MEK-4/ MAP2K4 (E74) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
MEK-4/ MAP2K4 (E74) Peptide Applications :
Blocking Background :
The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway. Alternative Name :
MAP2K4; EC 2.7.12.2; JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SEK1; SERK1 Swiss-Prot :
P45985 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MEK-4/ MAP2K4 (E74). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1320 MEK-4/ MAP2K4 (E74) pAb.
MEK-4/ MAP2K4 (E74) Peptide Applications :
Blocking Background :
The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway. Alternative Name :
MAP2K4; EC 2.7.12.2; JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SEK1; SERK1 Swiss-Prot :
P45985 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide MEK-4/ MAP2K4 (E74). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1320 MEK-4/ MAP2K4 (E74) pAb.
Blocking peptide available as BS1320PP