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GRM1 polyclonal antibody BS60765
  • Western blot (WB) analysis of GRM1 polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate
Product NameGRM1 polyclonal antibody
Catalog No.BS60765
Swiss-ProtQ13255
Host Rabbit
ReactivityHuman
ApplicationsWB
Application_allWB: 1:500~1:1000
BiowMW~ 132 kDa
Alternative NameMetabotropic glutamate receptor 1; mGluR1; GRM1; GPRC1A; MGLUR1
Purification&PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ConjugateUnconjugated
ModificationUnmodification
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Size Price
50ul $158
100ul $275
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Product Name :
GRM1 polyclonal antibody
Background :
The mGluR proteins (metabotropic glutamate receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-1, which can form a homodimer acts as a receptor for glutamate. It may also be involved in glutamate activity in the CNS.
Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :
GRM1 polyclonal antibody detects endogenous levels of GRM1 protein.
Immunogen :
A synthetic peptide corresponding to residues in Human GRM1
Conjugate :
Unconjugated
Modification :
Unmodification
  • Western blot (WB) analysis of GRM1 polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
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