Product Name :
CFDP1 polyclonal antibody Background :
CFDP1 (Craniofacial development protein 1), also known as Bucentaur and CP27, is a 299 amino acid protein that is involved in embryogenesis and normal cell function. When treated with CFDP1 peptide, mouse molar teeth increase in size, whereas treating cells with antibodies against CFDP1 shows an increase in the number of apoptotic cells and gradual tooth disintegration. CFDP1 is highly expressed in developing mouse teeth and is expressed at lower levels in liver, lung and heart. The gene encoding CFDP1 maps to human chromsome 16, in a region that has been associated with inherited craniofacial diseases, such as fanconi anemia type A. There are two isoforms of CFDP1 that are produced as a result of alternative splicing events. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CFDP1 polyclonal antibody detects endogenous levels of CFDP1 protein. Immunogen :
Recombinant full length Human CFDP1. Conjugate :
Unconjugated Modification :
Unmodification
CFDP1 polyclonal antibody Background :
CFDP1 (Craniofacial development protein 1), also known as Bucentaur and CP27, is a 299 amino acid protein that is involved in embryogenesis and normal cell function. When treated with CFDP1 peptide, mouse molar teeth increase in size, whereas treating cells with antibodies against CFDP1 shows an increase in the number of apoptotic cells and gradual tooth disintegration. CFDP1 is highly expressed in developing mouse teeth and is expressed at lower levels in liver, lung and heart. The gene encoding CFDP1 maps to human chromsome 16, in a region that has been associated with inherited craniofacial diseases, such as fanconi anemia type A. There are two isoforms of CFDP1 that are produced as a result of alternative splicing events. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
CFDP1 polyclonal antibody detects endogenous levels of CFDP1 protein. Immunogen :
Recombinant full length Human CFDP1. Conjugate :
Unconjugated Modification :
Unmodification
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WesternBlot (WB) analysis of CFDP1 polyclonal antibody
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.