Product Name :
Rit1 (W204) Peptide Applications :
Blocking Background :
ROC 1 and ROC 2 are the two highly conserved RING finger proteins that are homologous to APC 11, a subunit of the anaphase promoting complex(APC). ROC 1 and ROC 2 commonly interact with all cullins while APC 11 specifically interacts with APC 2, a cullin related APC subunit. ROC 1 and APC 11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1 and E2 dependent manner. ROC 1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin 1 to catalyze ubiquitin polymerization. Alternative Name :
RIT1; MGC125864; MGC125865; RIBB; RIT; ROC1 Swiss-Prot :
Q92963 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Rit1 (W204). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1317 Rit1 (W204) pAb.
Rit1 (W204) Peptide Applications :
Blocking Background :
ROC 1 and ROC 2 are the two highly conserved RING finger proteins that are homologous to APC 11, a subunit of the anaphase promoting complex(APC). ROC 1 and ROC 2 commonly interact with all cullins while APC 11 specifically interacts with APC 2, a cullin related APC subunit. ROC 1 and APC 11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1 and E2 dependent manner. ROC 1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin 1 to catalyze ubiquitin polymerization. Alternative Name :
RIT1; MGC125864; MGC125865; RIBB; RIT; ROC1 Swiss-Prot :
Q92963 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Rit1 (W204). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1317 Rit1 (W204) pAb.
Blocking peptide available as BS1317PP