Integrin β5 (V746) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Integrin β5 (V746) Peptide Applications :
Blocking Background :
Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16α and 8β subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many 、biological processes, including cell growth, differentiation, migration and apoptosis. Alternative Name :
Integrin beta-5; ITGB5 Swiss-Prot :
P18084 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Integrin β5 (V746). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1188 Integrin β5 (V746) pAb.
Integrin β5 (V746) Peptide Applications :
Blocking Background :
Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16α and 8β subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many 、biological processes, including cell growth, differentiation, migration and apoptosis. Alternative Name :
Integrin beta-5; ITGB5 Swiss-Prot :
P18084 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Integrin β5 (V746). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1188 Integrin β5 (V746) pAb.
Blocking peptide available as BS1188PP