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CD1a polyclonal antibody BS90223
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD1a antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.
Product NameCD1a polyclonal antibody
Catalog No.BS90223
Swiss-ProtP06126(Human)
Host Rabbit
ReactivityHuman
ApplicationsWB IHC
Application_allWB:1:500 IHC:1:50-1:200
BiowMW37 kDa
Alternative NamehTa1 thymocyte antigen, CD1a, CD1A, CD 1a, CD1, CD1a, CD1A Antigen, CD1A antigen, a polypeptide, CD1a molecule, CD1A, cluster of differentiation 1 A, cortical thymocyte antigen CD1A, differentiation antigen CD1 alpha 3, epidermal dendritic cell marker CD1a, FCB 6, FCB6, HTA 1, HTA1, hTa1 thymocyte antigen, OTTHUMP00000018907, R 4, R4, T 6, T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6,
Purification&PurityProA affinity purified
ConjugateUnconjugated
ModificationUnmodification
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Size Price
50ul $258
100ul $398
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Product Name :
CD1a polyclonal antibody
Background :
The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with β-2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1.
Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage&Stability :
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity :
CD1a polyclonal antibody detects endogenous levels of CD1a protein.
Immunogen :
recombinant protein
Conjugate :
Unconjugated
Modification :
Unmodification
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD1a antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-CD1a antibody. Counter stained with hematoxylin.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.

Price/Size :

USD 368/1mg/vial



Tips: 

For phospho antibody, we provide phospho peptide(0.5mg) and non-phospho peptide(0.5mg).

Describe :

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.

Formula:

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.

Storage:

The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C. 


Note :

This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.
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