IL17RB polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
IL17RB polyclonal antibody Background :
Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. IL-17RB is a member of the cytokine receptor family and acts as a receptor for the proinflammatory cytokines IL-17B and IL-17E. It may play a role in hematopoietic cell differentiation and growth. IL-17RB expression is high in liver, colon, brain, kidney and testis. IL-17RB is detected in fibroblast-like synoviocytes of rheumatoid arthritis patients. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Specificity :
IL17RB polyclonal antibody detects endogenous levels of IL17RB protein. Immunogen :
Recombinant protein Conjugate :
Unconjugated Modification :
Unmodification
IL17RB polyclonal antibody Background :
Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. IL-17RB is a member of the cytokine receptor family and acts as a receptor for the proinflammatory cytokines IL-17B and IL-17E. It may play a role in hematopoietic cell differentiation and growth. IL-17RB expression is high in liver, colon, brain, kidney and testis. IL-17RB is detected in fibroblast-like synoviocytes of rheumatoid arthritis patients. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Specificity :
IL17RB polyclonal antibody detects endogenous levels of IL17RB protein. Immunogen :
Recombinant protein Conjugate :
Unconjugated Modification :
Unmodification
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Western blot analysis of IL17RB on different lysates using anti-IL17RB antibody at 1/1,000 dilution. Positive control： Lane1: Mouse liver tissue Lane2: Human kidney tissue Lane3: Rat kidney tissue Lane4: SiHa
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.