ERα (H112) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ERα (H112) Peptide Applications :
Blocking Background :
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functionalcharacteristics. Alternative Name :
Estrogen receptor; ER-alpha; ER; ESR1; ESR; NR3A1 Swiss-Prot :
P03372 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ERα (H112). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1115 ERα (H112) pAb.
ERα (H112) Peptide Applications :
Blocking Background :
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functionalcharacteristics. Alternative Name :
Estrogen receptor; ER-alpha; ER; ESR1; ESR; NR3A1 Swiss-Prot :
P03372 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ERα (H112). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1115 ERα (H112) pAb.
Blocking peptide available as BS1115PP