Product Name :
ARSD polyclonal antibody Background :
Arylsulfatase D, also known as ARSD, is a 593 amino acid protein that localizes to the lysosome and belongs to the sulfatase family of bone and cartilage matrix proteins. Existing as three alternatively spliced isoforms which are expressed in liver, pancreas, kidney, heart, brain, lung and placenta, Arylsulfatase D uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ARSD polyclonal antibody detects endogenous levels of ARSD protein. Immunogen :
A synthetic peptide corresponding to residues in Human ARSD. Conjugate :
Unconjugated Modification :
Unmodification
ARSD polyclonal antibody Background :
Arylsulfatase D, also known as ARSD, is a 593 amino acid protein that localizes to the lysosome and belongs to the sulfatase family of bone and cartilage matrix proteins. Existing as three alternatively spliced isoforms which are expressed in liver, pancreas, kidney, heart, brain, lung and placenta, Arylsulfatase D uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ARSD polyclonal antibody detects endogenous levels of ARSD protein. Immunogen :
A synthetic peptide corresponding to residues in Human ARSD. Conjugate :
Unconjugated Modification :
Unmodification
-
Western blot (WB) analysis of ARSD polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:sp2/0 whole cell lysate
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.