LIMK1/2 (D402) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
LIMK1/2 (D402) Peptide Applications :
Blocking Background :
Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon. Alternative Name :
LIM domain kinase 1; LIMK-1; LIMK1; LIMK; LIM domain kinase 2; LIMK 2; LIMK2 Swiss-Prot :
P53667/P53671 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide LIMK1/2 (D402). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1215 LIMK1/2 (D402) pAb.
LIMK1/2 (D402) Peptide Applications :
Blocking Background :
Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon. Alternative Name :
LIM domain kinase 1; LIMK-1; LIMK1; LIMK; LIM domain kinase 2; LIMK 2; LIMK2 Swiss-Prot :
P53667/P53671 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide LIMK1/2 (D402). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1215 LIMK1/2 (D402) pAb.
Blocking peptide available as BS1215PP