JunD (V249) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
JunD (V249) Peptide Applications :
Blocking Background :
The activator protein-1 (AP-1) transcription factor consists of either Jun/Jun homodimers or Fos/Jun heterodimeric complexes. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family. Studies suggest that the two forms of Jun D may be due to internal initiation of translation. Alternative Name :
JunD; JunD; 3727; JUND; 165162; P17535; Swiss-Prot :
P17535 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide JunD (V249). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1198 JunD (V249) pAb.
JunD (V249) Peptide Applications :
Blocking Background :
The activator protein-1 (AP-1) transcription factor consists of either Jun/Jun homodimers or Fos/Jun heterodimeric complexes. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family. Studies suggest that the two forms of Jun D may be due to internal initiation of translation. Alternative Name :
JunD; JunD; 3727; JUND; 165162; P17535; Swiss-Prot :
P17535 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide JunD (V249). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1198 JunD (V249) pAb.
Blocking peptide available as BS1198PP