NLGN3 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
NLGN3 polyclonal antibody Background :
Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain . Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3 . Neuroligins are expressed in excitatory neuronal synaptic clefts . Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins . Neuroexin 1∫ binds to the EF-hand domain of Neuroligin 1 and requires calcium ion . Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses . Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
NLGN3 polyclonal antibody detects endogenous levels of NLGN3 protein. Immunogen :
A synthetic peptide corresponding to residues in Human NLGN3 Conjugate :
Unconjugated Modification :
Unmodification
NLGN3 polyclonal antibody Background :
Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain . Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3 . Neuroligins are expressed in excitatory neuronal synaptic clefts . Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins . Neuroexin 1∫ binds to the EF-hand domain of Neuroligin 1 and requires calcium ion . Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses . Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
NLGN3 polyclonal antibody detects endogenous levels of NLGN3 protein. Immunogen :
A synthetic peptide corresponding to residues in Human NLGN3 Conjugate :
Unconjugated Modification :
Unmodification
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Western blot (WB) analysis of NLGN3 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.