SNAP 25 (E183) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
SNAP 25 (E183) Peptide Applications :
Blocking Background :
Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF(N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synap-totagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and Synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including α- and γ-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis bycompeting with SNAP 25 and syntaxins for VAMP binding. Alternative Name :
SNAP25; BA416N4.2; DJ1068F16.2; FLJ23079; RIC-4; RIC4; SNAP; SNAP-25; SUP Swiss-Prot :
P60880 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SNAP 25 (E183). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1327 SNAP 25 (E183) pAb.
SNAP 25 (E183) Peptide Applications :
Blocking Background :
Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF(N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synap-totagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and Synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including α- and γ-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis bycompeting with SNAP 25 and syntaxins for VAMP binding. Alternative Name :
SNAP25; BA416N4.2; DJ1068F16.2; FLJ23079; RIC-4; RIC4; SNAP; SNAP-25; SUP Swiss-Prot :
P60880 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SNAP 25 (E183). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1327 SNAP 25 (E183) pAb.
Blocking peptide available as BS1327PP