Recombinant Endostatin, Human 
Datasheet
COA
MSDS
SHIP
Recombinant :
Recombinant Endostatin, Human Source :
P. pastoris Molecular Weight :
~20.2kDa, observed by reducing SDS-PAGE. Purity :
Greater than 97% by SDS-PAGE Biological Activity :
Determined by Endothelial Cell Tube Formation. The cells treated with 10μg/ml Endostatin showed significant anti-angiogenesis effect. Physical Appearance :
Sterile Filtered White lyophilized (freeze-dried) powder. Formulation :
The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2. AA Sequence :
AH SHRDFQPVLH LVALNSPLSG GMRGIRGADF QCFQQARAVG LAGTFRAFLS SRLQDLYSIV RRADRAAVPI VNLKDELLFP SWEALFSGSE GPLKPGARIF SFDGKDVLRH PTWPQKSVWH GSDPNGRRLT ESYCETWRTE APSATGQASS LLGGRLLGQS AASCHHAYIV LCIENSFMTA SK Endotoxin :
Endotoxin level is less than 0.1 ng per μg (1EU/μg) of Endostatin. Reconstitution :
Reconstituted in ddH2O or PBS at 100 μg/ml. Storage :
The lyophilized Endostatin is stable for a few weeks at room temperature, but best stored at -20°C. For the first use, reconstitute in water, aliquot and store at -20°C to avoid multiple freeze-thaws. Usage :
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only. Description :
Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.
Recombinant Endostatin, Human Source :
P. pastoris Molecular Weight :
~20.2kDa, observed by reducing SDS-PAGE. Purity :
Greater than 97% by SDS-PAGE Biological Activity :
Determined by Endothelial Cell Tube Formation. The cells treated with 10μg/ml Endostatin showed significant anti-angiogenesis effect. Physical Appearance :
Sterile Filtered White lyophilized (freeze-dried) powder. Formulation :
The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2. AA Sequence :
AH SHRDFQPVLH LVALNSPLSG GMRGIRGADF QCFQQARAVG LAGTFRAFLS SRLQDLYSIV RRADRAAVPI VNLKDELLFP SWEALFSGSE GPLKPGARIF SFDGKDVLRH PTWPQKSVWH GSDPNGRRLT ESYCETWRTE APSATGQASS LLGGRLLGQS AASCHHAYIV LCIENSFMTA SK Endotoxin :
Endotoxin level is less than 0.1 ng per μg (1EU/μg) of Endostatin. Reconstitution :
Reconstituted in ddH2O or PBS at 100 μg/ml. Storage :
The lyophilized Endostatin is stable for a few weeks at room temperature, but best stored at -20°C. For the first use, reconstitute in water, aliquot and store at -20°C to avoid multiple freeze-thaws. Usage :
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only. Description :
Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues.
Blocking peptide available as BK0337-20μgP