HABP2 polyclonal antibody 
Datasheet
COA
MSDS
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Product Name :
HABP2 polyclonal antibody Background :
The hyaluronan-binding protein 2 (HABP2), also designated plasma hyaluronan-binding protein (PHBP) or factor VII-activating protease, belongs to the peptidase S1 family and contains three EGF-like domains, one kringle domain and one peptidase S1 domain. HABP2 is a heterodimer that contains a heavy chain of 50 kDa and a light chain of 27 kDa, which are linked by a disulfide bond. HABP2 is ubiquitously expressed and acts as a serine protease with fibrinogen and fibronectin being the major substrates. HABP2 has been shown to cleave the alpha-chain at multiple sites and the beta-chain between lysine53 and lysine54, but not the gamma-chain of fibrinogen. Overexpression of HABP2 has been shown to occur in lung adenocarcinomas and may be a useful biomarker for that type of cancer. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
HABP2 polyclonal antibody detects endogenous levels of HABP2 protein. Immunogen :
A synthetic peptide corresponding to residues in Human HABP2 Conjugate :
Unconjugated Modification :
Unmodification
HABP2 polyclonal antibody Background :
The hyaluronan-binding protein 2 (HABP2), also designated plasma hyaluronan-binding protein (PHBP) or factor VII-activating protease, belongs to the peptidase S1 family and contains three EGF-like domains, one kringle domain and one peptidase S1 domain. HABP2 is a heterodimer that contains a heavy chain of 50 kDa and a light chain of 27 kDa, which are linked by a disulfide bond. HABP2 is ubiquitously expressed and acts as a serine protease with fibrinogen and fibronectin being the major substrates. HABP2 has been shown to cleave the alpha-chain at multiple sites and the beta-chain between lysine53 and lysine54, but not the gamma-chain of fibrinogen. Overexpression of HABP2 has been shown to occur in lung adenocarcinomas and may be a useful biomarker for that type of cancer. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
HABP2 polyclonal antibody detects endogenous levels of HABP2 protein. Immunogen :
A synthetic peptide corresponding to residues in Human HABP2 Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of HABP2 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:PC12 whole cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.