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GAPDH (1A6) monoclonal antibody MB001
  • Western blot (WB) analysis of GAPDH (1A6) mAb at 1:20000/1:10000 dilution Lane1:L02 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:MG63 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Rat(40ug) Lane7:The Brain tissue lysate of Mouse(40ug)
  • Immunohistochemistry analyzes of GAPDH (1A6) antibody in paraffin-embedded human liver tissue
  • Immunohistochemistry analyzes of GAPDH (1A6) antibody in paraffin-embedded human liver tissue
Product NameGAPDH (1A6) monoclonal antibody
Catalog No.MB001
Swiss-ProtN/A
Host Mouse
ReactivityHuman,Mouse,Rat
ApplicationsELISA WB IHC IF
Application_allELISA: 1:50000~1:100000 WB: 1:10000 IHC:1:500~1:1000 IF:1:500~1:1000
BiowMW~ 36 kDa
Alternative NameGlyceraldehyde-3-phosphate dehydrogenase; GAPDH; GAPD
Purification&PurityThe antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ConjugateUnconjugated
ModificationUnmodification
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100ul $258
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Product Name :
GAPDH (1A6) monoclonal antibody
Background :
Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels.
Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
GAPDH (1A6) mAb detects endogenous levels of GAPDH protein.
Immunogen :
Recombinant full length Human GAPDH.
Conjugate :
Unconjugated
Modification :
Unmodification
  • Western blot (WB) analysis of GAPDH (1A6) mAb at 1:20000/1:10000 dilution Lane1:L02 whole cell lysate(40ug) Lane2:A549 whole cell lysate(40ug) Lane3:MG63 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug) Lane6:The Brain tissue lysate of Rat(40ug) Lane7:The Brain tissue lysate of Mouse(40ug)
  • Immunohistochemistry analyzes of GAPDH (1A6) antibody in paraffin-embedded human liver tissue
  • Immunohistochemistry analyzes of GAPDH (1A6) antibody in paraffin-embedded human liver tissue
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Epithelial Cells Infected with Enterovirus 71 PMCID:    Pubmed No.:27007979 SPARC inhibits breast cancer bone metastasis and may be a clinical therapeutic target PMCID:    Pubmed No.:29113221 Protective role of Klotho on cardiomyocytes upon hypoxia/reoxygenation via downregulation of Akt and FOXO1 phosphorylation Retraction in /10.3892/mmr.2015.3177 PMCID:    Pubmed No.:25377663 Sanggenon C protects against pressure overload‑induced cardiac hypertrophy via the calcineurin/NFAT2 pathway PMCID:    Pubmed No.:28849031 MicroRNA‑497 inhibits tumor growth through targeting insulin receptor substrate 1 in colorectal cancer PMCID:    Pubmed No.:29163678 Low‑level mechanical vibration enhances osteoblastogenesis via a canonical Wnt signaling‑associated mechanism PMCID:    Pubmed No.:28534995 Chrysin inhibits human airway smooth muscle cells proliferation through the extracellular signal‑regulated kinase 1/2 signaling pathway PMCID:    Pubmed No.:26502995 Hesperetin protects against inflammatory response and cardiac fibrosis in postmyocardial infarction mice by inhibiting nuclear factor κB signaling pathway PMCID:    Pubmed No.:28962151 Naringenin inhibits transforming growth factor‑β1‑induced cardiac fibroblast proliferation and collagen synthesis via G0/G1 arrest PMCID:    Pubmed No.:29104653 Naringenin attenuates pressure overload-induced cardiac hypertrophy PMCID:    Pubmed No.:26668617 Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway PMCID:    Pubmed No.:26722438 Cinnamaldehyde attenuates pressure overload-induced cardiac hypertrophy PMCID:    Pubmed No.:26823750 Myocardial apoptosis and injury of donor hearts kept in completely beating status with normothermic blood perfusion for transplants PMCID:    Pubmed No.:26131163 Danshen improves damaged cardiac angiogenesis and cardiac function induced by myocardial infarction by modulating HIF1α/VEGFA signaling pathway PMCID:    Pubmed No.:26770433 Puerarin accelerate scardiac angiogenesis and improves cardiac function of myocardial infarction by upregulating VEGFA, Ang-1 and Ang-2 in rats PMCID:    Pubmed No.:26885006 Role of microRNA-134 in the neuroprotective effects of propofol against oxygen-glucose deprivation and related mechanisms PMCID:    Pubmed No.:26884981 TES inhibits colorectal cancer progression through activation of p38 PMCID:    Pubmed No.:27323777 Anti-angiogenic efficacy of 5′-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs PMCID:    Pubmed No.:26336994 The N-Degron Pathway Mediates ER-phagy PMCID:    Pubmed No.:31375263 The δ subunit of F1Fo-ATP synthase is required for pathogenicity of Candida albicans PMCID:    Pubmed No.:34654833 Exosomes with low miR-34c-3p expression promote invasion and migration of non-small cell lung cancer by upregulating integrin α2β1 PMCID:    Pubmed No.:32317629 Injectable AuNP-HA matrix with localized stiffness enhances the formation of gap junction in engrafted human induced pluripotent stem cell-derived cardiomyocytes and promotes cardiac repair PMCID:    Pubmed No.:34739980 A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells PMCID:    Pubmed No.:30911006 Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1 PMCID:    Pubmed No.:33484341 Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer PMCID:    Pubmed No.:32248842 The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression PMCID:    Pubmed No.:31126313 Sirtuin 6 is a negative regulator of FcεRI signaling and anaphylactic responses PMCID:    Pubmed No.:34051221 Sirtuin 6 in preosteoclasts suppresses age- and estrogen deficiency-related bone loss by stabilizing estrogen receptor α PMCID:    Pubmed No.:30787391 Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer PMCID:    Pubmed No.:29685157 Cyclin B2 can compensate for Cyclin B1 in oocyte meiosis I PMCID:    Pubmed No.:30097513 Depletion of glioma stem cells by synergistic inhibition of mTOR and c-Myc with a biological camouflaged cascade brain-targeting nanosystem PMCID:    Pubmed No.:33296794 Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK PMCID:    Pubmed No.:32283380 Sirt1-Overexpressing Mesenchymal Stem Cells Drive the Anti-tumor Effect through Their Pro-inflammatory Capacity PMCID:    Pubmed No.:32027844 CRISPR/Cas9-Mediated miR-29b Editing as a Treatment of Different Types of Muscle Atrophy in Mice PMCID:    Pubmed No.:32222157 A Novel mTORC1/2 Inhibitor (MTI-31) Inhibits Tumor Growth, Epithelial–Mesenchymal Transition, Metastases, and Improves Antitumor Immunity in Preclinical Models of Lung Cancer PMCID:    Pubmed No.:30796032 Controlling the Multiscale Network Structure of Fibers To Stimulate Wound Matrix Rebuilding by Fibroblast Differentiation PMCID:    Pubmed No.:31251577 Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis PMCID:    Pubmed No.:31541078 Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development PMCID:    Pubmed No.:33754063 Fusobacterium nucleatum Promotes Metastasis in Colorectal Cancer by Activating Autophagy Signaling via the Upregulation of CARD3 Expression PMCID:    Pubmed No.:31903123 SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride PMCID:    Pubmed No.:32308752 The anti-microbial peptide LL-37/CRAMP levels are associated with acute heart failure and can attenuate cardiac dysfunction in multiple preclinical models of heart failure PMCID:    Pubmed No.:32483446 Single-cell transcriptome profiling reveals intratumoural heterogeneity and malignant progression in retinoblastoma PMCID:    Pubmed No.:34815392 A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels PMCID:    Pubmed No.:33934099 LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway PMCID:    Pubmed No.:34108447 miR-4293 upregulates lncRNA WFDC21P by suppressing mRNA-decapping enzyme 2 to promote lung carcinoma proliferation PMCID:    Pubmed No.:34301920 DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program PMCID:    Pubmed No.:31226106 HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury PMCID:    Pubmed No.:34666797 Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction PMCID:    Pubmed No.:34837851 Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake PMCID:    Pubmed No.:31534545 HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice PMCID:    Pubmed No.:32086291 Decreased Level of Exosomal miR-5121 Released from Microglia Suppresses Neurite Outgrowth and Synapse Recovery of Neurons Following Traumatic Brain Injury PMCID:    Pubmed No.:33475953 Interferon-Inducible LINC02605 Promotes Antiviral Innate Responses by Strengthening IRF3 Nuclear Translocation. PMCID:    Pubmed No.:34804040 Glycochenodeoxycholate promotes hepatocellular carcinoma invasion and migration by AMPK/mTOR dependent autophagy activation PMCID:    Pubmed No.:30980867 Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy PMCID:    Pubmed No.:30972284 Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway PMCID:    Pubmed No.:31783879 Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b PMCID:    Pubmed No.:33614226 Fusobacterium nucleatum promotes M2 polarization of macrophages in the microenvironment of colorectal tumours via a TLR4-dependent mechanism PMCID:    Pubmed No.:30121899 SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury PMCID:    Pubmed No.:33854356 Biological and RNA regulatory function of MOV10 in mammalian germ cells PMCID:    Pubmed No.:31088452 PRRX1 deficiency induces mesenchymal‐epithelial transition through PITX2/miR‐200–dependent SLUG/CTNNB1 regulation in hepatocellular carcinoma PMCID:    Pubmed No.:33587761 Functional recovery of a novel knockin mouse model of dysferlinopathy by readthrough of nonsense mutation PMCID:    Pubmed No.:34141825 Curculigoside Ameliorates Bone Loss by Influencing Mesenchymal Stem Cell Fate in Aging Mice. PMCID:    Pubmed No.:34926455 Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells PMCID:    Pubmed No.:34222256 Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination PMCID:    Pubmed No.:29353883 Tspan5 promotes epithelial–mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling PMCID:    Pubmed No.:33955149 Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation‐related signalling pathways PMCID:    Pubmed No.:31454852 Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway PMCID:    Pubmed No.:33867836 Dietary Protein From Different Sources Exerted a Great Impact on Lipid Metabolism and Mitochondrial Oxidative Phosphorylation in Rat Liver PMCID:    Pubmed No.:34513904 PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism PMCID:    Pubmed No.:33250241 Cytotoxicity of hexabromocyclododecane, 1,2-dibromo-4-(1,2-dibromoethyl) cyclohexane and 1,2,5,6-tetrabromocyclooctane in human SH-SY5Y neuroblastoma cells PMCID:    Pubmed No.:32758930 MICAL2 Contributes to Gastric Cancer Cell Proliferation by Promoting YAP Dephosphorylation and Nuclear Translocation PMCID:    Pubmed No.:34650666 Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps PMCID:    Pubmed No.:33868571 Therapeutic evaluation of acupoint stimulation with needle-scapelon on rat model of degenerative cervical intervertebral discs PMCID:    Pubmed No.:30553194 Differential toxicities of triptolide to immortalized podocytes and the podocytes in vivo PMCID:    Pubmed No.:30551497 Post-transcription mediated Snail stabilization is involved in radiation exposure induced invasion and migration of hepatocarcinoma cells PMCID:    Pubmed No.:29684855 Photothermal and gene therapy combined with immunotherapy to gastric cancer by the gold nanoshell-based system PMCID:    Pubmed No.:31277667 Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents PMCID:    Pubmed No.:33933753 Deubiquitination and stabilization of estrogen receptor α by ubiquitin-specific protease 7 promotes breast tumorigenesis PMCID:    Pubmed No.:31518603 Long non-coding RNA MCM3AP-AS1 promotes growth and migration through modulating FOXK1 by sponging miR-138-5p in pancreatic cancer PMCID:    Pubmed No.:31830901 HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models PMCID:    Pubmed No.:29113455 ALKBH5 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating PTEN expression in an m6A-dependent manner PMCID:    Pubmed No.:34438274 Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse PMCID:    Pubmed No.:34695613 Circ-SHPRH suppresses cadmium-induced transformation of human bronchial epithelial cells by regulating QKI expression via miR-224–5p PMCID:    Pubmed No.:34082244 TRPV3 enhances skin keratinocyte proliferation through EGFR-dependent signaling pathways PMCID:    Pubmed No.:32535744 Hypoxia-Induced miR-137 Inhibition Increased Glioblastoma Multiforme Growth and Chemoresistance Through LRP6 PMCID:    Pubmed No.:33718112 Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer PMCID:    Pubmed No.:33968724 S-nitrosylation of c-Jun N-terminal kinase mediates pressure overload-induced cardiac dysfunction and fibrosis PMCID:    Pubmed No.:34011968 Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer PMCID:    Pubmed No.:30250021 Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy PMCID:    Pubmed No.:35509816 Riboflavin deficiency affects lipid metabolism partly by reducing apolipoprotein B100 synthesis in rats PMCID:    Pubmed No.:31176989 Ets-1 deficiency alleviates nonalcoholic steatohepatitis via weakening TGF-β1 signaling-mediated hepatocyte apoptosis PMCID:    Pubmed No.:31189885 Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement PMCID:    Pubmed No.:31522191 Regulatory roles of miR-22/Redd1-mediated mitochondrial ROS and cellular autophagy in ionizing radiation-induced BMSC injury PMCID:    Pubmed No.:30846680 A miR-125b/CSF1-CX3CL1/tumor-associated macrophage recruitment axis controls testicular germ cell tumor growth PMCID:    Pubmed No.:30237497 miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma PMCID:    Pubmed No.:29531296 miR-129-5p targets Wnt5a to block PKC/ERK/NF-κB and JNK pathways in glioblastoma PMCID:    Pubmed No.:29531296 LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis PMCID:    Pubmed No.:31982491 Scutellarin, a modulator of mTOR, attenuates hepatic insulin resistance by regulating hepatocyte lipid metabolism via SREBP-1c suppression PMCID:    Pubmed No.:31828866 Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway PMCID:    Pubmed No.:34859513 Fusobacterium nucleatum Activates Endoplasmic Reticulum Stress to Promote Crohn’s Disease Development via the Upregulation of CARD3 Expression PMCID:    Pubmed No.:32153411 Combined Treatment With 2-(2-Benzofu-Ranyl)-2-Imidazoline and Recombinant Tissue Plasminogen Activator Protects Blood–Brain Barrier Integrity in a Rat Model of Embolic Middle Cerebral Artery Occlusion PMCID:    Pubmed No.:32595494 Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer PMCID:    Pubmed No.:34305593 A Single, Acute Astragaloside IV Therapy Protects Cardiomyocyte Through Attenuating Superoxide Anion-Mediated Accumulation of Autophagosomes in Myocardial Ischemia-Reperfusion Injury PMCID:    Pubmed No.:34349641 Targeting aerobic glycolysis by dichloroacetate improves Newcastle disease virus-mediated viro-immunotherapy in hepatocellular carcinoma PMCID:    Pubmed No.:31819179 NLRP3 Inflammasome-Dependent Increases in High Mobility Group Box 1 Involved in the Cognitive Dysfunction Caused by Tau-Overexpression PMCID:    Pubmed No.:34539383 Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children PMCID:    Pubmed No.:30659323 A new gold(I) complex-Au(PPh3)PT is a deubiquitinase inhibitor and inhibits tumor growth PMCID:    Pubmed No.:30527624 NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth PMCID:    Pubmed No.:34774047 RPL35A is a key promotor involved in the development and progression of gastric cancer PMCID:    Pubmed No.:34535139 Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo PMCID:    Pubmed No.:33931059 CircRNA NALCN acts as an miR-493-3p sponge to regulate PTEN expression and inhibit glioma progression PMCID:    Pubmed No.:34112159 HOXB7 acts as an oncogenic biomarker in head and neck squamous cell carcinoma PMCID:    Pubmed No.:34303375 Fludarabine as an Adjuvant Improves Newcastle Disease Virus-Mediated Antitumor Immunity in Hepatocellular Carcinoma PMCID:    Pubmed No.:31011625 Suppression of CCDC6 sensitizes tumor to oncolytic virus M1 PMCID:    Pubmed No.:33338804 Conditional deletion of Wntless in granulosa cells causes impaired corpora lutea formation and subfertility PMCID:    Pubmed No.:33291079 Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice PMCID:    Pubmed No.:31048563 Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer PMCID:    Pubmed No.:34623971 Near-infrared light-activatable siRNA delivery by microcapsules for combined tumour therapy PMCID:    Pubmed No.:29527926 Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway PMCID:    Pubmed No.:31234944 Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide PMCID:    Pubmed No.:31126320 MicroRNA-663 facilitates the growth, migration and invasion of ovarian cancer cell by inhibiting TUSC2 PMCID:    Pubmed No.:30944041 Glycochenodeoxycholate promotes the metastasis of gallbladder cancer cells by inducing epithelial to mesenchymal transition via activation of SOCS3/JAK2/STAT3 signaling pathway PMCID:    Pubmed No.:31347168 Dynamic recognition and repair of DNA complex damage PMCID:    Pubmed No.:30537094 Phosphoinositide 3‐kinase/protein kinase B inhibition restores regulatory T cell's function in pulmonary sarcoidosis PMCID:    Pubmed No.:30945303 Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy PMCID:    Pubmed No.:30585174 Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes PMCID:    Pubmed No.:31028245 Osterix regulates corticalization for longitudinal bone growth via integrin β3 expression PMCID:    Pubmed No.:30022046 Autophagy Activation is Associated with Neuroprotection in Diabetes-associated Cognitive Decline PMCID:    Pubmed No.:31788335 Involvement of the MiR-181b-5p/HMGB1 Pathway in Ang II-induced Phenotypic Transformation of Smooth Muscle Cells in Hypertension PMCID:    Pubmed No.:31011475 Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility PMCID:    Pubmed No.:31005715 A-kinase-interacting protein 1 facilitates growth and metastasis of gastric cancer cells via Slug-induced epithelial-mesenchymal transition PMCID:    Pubmed No.:31020809 Lactobacillus Protects Against S. Typhimurium–Induced Intestinal Inflammation by Determining the Fate of Epithelial Proliferation and Differentiation PMCID:    Pubmed No.:31953989 Fecal Microbiota Transplantation Protects the Intestinal Mucosal Barrier by Reconstructing the Gut Microbiota in a Murine Model of Sepsis PMCID:    Pubmed No.:34631604 LncRNA ENSMUST00000155383 is Involved in the Improvement of DPP-4 Inhibitor MK-626 on Vascular Endothelial Function by Modulating Cacna1c-Mediated Ca2+ Influx in Hypertensive Mice PMCID:    Pubmed No.:34368236 MicroRNA‐219 decreases hippocampal long‐term potentiation inhibition and hippocampal neuronal cell apoptosis in type 2 diabetes mellitus mice by suppressing the NMDAR signaling pathway PMCID:    Pubmed No.:29804319 Insulin-like growth factor binding protein-1 regulates HIF-1α degradation to inhibit apoptosis in hypoxic cardiomyocytes PMCID:    Pubmed No.:34531382 c-Myc Is a Major Determinant for Antitumor Activity of Aurora A Kinase Inhibitor MLN8237 in Thyroid Cancer PMCID:    Pubmed No.:30226440 The Krüppel-like factor 15-NFATc1 axis ameliorates podocyte injury: a novel rationale for using glucocorticoids in proteinuria diseases PMCID:    Pubmed No.:32478397 Mindin deficiency in macrophages protects against foam cell formation and atherosclerosis by targeting LXR-β PMCID:    Pubmed No.:29695588 Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Random Skin Flaps via ROS Elimination PMCID:    Pubmed No.:33898433 Dynamic resistance exercise increases skeletal muscle-derived FSTL1 inducing cardiac angiogenesis via DIP2A–Smad2/3 in rats following myocardial infarction PMCID:    Pubmed No.:33932887 Dysregulation of UDP-glucuronosyltransferases in CCl4 induced liver injury rats PMCID:    Pubmed No.:32380060 The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply PMCID:    Pubmed No.:31425655 Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR-miR-429 pathway PMCID:    Pubmed No.:33811696 Follicular fluid exosomes: Important modulator in proliferation and steroid synthesis of porcine granulosa cells PMCID:    Pubmed No.:33908671 ERα is a target for butein-induced growth suppression in breast cancer PMCID:    Pubmed No.:33294263 KLK11 suppresses cellular proliferation via inhibition of Wnt/β-catenin signaling pathway in esophageal squamous cell carcinoma PMCID:    Pubmed No.:31720087 Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis PMCID:    Pubmed No.:31718671 Circ_0088194 Promotes the Invasion and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the miR-766-3p/MMP2 Axis PMCID:    Pubmed No.:33692802 Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats PMCID:    Pubmed No.:31827689 Farrerol Directly Targets GSK-3β to Activate Nrf2-ARE Pathway and Protect EA.hy926 Cells against Oxidative Stress-Induced Injuries PMCID:    Pubmed No.:32082480 Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits PMCID:    Pubmed No.:32685087 Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression PMCID:    Pubmed No.:30150788 Isoflavones enhance pharmacokinetic exposure of active lovastatin acid via the upregulation of carboxylesterase in high-fat diet mice after oral administration of Xuezhikang capsules PMCID:    Pubmed No.:29921884 Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor PMCID:    Pubmed No.:33820450 Long noncoding RNA HOTAIR promotes renal cell carcinoma malignancy through alpha‐2, 8‐sialyltransferase 4 by sponging microRNA‐124 PMCID:    Pubmed No.:30105850 Silent information regulator 1 suppresses epithelial-to-mesenchymal transition in lung cancer cells via its regulation of mitochondria status PMCID:    Pubmed No.:34119539 Proteomes analysis reveals the involvement of autophagy in AD-like neuropathology induced by noise exposure and ApoE4 PMCID:    Pubmed No.:31228807 The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome PMCID:    Pubmed No.:31914678 Pharmacological activation of ERβ by arctigenin maintains the integrity of intestinal epithelial barrier in inflammatory bowel diseases PMCID:    Pubmed No.:31908053 The opposite functions of miR‐24 in the osteogenesis and adipogenesis of adipose‐derived mesenchymal stem cells are mediated by the HOXB7/β‐catenin complex PMCID:    Pubmed No.:32413244 The levels and significance of inflammasomes in the mouse retina following optic nerve crush PMCID:    Pubmed No.:30939414 Ulinastatin mediates suppression of regulatory T cells through TLR4/NF-κB signaling pathway in murine sepsis PMCID:    Pubmed No.:30261464 mTOR- and SGK-Mediated Connexin 43 Expression Participates in Lipopolysaccharide-Stimulated Macrophage Migration through the iNOS/Src/FAK Axis PMCID:    Pubmed No.:30341186 Serum- and glucocorticoid-inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1 PMCID:    Pubmed No.:33724645 l-Theanine attenuates neointimal hyperplasia via suppression of vascular smooth muscle cell phenotypic modulation PMCID:    Pubmed No.:32402912 ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway PMCID:    Pubmed No.:31281585 RRM2 is a potential prognostic biomarker with functional significance in glioma PMCID:    Pubmed No.:30745840 Knockdown of Kremen2 Inhibits Tumor Growth and Migration in Gastric Cancer PMCID:    Pubmed No.:33489867 Downregulation of miR-22 Contributes to Epithelial-Mesenchymal Transition in Osteosarcoma by Targeting Twist1 PMCID:    Pubmed No.:32391253 Discovery of coumarin-derived imino sulfonates as a novel class of potential cardioprotective agents PMCID:    Pubmed No.:31629165 Reduced miR-203 predicts metastasis and poor survival in esophageal carcinoma PMCID:    Pubmed No.:31844033 β-arrestin2 alleviates L-dopa–induced dyskinesia via lower D1R activity in Parkinson’s rats PMCID:    Pubmed No.:31891566 TYRO3 facilitates cell growth and metastasis via activation of the Wnt/β-catenin signaling pathway in human gastric cancer cells PMCID:    Pubmed No.:32018224 Protective effects of ginseng stem-leaf saponins on D-galactose-induced reproductive injury in male mice PMCID:    Pubmed No.:33714944 Resveratrol represses estrogen-induced mammary carcinogenesis through NRF2-UGT1A8-estrogen metabolic axis activation PMCID:    Pubmed No.:30009768 A Novel Anti-EGFR mAb Ame55 with Lower Toxicity and Better Efficacy than Cetuximab When Combined with Irinotecan PMCID:    Pubmed No.:30733972 Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice PMCID:    Pubmed No.:30946910 CircSPAG16 suppresses cadmium-induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt PMCID:    Pubmed No.:34081812 GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner PMCID:    Pubmed No.:31324725 A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway PMCID:    Pubmed No.:31396207 Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses PMCID:    Pubmed No.:30333836 A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis PMCID:    Pubmed No.:30425719 Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats PMCID:    Pubmed No.:32084453 Clinopodium chinense Attenuates Palmitic Acid-Induced Vascular Endothelial Inflammation and Insulin Resistance through TLR4-Mediated NF-κB and MAPK Pathways PMCID:    Pubmed No.:30776912 Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS‐G12D mutation and P53 knockout PMCID:    Pubmed No.:31410985 Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK‐ERK pathway PMCID:    Pubmed No.:30907511 Overexpression of ZEB2‐AS1 promotes epithelial‐to‐mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma PMCID:    Pubmed No.:30950191 MICAL1 facilitates breast cancer cell proliferation via ROS‐sensitive ERK/cyclin D pathway PMCID:    Pubmed No.:29524295 AR-mTOR-SRF Axis Regulates HMMR Expression in Human Prostate Cancer Cells PMCID:    Pubmed No.:34099592 Galectin-3 Interacts with C/EBPβ and Upregulates Hyaluronan-Mediated Motility Receptor Expression in Gastric Cancer PMCID:    Pubmed No.:31822520 NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity PMCID:    Pubmed No.:32805187 Mechanical Strain Regulates Myofibroblast Differentiation of Human Scleral Fibroblasts by YAP PMCID:    Pubmed No.:34658907 OCT4B-190 protects against ischemic stroke by modulating GSK-3β/HDAC6 PMCID:    Pubmed No.:30981804 Sodium-glucose co-transporter-2 (SGLT-2) inhibition reduces glucose uptake to induce breast cancer cell growth arrest through AMPK/mTOR pathway PMCID:    Pubmed No.:33068934 Rhodiola crenulata root extract ameliorates fructose-induced hepatic steatosis in rats: Association with activating autophagy PMCID:    Pubmed No.:32007914 Synergistic antitumour effects of triptolide plus 10-hydroxycamptothecin onbladder cancer PMCID:    Pubmed No.:31063955 PM2.5 promotes plaque vulnerability at different stages of atherosclerosis and the formation of foam cells via TLR4/MyD88/NFκB pathway PMCID:    Pubmed No.:30921699 MiR‐34a inhibits the proliferation, migration, and invasion of oral squamous cell carcinoma by directly targeting SATB2 PMCID:    Pubmed No.:31663131 Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice PMCID:    Pubmed No.:31988048 Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer’s Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2 PMCID:    Pubmed No.:32737764 SIRT1 induces the adipogenic differentiation of mouse embryonic stem cells by regulating RA-induced RAR expression via NCOR1 acetylation PMCID:    Pubmed No.:32217463 m6A methyltransferase METTL3 promotes retinoblastoma progression via PI3K/AKT/mTOR pathway PMCID:    Pubmed No.:33090698 Ubiquitin‐specific protease 2 regulates Ang Ⅱ–induced cardiac fibroblasts activation by up‐regulating cyclin D1 and stabilizing β‐catenin in vitro PMCID:    Pubmed No.:33314748 Inhibition of USP14 suppresses the formation of foam cell by promoting CD36 degradation PMCID:    Pubmed No.:31970862 Cistanche deserticola polysaccharide induces melanogenesis in melanocytes and reduces oxidative stress via activating NRF2/HO‐1 pathway PMCID:    Pubmed No.:32096914 Lentinan protects against pancreatic β‐cell failure in chronic ethanol consumption‐induced diabetic mice via enhancing β‐cell antioxidant capacity PMCID:    Pubmed No.:33837638 Alpha B‐crystallin promotes the invasion and metastasis of gastric cancer via NF‐κB‐induced epithelial‐mesenchymal transition PMCID:    Pubmed No.:29566309 Aging-Related Neural Disruption Might Predispose to Postoperative Cognitive Impairment Following Surgical Trauma PMCID:    Pubmed No.:33967044 The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway PMCID:    Pubmed No.:34425100 L-theanine inhibits foam cell formation via promoting the scavenger receptor A degradation PMCID:    Pubmed No.:34004205 Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression PMCID:    Pubmed No.:30775800 Long noncoding RNA LINC00961 inhibits cell proliferation and induces cell apoptosis in human non–small cell lung cancer PMCID:    Pubmed No.:30010215 Polyglutamine protein in tumor cells sensitizes tumor cells to natural killer cell cytolysis PMCID:    Pubmed No.:32580073 Downregulating Heparanase-Induced Vascular Normalization: A New Approach To Increase the Bioavailability of Chemotherapeutics in Solid Tumors PMCID:    Pubmed No.:30059227 Heat‐Shock protein A12A is a novel PCNA‐binding protein and promotes hepatocellular carcinoma growth PMCID:    Pubmed No.:32128976 Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements PMCID:    Pubmed No.:33446747 The expression of ATP-sensitive potassium channels in human umbilical arteries with severe pre-eclampsia PMCID:    Pubmed No.:33846486 Histone Deacetylase Inhibitor Alleviates the Neurodegenerative Phenotypes and Histone Dysregulation in Presenilins-Deficient Mice PMCID:    Pubmed No.:29867447 Immune response in piglets orally immunized with recombinant Bacillus subtilis expressing the capsid protein of porcine circovirus type 2 PMCID:    Pubmed No.:32046726 Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice PMCID:    Pubmed No.:30797958 Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor PMCID:    Pubmed No.:32018210 Rhein protects the myocardiac cells against hypoxia/reoxygention-induced injury by suppressing GSK3β activity PMCID:    Pubmed No.:30466606 Quercetin and kaempferol increase the intestinal absorption of isorhamnetin coexisting in Elaeagnus rhamnoides (L.) A. Nelson (Elaeagnaceae) extracts via regulating multidrug resistance-associated protein 2 PMCID:    Pubmed No.:30668394 Decreased immunoglobulin G in brain regions of elder female APOE4-TR mice accompany with Aβ accumulation PMCID:    Pubmed No.:30700991 Adrenomedullin Receptors in Rats with Obesity-Related Hypertension PMCID:    Pubmed No.:30276527 Downregulation of long noncoding RNA SNHG1 inhibits cell proliferation, metastasis, and invasion by suppressing the Notch‐1 signaling pathway in pancreatic cancer PMCID:    Pubmed No.:30520072 1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB PMCID:    Pubmed No.:30930772 YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways PMCID:    Pubmed No.:31031629 WNT7A Promotes EGF-Induced Migration of Oral Squamous Cell Carcinoma Cells by Activating β-Catenin/MMP9-Mediated Signaling PMCID:    Pubmed No.:32174831 Protective Effects of the Soluble Epoxide Hydrolase Inhibitor 1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea in a Rat Model of Permanent Middle Cerebral Artery Occlusion PMCID:    Pubmed No.:32184732 Tanshinone IIA Suppresses Proliferation and Inflammatory Cytokine Production of Synovial Fibroblasts from Rheumatoid Arthritis Patients Induced by TNF-α and Attenuates the Inflammatory Response in AIA Mice PMCID:    Pubmed No.:32499694 Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways PMCID:    Pubmed No.:32719603 Qianlie Xiaozheng Decoction Induces Autophagy in Human Prostate Cancer Cells via Inhibition of the Akt/mTOR Pathway PMCID:    Pubmed No.:29670523 Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses PMCID:    Pubmed No.:34755645 Inhibition of p22phox Suppresses Epithelial Ovarian Cancer Cell Proliferation and Tumorigenesis PMCID:    Pubmed No.:34093828 Curcumin enhances cisplatin sensitivity of human NSCLC cell lines through influencing Cu-Sp1-CTR1 regulatory loop PMCID:    Pubmed No.:30195880 Rosiglitazone metformin adduct inhibits hepatocellular carcinoma proliferation via activation of AMPK/p21 pathway PMCID:    Pubmed No.:30651718 GNG5 is a novel oncogene associated with cell migration, proliferation, and poor prognosis in glioma PMCID:    Pubmed No.:34098960 MYOD1 inhibits avian adipocyte differentiation via miRNA-206/ KLF4 axis PMCID:    Pubmed No.:33952351 Inhibitory Effects of Periplocin on Lymphoma Cells: A Network Pharmacology Approach and Experimental Validation PMCID:    Pubmed No.:33814899 Bilayered PLGA/PLGA-HAp Composite Scaffold for Osteochondral Tissue Engineering and Tissue Regeneration PMCID:    Pubmed No.:33465902 Proximity ligation assay mediated rolling circle amplification strategy for in situ amplified imaging of glycosylated PD-L1 PMCID:    Pubmed No.:34523014 Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats PMCID:    Pubmed No.:31391086 Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis PMCID:    Pubmed No.:32066482 CD8 + T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma PMCID:    Pubmed No.:29784005 Fusobacterium nucleatum Promotes the Development of Ulcerative Colitis by Inducing the Autophagic Cell Death of Intestinal Epithelial PMCID:    Pubmed No.:33330137 PM2.5 induces endothelial dysfunction via activating NLRP3 inflammasome PMCID:    Pubmed No.:34173703 Periodontitis-level butyrate-induced ferroptosis in periodontal ligament fibroblasts by activation of ferritinophagy PMCID:    Pubmed No.:33298848 Resveratrol inhibits bile acid‐induced gastric intestinal metaplasia via the PI3K/AKT/p‐FoxO4 signalling pathway PMCID:    Pubmed No.:33103284 dl‐3‐n‐butylphthalide preserves white matter integrity and alleviates cognitive impairment in mice with chronic cerebral hypoperfusion PMCID:    Pubmed No.:31334611 LncRNA PICART1 suppressed non-small cell lung cancer cells proliferation and invasion by targeting AKT1 signaling pathway PMCID:    Pubmed No.:30662662 A Ce(III) complex potently inhibits the activity and expression of tyrosine phosphatase SHP-2 PMCID:    Pubmed No.:31763642 Enrichment of cancer stem cells by agarose multi-well dishes and 3D spheroid culture PMCID:    Pubmed No.:30244317 Radix et Rhizoma Ginseng chemoprevents both initiation and promotion of cutaneous carcinoma by enhancing cell-mediated immunity and maintaining redox homeostasis PMCID:    Pubmed No.:32617038 Combination of chick embryo and nutrient mixture prevent D-galactose-induced cognitive deficits, immune impairment and oxidative stress in aging rat model PMCID:    Pubmed No.:30858562 Calretinin Participates in Regulating Steroidogenesis by PLC-Ca 2+ -PKC Pathway in Leydig Cells PMCID:    Pubmed No.:29743498 Chronic noise exposure exacerbates AD-like neuropathology in SAMP8 mice in relation to Wnt signaling in the PFC and hippocampus PMCID:    Pubmed No.:30279527 Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression PMCID:    Pubmed No.:31758083 The positive effect of chick embryo and nutrient mixture on bone marrow- derived mesenchymal stem cells from aging rats PMCID:    Pubmed No.:29728592 Enhancement of adenovirus infection and adenoviral vector-mediated gene delivery by bromodomain inhibitor JQ1 PMCID:    Pubmed No.:30068949 Striatal overexpression of β-arrestin2 counteracts L-dopa-induced dyskinesia in 6-hydroxydopamine lesioned Parkinson's disease rats PMCID:    Pubmed No.:31491493 Akt phosphorylation regulated by IKKε in response to low shear stress leads to endothelial inflammation via activating IRF3 PMCID:    Pubmed No.:33370582 Resveratrol alleviates oxidative stress caused by Streptococcus uberis infection via activating the Nrf2 signaling pathway PMCID:    Pubmed No.:33045565 UUO induces lung fibrosis with macrophage-myofibroblast transition in rats PMCID:    Pubmed No.:33540244 Lipoxin A4 reduces hyperoxia-induced lung injury in neonatal rats through PINK1 signaling pathway PMCID:    Pubmed No.:31152979 Interleukin 33 ameliorates disturbance of regulatory T cells in pulmonary sarcoidosis PMCID:    Pubmed No.:30195819 Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway PMCID:    Pubmed No.:32513156 Upregulation of Twist is involved in Gli1 induced migration and invasion of hepatocarcinoma cells PMCID:    Pubmed No.:29908118 Muscone Ameliorates Synaptic Dysfunction and Cognitive Deficits in APP/PS1 Mice PMCID:    Pubmed No.:32538849 Radiation Induces Apoptosis and Osteogenic Impairment through miR-22-Mediated Intracellular Oxidative Stress in Bone Marrow Mesenchymal Stem Cells PMCID:    Pubmed No.:30158985 Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy PMCID:    Pubmed No.:31926197 CTRP9 alleviates foam cells apoptosis by enhancing cholesterol efflux PMCID:    Pubmed No.:33352225 FOXE1 inhibits cell proliferation, migration and invasion of papillary thyroid cancer by regulating PDGFA PMCID:    Pubmed No.:31129275 Depletion of Microglia Attenuates Dendritic Spine Loss and Neuronal Apoptosis in the Acute Stage of Moderate Traumatic Brain Injury in Mice PMCID:    Pubmed No.:31397209 A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury PMCID:    Pubmed No.:31467487 Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase PMCID:    Pubmed No.:32508525 Effects of chronic stress on depressive-like behaviors and JMJD3 expression in the prefrontal cortex and hippocampus of C57BL/6 and ob/ob mice PMCID:    Pubmed No.:33340793 PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice PMCID:    Pubmed No.:29800919 Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma PMCID:    Pubmed No.:30021341 The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma PMCID:    Pubmed No.:29574282 MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer PMCID:    Pubmed No.:29567542 The Cellular Senescence-Inhibited Gene Is Essential for PPM1A Myristoylation To Modulate Transforming Growth Factor β Signaling PMCID:    Pubmed No.:30201805 Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice PMCID:    Pubmed No.:32581664 Scutellarin ameliorates high glucose-induced vascular endothelial cells injury by activating PINK1/Parkin-mediated mitophagy PMCID:    Pubmed No.:33485979 miR-19b-3p promotes human pancreatic cancer Capan-2 cells proliferation by targeting phosphatase and tension homolog PMCID:    Pubmed No.:31317006 Embryonic morphology observation and HOXC8 gene expression in crest cushions of Chinese Crested duck PMCID:    Pubmed No.:30529099 Exogenous hydrogen sulfide prevents lipopolysaccharide-induced inflammation by blocking the TLR4/NF-κB pathway in MAC-T cells PMCID:    Pubmed No.:31153885 Transcriptome analysis of the hippocampus in environmental noise-exposed SAMP8 mice reveals regulatory pathways associated with Alzheimer’s disease neuropathology PMCID:    Pubmed No.:31918655 Ursolic acid induces apoptosis and anoikis in colorectal carcinoma RKO cells PMCID:    Pubmed No.:33549076 Myrtenal and β-caryophyllene oxide screened from Liquidambaris Fructus suppress NLRP3 inflammasome components in rheumatoid arthritis PMCID:    Pubmed No.:34583676 Icariin Attenuates M1 Activation of Microglia and Aβ Plaque Accumulation in the Hippocampus and Prefrontal Cortex by Up-Regulating PPARγ in Restraint/Isolation-Stressed APP/PS1 Mice PMCID:    Pubmed No.:31001073 PGRN−/− TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration PMCID:    Pubmed No.:33181174 The in vitro effects of phospholipase D1-mTOR axis in liver fibrogenesis PMCID:    Pubmed No.:32240681 CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection PMCID:    Pubmed No.:33223223 Up-regulation of PTEN via LPS/AP-1/NF-κB pathway inhibits trophoblast invasion contributing to preeclampsia PMCID:    Pubmed No.:31896494 The possible molecular mechanisms of farnesol on the antifungal resistance of C. albicans biofilms: the regulation of CYR1 and PDE2 PMCID:    Pubmed No.:30509171 Dl-3-N-Butylphthalide Alleviates the Blood–Brain Barrier Permeability of Focal Cerebral Ischemia Reperfusion in Mice PMCID:    Pubmed No.:31247236 A novel oleanolic acid derivative HA-19 ameliorates muscle atrophy via promoting protein synthesis and preventing protein degradation PMCID:    Pubmed No.:31201822 Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats PMCID:    Pubmed No.:29729281 Fluoride induces apoptosis via inhibiting SIRT1 activity to activate mitochondrial p53 pathway in human neuroblastoma SH-SY5Y cells PMCID:    Pubmed No.:29609003 Induction of apoptosis in hematological cancer cells by dorsomorphin correlates with BAD upregulation PMCID:    Pubmed No.:31787232 CDK5 Functions as a Tumor Promoter in Human Lung Cancer PMCID:    Pubmed No.:30410599 Pristimerin induces apoptosis and inhibits proliferation, migration in H1299 Lung Cancer Cells PMCID:    Pubmed No.:33033518 Liraglutide activates nature killer cell-mediated antitumor responses by inhibiting IL-6/STAT3 signaling in hepatocellular carcinoma PMCID:    Pubmed No.:32979685 Downregulation of TNF-α/TNF-R1 Signals by AT-Lipoxin A4 May Be a Significant Mechanism of Attenuation in SAP-Associated Lung Injury PMCID:    Pubmed No.:31097921 miR-486 Promotes Capan-2 Pancreatic Cancer Cell Proliferation by Targeting Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) PMCID:    Pubmed No.:31258546 Different effects of anti-VEGF drugs (Ranibizumab, Aflibercept, Conbercept) on autophagy and its effect on neovascularization in RF/6A cells PMCID:    Pubmed No.:34119535 FABP4 accelerates glioblastoma cell growth and metastasis through Wnt10b signalling. PMCID:    Pubmed No.:30536325 The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition PMCID:    Pubmed No.:30826420 Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat PMCID:    Pubmed No.:30172000 Diminished CD68+ Cancer-Associated Fibroblast Subset Induces Regulatory T-Cell (Treg) Infiltration and Predicts Poor Prognosis of Oral Squamous Cell Carcinoma Patients PMCID:    Pubmed No.:32035062 Mechanical Strain Induces Distinct Human Scleral Fibroblast Lineages: Differential Roles in Cell Proliferation, Apoptosis, Migration, and Differentiation PMCID:    Pubmed No.:29847646 Gastric-cancer-derived mesenchymal stem cells: a promising target for resveratrol in the suppression of gastric cancer metastasis PMCID:    Pubmed No.:32350750 Sorting nexin 11 knockout mice exhibit enhanced thermosensing behaviour PMCID:    Pubmed No.:31730264 Hypoxia‐induced ARHGAP26 deficiency inhibits the proliferation and migration of human ductus arteriosus smooth muscle cell through activating RhoA‐ROCK‐PTEN pathway PMCID:    Pubmed No.:30592323 The effects of parathyroid hormone‐related peptide on cardiac angiogenesis, apoptosis, and function in mice with myocardial infarction PMCID:    Pubmed No.:30994964 Xiao Ke Qing improves glycometabolism and ameliorates insulin resistance by regulating the PI3K/Akt pathway in KKAy mice PMCID:    Pubmed No.:30421394 Costunolide induces apoptosis and inhibits migration and invasion in H1299 lung cancer cells PMCID:    Pubmed No.:32236584 Ribes diacanthum Pall (RDP) ameliorates UUO-induced renal fibrosis via both canonical and non-canonical TGF-β signaling pathways in mice PMCID:    Pubmed No.:30342194 PCB118 Induces Inflammation of Islet Beta Cells via Activating ROS-NLRP3 Inflammasome Signaling PMCID:    Pubmed No.:34055976 Gene expression in human umbilical vein endothelial cells exposed to fine particulate matter: RNA sequencing analysis PMCID:    Pubmed No.:34102927 Amyloid-β1-42 dynamically regulates the migration of neural stem/progenitor cells via MAPK-ERK pathway PMCID:    Pubmed No.:30399361 Inhibition of DNMT suppresses the stemness of colorectal cancer cells through down-regulating Wnt signaling pathway PMCID:    Pubmed No.:29601907 HASPIN is involved in the progression of gallbladder carcinoma PMCID:    Pubmed No.:31987787 Knockdown of ALPK2 blocks development and progression of renal cell carcinoma PMCID:    Pubmed No.:32330508 Mitoferrin 2 deficiency prevents mitochondrial iron overload-induced endothelial injury and alleviates atherosclerosis PMCID:    Pubmed No.:33711329 Babaodan inhibits cell growth by inducing autophagy through the PI3K/AKT/mTOR pathway and enhances antitumor effects of cisplatin in NSCLC cells PMCID:    Pubmed No.:31497240 Trimethylamine N-Oxide Exacerbates Cardiac Fibrosis via Activating the NLRP3 Inflammasome PMCID:    Pubmed No.:31354519 Autoinducer-2 of Fusobacterium nucleatum promotes macrophage M1 polarization via TNFSF9/IL-1β signaling PMCID:    Pubmed No.:31272064 Vitamin D alleviates airway remodeling in asthma by down-regulating the activity of Wnt/β-catenin signaling pathway PMCID:    Pubmed No.:30616171 Epidermal growth factor‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1) suppressed the growth of hepatocellular carcinoma cells by promoting Semaphorin 3B(SEMA3B) PMCID:    Pubmed No.:30972979 Effect of pre-slaughter shackling and wing flapping on plasma parameters, postmortem metabolism, AMPK, and meat quality of broilers PMCID:    Pubmed No.:29462466 Roles of chicken growth hormone receptor antisense transcript in chicken muscle development and myoblast differentiation PMCID:    Pubmed No.:31376348 6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction PMCID:    Pubmed No.:30408433 THAP7 promotes cell proliferation by regulating the G1/S phase transition via epigenetically silencing p21 in lung adenocarcinoma PMCID:    Pubmed No.:31372002 Resveratrol Reverses Cigarette Smoke-Induced Urocystic Epithelial–Mesenchymal Transition via Suppression of STAT3 Phosphorylation in SV-HUC-1-Immortalized Human Urothelial Cells PMCID:    Pubmed No.:32063715 CD4+ CD25+ regulatory T cells promote hepatocellular carcinoma invasion via TGF-β1-induced epithelial–mesenchymal transition PMCID:    Pubmed No.:30643426 SOX5 promotes cell invasion and metastasis via activation of Twist-mediated epithelial–mesenchymal transition in gastric cancer PMCID:    Pubmed No.:31040690 DEP Domain-Containing Protein 1B (DEPDC1B) Promotes Migration and Invasion in Pancreatic Cancer Through the Rac1/PAK1-LIMK1-Cofilin1 Signaling Pathway PMCID:    Pubmed No.:32110046 PFND1 Predicts Poor Prognosis of Gastric Cancer and Promotes Cell Metastasis by Activating the Wnt/β-Catenin Pathway PMCID:    Pubmed No.:32368077 p70S6K Promotes Acquired Resistance of Erlotinib Through Induction of Epithelial-Mesenchymal Transition in Non-Small Cell Lung Carcinoma PMCID:    Pubmed No.:32606745 CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial– mesenchymal transition PMCID:    Pubmed No.:30288051 CPEB4 promotes growth and metastasis of gastric cancer cells via ZEB1-mediated epithelial– mesenchymal transition PMCID:    Pubmed No.:30288051 Polygalaxanthone III downregulates inflammation in the lipopolysaccharide-stimulated RAW264.7 macrophages: A quantibody array analysis PMCID:    Pubmed No.:34384566 SPIO nanoparticle-labeled bone marrow mesenchymal stem cells inhibit pulmonary EndoMT induced by SiO2 PMCID:    Pubmed No.:31291564 Induction of Macrophage M2b/c Polarization by Adipose Tissue-Derived Mesenchymal Stem Cells PMCID:    Pubmed No.:31321244 Angiotensin-(1-7) induced vascular relaxation in spontaneously hypertensive rats PMCID:    Pubmed No.:30880106 Lamprey PHB2 maintains mitochondrial stability by tanslocation to the mitochondria under oxidative stress PMCID:    Pubmed No.:32592929 Dynein- and kinesin- mediated intracellular transport on microtubules facilitates RABV infection PMCID:    Pubmed No.:34555731 ZC3H4 mediates silica-induced EndoMT via ER stress and autophagy PMCID:    Pubmed No.:33545378 Inhibition of glioma growth by a GOLPH3 siRNA-loaded cationic liposomes PMCID:    Pubmed No.:30105446 HSC-specific knockdown of GGPPS alleviated CCl4-induced chronic liver fibrosis through mediating RhoA/Rock pathway PMCID:    Pubmed No.:31105844 Aesculin protects against DSS-Induced colitis though activating PPARγ and inhibiting NF-кB pathway PMCID:    Pubmed No.:31202807 Auranofin lethality to prostate cancer includes inhibition of proteasomal deubiquitinases and disrupted androgen receptor signaling PMCID:    Pubmed No.:30639309 Metformin and MiR-365 synergistically promote the apoptosis of gastric cancer cells via MiR-365-PTEN-AMPK axis PMCID:    Pubmed No.:35007850 Integrated Network Pharmacology Analysis and Pharmacological Evaluation to Explore the Active Components and Mechanism of Abelmoschus manihot (L.) Medik. on Renal Fibrosis PMCID:    Pubmed No.:33061308 Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway PMCID:    Pubmed No.:31849446 N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury PMCID:    Pubmed No.:30584276 Chloroquine and 3-Methyladenine Attenuates Periodontal Inflammation and Bone Loss in Experimental Periodontitis PMCID:    Pubmed No.:31720989 Cyclin-Dependent Kinase 9 Inhibition Suppresses Necroptosis and Pyroptosis in the Progress of Endotoxemia PMCID:    Pubmed No.:32556803 Segmented scan modes and polarity-based LC-MS for pharmacokinetic interaction study between Fufang Danshen Dripping Pill and Clopidogrel Bisulfate Tablet PMCID:    Pubmed No.:31202879 Neuroprotective effects of ZL006 in Aβ1–42-treated neuronal cells PMCID:    Pubmed No.:32594052 IRS-1 targets TAZ to inhibit adipogenesis of rat bone marrow mesenchymal stem cells through PI3K-Akt and MEK-ERK pathways PMCID:    Pubmed No.:30716312 TEKT4 Promotes Papillary Thyroid Cancer Cell Proliferation, Colony Formation, and Metastasis through Activating PI3K/Akt Pathway PMCID:    Pubmed No.:30251060 ALDH1A3 serves as a predictor for castration resistance in prostate cancer patients PMCID:    Pubmed No.:32375698 Behavioral Abnormality along with NMDAR-related CREB Suppression in Rat Hippocampus after Shortwave Exposure PMCID:    Pubmed No.:30987693 AKAP12 Endogenous Transcripts Suppress The Proliferation, Migration And Invasion Of Colorectal Cancer Cells By Directly Targeting oncomiR-183-5p PMCID:    Pubmed No.:31632079 TRIM37 promotes cell invasion and metastasis by regulating SIP1-mediated epithelial–mesenchymal transition in gastric cancer PMCID:    Pubmed No.:30573971 Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression PMCID:    Pubmed No.:30613152 Transcobalamin I: a novel prognostic biomarker of neoadjuvant chemotherapy in locally advanced hypopharyngeal squamous cell cancers PMCID:    Pubmed No.:30100732 miR‑498 inhibits the growth and metastasis of liver cancer by targeting ZEB2 PMCID:    Pubmed No.:30592286 β‑carotene reverses tobacco smoke‑induced gastric EMT via Notch pathway in vivo PMCID:    Pubmed No.:29393400 Ketone Metabolite β-Hydroxybutyrate Ameliorates Inflammation After Spinal Cord Injury by Inhibiting the NLRP3 Inflammasome PMCID:    Pubmed No.:33108630 PKC Mediates LPS-Induced IL-1β Expression and Participates in the Pro-inflammatory Effect of A 2A R Under High Glutamate Concentrations in Mouse Microglia PMCID:    Pubmed No.:31650360 Cytological and spectroscopic characteristics of c‐KIT N822K mutation in core binding factor acute myeloid leukemia cells PMCID:    Pubmed No.:32390317 Repurposing bortezomib for choroidal neovascularization treatment via antagonizing VEGF-A and PDGF-D mediated signaling PMCID:    Pubmed No.:33476605 Modulation of gut microbiota contributes to effects of intensive insulin therapy on intestinal morphological alteration in high-fat-diet-treated mice PMCID:    Pubmed No.:31749050 RNPS1 inhibition aggravates ischemic brain injury and promotes neuronal death PMCID:    Pubmed No.:31831174 MiR-139-5p suppresses osteosarcoma cell growth and invasion through regulating DNMT1 PMCID:    Pubmed No.:29673587 Metformin promotes the osseointegration of titanium implants under osteoporotic conditions by regulating BMSCs autophagy, and osteogenic differentiation PMCID:    Pubmed No.:32800340 Ran participates in deltamethrin stress through regulating the nuclear import of Nrf2 PMCID:    Pubmed No.:33069802 Overinhibition mediated by parvalbumin interneurons might contribute to depression-like behavior and working memory impairment induced by lipopolysaccharide challenge PMCID:    Pubmed No.:31987933 Inhibition of Dishevelled‑2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β‑catenin signaling PMCID:    Pubmed No.:34589148 Study on Association of Pentraxin 3 and Diabetic Nephropathy in a Rat Model PMCID:    Pubmed No.:29725602 Salidroside inhibits endothelial‑mesenchymal transition via the KLF4/eNOS signaling pathway PMCID:    Pubmed No.:34368873 Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats PMCID:    Pubmed No.:33786621 LINC00461/miR-4478/E2F1 feedback loop promotes non-small cell lung cancer cell proliferation and migration PMCID:    Pubmed No.:31934717 BMP9 exhibits dual and coupled roles in inducing osteogenic and angiogenic differentiation of mesenchymal stem cells PMCID:    Pubmed No.:32478395 Leptin-induced inflammation by activating IL-6 expression contributes to the fibrosis and hypertrophy of ligamentum flavum in lumbar spinal canal stenosis PMCID:    Pubmed No.:29436483 TGF-β1 induces epithelial-to-mesenchymal transition via inhibiting mitochondrial functions in A549 cells PMCID:    Pubmed No.:30203703 Xingnaojing ameliorates synaptic plasticity and memory deficits in an Aβ1–42 induced mouse model of Alzheimer's disease PMCID:    Pubmed No.:32482409 Chinese medicine Di-Huang-Yi-Zhi protects PC12 cells from H 2 O 2 -induced apoptosis by regulating ROS-ASK1-JNK/p38 MAPK signaling PMCID:    Pubmed No.:32059723 Oridonin inhibits metastasis of human ovarian cancer cells by suppressing the mTOR pathway PMCID:    Pubmed No.:31360196 Overexpression of CTRP9 attenuates the development of atherosclerosis in apolipoprotein E-deficient mice PMCID:    Pubmed No.:30426302 Sodium butyrate improves antioxidant stability in sub-acute ruminal acidosis in dairy goats PMCID:    Pubmed No.:30200953 RhoA protects the podocytes against high glucose-induced apoptosis through YAP and plays critical role in diabetic nephropathy PMCID:    Pubmed No.:30220545 Betaine improves the growth performance and muscle growth of partridge shank broiler chickens via altering myogenic gene expression and insulin-like growth factor-1 signaling pathway PMCID:    Pubmed No.:30085311 Golgi Membrane Protein 1 (GOLM1) Promotes Growth and Metastasis of Breast Cancer Cells via Regulating Matrix Metalloproteinase-13 (MMP13) PMCID:    Pubmed No.:30695018 Andrographolide Inhibition of Th17-Regulated Cytokines and JAK1/STAT3 Signaling in OVA-Stimulated Asthma in Mice PMCID:    Pubmed No.:34194525 Identification of Goose PKR Gene: Structure, Expression Profiling, and Antiviral Activity Against Newcastle Disease Virus PMCID:    Pubmed No.:30052119 Higenamine Improves Cardiac and Renal Fibrosis in Rats With Cardiorenal Syndrome via ASK1 Signaling Pathway PMCID:    Pubmed No.:32168151 Entry of Challenge Virus Standard (CVS) -11 into N2a cells via a clathrin-mediated, cholesterol-, dynamin-, pH-dependent endocytic pathway PMCID:    Pubmed No.:31196105 HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma PMCID:    Pubmed No.:33559901 Knockdown of Kinesin Family 15 Inhibits Osteosarcoma through Suppressing Cell Proliferation and Promoting Cell Apoptosis PMCID:    Pubmed No.:32074608 MiR-218-5p targets LHFPL3 to regulate proliferation, migration, and epithelial–mesenchymal transitions of human glioma cells PMCID:    Pubmed No.:30314994 Effects of CD100 promote wound healing in diabetic mice PMCID:    Pubmed No.:29637382 α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling PMCID:    Pubmed No.:30972697 Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity PMCID:    Pubmed No.:32669967 LncRNA SNHG1 promotes EMT process in gastric cancer cells through regulation of the miR-15b/DCLK1/Notch1 axis. PMCID:    Pubmed No.:32423385 A novel rat model of seminal vesiculitis PMCID:    Pubmed No.:30460934 Perfluorooctane sulfonate induces heart toxicity involving cardiac apoptosis and inflammation in rats PMCID:    Pubmed No.:34815766 Hydrogen gas alleviates acute alcohol‑induced liver injury by inhibiting JNK activation PMCID:    Pubmed No.:33767761 Cocaine- and amphetamine-regulated transcript protects synaptic structures in neurons after ischemic cerebral injury PMCID:    Pubmed No.:32005500 Mitochondrial ATP-Sensitive K+ Channel Opening Increased the Airway Smooth Muscle Cell Proliferation by Activating the PI3K/AKT Signaling Pathway in a Rat Model of Asthma PMCID:    Pubmed No.:34336047 Tetrandrine alleviates cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via Sirt-1 PMCID:    Pubmed No.:32419986 microRNA-29b prevents renal fibrosis by attenuating renal tubular epithelial cell–mesenchymal transition through targeting the PI3K/AKT pathway PMCID:    Pubmed No.:33742315 Effect of Heat Treatment on the Anticancer Activity of Houttuynia cordata Thunb Aerial Stem Extract in Human Gastric Cancer SGC-7901 Cells PMCID:    Pubmed No.:32180441 Halofuginone inhibits tumorigenic progression of 5‑FU‑resistant human colorectal cancer HCT‑15/FU cells by targeting miR‑132‑3p in vitro PMCID:    Pubmed No.:33154782 Knockdown of neuron‑specific enolase suppresses the proliferation and migration of NCI‑H209 cells PMCID:    Pubmed No.:31611991 Antitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF‑κB/caspase‑3 signaling pathways PMCID:    Pubmed No.:30333875 Konjac glucomannan reverses multi‑drug resistance of HepG2/5‑FU cells by suppressing AKT signaling and increasing p53 expression PMCID:    Pubmed No.:32782527 Fluvastatin-Pretreated Donor Cells Attenuated Murine aGVHD by Balancing Effector T Cell Distribution and Function under the Regulation of KLF2 PMCID:    Pubmed No.:33415155 Decreased Endometrial IL-10 Impairs Endometrial Receptivity by Downregulating HOXA10 Expression in Women with Adenomyosis PMCID:    Pubmed No.:30687738 Yunnan Baiyao Conditioned Medium Promotes the Odonto/Osteogenic Capacity of Stem Cells from Apical Papilla via Nuclear Factor Kappa B Signaling Pathway PMCID:    Pubmed No.:31179335 Effects of long-term rapamycin treatment on glial scar formation after cryogenic traumatic brain injury in mice PMCID:    Pubmed No.:29727731 Evodiamine inhibits vasculogenic mimicry in HCT116 cells by suppressing hypoxia-inducible factor 1-alpha-mediated angiogenesis PMCID:    Pubmed No.:33394687 SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis PMCID:    Pubmed No.:30349378 CNOT7 depletion reverses natural killer cell resistance by modulating the tumor immune microenvironment of hepatocellular carcinoma PMCID:    Pubmed No.:32160402 Leptin-regulated autophagy plays a role in long-term neurobehavioral injury after neonatal seizures and the regulation of zinc/cPLA2 and CaMK II signaling in cerebral cortex PMCID:    Pubmed No.:30092488 -Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells PMCID:    Pubmed No.:30363706 -Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells PMCID:    Pubmed No.:30363706 A Novel Cerebroprotein Hydrolysate, CH1, Ameliorates Chronic Focal Cerebral Ischemia Injury by Promoting White Matter Integrity via the Shh/Ptch-1/Gli-1 Signaling Pathway PMCID:    Pubmed No.:33380798 Sustained activation of C3aR in a human podocyte line impairs the morphological maturation of the cells PMCID:    Pubmed No.:33174024 Synergistic anticancer effects of bufalin and sorafenib by regulating apoptosis associated proteins PMCID:    Pubmed No.:29693132 Mild hypothermia reduces endoplasmic reticulum stress‐induced apoptosis and improves neuronal functions after severe traumatic brain injury PMCID:    Pubmed No.:30834702 The GLP-1/GIP dual-receptor agonist DA5-CH inhibits the NF-κB inflammatory pathway in the MPTP mouse model of Parkinson's disease more effectively than the GLP-1 single-receptor agonist NLY01 PMCID:    Pubmed No.:34125470 Protective role of berberine in isoprenaline-induced cardiac fibrosis in rats PMCID:    Pubmed No.:31615408 Sorafenib blocks the activation of the HIF-2α/VEGFA/EphA2 pathway, and inhibits the rapid growth of residual liver cancer following high-intensity focused ultrasound therapy in vivo PMCID:    Pubmed No.:33640712 Salvianolic acid A inhibits tumor-associated angiogenesis by blocking GRP78 secretion PMCID:    Pubmed No.:30560355 LncRNA linc00460 sponges miR-1224-5p to promote esophageal cancer metastatic potential and epithelial-mesenchymal transition PMCID:    Pubmed No.:32534700 Angiotensin-(1-9) ameliorates pulmonary arterial hypertension via angiotensin type II receptor PMCID:    Pubmed No.:29962859 Glucose-Related Protein 78 Expression and Its Effects on Cisplatin-Resistance in Cervical Cancer PMCID:    Pubmed No.:29650944 Effects of bradykinin on the survival of multiterritory perforator flaps in rats PMCID:    Pubmed No.:30813916 IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells PMCID:    Pubmed No.:30530508 Nur77 promotes embryo adhesion by transcriptionally regulating HOXA10 expression PMCID:    Pubmed No.:31574241 Aqueous extract of Chrysanthemum morifolium Ramat. inhibits RANKL-induced osteoclast differentiation by suppressing the c-fos/NFATc1 pathway PMCID:    Pubmed No.:33387850 In Vitro Expression of Cytokeratin 19 in Adipose-Derived Stem Cells Is Induced by Epidermal Growth Factor PMCID:    Pubmed No.:29925829 RANK Deficiency Ameliorates Podocyte Injury by Suppressing Calcium/Calcineurin/ NFATc1 Signaling PMCID:    Pubmed No.:30036881 Liriodenine enhances radiosensitivity in esophageal cancer ECA‑109 cells by inducing apoptosis and G2/M arrest PMCID:    Pubmed No.:30250568 L-Theanine Down-Regulates the JAK/STAT3 Pathway to Attenuate the Proliferation and Migration of Vascular Smooth Muscle Cells Induced by Angiotensin II PMCID:    Pubmed No.:30381668 EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer PMCID:    Pubmed No.:29620175 Inhibition of autophagy after perforator flap surgery increases flap survival and angiogenesis PMCID:    Pubmed No.:30278973 Involvement of hypoxia-inducible factor-1 alpha in the upregulation of P-glycoprotein in refractory epilepsy PMCID:    Pubmed No.:31634239 Malonic acid suppresses lipopolysaccharide-induced BV2 microglia cell activation by inhibiting the p38 MAPK/NF-κB pathway PMCID:    Pubmed No.:34234892 Neferine Exerts Antioxidant and Anti-Inflammatory Effects on Carbon Tetrachloride-Induced Liver Fibrosis by Inhibiting the MAPK and NF-κB/IκBα Pathways PMCID:    Pubmed No.:33680053 Xiao-Yao-San Formula Improves Cognitive Ability by Protecting the Hippocampal Neurons in Ovariectomized Rats PMCID:    Pubmed No.:32655660 Si-Wu-Tang Alleviates Nonalcoholic Fatty Liver Disease via Blocking TLR4-JNK and Caspase-8-GSDMD Signaling Pathways PMCID:    Pubmed No.:32849904 MicroRNA‑9 inhibits gastric cancer cell proliferation and migration by targeting neuropilin‑1 PMCID:    Pubmed No.:31572503 Blocking of BDNF-TrkB signaling inhibits the promotion effect of neurological function recovery after treadmill training in rats with spinal cord injury PMCID:    Pubmed No.:30002472 Ginkgolide B improves multiterritory perforator flap survival by inhibiting endoplasmic reticulum stress and oxidative stress PMCID:    Pubmed No.:31870195 Effects of dietary supplementation with betaine on muscle growth, muscle amino acid contents and meat quality in Cherry Valley ducks PMCID:    Pubmed No.:31140661 Silencing of Proteasome 26S Subunit ATPase 2 Regulates Colorectal Cancer Cell Proliferation, Apoptosis, and Migration PMCID:    Pubmed No.:31715603 Advanced oxidation protein products inhibit the autophagy of renal tubular epithelial cells PMCID:    Pubmed No.:29556265 Long Noncoding RNA EGFR-AS1 Promotes Cell Proliferation by Increasing EGFR mRNA Stability in Gastric Cancer PMCID:    Pubmed No.:30138934 Inhibition of Proteasomal Deubiquitinase by Silver Complex Induces Apoptosis in Non-Small Cell Lung Cancer Cells PMCID:    Pubmed No.:30165348 Deubiquitinase Inhibitor Auranofin Attenuated Cardiac Hypertrophy by Blocking NF-κB Activation PMCID:    Pubmed No.:29554646 Autophagy Facilitates Metadherin-Induced Chemotherapy Resistance Through the AMPK/ATG5 Pathway in Gastric Cancer PMCID:    Pubmed No.:29635244 Enhanced nuclear localization of YAP1-2 contributes to EGF-induced EMT in NSCLC PMCID:    Pubmed No.:35014181 ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive feedback loop PMCID:    Pubmed No.:34979141 Proline-rich transmembrane protein 2 specifically binds to GluA1 but has no effect on AMPA receptor-mediated synaptic transmission PMCID:    Pubmed No.:34997978 Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2 PMCID:    Pubmed No.:35326233 The cardiotoxicity of asthmatic rats after traffic-related PM2.5 and water-soluble components exposure mediated by endoplasmic reticulum stress and autophagy PMCID:    Pubmed No.:35235115 Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways PMCID:    Pubmed No.:35307375 Prohibitin Protects Pulmonary Microvascular Endothelial Cells Against Cigarette Smoke Extract-Induced Cell Apoptosis and Inflammation PMCID:    Pubmed No.:35378837 Brown adipose tissue involution associated with progressive restriction in progenitor competence PMCID:    Pubmed No.:35417710 Upregulation of COPB2 Promotes Prostate Cancer Proliferation and Invasion Through the MAPK/TGF-β Signaling Pathway PMCID:    Pubmed No.:35600351 Phytoestrogen arctigenin preserves the mucus barrier in inflammatory bowel diseases by inhibiting goblet cell apoptosis via the ERβ/TRIM21/PHB1 pathway PMCID:    Pubmed No.:35599350 Contribution of Amygdala Histone Acetylation in Early Life Stress-Induced Visceral Hypersensitivity and Emotional Comorbidity PMCID:    Pubmed No.:35600618 Knockout of cyclin B1 in granulosa cells causes female subfertility PMCID:    Pubmed No.:35536551 Chemical characteristics of Rhodiola Crenulata and its mechanism in acute mountain sickness using UHPLC-Q-TOF-MS/MS combined with network pharmacology analysis PMCID:    Pubmed No.:35526732 METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma PMCID:    Pubmed No.:35856434 YAP9/A20 complex suppresses proinflammatory responses and provides novel anti-inflammatory therapeutic potentials. PMCID:    Pubmed No.:36045678 ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10 PMCID:    Pubmed No.:35962397 Rapamycin inhibits hepatitis B virus covalently closed circular DNA transcription by enhancing the ubiquitination of HBx PMCID:    Pubmed No.:36033851 Around-the-Clock Noise Induces AD-like Neuropathology by Disrupting Autophagy Flux Homeostasis PMCID:    Pubmed No.:36078149 Reduced N6-methyladenosine mediated by METTL3 acetylation promotes MTF1 expression and hepatocellular carcinoma cell growth PMCID:    Pubmed No.:36149370 Tabersonine alleviates obesity-induced cardiomyopathy by binding to Transforming growth factor activated kinase 1 (TAK1) and inhibiting TAK1-mediated inflammation PMCID:    Pubmed No.:36420902 A splicing-dependent ER retention signal regulates surface expression of the mechanosensitive TMEM63B cation channel PMCID:    Pubmed No.:36496074 Effects of Cinobufagin on the Proliferation, Migration, and Invasion of H1299 Lung Cancer Cells PMCID:    Pubmed No.:36522286 Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects PMCID:    Pubmed No.:36690096 Adipose-Derived Mesenchymal Stem Cells Inhibit JNK-Mediated Mitochondrial Retrograde Pathway to Alleviate Acetaminophen-Induced Liver Injury PMCID:    Pubmed No.:36671020 The effect of regulating MCU expression on experimental ischemic brain injury PMCID:    Pubmed No.:36702427 Huangkui capsule alleviates adriamycin-induced proteinuria via protecting against podocyte damage and inhibiting JAK/STAT signaling PMCID:    Pubmed No.:36608778 Bicyclol Alleviates Streptozotocin-induced Diabetic Cardiomyopathy By Inhibiting Chronic Inflammation And Oxidative Stress PMCID:    Pubmed No.:36662448 IBV QX affects the antigen presentation function of BMDCs through non-structural protein16 PMCID:    Pubmed No.:36972672 USP25 inhibits renal fibrosis by regulating TGFβ-SMAD signaling pathway in Ang II-induced hypertensive mice PMCID:    Pubmed No.:37059312 AURKB Enhances Chromosomal Remodeling of Telomeric Genes and Accelerates Tumorigenesis of Uveal Melanoma PMCID:    Pubmed No.:37079315 CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation PMCID:    Pubmed No.:37210387 1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway PMCID:    Pubmed No.:37380045 SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression PMCID:    Pubmed No.:37525212 USP25 Inhibits Neuroinflammatory Responses After Cerebral Ischemic Stroke by Deubiquitinating TAB2 PMCID:    Pubmed No.:37587766 OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6 PMCID:    Pubmed No.:37608493 USP25 ameliorates diabetic nephropathy by inhibiting TRAF6-mediated inflammatory responses PMCID:    Pubmed No.:37657242 PCSK9 causes inflammation and cGAS/STING pathway activation in diabetic nephropathy PMCID:    Pubmed No.:37561547 Hydrogen Sulfide Prevents LPS-Induced Depression-like Behavior through the Suppression of NLRP3 Inflammasome and Pyroptosis and the Improvement of Mitochondrial Function in the Hippocampus of Mice PMCID:    Pubmed No.:37626978 ETV5 facilitates tumor progression in head-neck squamous cell carcinoma PMCID:    Pubmed No.:37649213 Cold-inducible PPA1 is critical for the adipocyte browning in mice PMCID:    Pubmed No.:37549601 Water extract of frankincense and myrrh inhibits liver cancer progression and epithelial‑mesenchymal transition through Wnt/β‑catenin signaling PMCID:    Pubmed No.:37719039 ZC3H4 governs epithelial cell migration through ROCK/p-PYK2/p-MLC2 pathway in silica-induced pulmonary fibrosis PMCID:    Pubmed No.:37866415
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
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