COPS3 (M408) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
COPS3 (M408) Peptide Applications :
Blocking Background :
The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes. The complex is made up of several widely expressed proteins: CSN1 (COPS1), CSN2 (COPS2), CSN3 (COPS3), CSN4 (COPS4), CSN5 (COPS5), CSN6 (COP6), CSN7a (COPS7, COPS7a) or CSN7b (COP7b) and CSN8 (COP8). The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes. It is also involved in the phosphorylation of p53, c-Jun, I˚Bα and IRF-8, as well as CSN-dependent phosphorylation of p53, and c-Jun protects and promotes degradation by the Ubl system. Alternative Name :
COP9 signalosome complex subunit 3; SGN3; Signalosome subunit 3; AB1-containing signalosome subunit 3; COPS 3; CSN3 Swiss-Prot :
Q9UNS2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide COPS3 (M408). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1192 COPS3 (M408) pAb.
COPS3 (M408) Peptide Applications :
Blocking Background :
The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes. The complex is made up of several widely expressed proteins: CSN1 (COPS1), CSN2 (COPS2), CSN3 (COPS3), CSN4 (COPS4), CSN5 (COPS5), CSN6 (COP6), CSN7a (COPS7, COPS7a) or CSN7b (COP7b) and CSN8 (COP8). The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes. It is also involved in the phosphorylation of p53, c-Jun, I˚Bα and IRF-8, as well as CSN-dependent phosphorylation of p53, and c-Jun protects and promotes degradation by the Ubl system. Alternative Name :
COP9 signalosome complex subunit 3; SGN3; Signalosome subunit 3; AB1-containing signalosome subunit 3; COPS 3; CSN3 Swiss-Prot :
Q9UNS2 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide COPS3 (M408). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1192 COPS3 (M408) pAb.
Blocking peptide available as BS1192PP