ZNF262 (H837) polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
ZNF262 (H837) polyclonal antibody Background :
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF262, also known as ZMYM4, is a 1,548 amino acid protein that contains 9 MYM-type zinc fingers. Four ZNF262 isoforms are expressed due to alternative splicing events, and are found in heart, skeletal muscle, kidney and liver. Upon DNA damage, ZNF262 may be phosphorylated by ATM or ATR. The mRNA encoding ZNF262 contains a CDIR motif (cell death inhibiting RNA) which binds to HNRPD/AUF1 and HSPB1/HSP27 and can inhibit FN-γ induced apoptosis. The gene encoding ZNF262 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ZNF262 (H837) polyclonal antibody detects endogenous levels of ZNF262 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 804-856 of Human ZNF262. Conjugate :
Unconjugated Modification :
Unmodification
ZNF262 (H837) polyclonal antibody Background :
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF262, also known as ZMYM4, is a 1,548 amino acid protein that contains 9 MYM-type zinc fingers. Four ZNF262 isoforms are expressed due to alternative splicing events, and are found in heart, skeletal muscle, kidney and liver. Upon DNA damage, ZNF262 may be phosphorylated by ATM or ATR. The mRNA encoding ZNF262 contains a CDIR motif (cell death inhibiting RNA) which binds to HNRPD/AUF1 and HSPB1/HSP27 and can inhibit FN-γ induced apoptosis. The gene encoding ZNF262 maps to chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome. Product :
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
ZNF262 (H837) polyclonal antibody detects endogenous levels of ZNF262 protein. Immunogen :
Synthetic peptide, corresponding to amino acids 804-856 of Human ZNF262. Conjugate :
Unconjugated Modification :
Unmodification
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.