IKB-ε (D17) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
IKB-ε (D17) Peptide Applications :
Blocking Background :
IkB-ε (I-kappa-B-epsilon), also known as NFKBIE (NFκB inhibitor epsilon) or IKBE, is a 500 amino acid protein that belongs to the NFκB inhibitor family. Localizing to the cytoplasm, IkB-ε is highly expressed in spleen, testis and lung, with lower levels of expression found in kidney, pancreas, heart, placenta, brain, granulocytes and macrophages. IkB-ε inhibits c-Rel and NFκB subunits p50, p52 and p65 by forming a complex with them in the cytoplasm, preventing them from activating genes in the nucleus. IkB-ε undergoes serine phosphorylation, resulting in the protein being marked for destruction via the ubiquitination pathway. Alternative Name :
NF-kappa-BIE; I-kappa-B-epsilon; IkB-E; IkB-epsilon; IkappaBepsilon; NFKBIE; IKBE; IkB ε; IkBε Swiss-Prot :
O00221 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IKB-ε (D17) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1191 IKB-ε (D17) pAb .
IKB-ε (D17) Peptide Applications :
Blocking Background :
IkB-ε (I-kappa-B-epsilon), also known as NFKBIE (NFκB inhibitor epsilon) or IKBE, is a 500 amino acid protein that belongs to the NFκB inhibitor family. Localizing to the cytoplasm, IkB-ε is highly expressed in spleen, testis and lung, with lower levels of expression found in kidney, pancreas, heart, placenta, brain, granulocytes and macrophages. IkB-ε inhibits c-Rel and NFκB subunits p50, p52 and p65 by forming a complex with them in the cytoplasm, preventing them from activating genes in the nucleus. IkB-ε undergoes serine phosphorylation, resulting in the protein being marked for destruction via the ubiquitination pathway. Alternative Name :
NF-kappa-BIE; I-kappa-B-epsilon; IkB-E; IkB-epsilon; IkappaBepsilon; NFKBIE; IKBE; IkB ε; IkBε Swiss-Prot :
O00221 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide IKB-ε (D17) . (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1191 IKB-ε (D17) pAb .
Blocking peptide available as BS1191PP