Sox9 (Q175) polyclonal antibody 
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Product Name :
Sox9 (Q175) polyclonal antibody Background :
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
SOX-9 (Q175) polyclonal antibody detects endogenous levels of SOX-9 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 150-200 of Human Sox9. Conjugate :
Unconjugated Modification :
Unmodification
Sox9 (Q175) polyclonal antibody Background :
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
SOX-9 (Q175) polyclonal antibody detects endogenous levels of SOX-9 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 150-200 of Human Sox9. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of Sox9 (Q175) polyclonal antibody at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:Panc1 whole cell lysate(40ug) -
Immunohistochemistry (IHC) analyzes of Sox9 (Q175) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Association of hsa-miR‑145 overexpression in human testicular cells with male infertility
PMCID: Pubmed No.:25633044
Abrasion arthroplasty increases mesenchymal stem cell content of postoperative joint effusions
PMCID: Pubmed No.:26364138
Fuyuan Decoction Enhances SOX9 and COL2A1 Expression and Smad2/3 Phosphorylation in IL-1β-Activated Chondrocytes
PMCID: Pubmed No.:26770254
Altered function in cartilage derived mesenchymal stem cell leads to OA-related cartilage erosion
PMCID: Pubmed No.:27158337
Abrasion arthroplasty increases mesenchymal stem cell content of postoperative joint effusions
PMCID: Pubmed No.:26364138
Fuyuan Decoction Enhances SOX9 and COL2A1 Expression and Smad2/3 Phosphorylation in IL-1β-Activated Chondrocytes
PMCID: Pubmed No.:26770254
Downregulation of prostaglandin E2 is involved in hindgut mucosal damage in lactating goats fed a high‐concentrate diet
PMCID: Pubmed No.:26593381
Abrasion arthroplasty increases mesenchymal stem cell content of postoperative joint effusions
PMCID: Pubmed No.:26364138
Dental and periodontal phenotypes of Dlx2 overexpression in mice
PMCID: Pubmed No.:28447749
Association of hsa-miR‑145 overexpression in human testicular cells with male infertility
PMCID: Pubmed No.:25633044
Fuyuan Decoction Enhances SOX9 and COL2A1 Expression and Smad2/3 Phosphorylation in IL-1β-Activated Chondrocytes
PMCID: Pubmed No.:26770254
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress
PMCID: Pubmed No.:30829051
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.