Product Name :
DNA-PKCS (R4090)Peptide Applications :
Blocking Background :
The PIKrelated kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3- and PI 4-kinases. DNA-PK is a heterotrimeric DNA binding enzyme that is composed of a large subunit, DNA-PKCS, and two smaller subunits collectively known as Ku. The loss of DNA-PK leads to defects in DSB repair and V(D)J recombination. FRAP can autophosphorylate on serine and bind to Rapamycin/FKBP. Alternative Name :
DNA PKcs; DNA-PK catalytic subunit; DNA-PKcs; EC 2.7.11.1; DNPK1; p460; DNA Pkcs; DNA dependent protein kinase. DNA PK cs. catalytic subunit Swiss-Prot :
P78527 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DNA-PKCS (R4090). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1092 DNA-PKCS (R4090)pAb.
DNA-PKCS (R4090)Peptide Applications :
Blocking Background :
The PIKrelated kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3- and PI 4-kinases. DNA-PK is a heterotrimeric DNA binding enzyme that is composed of a large subunit, DNA-PKCS, and two smaller subunits collectively known as Ku. The loss of DNA-PK leads to defects in DSB repair and V(D)J recombination. FRAP can autophosphorylate on serine and bind to Rapamycin/FKBP. Alternative Name :
DNA PKcs; DNA-PK catalytic subunit; DNA-PKcs; EC 2.7.11.1; DNPK1; p460; DNA Pkcs; DNA dependent protein kinase. DNA PK cs. catalytic subunit Swiss-Prot :
P78527 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide DNA-PKCS (R4090). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1092 DNA-PKCS (R4090)pAb.
Blocking peptide available as BS1092PP