TRAF4 (L302) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TRAF4 (L302) Peptide Applications :
Blocking Background :
The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystinerich extracellular domains. Members of this family include TNF-RI, TNF-RII and CD40. Ligands for these receptors can be small, secreted proteins, such as TNF, or type II integral membrane proteins, as is the case for the CD40 ligand, CD40L. While the signal transduction mechanism of the TNF receptor superfamily is poorly understood, activation of TNF-R or CD40 have been shown to induce the nuclear translocation of NFκB. Members of the TRAF (TNF receptor-associated factor) family have been implicated in this process. Four members have thus far been described and are designated TRAF1, TRAF2, TRAF3 (variously referred to as CRAF1, LAP1 or CD40bp) and TRAF4. TRAF4, originally termed CART1, is specifically expressed in breast carcinomas, and is localized to the nucleus in such tissues. Alternative Name :
CART 1; CART1; Malignant 62; MLN 62; MLN62; RING finger protein 83; RNF 83; RNF83; TRAF 4; Traf4; Swiss-Prot :
Q9BUZ4 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TRAF4 (L302). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9271 TRAF4 (L302) pAb.
TRAF4 (L302) Peptide Applications :
Blocking Background :
The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystinerich extracellular domains. Members of this family include TNF-RI, TNF-RII and CD40. Ligands for these receptors can be small, secreted proteins, such as TNF, or type II integral membrane proteins, as is the case for the CD40 ligand, CD40L. While the signal transduction mechanism of the TNF receptor superfamily is poorly understood, activation of TNF-R or CD40 have been shown to induce the nuclear translocation of NFκB. Members of the TRAF (TNF receptor-associated factor) family have been implicated in this process. Four members have thus far been described and are designated TRAF1, TRAF2, TRAF3 (variously referred to as CRAF1, LAP1 or CD40bp) and TRAF4. TRAF4, originally termed CART1, is specifically expressed in breast carcinomas, and is localized to the nucleus in such tissues. Alternative Name :
CART 1; CART1; Malignant 62; MLN 62; MLN62; RING finger protein 83; RNF 83; RNF83; TRAF 4; Traf4; Swiss-Prot :
Q9BUZ4 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TRAF4 (L302). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS9271 TRAF4 (L302) pAb.
Blocking peptide available as BS9271PP