Phospho-JAK2-Y1007/1008 polyclonal antibody 
Datasheet
COA
MSDS
SHIP
Product Name :
Phospho-JAK2-Y1007/1008 polyclonal antibody Background :
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Phosphorylated Antibodies Immunogen :
A synthetic phosphorylated peptide around Y1007 & Y1008 of human JAK2(NP_004963.1?). Conjugate :
Unconjugated Modification :
Phosphorylated
Phospho-JAK2-Y1007/1008 polyclonal antibody Background :
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. Product :
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
Phosphorylated Antibodies Immunogen :
A synthetic phosphorylated peptide around Y1007 & Y1008 of human JAK2(NP_004963.1?). Conjugate :
Unconjugated Modification :
Phosphorylated
-
Western blot (WB) analysis of Phospho-JAK2-Y1007/1008 polyclonal antibody at 1:1000 dilution Lane1:K562 treated with GM-CSF(100 ng/ml) at 37℃ for 15 minutes whole cell lysate(30ug) Lane2:K562 whole cell lysate(30ug) -
Immunohistochemistry of paraffin-embedded human liver cancer using Phospho-JAK2-Y1007/1008 antibody at dilution of 1:200 .Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. -
Immunohistochemistry of paraffin-embedded human liver cancer using Phospho-JAK2-Y1007/1008 antibody at dilution of 1:200 .Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. -
Immunohistochemistry of paraffin-embedded human liver cancer using Phospho-JAK2-Y1007/1008 antibody at dilution of 1:200 .Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Hydroxy-safflor yellow A inhibits neuroinflammation mediated by Aβ1–42 in BV-2 cells
PMCID: Pubmed No.:24412680
Hydroxy-safflor yellow A inhibits neuroinflammation mediated by Aβ1–42 in BV-2 cells
PMCID: Pubmed No.:24412680
Type II cGMP‑dependent protein kinase inhibits EGF‑induced JAK/STAT signaling in gastric cancer cells
PMCID: Pubmed No.:27357186
α-Hederin inhibits interleukin 6-induced epithelial-to-mesenchymal transition associated with disruption of JAK2/STAT3 signaling in colon cancer cells
PMCID: Pubmed No.:29477470
Ulinastatin protects rats from sepsis‐induced acute lung injury by suppressing the JAK‐STAT3 pathway
PMCID: Pubmed No.:30242880
Bioworld Biotech only provide peptides for our antibodies and do not provide additional peptide customization services.
Price/Size :
USD 368/1mg/vial
Tips:
For phospho antibody, we provide phospho peptide（0.5mg) and non-phospho peptide(0.5mg).Describe :
Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (WB) and Immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or IHC performed with the neutralized antibody.Formula:
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.The purity is >90%,tested by HPLC and MS.
Storage:
The freeze-dried powder is more stable. For short time at 2-8°C. For long term storage store at -20°C.
Note :
This product is for research use only (RUO only). Not for use in diagnostic or therapeutic procedures.