Product Name :
Integrin β2 polyclonal antibody Background :
The small inducible genes (SIG) family encodes proteins that are involved in overlapping processes of inflammation, immune response, wound repair and coagulation. The SIG family contains two branches, designated CXC and CC, distinguished by whether or not the first two of four conserved cysteine residues are separated by an additional amino acid residue. The CXC SIGs map to human chromosome 4, including those encoding beta-thromboglobulin and platelet factor 4 (PF4), which are both expressed by megakaryocytes in a tissue-specific fashion and duplicated, there being a PF4 and a PF4alt gene, and a beta TG1 and beta TG2 gene. PPBPL1 (pro-platelet basic protein-like 1), also known as TGB2 (thromboglobulin, beta-2), belongs to the SIG family and is a CXC SIG protein, which contains four cysteine residues separated by a single amino acid residue. PPBPL1 is closely linked to other PPBPs, PF4s and several other CXC SIGs in a 700-kb Sfi1 fragment that localizes to chromosome 4q12-q13. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ITGB2 polyclonal antibody detects endogenous levels of ITGB2 protein. Immunogen :
A synthetic peptide corresponding to residues in Human ITGB2. Conjugate :
Unconjugated Modification :
Unmodification

• 
  Western blot (WB) analysis of ITGB2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate

Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

---

Price/Size :

USD 368/1mg/vial

---

---

Tips: 

For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).

---

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

---

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

---

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 

---

Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.

---