APC (Q2829) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
APC (Q2829) Peptide Applications :
Blocking Background :
Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates ß-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. Alternative Name :
Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5; APC; DP2.5 Swiss-Prot :
P25054 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide APC (Q2829). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1017 APC (Q2829) pAb.
APC (Q2829) Peptide Applications :
Blocking Background :
Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates ß-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. Alternative Name :
Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5; APC; DP2.5 Swiss-Prot :
P25054 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide APC (Q2829). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1017 APC (Q2829) pAb.
Blocking peptide available as BS1017PP