FADS1 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
FADS1 polyclonal antibody Background :
Members of the fatty acid desaturase (FADS) family, including FADS1, FADS2 and FADS3, regulate the desaturation of fatty acids by introducing double bonds between defined carbons of fatty acyl chains, thereby playing an essential role in the lipid metabolic pathway. Members of this family share N-terminal cytochrome b5-like domains, C-terminal multiple membrane-spanning desaturase regions and 3 histidine box motifs. It has been suggested that single nucleotide polymorphisms (SNPs) within the FADS gene cluster may be associated with diseases related to inflammation and immunity processes. FADS1, also known as Delta desaturase or D5D, is a 444 amino acid protein that is abundantly expressed in liver, brain, adrenal gland and heart. Localized to the endoplasmic reticulum where it exists as a multi-pass membrane protein, FADS1 catalyzes the biosynthesis of highly unsaturated fatty acids from linoleic acid and alpha-linolenic acid. Additionally, FADS1 functions to catalyze the desaturation of both dihomo-gamma-linoleic acid (DHGLA) and eicosatetraenoic acid (EA) to produce arachidonic acid (AA) and eicosapentaenoic acid (EPA), respectively. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
FADS1 polyclonal antibody detects endogenous levels of FADS1 protein. Immunogen :
Recombinant full length Human FADS1. Conjugate :
Unconjugated Modification :
Unmodification
FADS1 polyclonal antibody Background :
Members of the fatty acid desaturase (FADS) family, including FADS1, FADS2 and FADS3, regulate the desaturation of fatty acids by introducing double bonds between defined carbons of fatty acyl chains, thereby playing an essential role in the lipid metabolic pathway. Members of this family share N-terminal cytochrome b5-like domains, C-terminal multiple membrane-spanning desaturase regions and 3 histidine box motifs. It has been suggested that single nucleotide polymorphisms (SNPs) within the FADS gene cluster may be associated with diseases related to inflammation and immunity processes. FADS1, also known as Delta desaturase or D5D, is a 444 amino acid protein that is abundantly expressed in liver, brain, adrenal gland and heart. Localized to the endoplasmic reticulum where it exists as a multi-pass membrane protein, FADS1 catalyzes the biosynthesis of highly unsaturated fatty acids from linoleic acid and alpha-linolenic acid. Additionally, FADS1 functions to catalyze the desaturation of both dihomo-gamma-linoleic acid (DHGLA) and eicosatetraenoic acid (EA) to produce arachidonic acid (AA) and eicosapentaenoic acid (EPA), respectively. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
FADS1 polyclonal antibody detects endogenous levels of FADS1 protein. Immunogen :
Recombinant full length Human FADS1. Conjugate :
Unconjugated Modification :
Unmodification
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.