IFNB1 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
IFNB1 polyclonal antibody Background :
The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
IFNB1 polyclonal antibody detects endogenous levels of IFNB1 protein. Immunogen :
A synthetic peptide corresponding to residues in Human IFNB1. Conjugate :
Unconjugated Modification :
Unmodification
IFNB1 polyclonal antibody Background :
The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
IFNB1 polyclonal antibody detects endogenous levels of IFNB1 protein. Immunogen :
A synthetic peptide corresponding to residues in Human IFNB1. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of IFNB1 polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat liver tissue lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.