RARβ (L359) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
RARβ (L359) Peptide Applications :
Blocking Background :
Retinoids are metabolites of vitamin A (retinol) that are important signaling molecules during vertebrate development and tissue differentiation. Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are nuclear transcription factors that modulate the effects of retinoids (RA) on gene expression. Most retinoid forms (including all trans RA, 9-cis RA, 4oxo RA and 3,4 dihydro RA) activate RAR family members, whereas RXR family members are activated by 9-cis-RA only. RA binds RARs, inducing a change in receptor configuration that allows DNA binding and increased gene transcription from specific genes to occur. RAR family members, which include RARα, RARβ and RARγ, belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Retinoid receptor expression is tissue specific; the skin expresses RARγ and RXRα. Alternative Name :
RARB; HAP; NR1B2; RAR-BETA; RAR-EPSILON; RRB2 Swiss-Prot :
P10826 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RARβ (L359). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1315 RARβ (L359) pAb.
RARβ (L359) Peptide Applications :
Blocking Background :
Retinoids are metabolites of vitamin A (retinol) that are important signaling molecules during vertebrate development and tissue differentiation. Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are nuclear transcription factors that modulate the effects of retinoids (RA) on gene expression. Most retinoid forms (including all trans RA, 9-cis RA, 4oxo RA and 3,4 dihydro RA) activate RAR family members, whereas RXR family members are activated by 9-cis-RA only. RA binds RARs, inducing a change in receptor configuration that allows DNA binding and increased gene transcription from specific genes to occur. RAR family members, which include RARα, RARβ and RARγ, belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Retinoid receptor expression is tissue specific; the skin expresses RARγ and RXRα. Alternative Name :
RARB; HAP; NR1B2; RAR-BETA; RAR-EPSILON; RRB2 Swiss-Prot :
P10826 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide RARβ (L359). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1315 RARβ (L359) pAb.
Blocking peptide available as BS1315PP