PMCID: Pubmed No.:30797958
Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor
PMCID: Pubmed No.:32018210
Rhein protects the myocardiac cells against hypoxia/reoxygention-induced injury by suppressing GSK3β activity
PMCID: Pubmed No.:30466606
Quercetin and kaempferol increase the intestinal absorption of isorhamnetin coexisting in Elaeagnus rhamnoides (L.) A. Nelson (Elaeagnaceae) extracts via regulating multidrug resistance-associated protein 2
PMCID: Pubmed No.:30668394
Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation
PMCID: Pubmed No.:30700991
Adrenomedullin Receptors in Rats with Obesity-Related Hypertension
PMCID: Pubmed No.:30276527
Downregulation of long noncoding RNA SNHG1 inhibits cell proliferation, metastasis, and invasion by suppressing the Notch‐1 signaling pathway in pancreatic cancer
PMCID: Pubmed No.:30520072
1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB
PMCID: Pubmed No.:30930772
YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways
PMCID: Pubmed No.:31031629
WNT7A Promotes EGF-Induced Migration of Oral Squamous Cell Carcinoma Cells by Activating β-Catenin/MMP9-Mediated Signaling
PMCID: Pubmed No.:32174831
Protective Effects of the Soluble Epoxide Hydrolase Inhibitor 1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea in a Rat Model of Permanent Middle Cerebral Artery Occlusion
PMCID: Pubmed No.:32184732
Tanshinone IIA Suppresses Proliferation and Inflammatory Cytokine Production of Synovial Fibroblasts from Rheumatoid Arthritis Patients Induced by TNF-α and Attenuates the Inflammatory Response in AIA Mice
PMCID: Pubmed No.:32499694
Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways
PMCID: Pubmed No.:32719603
Qianlie Xiaozheng Decoction Induces Autophagy in Human Prostate Cancer Cells via Inhibition of the Akt/mTOR Pathway
PMCID: Pubmed No.:29670523
Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses
PMCID: Pubmed No.:34755645
Inhibition of p22phox Suppresses Epithelial Ovarian Cancer Cell Proliferation and Tumorigenesis
PMCID: Pubmed No.:34093828
Curcumin enhances cisplatin sensitivity of human NSCLC cell lines through influencing Cu-Sp1-CTR1 regulatory loop
PMCID: Pubmed No.:30195880
Rosiglitazone metformin adduct inhibits hepatocellular carcinoma proliferation via activation of AMPK/p21 pathway
PMCID: Pubmed No.:30651718
GNG5 is a novel oncogene associated with cell migration, proliferation, and poor prognosis in glioma
PMCID: Pubmed No.:34098960
MYOD1 inhibits avian adipocyte differentiation via miRNA-206/ KLF4 axis
PMCID: Pubmed No.:33952351
Inhibitory Effects of Periplocin on Lymphoma Cells: A Network Pharmacology Approach and Experimental Validation
PMCID: Pubmed No.:33814899
Bilayered PLGA/PLGA-HAp Composite Scaffold for Osteochondral Tissue Engineering and Tissue Regeneration
PMCID: Pubmed No.:33465902
Proximity ligation assay mediated rolling circle amplification strategy for in situ amplified imaging of glycosylated PD-L1
PMCID: Pubmed No.:34523014
Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats
PMCID: Pubmed No.:31391086
Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis
PMCID: Pubmed No.:32066482
CD8 + T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma
PMCID: Pubmed No.:29784005
Fusobacterium nucleatum Promotes the Development of Ulcerative Colitis by Inducing the Autophagic Cell Death of Intestinal Epithelial
PMCID: Pubmed No.:33330137
PM2.5 induces endothelial dysfunction via activating NLRP3 inflammasome
PMCID: Pubmed No.:34173703
Periodontitis-level butyrate-induced ferroptosis in periodontal ligament fibroblasts by activation of ferritinophagy
PMCID: Pubmed No.:33298848
Resveratrol inhibits bile acid‐induced gastric intestinal metaplasia via the PI3K/AKT/p‐FoxO4 signalling pathway
PMCID: Pubmed No.:33103284
dl‐3‐n‐butylphthalide preserves white matter integrity and alleviates cognitive impairment in mice with chronic cerebral hypoperfusion
PMCID: Pubmed No.:31334611
LncRNA PICART1 suppressed non-small cell lung cancer cells proliferation and invasion by targeting AKT1 signaling pathway
PMCID: Pubmed No.:30662662
A Ce(III) complex potently inhibits the activity and expression of tyrosine phosphatase SHP-2
PMCID: Pubmed No.:31763642
Enrichment of cancer stem cells by agarose multi-well dishes and 3D spheroid culture
PMCID: Pubmed No.:30244317
Radix et Rhizoma Ginseng chemoprevents both initiation and promotion of cutaneous carcinoma by enhancing cell-mediated immunity and maintaining redox homeostasis
PMCID: Pubmed No.:32617038
Combination of chick embryo and nutrient mixture prevent D-galactose-induced cognitive deficits, immune impairment and oxidative stress in aging rat model
PMCID: Pubmed No.:30858562
Calretinin Participates in Regulating Steroidogenesis by PLC-Ca 2+ -PKC Pathway in Leydig Cells
PMCID: Pubmed No.:29743498
Chronic noise exposure exacerbates AD-like neuropathology in SAMP8 mice in relation to Wnt signaling in the PFC and hippocampus
PMCID: Pubmed No.:30279527
Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression
PMCID: Pubmed No.:31758083
The positive effect of chick embryo and nutrient mixture on bone marrow- derived mesenchymal stem cells from aging rats
PMCID: Pubmed No.:29728592
Enhancement of adenovirus infection and adenoviral vector-mediated gene delivery by bromodomain inhibitor JQ1
PMCID: Pubmed No.:30068949
Striatal overexpression of β-arrestin2 counteracts L-dopa-induced dyskinesia in 6-hydroxydopamine lesioned Parkinson's disease rats
PMCID: Pubmed No.:31491493
Akt phosphorylation regulated by IKKε in response to low shear stress leads to endothelial inflammation via activating IRF3
PMCID: Pubmed No.:33370582
Resveratrol alleviates oxidative stress caused by Streptococcus uberis infection via activating the Nrf2 signaling pathway
PMCID: Pubmed No.:33045565
UUO induces lung fibrosis with macrophage-myofibroblast transition in rats
PMCID: Pubmed No.:33540244
Lipoxin A4 reduces hyperoxia-induced lung injury in neonatal rats through PINK1 signaling pathway
PMCID: Pubmed No.:31152979
Interleukin 33 ameliorates disturbance of regulatory T cells in pulmonary sarcoidosis
PMCID: Pubmed No.:30195819
Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway
PMCID: Pubmed No.:32513156
Upregulation of Twist is involved in Gli1 induced migration and invasion of hepatocarcinoma cells
PMCID: Pubmed No.:29908118
Muscone Ameliorates Synaptic Dysfunction and Cognitive Deficits in APP/PS1 Mice
PMCID: Pubmed No.:32538849
Radiation Induces Apoptosis and Osteogenic Impairment through miR-22-Mediated Intracellular Oxidative Stress in Bone Marrow Mesenchymal Stem Cells
PMCID: Pubmed No.:30158985
Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy
PMCID: Pubmed No.:31926197
CTRP9 alleviates foam cells apoptosis by enhancing cholesterol efflux
PMCID: Pubmed No.:33352225
FOXE1 inhibits cell proliferation, migration and invasion of papillary thyroid cancer by regulating PDGFA
PMCID: Pubmed No.:31129275
Depletion of Microglia Attenuates Dendritic Spine Loss and Neuronal Apoptosis in the Acute Stage of Moderate Traumatic Brain Injury in Mice
PMCID: Pubmed No.:31397209
A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury
PMCID: Pubmed No.:31467487
Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase
PMCID: Pubmed No.:32508525
Effects of chronic stress on depressive-like behaviors and JMJD3 expression in the prefrontal cortex and hippocampus of C57BL/6 and ob/ob mice
PMCID: Pubmed No.:33340793
PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice
PMCID: Pubmed No.:29800919
Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma
PMCID: Pubmed No.:30021341
The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma
PMCID: Pubmed No.:29574282
MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer
PMCID: Pubmed No.:29567542
The Cellular Senescence-Inhibited Gene Is Essential for PPM1A Myristoylation To Modulate Transforming Growth Factor β Signaling
PMCID: Pubmed No.:30201805
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice
PMCID: Pubmed No.:32581664
Scutellarin ameliorates high glucose-induced vascular endothelial cells injury by activating PINK1/Parkin-mediated mitophagy
PMCID: Pubmed No.:33485979
miR-19b-3p promotes human pancreatic cancer Capan-2 cells proliferation by targeting phosphatase and tension homolog
PMCID: Pubmed No.:31317006
Embryonic morphology observation and HOXC8 gene expression in crest cushions of Chinese Crested duck
PMCID: Pubmed No.:30529099
Exogenous hydrogen sulfide prevents lipopolysaccharide-induced inflammation by blocking the TLR4/NF-κB pathway in MAC-T cells
PMCID: Pubmed No.:31153885
Transcriptome analysis of the hippocampus in environmental noise-exposed SAMP8 mice reveals regulatory pathways associated with Alzheimer’s disease neuropathology
PMCID: Pubmed No.:31918655
Ursolic acid induces apoptosis and anoikis in colorectal carcinoma RKO cells
PMCID: Pubmed No.:33549076
Myrtenal and β-caryophyllene oxide screened from Liquidambaris Fructus suppress NLRP3 inflammasome components in rheumatoid arthritis
PMCID: Pubmed No.:34583676
Icariin Attenuates M1 Activation of Microglia and Aβ Plaque Accumulation in the Hippocampus and Prefrontal Cortex by Up-Regulating PPARγ in Restraint/Isolation-Stressed APP/PS1 Mice
PMCID: Pubmed No.:31001073
PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration
PMCID: Pubmed No.:33181174
The in vitro effects of phospholipase D1-mTOR axis in liver fibrogenesis
PMCID: Pubmed No.:32240681
CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection
PMCID: Pubmed No.:33223223
Up-regulation of PTEN via LPS/AP-1/NF-κB pathway inhibits trophoblast invasion contributing to preeclampsia
PMCID: Pubmed No.:31896494
The possible molecular mechanisms of farnesol on the antifungal resistance of C. albicans biofilms: the regulation of CYR1 and PDE2
PMCID: Pubmed No.:30509171
Dl-3-N-Butylphthalide Alleviates the Blood–Brain Barrier Permeability of Focal Cerebral Ischemia Reperfusion in Mice
PMCID: Pubmed No.:31247236
A novel oleanolic acid derivative HA-19 ameliorates muscle atrophy via promoting protein synthesis and preventing protein degradation
PMCID: Pubmed No.:31201822
Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats
PMCID: Pubmed No.:29729281
Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells
PMCID: Pubmed No.:29609003
Induction of apoptosis in hematological cancer cells by dorsomorphin correlates with BAD upregulation
PMCID: Pubmed No.:31787232
CDK5 Functions as a Tumor Promoter in Human Lung Cancer
PMCID: Pubmed No.:30410599
Pristimerin induces apoptosis and inhibits proliferation, migration in H1299 Lung Cancer Cells
PMCID: Pubmed No.:33033518
Liraglutide activates nature killer cell-mediated antitumor responses by inhibiting IL-6/STAT3 signaling in hepatocellular carcinoma
PMCID: Pubmed No.:32979685
Downregulation of TNF-α/TNF-R1 Signals by AT-Lipoxin A4 May Be a Significant Mechanism of Attenuation in SAP-Associated Lung Injury
PMCID: Pubmed No.:31097921
miR-486 Promotes Capan-2 Pancreatic Cancer Cell Proliferation by Targeting Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)
PMCID: Pubmed No.:31258546
Different effects of anti-VEGF drugs (Ranibizumab, Aflibercept, Conbercept) on autophagy and its effect on neovascularization in RF/6A cells
PMCID: Pubmed No.:34119535
FABP4 accelerates glioblastoma cell growth and metastasis through Wnt10b signalling.
PMCID: Pubmed No.:30536325
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition
PMCID: Pubmed No.:30826420
Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat
PMCID: Pubmed No.:30172000
Diminished CD68+ Cancer-Associated Fibroblast Subset Induces Regulatory T-Cell (Treg) Infiltration and Predicts Poor Prognosis of Oral Squamous Cell Carcinoma Patients
PMCID: Pubmed No.:32035062
Mechanical Strain Induces Distinct Human Scleral Fibroblast Lineages: Differential Roles in Cell Proliferation, Apoptosis, Migration, and Differentiation
PMCID: Pubmed No.:29847646
Gastric-cancer-derived mesenchymal stem cells: a promising target for resveratrol in the suppression of gastric cancer metastasis
PMCID: Pubmed No.:32350750
Sorting nexin 11 knockout mice exhibit enhanced thermosensing behaviour
PMCID: Pubmed No.:31730264
Hypoxia‐induced ARHGAP26 deficiency inhibits the proliferation and migration of human ductus arteriosus smooth muscle cell through activating RhoA‐ROCK‐PTEN pathway
PMCID: Pubmed No.:30592323
The effects of parathyroid hormone‐related peptide on cardiac angiogenesis, apoptosis, and function in mice with myocardial infarction
PMCID: Pubmed No.:30994964
Xiao Ke Qing improves glycometabolism and ameliorates insulin resistance by regulating the PI3K/Akt pathway in KKAy mice
PMCID: Pubmed No.:30421394
Costunolide induces apoptosis and inhibits migration and invasion in H1299 lung cancer cells
PMCID: Pubmed No.:32236584
Ribes diacanthum Pall (RDP) ameliorates UUO-induced renal fibrosis via both canonical and non-canonical TGF-β signaling pathways in mice
PMCID: Pubmed No.:30342194
PCB118 Induces Inflammation of Islet Beta Cells via Activating ROS-NLRP3 Inflammasome Signaling
PMCID: Pubmed No.:34055976
Gene expression in human umbilical vein endothelial cells exposed to fine particulate matter: RNA sequencing analysis
PMCID: Pubmed No.:34102927
Amyloid-β1-42 dynamically regulates the migration of neural stem/progenitor cells via MAPK-ERK pathway
PMCID: Pubmed No.:30399361
Inhibition of DNMT suppresses the stemness of colorectal cancer cells through down-regulating Wnt signaling pathway
PMCID: Pubmed No.:29601907
HASPIN is involved in the progression of gallbladder carcinoma
PMCID: Pubmed No.:31987787
Knockdown of ALPK2 blocks development and progression of renal cell carcinoma
PMCID: Pubmed No.:32330508
Mitoferrin 2 deficiency prevents mitochondrial iron overload-induced endothelial injury and alleviates atherosclerosis
PMCID: Pubmed No.:33711329
Babaodan inhibits cell growth by inducing autophagy through the PI3K/AKT/mTOR pathway and enhances antitumor effects of cisplatin in NSCLC cells
PMCID: Pubmed No.:31497240
Trimethylamine N-Oxide Exacerbates Cardiac Fibrosis via Activating the NLRP3 Inflammasome
PMCID: Pubmed No.:31354519
Autoinducer-2 of Fusobacterium nucleatum promotes macrophage M1 polarization via TNFSF9/IL-1β signaling
PMCID: Pubmed No.:31272064
Vitamin D alleviates airway remodeling in asthma by down-regulating the activity of Wnt/β-catenin signaling pathway
PMCID: Pubmed No.:30616171
Epidermal growth factor‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1) suppressed the growth of hepatocellular carcinoma cells by promoting Semaphorin 3B(SEMA3B)
PMCID: Pubmed No.:30972979
Effect of pre-slaughter shackling and wing flapping on plasma parameters, postmortem metabolism, AMPK, and meat quality of broilers
PMCID: Pubmed No.:29462466
Roles of chicken growth hormone receptor antisense transcript in chicken muscle development and myoblast differentiation
PMCID: Pubmed No.:31376348
6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction
PMCID: Pubmed No.:30408433
THAP7 promotes cell proliferation by regulating the G1/S phase transition via epigenetically silencing p21 in lung adenocarcinoma
PMCID: Pubmed No.:31372002
Resveratrol Reverses Cigarette Smoke-Induced Urocystic Epithelial–Mesenchymal Transition via Suppression of STAT3 Phosphorylation in SV-HUC-1-Immortalized Human Urothelial Cells
PMCID: Pubmed No.:32063715
CD4+ CD25+ regulatory T cells promote hepatocellular carcinoma invasion via TGF-β1-induced epithelial–mesenchymal transition
PMCID: Pubmed No.:30643426
SOX5 promotes cell invasion and metastasis via activation of Twist-mediated epithelial–mesenchymal transition in gastric cancer
PMCID: Pubmed No.:31040690
DEP Domain-Containing Protein 1B (DEPDC1B) Promotes Migration and Invasion in Pancreatic Cancer Through the Rac1/PAK1-LIMK1-Cofilin1 Signaling Pathway
PMCID: Pubmed No.:32110046
PFND1 Predicts Poor Prognosis of Gastric Cancer and Promotes Cell Metastasis by Activating the Wnt/β-Catenin Pathway
PMCID: Pubmed No.:32368077
p70S6K Promotes Acquired Resistance of Erlotinib Through Induction of Epithelial-Mesenchymal Transition in Non-Small Cell Lung Carcinoma
PMCID: Pubmed No.:32606745
CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial– mesenchymal transition
PMCID: Pubmed No.:30288051
CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial– mesenchymal transition
PMCID: Pubmed No.:30288051
Polygalaxanthone III downregulates inflammation in the lipopolysaccharide-stimulated RAW264.7 macrophages: A quantibody array analysis
PMCID: Pubmed No.:34384566
SPIO nanoparticle-labeled bone marrow mesenchymal stem cells inhibit pulmonary EndoMT induced by SiO2
PMCID: Pubmed No.:31291564
Induction of Macrophage M2b/c Polarization by Adipose Tissue-Derived Mesenchymal Stem Cells
PMCID: Pubmed No.:31321244
Angiotensin-(1-7) induced vascular relaxation in spontaneously hypertensive rats
PMCID: Pubmed No.:30880106
Lamprey PHB2 maintains mitochondrial stability by tanslocation to the mitochondria under oxidative stress
PMCID: Pubmed No.:32592929
Dynein- and kinesin- mediated intracellular transport on microtubules facilitates RABV infection
PMCID: Pubmed No.:34555731
ZC3H4 mediates silica-induced EndoMT via ER stress and autophagy
PMCID: Pubmed No.:33545378
Inhibition of glioma growth by a GOLPH3 siRNA-loaded cationic liposomes
PMCID: Pubmed No.:30105446
HSC-specific knockdown of GGPPS alleviated CCl4-induced chronic liver fibrosis through mediating RhoA/Rock pathway
PMCID: Pubmed No.:31105844
Aesculin protects against DSS-Induced colitis though activating PPARγ and inhibiting NF-кB pathway
PMCID: Pubmed No.:31202807
Auranofin lethality to prostate cancer includes inhibition of proteasomal deubiquitinases and disrupted androgen receptor signaling
PMCID: Pubmed No.:30639309
Metformin and MiR-365 synergistically promote the apoptosis of gastric cancer cells via MiR-365-PTEN-AMPK axis
PMCID: Pubmed No.:35007850
Integrated Network Pharmacology Analysis and Pharmacological Evaluation to Explore the Active Components and Mechanism of Abelmoschus manihot (L.) Medik. on Renal Fibrosis
PMCID: Pubmed No.:33061308
Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway
PMCID: Pubmed No.:31849446
N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury
PMCID: Pubmed No.:30584276
Chloroquine and 3-Methyladenine Attenuates Periodontal Inflammation and Bone Loss in Experimental Periodontitis
PMCID: Pubmed No.:31720989
Cyclin-Dependent Kinase 9 Inhibition Suppresses Necroptosis and Pyroptosis in the Progress of Endotoxemia
PMCID: Pubmed No.:32556803
Segmented scan modes and polarity-based LC-MS for pharmacokinetic interaction study between Fufang Danshen Dripping Pill and Clopidogrel Bisulfate Tablet
PMCID: Pubmed No.:31202879
Neuroprotective effects of ZL006 in Aβ1–42-treated neuronal cells
PMCID: Pubmed No.:32594052
IRS-1 targets TAZ to inhibit adipogenesis of rat bone marrow mesenchymal stem cells through PI3K-Akt and MEK-ERK pathways
PMCID: Pubmed No.:30716312
TEKT4 Promotes Papillary Thyroid Cancer Cell Proliferation, Colony Formation, and Metastasis through Activating PI3K/Akt Pathway
PMCID: Pubmed No.:30251060
ALDH1A3 serves as a predictor for castration resistance in prostate cancer patients
PMCID: Pubmed No.:32375698
Behavioral Abnormality along with NMDAR-related CREB Suppression in Rat Hippocampus after Shortwave Exposure
PMCID: Pubmed No.:30987693
AKAP12 Endogenous Transcripts Suppress The Proliferation, Migration And Invasion Of Colorectal Cancer Cells By Directly Targeting oncomiR-183-5p
PMCID: Pubmed No.:31632079
TRIM37 promotes cell invasion and metastasis by regulating SIP1-mediated epithelial–mesenchymal transition in gastric cancer
PMCID: Pubmed No.:30573971
Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression
PMCID: Pubmed No.:30613152
Transcobalamin I: a novel prognostic biomarker of neoadjuvant chemotherapy in locally advanced hypopharyngeal squamous cell cancers
PMCID: Pubmed No.:30100732
miR‑498 inhibits the growth and metastasis of liver cancer by targeting ZEB2
PMCID: Pubmed No.:30592286
β‑carotene reverses tobacco smoke‑induced gastric EMT via Notch pathway in vivo
PMCID: Pubmed No.:29393400
Ketone Metabolite β-Hydroxybutyrate Ameliorates Inflammation After Spinal Cord Injury by Inhibiting the NLRP3 Inflammasome
PMCID: Pubmed No.:33108630
PKC Mediates LPS-Induced IL-1β Expression and Participates in the Pro-inflammatory Effect of A 2A R Under High Glutamate Concentrations in Mouse Microglia
PMCID: Pubmed No.:31650360
Cytological and spectroscopic characteristics of c‐KIT N822K mutation in core binding factor acute myeloid leukemia cells
PMCID: Pubmed No.:32390317
Repurposing bortezomib for choroidal neovascularization treatment via antagonizing VEGF-A and PDGF-D mediated signaling
PMCID: Pubmed No.:33476605
Modulation of gut microbiota contributes to effects of intensive insulin therapy on intestinal morphological alteration in high-fat-diet-treated mice
PMCID: Pubmed No.:31749050
RNPS1 inhibition aggravates ischemic brain injury and promotes neuronal death
PMCID: Pubmed No.:31831174
MiR-139-5p suppresses osteosarcoma cell growth and invasion through regulating DNMT1
PMCID: Pubmed No.:29673587
Metformin promotes the osseointegration of titanium implants under osteoporotic conditions by regulating BMSCs autophagy, and osteogenic differentiation
PMCID: Pubmed No.:32800340
Ran participates in deltamethrin stress through regulating the nuclear import of Nrf2
PMCID: Pubmed No.:33069802
Overinhibition mediated by parvalbumin interneurons might contribute to depression-like behavior and working memory impairment induced by lipopolysaccharide challenge
PMCID: Pubmed No.:31987933
Inhibition of Dishevelled‑2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β‑catenin signaling
PMCID: Pubmed No.:34589148
Study on Association of Pentraxin 3 and Diabetic Nephropathy in a Rat Model
PMCID: Pubmed No.:29725602
Salidroside inhibits endothelial‑mesenchymal transition via the KLF4/eNOS signaling pathway
PMCID: Pubmed No.:34368873
Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats
PMCID: Pubmed No.:33786621
LINC00461/miR-4478/E2F1 feedback loop promotes non-small cell lung cancer cell proliferation and migration
PMCID: Pubmed No.:31934717
BMP9 exhibits dual and coupled roles in inducing osteogenic and angiogenic differentiation of mesenchymal stem cells
PMCID: Pubmed No.:32478395
Leptin-induced inflammation by activating IL-6 expression contributes to the fibrosis and hypertrophy of ligamentum flavum in lumbar spinal canal stenosis
PMCID: Pubmed No.:29436483
TGF-β1 induces epithelial-to-mesenchymal transition via inhibiting mitochondrial functions in A549 cells
PMCID: Pubmed No.:30203703
Xingnaojing ameliorates synaptic plasticity and memory deficits in an Aβ1–42 induced mouse model of Alzheimer's disease
PMCID: Pubmed No.:32482409
Chinese medicine Di-Huang-Yi-Zhi protects PC12 cells from H 2 O 2 -induced apoptosis by regulating ROS-ASK1-JNK/p38 MAPK signaling
PMCID: Pubmed No.:32059723
Oridonin inhibits metastasis of human ovarian cancer cells by suppressing the mTOR pathway
PMCID: Pubmed No.:31360196
Overexpression of CTRP9 attenuates the development of atherosclerosis in apolipoprotein E-deficient mice
PMCID: Pubmed No.:30426302
Sodium butyrate improves antioxidant stability in sub-acute ruminal acidosis in dairy goats
PMCID: Pubmed No.:30200953
RhoA protects the podocytes against high glucose-induced apoptosis through YAP and plays critical role in diabetic nephropathy
PMCID: Pubmed No.:30220545
Betaine improves the growth performance and muscle growth of partridge shank broiler chickens via altering myogenic gene expression and insulin-like growth factor-1 signaling pathway
PMCID: Pubmed No.:30085311
Golgi Membrane Protein 1 (GOLM1) Promotes Growth and Metastasis of Breast Cancer Cells via Regulating Matrix Metalloproteinase-13 (MMP13)
PMCID: Pubmed No.:30695018
Andrographolide Inhibition of Th17-Regulated Cytokines and JAK1/STAT3 Signaling in OVA-Stimulated Asthma in Mice
PMCID: Pubmed No.:34194525
Identification of Goose PKR Gene: Structure, Expression Profiling, and Antiviral Activity Against Newcastle Disease Virus
PMCID: Pubmed No.:30052119
Higenamine Improves Cardiac and Renal Fibrosis in Rats With Cardiorenal Syndrome via ASK1 Signaling Pathway
PMCID: Pubmed No.:32168151
Entry of Challenge Virus Standard (CVS) -11 into N2a cells via a clathrin-mediated, cholesterol-, dynamin-, pH-dependent endocytic pathway
PMCID: Pubmed No.:31196105
HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma
PMCID: Pubmed No.:33559901
Knockdown of Kinesin Family 15 Inhibits Osteosarcoma through Suppressing Cell Proliferation and Promoting Cell Apoptosis
PMCID: Pubmed No.:32074608
MiR-218-5p targets LHFPL3 to regulate proliferation, migration, and epithelial–mesenchymal transitions of human glioma cells
PMCID: Pubmed No.:30314994
Effects of CD100 promote wound healing in diabetic mice
PMCID: Pubmed No.:29637382
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling
PMCID: Pubmed No.:30972697
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity
PMCID: Pubmed No.:32669967
LncRNA SNHG1 promotes EMT process in gastric cancer cells through regulation of the miR-15b/DCLK1/Notch1 axis.
PMCID: Pubmed No.:32423385
A novel rat model of seminal vesiculitis
PMCID: Pubmed No.:30460934
Perfluorooctane sulfonate induces heart toxicity involving cardiac apoptosis and inflammation in rats
PMCID: Pubmed No.:34815766
Hydrogen gas alleviates acute alcohol‑induced liver injury by inhibiting JNK activation
PMCID: Pubmed No.:33767761
Cocaine- and amphetamine-regulated transcript protects synaptic structures in neurons after ischemic cerebral injury
PMCID: Pubmed No.:32005500
Mitochondrial ATP-Sensitive K+ Channel Opening Increased the Airway Smooth Muscle Cell Proliferation by Activating the PI3K/AKT Signaling Pathway in a Rat Model of Asthma
PMCID: Pubmed No.:34336047
Tetrandrine alleviates cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via Sirt-1
PMCID: Pubmed No.:32419986
microRNA-29b prevents renal fibrosis by attenuating renal tubular epithelial cell–mesenchymal transition through targeting the PI3K/AKT pathway
PMCID: Pubmed No.:33742315
Effect of Heat Treatment on the Anticancer Activity of Houttuynia cordata Thunb Aerial Stem Extract in Human Gastric Cancer SGC-7901 Cells
PMCID: Pubmed No.:32180441
Halofuginone inhibits tumorigenic progression of 5‑FU‑resistant human colorectal cancer HCT‑15/FU cells by targeting miR‑132‑3p in vitro
PMCID: Pubmed No.:33154782
Knockdown of neuron‑specific enolase suppresses the proliferation and migration of NCI‑H209 cells
PMCID: Pubmed No.:31611991
Antitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF‑κB/caspase‑3 signaling pathways
PMCID: Pubmed No.:30333875
Konjac glucomannan reverses multi‑drug resistance of HepG2/5‑FU cells by suppressing AKT signaling and increasing p53 expression
PMCID: Pubmed No.:32782527
Fluvastatin-Pretreated Donor Cells Attenuated Murine aGVHD by Balancing Effector T Cell Distribution and Function under the Regulation of KLF2
PMCID: Pubmed No.:33415155
Decreased Endometrial IL-10 Impairs Endometrial Receptivity by Downregulating HOXA10 Expression in Women with Adenomyosis
PMCID: Pubmed No.:30687738
Yunnan Baiyao Conditioned Medium Promotes the Odonto/Osteogenic Capacity of Stem Cells from Apical Papilla via Nuclear Factor Kappa B Signaling Pathway
PMCID: Pubmed No.:31179335
Effects of long-term rapamycin treatment on glial scar formation after cryogenic traumatic brain injury in mice
PMCID: Pubmed No.:29727731
Evodiamine inhibits vasculogenic mimicry in HCT116 cells by suppressing hypoxia-inducible factor 1-alpha-mediated angiogenesis
PMCID: Pubmed No.:33394687
SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis
PMCID: Pubmed No.:30349378
CNOT7 depletion reverses natural killer cell resistance by modulating the tumor immune microenvironment of hepatocellular carcinoma
PMCID: Pubmed No.:32160402
Leptin-regulated autophagy plays a role in long-term neurobehavioral injury after neonatal seizures and the regulation of zinc/cPLA2 and CaMK II signaling in cerebral cortex
PMCID: Pubmed No.:30092488
-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells
PMCID: Pubmed No.:30363706
-Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells
PMCID: Pubmed No.:30363706
A Novel Cerebroprotein Hydrolysate, CH1, Ameliorates Chronic Focal Cerebral Ischemia Injury by Promoting White Matter Integrity via the Shh/Ptch-1/Gli-1 Signaling Pathway
PMCID: Pubmed No.:33380798
Sustained activation of C3aR in a human podocyte line impairs the morphological maturation of the cells
PMCID: Pubmed No.:33174024
Synergistic anticancer effects of bufalin and sorafenib by regulating apoptosis associated proteins
PMCID: Pubmed No.:29693132
Mild hypothermia reduces endoplasmic reticulum stress‐induced apoptosis and improves neuronal functions after severe traumatic brain injury
PMCID: Pubmed No.:30834702
The GLP-1/GIP dual-receptor agonist DA5-CH inhibits the NF-κB inflammatory pathway in the MPTP mouse model of Parkinson's disease more effectively than the GLP-1 single-receptor agonist NLY01
PMCID: Pubmed No.:34125470
Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats
PMCID: Pubmed No.:31615408
Sorafenib blocks the activation of the HIF-2α/VEGFA/EphA2 pathway, and inhibits the rapid growth of residual liver cancer following high-intensity focused ultrasound therapy in vivo
PMCID: Pubmed No.:33640712
Salvianolic acid A inhibits tumor-associated angiogenesis by blocking GRP78 secretion
PMCID: Pubmed No.:30560355
LncRNA linc00460 sponges miR-1224-5p to promote esophageal cancer metastatic potential and epithelial-mesenchymal transition
PMCID: Pubmed No.:32534700
Angiotensin-(1-9) ameliorates pulmonary arterial hypertension via angiotensin type II receptor
PMCID: Pubmed No.:29962859
Glucose-Related Protein 78 Expression and Its Effects on Cisplatin-Resistance in Cervical Cancer
PMCID: Pubmed No.:29650944
Effects of bradykinin on the survival of multiterritory perforator flaps in rats
PMCID: Pubmed No.:30813916
IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells
PMCID: Pubmed No.:30530508
Nur77 promotes embryo adhesion by transcriptionally regulating HOXA10 expression
PMCID: Pubmed No.:31574241
Aqueous extract of Chrysanthemum morifolium Ramat. inhibits RANKL-induced osteoclast differentiation by suppressing the c-fos/NFATc1 pathway
PMCID: Pubmed No.:33387850
In Vitro Expression of Cytokeratin 19 in Adipose-Derived Stem Cells Is Induced by Epidermal Growth Factor
PMCID: Pubmed No.:29925829
RANK Deficiency Ameliorates Podocyte Injury by Suppressing Calcium/Calcineurin/ NFATc1 Signaling
PMCID: Pubmed No.:30036881
Liriodenine enhances radiosensitivity in esophageal cancer ECA‑109 cells by inducing apoptosis and G2/M arrest
PMCID: Pubmed No.:30250568
L-Theanine Down-Regulates the JAK/STAT3 Pathway to Attenuate the Proliferation and Migration of Vascular Smooth Muscle Cells Induced by Angiotensin II
PMCID: Pubmed No.:30381668
EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer
PMCID: Pubmed No.:29620175
Inhibition of autophagy after perforator flap surgery increases flap survival and angiogenesis
PMCID: Pubmed No.:30278973
Involvement of hypoxia-inducible factor-1 alpha in the upregulation of P-glycoprotein in refractory epilepsy
PMCID: Pubmed No.:31634239
Malonic acid suppresses lipopolysaccharide-induced BV2 microglia cell activation by inhibiting the p38 MAPK/NF-κB pathway
PMCID: Pubmed No.:34234892
Neferine Exerts Antioxidant and Anti-Inflammatory Effects on Carbon Tetrachloride-Induced Liver Fibrosis by Inhibiting the MAPK and NF-κB/IκBα Pathways
PMCID: Pubmed No.:33680053
Xiao-Yao-San Formula Improves Cognitive Ability by Protecting the Hippocampal Neurons in Ovariectomized Rats
PMCID: Pubmed No.:32655660
Si-Wu-Tang Alleviates Nonalcoholic Fatty Liver Disease via Blocking TLR4-JNK and Caspase-8-GSDMD Signaling Pathways
PMCID: Pubmed No.:32849904
MicroRNA‑9 inhibits gastric cancer cell proliferation and migration by targeting neuropilin‑1
PMCID: Pubmed No.:31572503
Blocking of BDNF-TrkB signaling inhibits the promotion effect of neurological function recovery after treadmill training in rats with spinal cord injury
PMCID: Pubmed No.:30002472
Ginkgolide B improves multiterritory perforator flap survival by inhibiting endoplasmic reticulum stress and oxidative stress
PMCID: Pubmed No.:31870195
Effects of dietary supplementation with betaine on muscle growth, muscle amino acid contents and meat quality in Cherry Valley ducks
PMCID: Pubmed No.:31140661
Silencing of Proteasome 26S Subunit ATPase 2 Regulates Colorectal Cancer Cell Proliferation, Apoptosis, and Migration
PMCID: Pubmed No.:31715603
Advanced oxidation protein products inhibit the autophagy of renal tubular epithelial cells
PMCID: Pubmed No.:29556265
Long Noncoding RNA EGFR-AS1 Promotes Cell Proliferation by Increasing EGFR mRNA Stability in Gastric Cancer
PMCID: Pubmed No.:30138934
Inhibition of Proteasomal Deubiquitinase by Silver Complex Induces Apoptosis in Non-Small Cell Lung Cancer Cells
PMCID: Pubmed No.:30165348
Deubiquitinase Inhibitor Auranofin Attenuated Cardiac Hypertrophy by Blocking NF-κB Activation
PMCID: Pubmed No.:29554646
Autophagy Facilitates Metadherin-Induced Chemotherapy Resistance Through the AMPK/ATG5 Pathway in Gastric Cancer
PMCID: Pubmed No.:29635244
Enhanced nuclear localization of YAP1-2 contributes to EGF-induced EMT in NSCLC
PMCID: Pubmed No.:35014181
ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop
PMCID: Pubmed No.:34979141
Proline-rich transmembrane protein 2 specifically binds to GluA1 but has no effect on AMPA receptor-mediated synaptic transmission
PMCID: Pubmed No.:34997978
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2
PMCID: Pubmed No.:35326233
The cardiotoxicity of asthmatic rats after traffic-related PM2.5 and water-soluble components exposure mediated by endoplasmic reticulum stress and autophagy
PMCID: Pubmed No.:35235115
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways
PMCID: Pubmed No.:35307375
Prohibitin Protects Pulmonary Microvascular Endothelial Cells Against Cigarette Smoke Extract-Induced Cell Apoptosis and Inflammation
PMCID: Pubmed No.:35378837
Brown adipose tissue involution associated with progressive restriction in progenitor competence
PMCID: Pubmed No.:35417710
Upregulation of COPB2 Promotes Prostate Cancer Proliferation and Invasion Through the MAPK/TGF-β Signaling Pathway
PMCID: Pubmed No.:35600351
Phytoestrogen arctigenin preserves the mucus barrier in inflammatory bowel diseases by inhibiting goblet cell apoptosis via the ERβ/TRIM21/PHB1 pathway
PMCID: Pubmed No.:35599350
Contribution of Amygdala Histone Acetylation in Early Life Stress-Induced Visceral Hypersensitivity and Emotional Comorbidity
PMCID: Pubmed No.:35600618
Knockout of cyclin B1 in granulosa cells causes female subfertility
PMCID: Pubmed No.:35536551
Chemical characteristics of Rhodiola Crenulata and its mechanism in acute mountain sickness using UHPLC-Q-TOF-MS/MS combined with network pharmacology analysis
PMCID: Pubmed No.:35526732
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma
PMCID: Pubmed No.:35856434
YAP9/A20 complex suppresses proinflammatory responses and provides novel anti-inflammatory therapeutic potentials.
PMCID: Pubmed No.:36045678
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10
PMCID: Pubmed No.:35962397
Rapamycin inhibits hepatitis B virus covalently closed circular DNA transcription by enhancing the ubiquitination of HBx
PMCID: Pubmed No.:36033851
Around-the-Clock Noise Induces AD-like Neuropathology by Disrupting Autophagy Flux Homeostasis
PMCID: Pubmed No.:36078149
Reduced N6-methyladenosine mediated by METTL3 acetylation promotes MTF1 expression and hepatocellular carcinoma cell growth
PMCID: Pubmed No.:36149370
Tabersonine alleviates obesity-induced cardiomyopathy by binding to Transforming growth factor activated kinase 1 (TAK1) and inhibiting TAK1-mediated inflammation
PMCID: Pubmed No.:36420902
A splicing-dependent ER retention signal regulates surface expression of the mechanosensitive TMEM63B cation channel
PMCID: Pubmed No.:36496074
Effects of Cinobufagin on the Proliferation, Migration, and Invasion of H1299 Lung Cancer Cells
PMCID: Pubmed No.:36522286
Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects
PMCID: Pubmed No.:36690096
Adipose-Derived Mesenchymal Stem Cells Inhibit JNK-Mediated Mitochondrial Retrograde Pathway to Alleviate Acetaminophen-Induced Liver Injury
PMCID: Pubmed No.:36671020
The effect of regulating MCU expression on experimental ischemic brain injury
PMCID: Pubmed No.:36702427
Huangkui capsule alleviates adriamycin-induced proteinuria via protecting against podocyte damage and inhibiting JAK/STAT signaling
PMCID: Pubmed No.:36608778
Bicyclol Alleviates Streptozotocin-induced Diabetic Cardiomyopathy By Inhibiting Chronic Inflammation And Oxidative Stress
PMCID: Pubmed No.:36662448
IBV QX affects the antigen presentation function of BMDCs through non-structural protein16
PMCID: Pubmed No.:36972672
USP25 inhibits renal fibrosis by regulating TGFβ-SMAD signaling pathway in Ang II-induced hypertensive mice
PMCID: Pubmed No.:37059312
AURKB Enhances Chromosomal Remodeling of Telomeric Genes and Accelerates Tumorigenesis of Uveal Melanoma
PMCID: Pubmed No.:37079315
CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation
PMCID: Pubmed No.:37210387
1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway
PMCID: Pubmed No.:37380045
SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression
PMCID: Pubmed No.:37525212
USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2
PMCID: Pubmed No.:37587766
OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6
PMCID: Pubmed No.:37608493
USP25 ameliorates diabetic nephropathy by inhibiting TRAF6-mediated inflammatory responses
PMCID: Pubmed No.:37657242
PCSK9 causes inflammation and cGAS/STING pathway activation in diabetic nephropathy
PMCID: Pubmed No.:37561547
Hydrogen Sulfide Prevents LPS-Induced Depression-like Behavior through the Suppression of NLRP3 Inflammasome and Pyroptosis and the Improvement of Mitochondrial Function in the Hippocampus of Mice
PMCID: Pubmed No.:37626978
ETV5 facilitates tumor progression in head-neck squamous cell carcinoma
PMCID: Pubmed No.:37649213
Cold-inducible PPA1 is critical for the adipocyte browning in mice
PMCID: Pubmed No.:37549601
Water extract of frankincense and myrrh inhibits liver cancer progression and epithelial‑mesenchymal transition through Wnt/β‑catenin signaling
PMCID: Pubmed No.:37719039
ZC3H4 governs epithelial cell migration through ROCK/p-PYK2/p-MLC2 pathway in silica-induced pulmonary fibrosis
PMCID: Pubmed No.:37866415
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.