CD133 monoclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
CD133 monoclonal antibody Background :
This gene encodes a pentaspan transmembrane glycoprotein.The protein localizes to membrane protrusions and is often expressed on adult stem cells,where it is thought to function in maintaining stem cell properties by suppressing differentiation.Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease.Expression of this gene is also associated with several types of cancer.This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner.Multiple transcript variants encoding different isoforms have been found for this gene. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This antibody detects endogenous levels of CD133 and does not cross-react with related proteins Immunogen :
Recombinant full length Human CD133. Conjugate :
Unconjugated Modification :
Unmodification
CD133 monoclonal antibody Background :
This gene encodes a pentaspan transmembrane glycoprotein.The protein localizes to membrane protrusions and is often expressed on adult stem cells,where it is thought to function in maintaining stem cell properties by suppressing differentiation.Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease.Expression of this gene is also associated with several types of cancer.This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner.Multiple transcript variants encoding different isoforms have been found for this gene. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This antibody detects endogenous levels of CD133 and does not cross-react with related proteins Immunogen :
Recombinant full length Human CD133. Conjugate :
Unconjugated Modification :
Unmodification
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Western blot detection of PROM1 antibody in CaCo2 cell lysate using PROM1 antibody (1:1000 diluted) .
Friend leukemia virus integration 1 is a predictor of poor prognosis of breast cancer and promotes metastasis and cancer stem cell properties of breast cancer cells
PMCID: Pubmed No.:29869379
Effects of NOTCH1 signaling inhibitor γ‑secretase inhibitor II on growth of cancer stem cells
PMCID: Pubmed No.:30405755
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.