Na+ CP type IXα (R692) polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
Na+ CP type IXα (R692) polyclonal antibody Background :
Voltage-gated Na+ channels regulate the permeability of excitable cells to sodium ions. During the propagation of an action potential, Na+ channels allow an influx of sodium ions, which rapidly depolarize the cell. The sodium channel protein is comprised of one α subunit and two β subunits. The Na+ CP type I and Na+ CP type IIα subunits are expressed in adult brain. Na+ CP type IIIα is expressed in embryonic brain, but not in adult brain. Na+ CP type IIIβ is a 215 amino acid, single-pass type I membrane protein that modulates sodium channel gating kinetics and inactivates the channel opening more slowly than the Iβ subunit. It has an extracellular N-terminal domain, an N-terminal signal sequence, a single membrane-spanning region and a C-terminal cytoplasmic region. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Na+ CP type IXα (R692) polyclonal antibody detects endogenous levels of Na+ CP type Ixα protein. Immunogen :
Synthetic peptide, corresponding to amino acids 660-718 of Human Na+ CP type IXα. Conjugate :
Unconjugated Modification :
Unmodification
Na+ CP type IXα (R692) polyclonal antibody Background :
Voltage-gated Na+ channels regulate the permeability of excitable cells to sodium ions. During the propagation of an action potential, Na+ channels allow an influx of sodium ions, which rapidly depolarize the cell. The sodium channel protein is comprised of one α subunit and two β subunits. The Na+ CP type I and Na+ CP type IIα subunits are expressed in adult brain. Na+ CP type IIIα is expressed in embryonic brain, but not in adult brain. Na+ CP type IIIβ is a 215 amino acid, single-pass type I membrane protein that modulates sodium channel gating kinetics and inactivates the channel opening more slowly than the Iβ subunit. It has an extracellular N-terminal domain, an N-terminal signal sequence, a single membrane-spanning region and a C-terminal cytoplasmic region. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Na+ CP type IXα (R692) polyclonal antibody detects endogenous levels of Na+ CP type Ixα protein. Immunogen :
Synthetic peptide, corresponding to amino acids 660-718 of Human Na+ CP type IXα. Conjugate :
Unconjugated Modification :
Unmodification
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Immunohistochemistry (IHC) analyzes of Na+ CP type IXα (R692) pAb in paraffin-embedded human lung cancer tissue.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.