GBDR1 (R126) polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
GBDR1 (R126) polyclonal antibody Background :
GBDR1 (glialblastoma cell differentiation-related protein 1), also known as UBAC1 (ubiquitin-associated domain-containing protein 1), KPC2 or UBADC1, is a 405 amino acid protein that localizes to the cytoplasm and contains one ubiquitin-like domain, one STI1 domain and two UBA domains. Expressed ubiquitously with highest expression in heart and skeletal muscle, GBDR1 functions as a non-catalytic subunit of the KPC E3 ubiquitin-protein ligase complex, of which RNF123 is the catalytic subunit. Existing as a critical component of the KPC complex, GBDR1 is essential for the ubiquitination and proteasome-mediated degradation of p27 during the G1 phase of the cell cycle. The gene encoding GBDR1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GBDR1 (R126) polyclonal antibody detects endogenous levels of GBDR1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 90-138 of Human GBDR1. Conjugate :
Unconjugated Modification :
Unmodification
GBDR1 (R126) polyclonal antibody Background :
GBDR1 (glialblastoma cell differentiation-related protein 1), also known as UBAC1 (ubiquitin-associated domain-containing protein 1), KPC2 or UBADC1, is a 405 amino acid protein that localizes to the cytoplasm and contains one ubiquitin-like domain, one STI1 domain and two UBA domains. Expressed ubiquitously with highest expression in heart and skeletal muscle, GBDR1 functions as a non-catalytic subunit of the KPC E3 ubiquitin-protein ligase complex, of which RNF123 is the catalytic subunit. Existing as a critical component of the KPC complex, GBDR1 is essential for the ubiquitination and proteasome-mediated degradation of p27 during the G1 phase of the cell cycle. The gene encoding GBDR1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
GBDR1 (R126) polyclonal antibody detects endogenous levels of GBDR1 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 90-138 of Human GBDR1. Conjugate :
Unconjugated Modification :
Unmodification
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Immunohistochemistry (IHC) analyzes of GBDR1 (R126) pAb in paraffin-embedded human breast cancer tissue.
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.