CBP (V2427) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
CBP (V2427) Peptide Applications :
Blocking Background :
Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB, which is activated as a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. Alternative Name :
CREB-binding protein; CREBBP; CBP Swiss-Prot :
Q92793 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CBP (V2427). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1078 CBP (V2427) pAb.
CBP (V2427) Peptide Applications :
Blocking Background :
Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB, which is activated as a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. Alternative Name :
CREB-binding protein; CREBBP; CBP Swiss-Prot :
Q92793 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide CBP (V2427). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1078 CBP (V2427) pAb.
Blocking peptide available as BS1078PP