Claudin-2 (S219) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Claudin-2 (S219) Peptide Applications :
Blocking Background :
Claudin-2, also known as CLDN2 or SP82, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily. Able to form homopolymers of heteropolymers with other claudin family members, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space. Overexpression of claudin-2 is associated with a variety of diseases, including lung cancer, colorectal cancer, gastrointestinal carcinomas and inflammatory bowel disease, further affirming the importance of claudin-2 in cell adhesion. Alternative Name :
Claudin2; Claudin 2; Claudin-2; CLDN2; PSEC0059; SP82; UNQ705/PRO1356 Swiss-Prot :
P57739 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Claudin-2 (S219). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1066 Claudin-2 (S219) pAb.
Claudin-2 (S219) Peptide Applications :
Blocking Background :
Claudin-2, also known as CLDN2 or SP82, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily. Able to form homopolymers of heteropolymers with other claudin family members, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space. Overexpression of claudin-2 is associated with a variety of diseases, including lung cancer, colorectal cancer, gastrointestinal carcinomas and inflammatory bowel disease, further affirming the importance of claudin-2 in cell adhesion. Alternative Name :
Claudin2; Claudin 2; Claudin-2; CLDN2; PSEC0059; SP82; UNQ705/PRO1356 Swiss-Prot :
P57739 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Claudin-2 (S219). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1066 Claudin-2 (S219) pAb.
Blocking peptide available as BS1066PP