mGluR-6 (A865) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
mGluR-6 (A865) Peptide Applications :
Blocking Background :
The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons. Alternative Name :
Metabotropic glutamate receptor 6; mGluR6; GRM6; GPRC1F; MGLUR6 Swiss-Prot :
O15303 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mGluR-6 (A865). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1146 mGluR-6 (A865) pAb.
mGluR-6 (A865) Peptide Applications :
Blocking Background :
The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons. Alternative Name :
Metabotropic glutamate receptor 6; mGluR6; GRM6; GPRC1F; MGLUR6 Swiss-Prot :
O15303 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide mGluR-6 (A865). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1146 mGluR-6 (A865) pAb.
Blocking peptide available as BS1146PP