F8 (S2194) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
F8 (S2194) Peptide Applications :
Blocking Background :
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and Factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A, or thrombin mediated proteolytic cleavage of Factor VII at Arg152-Ile153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing 2 EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels. Alternative Name :
Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component; F8C; Factor VIII; FactorVIII; Factor8; Factor 8; Factor-VIII; Factor-8 Swiss-Prot :
P00451 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide F8 (S2194). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1119 F8 (S2194) pAb.
F8 (S2194) Peptide Applications :
Blocking Background :
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and Factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A, or thrombin mediated proteolytic cleavage of Factor VII at Arg152-Ile153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing 2 EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels. Alternative Name :
Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component; F8C; Factor VIII; FactorVIII; Factor8; Factor 8; Factor-VIII; Factor-8 Swiss-Prot :
P00451 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide F8 (S2194). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1119 F8 (S2194) pAb.
Blocking peptide available as BS1119PP