Bamboo leaf extract ameliorates diabetic nephropathy through activating the AKT signaling pathway in rats PMCID:    Pubmed No.:28359892 Multisite mutation of monomer survivin with enhanced effect on apoptosis regulation of breast cancer cells PMCID:    Pubmed No.:25661346 Design, synthesis and in vitro evaluation of novel ursolic acid derivatives as potential anticancer agents PMCID:    Pubmed No.:25841199 Long non-coding RNA LINC00968 acts as oncogene in NSCLC by activating the Wnt signaling pathway PMCID:    Pubmed No.:28926089 MicroRNA‐146b, a Sensitive Indicator of Mesenchymal Stem Cell Repair of Acute Renal Injury PMCID:    Pubmed No.:27400799 Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor PMCID:    Pubmed No.:28151478 miR-181a increases FoxO1 acetylation and promotes granulosa cell apoptosis via SIRT1 downregulation PMCID:    Pubmed No.:28981116 1,5-dicaffeoylquinic acid protects primary neurons from amyloid β1-42-induced apoptosis via PI3K/Akt signaling pathway PMCID:    Pubmed No.:22040415 Protective effect of recombinant hirudin variant III against galactose-mediated rat lens epithelial cell damage PMCID:    Pubmed No.:22335805 Neuroprotective effects of anti-tumor necrosis factor-alpha antibody on apoptosis following subarachnoid hemorrhage in a rat model PMCID:    Pubmed No.:22516550 Altered expression of mitofusin 2 in penile tissues of diabetic rats PMCID:    Pubmed No.:23682852 CSE/H2S system protects mesenchymal stem cells from hypoxia and serum deprivation‑induced apoptosis via mitochondrial injury, endoplasmic reticulum stress and PI3K/Akt activation pathways. PMCID:    Pubmed No.:25901909 LZ-106, a novel analog of enoxacin, inducing apoptosis via activation of ROS-dependent DNA damage response in NSCLCs PMCID:    Pubmed No.:27012423 The overexpression and nuclear translocation of Trx-1 during hypoxia confers on HepG2 cells resistance to DDP, and GL-V9 reverses the resistance by suppressing the Trx-1/Ref-1 axis PMCID:    Pubmed No.:25656992 Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53–ROS–Mitochondrial Pathway PMCID:    Pubmed No.:28081741 E2F is involved in radioresistance of carbon ion induced apoptosis via Bax/caspase 3 signal pathway in human hepatoma cell PMCID:    Pubmed No.:28500630 Enhancing the anti-multiple myeloma efficiency in a cancer stem cell xenograft model by conjugating the ABCG2 antibody with microbubbles for a targeted delivery of ultrasound mediated epirubicin PMCID:    Pubmed No.:28232025 Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy PMCID:    Pubmed No.:28388958 High glucose concentration induces endothelial cell proliferation by regulating cyclin‐D2‐related miR‐98 PMCID:    Pubmed No.:26840039 High glucose concentration induces endothelial cell proliferation by regulating cyclin‐D2‐related miR‐98 PMCID:    Pubmed No.:26840039 High glucose concentration induces endothelial cell proliferation by regulating cyclin‐D2‐related miR‐98 PMCID:    Pubmed No.:26840039 Foxc2 enhances proliferation and inhibits apoptosis through activating Akt/mTORC1 signaling pathway in mouse preadipocytes PMCID:    Pubmed No.:26113535 Bound polyphenol from foxtail millet bran induces apoptosis in HCT-116 cell through ROS generation PMCID:    Pubmed No.:34975288 Deferoxamine pre-treatment protects against postoperative cognitive dysfunction of aged rats by depressing microglial activation via ameliorating iron accumulation in hippocampus PMCID:    Pubmed No.:27608977 The neuroprotective effect of a novel agent N2 on rat cerebral ischemia associated with the activation of PI3K/Akt signaling pathway PMCID:    Pubmed No.:25725335 HucMSC exosome-transported 14-3-3ζ prevents the injury of cisplatin to HK-2 cells by inducing autophagy in vitro PMCID:    Pubmed No.:28943243 Alpinetin inhibits lung cancer progression and elevates sensitization drug-resistant lung cancer cells to cis-diammined dichloridoplatium PMCID:    Pubmed No.:26604699 Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents PMCID:    Pubmed No.:27138035 Triptolide induces Sertoli cell apoptosis in mice via ROS/JNK-dependent activation of the mitochondrial pathway and inhibition of Nrf2-mediated antioxidant response PMCID:    Pubmed No.:28905938 Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects of the mTOR Inhibitor Everolimus against Melanoma PMCID:    Pubmed No.:28054548 The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy PMCID:    Pubmed No.:29277549 Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Acute Myocardial Ischemic Injury PMCID:    Pubmed No.:26106430 Inhibition of lung cancer in diethylnitrosamine‐induced mice by Rhizoma paridis saponins PMCID:    Pubmed No.:27991692 Study on the mechanism of AMPK signaling pathway and its effect on apoptosis of human hepatocellular carcinoma SMMC-7721 cells by curcumin. PMCID:    Pubmed No.:28338175 NOAD, a novel nitric oxide donor, induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma Bel-7402 cells PMCID:    Pubmed No.:26001517 MCM2 is a therapeutic target of lovastatin in human non-small cell lung carcinomas PMCID:    Pubmed No.:25738322 Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate PMCID:    Pubmed No.:26523278 Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice PMCID:    Pubmed No.:26064905 Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway PMCID:    Pubmed No.:28734031 Synthesis, antiproliferative and apoptosis-inducing effects of novel asiatic acid derivatives containing α-aminophosphonates PMCID:    Pubmed No.:24262379 Curcumin-cyclodextrin complexes enhanced the anti-cancer effects of curcumin PMCID:    Pubmed No.:27716533 A novel dual GLP-1 and GIP receptor agonist is neuroprotective in the MPTP mouse model of Parkinson′s disease by increasing expression of BNDF PMCID:    Pubmed No.:26453833 Study on the mitochondrial apoptosis pathways of small cell lung cancer H446 cells induced by Trichinella spiralis muscle larvae ESPs PMCID:    Pubmed No.:28073393 Electroacupuncture improves neurobehavioral function and brain injury in rat model of intracerebral hemorrhage PMCID:    Pubmed No.:28395933 Early applied electric field stimulation attenuates secondary apoptotic responses and exerts neuroprotective effects in acute spinal cord injury of rats PMCID:    Pubmed No.:25701712 Clostridium butyricum pretreatment attenuates cerebral ischemia/reperfusion injury in mice via anti-oxidation and anti-apoptosis PMCID:    Pubmed No.:26733300 Exogenous Adipokine Peptide Resistin Protects Against Focal Cerebral Ischemia/Reperfusion Injury in Mice PMCID:    Pubmed No.:28608237 Protective Effect of l -Theanine on Cadmium-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondria-Mediated Pathway PMCID:    Pubmed No.:26164708 Upregulated long non-coding RNA LOC90784 promotes cell proliferation and invasion and is associated with poor clinical features in HCC PMCID:    Pubmed No.:28651931 Melatonin protects against chronic intermittent hypoxia-induced cardiac hypertrophy by modulating autophagy through the 5′ adenosine monophosphate-activated protein kinase pathway PMCID:    Pubmed No.:26188509 FK506 protects heart function via increasing autophagy after myocardial infarction in mice PMCID:    Pubmed No.:28965948 Annosquacin B induces mitochondrial apoptosis in multidrug resistant human breast cancer cell line MCF-7/ADR through selectively modulating MAPKs pathways PMCID:    Pubmed No.:27450387 Activation of cellular apoptosis in the caecal epithelium is associated with increased oxidative reactions in lactating goats after feeding a high-concentrate diet PMCID:    Pubmed No.:25590230 MiR-320a effectively suppresses lung adenocarcinoma cell proliferation and metastasis by regulating STAT3 signals PMCID:    Pubmed No.:28106481 Suppression of murine experimental autoimmune encephalomyelitis development by 1,25-dihydroxyvitamin D3 with autophagy modulation PMCID:    Pubmed No.:25773147 Protective Efficacy of Vitamins C and E on p,p′-DDT-Induced Cytotoxicity via the ROS-Mediated Mitochondrial Pathway and NF-κB/FasL Pathway PMCID:    Pubmed No.:25464339 The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway PMCID:    Pubmed No.:26571038 A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model PMCID:    Pubmed No.:28342971 β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway PMCID:    Pubmed No.:28481901 NFBD1/MDC1 participates in the regulation of proliferation and apoptosis in human laryngeal squamous cell carcinoma PMCID:    Pubmed No.:28921460 miR‐1273g‐3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV‐related liver fibrosis PMCID:    Pubmed No.:27423040 Downregulation of angiogenin inhibits the growth and induces apoptosis in human bladder cancer cells through regulating AKT/mTOR signaling pathway PMCID:    Pubmed No.:25564356 Depleted aldehyde dehydrogenase 1A1 (ALDH1A1) reverses cisplatin resistance of human lung adenocarcinoma cell A549/DDP PMCID:    Pubmed No.:27813328 Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy PMCID:    Pubmed No.:27956235 Self-Assembling RADA16-I Peptide Hydrogel Scaffold Loaded with Tamoxifen for Breast Reconstruction PMCID:    Pubmed No.:28691024 CSE/H2S system protects mesenchymal stem cells from hypoxia and serum deprivation‑induced apoptosis via mitochondrial injury, endoplasmic reticulum stress and PI3K/Akt activation pathways PMCID:    Pubmed No.:25901909 Sulforaphane induces p53‑deficient SW480 cell apoptosis via the ROS‑MAPK signaling pathway PMCID:    Pubmed No.:28944886 Glioma targeting peptide in combination with the P53 C terminus inhibits glioma cell proliferation in vitro PMCID:    Pubmed No.:28879517 Promoting effects of IL‑23 on myocardial ischemia and reperfusion are associated with increased expression of IL‑17A and upregulation of the JAK2‑STAT3 signaling pathway PMCID:    Pubmed No.:29039526 Gastrodin prevents steroid-induced osteonecrosis of the femoral head in rats by anti-apoptosis PMCID:    Pubmed No.:30704229 Defective autophagy is associated with neuronal injury in a mouse model of multiple sclerosis PMCID:    Pubmed No.:28086065 Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205 PMCID:    Pubmed No.:27895312 PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells PMCID:    Pubmed No.:27147579 Salinomycin radiosensitizes human nasopharyngeal carcinoma cell line CNE-2 to radiation PMCID:    Pubmed No.:26209294 8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition PMCID:    Pubmed No.:26316083 Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells PMCID:    Pubmed No.:26373733 Osterix Decreases the Chemosensitivity of Breast Cancer Cells by Upregulating GALNT14 PMCID:    Pubmed No.:29227978 miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A PMCID:    Pubmed No.:26023735 Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro PMCID:    Pubmed No.:26707712 Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells PMCID:    Pubmed No.:25394466 Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways PMCID:    Pubmed No.:26503828 Apelin-13 protects against apoptosis by activating AMP-activated protein kinase pathway in ischemia stroke PMCID:    Pubmed No.:26631263 A novel small molecule compound diaporine inhibits breast cancer cell proliferation via promoting ROS generation PMCID:    Pubmed No.:27543689 Costunolide, an active sesquiterpene lactone, induced apoptosis via ROS-mediated ER stress and JNK pathway in human U2OS cells PMCID:    Pubmed No.:27133064 Interval exercise training increases LIF expression and prevents myocardial infarction-induced skeletal muscle atrophy in rats PMCID:    Pubmed No.:29223542 YAP signaling in gastric cancer-derived mesenchymal stem cells is critical for its promoting role in cancer progression PMCID:    Pubmed No.:28848999 FV‐429 induces apoptosis and inhibits glycolysis by inhibiting Akt‐mediated phosphorylation of hexokinase II in MDA‐MB‐231 cells PMCID:    Pubmed No.:26258875 MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A PMCID:    Pubmed No.:28123563 Resveratrol improves human umbilical cord-derived mesenchymal stem cells repair for cisplatin-induced acute kidney injury PMCID:    Pubmed No.:30237401 miR-4293 upregulates lncRNA WFDC21P by suppressing mRNA-decapping enzyme 2 to promote lung carcinoma proliferation PMCID:    Pubmed No.:34301920 Potent effects of dioscin against hepatocellular carcinoma through regulating TP53‐induced glycolysis and apoptosis regulator (TIGAR)‐mediated apoptosis, autophagy, and DNA damage PMCID:    Pubmed No.:30710454 Luteolin ameliorates rat myocardial ischaemia–reperfusion injury through activation of peroxiredoxin II PMCID:    Pubmed No.:29782637 A Protein from Dioscorea polystachya (Chinese Yam) Improves Hydrocortisone-Induced Testicular Dysfunction by Alleviating Leydig Cell Injury via Upregulation of the Nrf2 Pathway PMCID:    Pubmed No.:34887997 The Roles of FGF21 and ALCAT1 in Aerobic Exercise-Induced Cardioprotection of Postmyocardial Infarction Mice PMCID:    Pubmed No.:34777697 Differential toxicities of triptolide to immortalized podocytes and the podocytes in vivo PMCID:    Pubmed No.:30551497 Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice PMCID:    Pubmed No.:29725084 Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice PMCID:    Pubmed No.:34084135 Pyridostigmine alleviates cardiac dysfunction via improving mitochondrial cristae shape in a mouse model of metabolic syndrome PMCID:    Pubmed No.:30633969 Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways PMCID:    Pubmed No.:32573644 A novel drug-free strategy of nano-pulse stimulation sequence (NPSS) in oral cancer therapy: In vitro and in vivo study PMCID:    Pubmed No.:29719274 Reversal Effects of Bound Polyphenol from Foxtail Millet Bran on Multidrug Resistance in Human HCT-8/Fu Colorectal Cancer Cell PMCID:    Pubmed No.:29730933 Kaempferol Reverses Aerobic Glycolysis via miR-339-5p-Mediated PKM Alternative Splicing in Colon Cancer Cells PMCID:    Pubmed No.:33663206 The RhoA/ROCK pathway mediates high glucose-induced cardiomyocyte apoptosis via oxidative stress, JNK, and p38MAPK pathways PMCID:    Pubmed No.:29745021 The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling PMCID:    Pubmed No.:31884423 HucMSC exosome-delivered 14-3-3ζ alleviates ultraviolet radiation-induced photodamage via SIRT1 pathway modulation PMCID:    Pubmed No.:33882455 Toosendanin Shows Potent Efficacy Against Human Ovarian Cancer through Caspase-Dependent Mitochondrial Apoptotic Pathway PMCID:    Pubmed No.:34521317 Mineralocorticoid receptor deficiency improves the therapeutic effects of mesenchymal stem cells for myocardial infarction via enhanced cell survival PMCID:    Pubmed No.:30549184 A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway PMCID:    Pubmed No.:30153443 The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway PMCID:    Pubmed No.:34425100 Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl-2 Associated X Protein (Bax) expression PMCID:    Pubmed No.:30775800 Long noncoding RNA LINC00961 inhibits cell proliferation and induces cell apoptosis in human non–small cell lung cancer PMCID:    Pubmed No.:30010215 Diterpene Ginkgolides Meglumine Injection inhibits apoptosis induced by optic nerve crush injury via modulating MAPKs signaling pathways in retinal ganglion cells PMCID:    Pubmed No.:34181957 Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling PMCID:    Pubmed No.:32848779 Protective effects of Salidroside on cardiac function in mice with myocardial infarction PMCID:    Pubmed No.:31792327 Profiles of messenger RNAs and MicroRNAs in hypoxia-induced hepatic stellate cells PMCID:    Pubmed No.:34734003 LncRNA-GAS5 promotes spinal cord repair and the inhibition of neuronal apoptosis via the transplantation of 3D printed scaffold loaded with induced pluripotent stem cell-derived neural stem cells PMCID:    Pubmed No.:34350246 The novel GLP-1/GIP dual agonist DA3-CH is more effective than liraglutide in reducing endoplasmic reticulum stress in diabetic rats with cerebral ischemia-reperfusion injury PMCID:    Pubmed No.:33500109 Ursolic acid induces apoptosis and anoikis in colorectal carcinoma RKO cells PMCID:    Pubmed No.:33549076 Anticancer effects of Poncirus fructus on hepatocellular carcinoma through regulation of apoptosis, migration, and invasion PMCID:    Pubmed No.:33125135 LncRNA SNHG6 Inhibits Apoptosis by Regulating EZH2 Expression via the Sponging of MiR-101-3p in Esophageal Squamous-Cell Carcinoma PMCID:    Pubmed No.:33192074 Echinocystic acid provides a neuroprotective effect via the PI3K/AKT pathway in intracerebral haemorrhage mice PMCID:    Pubmed No.:32055597 Rosmarinic acid elicits neuroprotection in ischemic stroke via Nrf2 and heme oxygenase 1 signaling PMCID:    Pubmed No.:30323140 Mitochondrial targeting of TR3 is involved in TPA induced apoptosis in breast cancer cells PMCID:    Pubmed No.:30641217 Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model PMCID:    Pubmed No.:30017231 Effect of Heat Treatment on the Anticancer Activity of Houttuynia cordata Thunb Aerial Stem Extract in Human Gastric Cancer SGC-7901 Cells PMCID:    Pubmed No.:32180441 Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen‑activated protein kinase signaling pathway PMCID:    Pubmed No.:30655881 -Hederin Arrests Cell Cycle at G2/M Checkpoint and Promotes Mitochondrial Apoptosis by Blocking Nuclear Factor-B Signaling in Colon Cancer Cells PMCID:    Pubmed No.:30363706 The novel GLP-1/GIP dual receptor agonist DA3-CH is neuroprotective in the pilocarpine-induced epileptogenesis rat model PMCID:    Pubmed No.:31121474 Post-treatment with the GLP-1 analogue liraglutide alleviate chronic inflammation and mitochondrial stress induced by Status epilepticus PMCID:    Pubmed No.:29549796 Semaglutide-mediated protection against Aβ correlated with enhancement of autophagy and inhibition of apotosis PMCID:    Pubmed No.:33222922 Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells PMCID:    Pubmed No.:32424110 Vildagliptin, a DPP4 inhibitor, alleviates diabetes‑associated cognitive deficits by decreasing the levels of apoptosis‑related proteins in the rat hippocampus PMCID:    Pubmed No.:29805536 Ethanol Extract of Hizikia fusiforme Induces Apoptosis in B16F10 Mouse Melanoma Cells through ROS-Dependent Inhibition of the PI3K/Akt Signaling Pathway PMCID:    Pubmed No.:32458633 FOXO3 Inhibits Human Gastric Adenocarcinoma (AGS) Cell Growth by Promoting Autophagy in an Acidic Microenvironment PMCID:    Pubmed No.:30138933 FOXO3 Inhibits Human Gastric Adenocarcinoma (AGS) Cell Growth by Promoting Autophagy in an Acidic Microenvironment PMCID:    Pubmed No.:30138933 Neuroprotective effect of Ginsenoside Re against neurotoxin‑induced Parkinson's disease models via induction of Nrf2 PMCID:    Pubmed No.:35543148 IL-27 regulates autophagy in rheumatoid arthritis fibroblast-like synoviocytes via STAT3 signaling PMCID:    Pubmed No.:35820245 Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells PMCID:    Pubmed No.:36144207 Cardioprotection Attributed to Aerobic Exercise-Mediated Inhibition of ALCAT1 and Oxidative Stress-Induced Apoptosis in MI Rats PMCID:    Pubmed No.:36140351 Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia–Reperfusion Injury in Mice PMCID:    Pubmed No.:36297399