Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth PMCID:    Pubmed No.:25695606 ART-induced biophysical and biochemical alterations of Jurkat cell membrane PMCID:    Pubmed No.:20888245 TRAIL and doxorubicin combination enhances anti-glioblastoma effect based on passive tumor targeting of liposomes PMCID:    Pubmed No.:21609741 Exogenous melatonin modulates apoptosis in the mouse brain induced by high-LET carbon ion irradiation PMCID:    Pubmed No.:21812816 MicroRNA-195 Promotes Apoptosis in Mouse Podocytes via Enhanced Caspase Activity Driven by BCL2 Insufficiency PMCID:    Pubmed No.:22123611 The role of radix hedysari polysaccharide on the human umbilical vein endothelial cells induced by high glucose PMCID:    Pubmed No.:22385890 MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer PMCID:    Pubmed No.:22388101 In vitro Anti-Angiogenesis Effects and Active Constituents of the Saponin Fraction From Gleditsia sinensis PMCID:    Pubmed No.:22505594 Combination of TRAIL and actinomycin D liposomes enhances antitumor effect in non-small cell lung cancer PMCID:    Pubmed No.:22619505 Induction and Mechanism of Apoptosis by Hydroxycamptothecin in Human Tenon's Capsule Fibroblasts PMCID:    Pubmed No.:22661476 Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer PMCID:    Pubmed No.:22687635 Down regulation of differentiated embryonic chondrocytes 1 (DEC1) is involved in 8-methoxypsoralen-induced apoptosis in HepG2 cells PMCID:    Pubmed No.:22796345 NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK- dependent mitochondrial pathway PMCID:    Pubmed No.:22824464 Phycocyanin may suppress d-galactose-induced human lens epithelial cell apoptosis through mitochondrial and unfolded protein response pathways PMCID:    Pubmed No.:23036742 Lentivirus-mediated Sirt1 shRNA and resveratrol independently induce porcine preadipocyte apoptosis by canonical apoptotic pathway PMCID:    Pubmed No.:23065251 T63, a New 4-Arylidene Curcumin Analogue induces cell cycle arrest and apoptosis through activation of Reactive Oxygen Species-FOXO3a pathway in lung cancer cells PMCID:    Pubmed No.:23085518 Effects of Tetramethylpyrazine on Neuronal Apoptosis in the Superficial Dorsal Horn in a Rat Model of Neuropathic Pain PMCID:    Pubmed No.:23227794 Osteopontin Splice Variants Differentially Exert Clinicopathological Features and Biological Functions in Gastric Cancer PMCID:    Pubmed No.:23289017 miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation PMCID:    Pubmed No.:23333058 Acetylcholine Attenuates Hypoxia/ Reoxygenation-Induced Mitochondrial and Cytosolic ROS Formation in H9c2 Cells via M2 Acetylcholine Receptor PMCID:    Pubmed No.:23407103 2-methoxyjuglone induces apoptosis in HepG2 human hepatocellular carcinoma cells and exhibits in vivo antitumor activity in a H22 mouse hepatocellular carcinoma model. PMCID:    Pubmed No.:23597099 The anti-apoptotic and neuro-protective effects of human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) on acute optic nerve injury is transient PMCID:    Pubmed No.:23933426 Effects of Nicorandil in Neuroprotective Activation of PI3K/AKT Pathways in a Cellular Model of Alzheimer's Disease PMCID:    Pubmed No.:24008440 ONTD induces apoptosis of human hepatoma Bel-7402 cells via a MAPK-dependent mitochondrial pathway and the depletion of intracellular glutathione PMCID:    Pubmed No.:24036456 IGF-1 gene-modified muscle-derived stem cells are resistant to oxidative stress via enhanced activation of IGF-1R/PI3K/AKT signaling and secretion of VEGF PMCID:    Pubmed No.:24126783 (S)-ZJM-289 Preconditioning Induces a Late Phase Protection Against Nervous Injury Induced by Transient Cerebral Ischemia and Oxygen-Glucose Deprivation PMCID:    Pubmed No.:24277159 Decoy Oligonucleotide Rescues IGF1R Expression from MicroRNA-223 Suppression PMCID:    Pubmed No.:24324762 Fluoride‐induced apoptosis and expressions of caspase proteins in the kidney of carp (Cyprinus carpio) PMCID:    Pubmed No.:24459041 Norisoboldine induces apoptosis of fibroblast-like synoviocytes from adjuvant-induced arthritis rats PMCID:    Pubmed No.:24613208 ZnO nanoparticle-induced oxidative stress triggers apoptosis by activating JNK signaling pathway in cultured primary astrocytes PMCID:    Pubmed No.:24624962 Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways PMCID:    Pubmed No.:24686182 Ribonuclease inhibitor up-regulation inhibits the growth and induces apoptosis in murine melanoma cells through repression of angiogenin and ILK/PI3K/AKT signaling pathway. PMCID:    Pubmed No.:24769129 Hydrogen Sulfide Attenuates the Recruitment of CD11b+ Gr-1+ Myeloid Cells and Regulates Bax/Bcl-2 Signaling in Myocardial Ischemia Injury PMCID:    Pubmed No.:24758901 Hyperbaric Oxygen Suppresses Hypoxic-Ischemic Brain Damage in Newborn Rats PMCID:    Pubmed No.:24762865 Mark4 promotes adipogenesis and triggers apoptosis in 3T3-L1 adipocytes by activating JNK1 and inhibiting p38MAPK pathways. PMCID:    Pubmed No.:24989893 Chronic sleep restriction induces changes in the mandibular condylar cartilage of rats: roles of Akt, Bad and Caspase-3 (Application: IHC) PMCID:    Pubmed No.:25356113 A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome PMCID:    Pubmed No.:25270903 Effect of vitamin C administration on hydrogen peroxide‑induced cytotoxicity in periodontal ligament cells PMCID:    Pubmed No.:25333298 Suppression of epithelial-mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells. PMCID:    Pubmed No.:25501598 Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice PMCID:    Pubmed No.:26064905 Ameliorating the Effect of Astragaloside IV on Learning and Memory Deficit after Chronic Cerebral Hypoperfusion in Rats PMCID:    Pubmed No.:25625683 Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells. PMCID:    Pubmed No.:26204324 Phenethyl isothiocyanate enhances adriamycin‑induced apoptosis in osteosarcoma cells PMCID:    Pubmed No.:26252906 Gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway PMCID:    Pubmed No.:26318432 Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells Protect against Experimental Colitis via Attenuating Colon Inflammation, Oxidative Stress and Apoptosis. PMCID:    Pubmed No.:26469068 Racemic oleracein E increases the survival rate and attenuates memory impairment in D-galactose/NaNO 2-induced senescent mice PMCID:    Pubmed No.:27064004 PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells PMCID:    Pubmed No.:26860588 Persistent mitoKATP Activation Is Involved in the Isoflurane-induced Cytotoxicity PMCID:    Pubmed No.:26803495 ZFX Facilitates Cell Proliferation and Imatinib Resistance in Chronic Myeloid Leukemia Cells PMCID:    Pubmed No.:26912059 YiQiFuMai powder injection attenuates ischemia/reperfusion-induced myocardial apoptosis through AMPK activation PMCID:    Pubmed No.:27072567 Chronic sleep restriction induces changes in the mandibular condylar cartilage of rats: roles of Akt, Bad and Caspase-3 (Application: IHC) PMCID:    Pubmed No.:25356113 A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome PMCID:    Pubmed No.:25270903 Effect of vitamin C administration on hydrogen peroxide‑induced cytotoxicity in periodontal ligament cells PMCID:    Pubmed No.:25333298 Suppression of epithelial-mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells. PMCID:    Pubmed No.:25501598 IGF-1 gene-modified muscle-derived stem cells are resistant to oxidative stress via enhanced activation of IGF-1R/PI3K/AKT signaling and secretion of VEGF PMCID:    Pubmed No.:24126783 (S)-ZJM-289 Preconditioning Induces a Late Phase Protection Against Nervous Injury Induced by Transient Cerebral Ischemia and Oxygen-Glucose Deprivation PMCID:    Pubmed No.:24277159 Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells Protect against Experimental Colitis via Attenuating Colon Inflammation, Oxidative Stress and Apoptosis. PMCID:    Pubmed No.:26469068 Racemic oleracein E increases the survival rate and attenuates memory impairment in D-galactose/NaNO 2-induced senescent mice PMCID:    Pubmed No.:27064004 PFR peptide, one of the antimicrobial peptides identified from the derivatives of lactoferrin, induces necrosis in leukemia cells PMCID:    Pubmed No.:26860588 Persistent mitoKATP Activation Is Involved in the Isoflurane-induced Cytotoxicity PMCID:    Pubmed No.:26803495 ZFX Facilitates Cell Proliferation and Imatinib Resistance in Chronic Myeloid Leukemia Cells PMCID:    Pubmed No.:26912059 YiQiFuMai powder injection attenuates ischemia/reperfusion-induced myocardial apoptosis through AMPK activation PMCID:    Pubmed No.:27072567 Ribonuclease inhibitor up-regulation inhibits the growth and induces apoptosis in murine melanoma cells through repression of angiogenin and ILK/PI3K/AKT signaling pathway. PMCID:    Pubmed No.:24769129 Hydrogen Sulfide Attenuates the Recruitment of CD11b+ Gr-1+ Myeloid Cells and Regulates Bax/Bcl-2 Signaling in Myocardial Ischemia Injury PMCID:    Pubmed No.:24758901 Hyperbaric Oxygen Suppresses Hypoxic-Ischemic Brain Damage in Newborn Rats PMCID:    Pubmed No.:24762865 Decoy Oligonucleotide Rescues IGF1R Expression from MicroRNA-223 Suppression PMCID:    Pubmed No.:24324762 Fluoride‐induced apoptosis and expressions of caspase proteins in the kidney of carp (Cyprinus carpio) PMCID:    Pubmed No.:24459041 Norisoboldine induces apoptosis of fibroblast-like synoviocytes from adjuvant-induced arthritis rats PMCID:    Pubmed No.:24613208 ZnO nanoparticle-induced oxidative stress triggers apoptosis by activating JNK signaling pathway in cultured primary astrocytes PMCID:    Pubmed No.:24624962 Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways PMCID:    Pubmed No.:24686182 Racemic oleracein E increases the survival rate and attenuates memory impairment in D-galactose/NaNO2-induced senescent mice PMCID:    Pubmed No.:27064004 Phenolic alkaloid oleracein E attenuates oxidative stress and neurotoxicity in AlCl3-treated mice PMCID:    Pubmed No.:29054451 ATRQβ-001 vaccine prevents atherosclerosis in apolipoprotein E-null mice PMCID:    Pubmed No.:26771341 Neuroprotective effects of hydrogen sulfide on sodium azide-induced oxidative stress in PC12 cells PMCID:    Pubmed No.:29115393 Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice PMCID:    Pubmed No.:26064905 Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway PMCID:    Pubmed No.:28734031 The stress-response molecule NR4A1 resists ROS-induced pancreatic β-cells apoptosis via WT1 PMCID:    Pubmed No.:28342843 Synthesis, antiproliferative and apoptosis-inducing effects of novel asiatic acid derivatives containing α-aminophosphonates PMCID:    Pubmed No.:24262379 Curcumin-cyclodextrin complexes enhanced the anti-cancer effects of curcumin PMCID:    Pubmed No.:27716533 Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells PMCID:    Pubmed No.:26204324 Associations between autophagy, the ubiquitin-proteasome system and endoplasmic reticulum stress in hypoxia-deoxygenation or ischemia-reperfusion PMCID:    Pubmed No.:27568838 Clostridium butyricum attenuates cerebral ischemia/reperfusion injury in diabetic mice via modulation of gut microbiota PMCID:    Pubmed No.:27037183 Study on the mitochondrial apoptosis pathways of small cell lung cancer H446 cells induced by Trichinella spiralis muscle larvae ESPs PMCID:    Pubmed No.:28073393 Phenethyl isothiocyanate enhances adriamycin‑induced apoptosis in osteosarcoma cells PMCID:    Pubmed No.:26252906 scAAV9-VEGF prolongs the survival of transgenic ALS mice by promoting activation of M2 microglia and the PI3K/Akt pathway PMCID:    Pubmed No.:27392886 TRAF2 is a Valuable Prognostic Biomarker in Patients with Prostate Cancer PMCID:    Pubmed No.:28855498 Downregulation of Foxc2 enhances apoptosis induced by 5-fluorouracil through activation of MAPK and AKT pathways in colorectal cancer PMCID:    Pubmed No.:26893778 AAV9-IGF1 protects TDP-25 cells from apoptosis and oxidative stress partly via up-regulating the expression of VEGF in vitro PMCID:    Pubmed No.:28108397 Tan IIA inhibits H1299 cell viability through the MDM4‑IAP3 signaling pathway PMCID:    Pubmed No.:29207086 Targeting survivin using a combination of miR‑494 and survivin shRNA has synergistic effects on the suppression of prostate cancer growth PMCID:    Pubmed No.:26718651 LFG-500, a newly synthesized flavonoid, induces apoptosis in human ovarian carcinoma SKOV3 cells with involvement of the reactive oxygen species-mitochondria pathway PMCID:    Pubmed No.:28587346 Lentivirus-induced knockdown of LRP1 induces osteoarthritic-like effects and increases susceptibility to apoptosis in chondrocytes via the nuclear factor-κB pathway PMCID:    Pubmed No.:26170918 Methyl methanesulfonate induces necroptosis in human lung adenoma A549 cells through the PIG-3-reactive oxygen species pathway PMCID:    Pubmed No.:26472723 ING4 expressing oncolytic vaccinia virus promotes anti-tumor efficiency and synergizes with gemcitabine in pancreatic cancer PMCID:    Pubmed No.:29137298 Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice PMCID:    Pubmed No.:34084135 AIM2 promotes non‐small‐cell lung cancer cell growth through inflammasome‐dependent pathway PMCID:    Pubmed No.:30953357 Hydrogen sulfide protects against cell damage through modulation of PI3K/Akt/Nrf2 signaling PMCID:    Pubmed No.:31654751 The PI3K inhibitor buparlisib suppresses osteoclast formation and tumour cell growth in bone metastasis of lung cancer, as evidenced by multimodality molecular imaging PMCID:    Pubmed No.:30896825 Myeloid NEMO deficiency promotes tumor immunosuppression partly via MCP1-CCR2 axis PMCID:    Pubmed No.:33428904 Systemic administration of scAAV9-IGF1 extends survival in SOD1G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway PMCID:    Pubmed No.:29499331 Chronic restraint stress exacerbates neurological deficits and disrupts the remodeling of the neurovascular unit in a mouse intracerebral hemorrhage model PMCID:    Pubmed No.:31591949 Salubrinal offers neuroprotection through suppressing endoplasmic reticulum stress, autophagy and apoptosis in a mouse traumatic brain injury model PMCID:    Pubmed No.:30851432 Delayed cognitive deficits can be alleviated by calcium antagonist nimodipine by downregulation of apoptosis following whole brain radiotherapy PMCID:    Pubmed No.:30013647 Downregulation of Frizzled-7 induces the apoptosis of hepatocellular carcinoma cells through inhibition of NF-κB PMCID:    Pubmed No.:29731900 Restraint Stress Delays the Recovery of Neurological Impairments and Exacerbates Brain Damages through Activating Endoplasmic Reticulum Stress-mediated Neurodegeneration/Autophagy/Apopotosis post Moderate Traumatic Brain Injury PMCID:    Pubmed No.:35001355 Mechanism of Shiliu Buxue Syrup for anemia using integrated metabolomics and network pharmacology PMCID:    Pubmed No.:35690102 Brain-specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury PMCID:    Pubmed No.:36271611 Nitro-oleic acid ameliorates erectile dysfunction in a streptozotocin-induced rat model of diabetes by inhibiting oxidative stress and apoptosis and activating the NO/cGMP pathway PMCID:    Pubmed No.:37695220 Pramipexole has a neuroprotective effect in spinal cord injury and upregulates D2 receptor expression in the injured spinal cord tissue in rats PMCID:    Pubmed No.:37719118