Claudin-1 (R197) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Claudin-1 (R197) Peptide Applications :
Blocking Background :
The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tigh junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Alternative Name :
Claudin1; CLD1; ILVASC; SEMP1; Claudin 1; CLDN1; UNQ481/PRO944 Swiss-Prot :
O95832 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Claudin-1 (R197). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1063 Claudin-1 (R197) pAb.
Claudin-1 (R197) Peptide Applications :
Blocking Background :
The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tigh junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Alternative Name :
Claudin1; CLD1; ILVASC; SEMP1; Claudin 1; CLDN1; UNQ481/PRO944 Swiss-Prot :
O95832 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Claudin-1 (R197). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1063 Claudin-1 (R197) pAb.
Blocking peptide available as BS1063PP