Syk (L519) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Syk (L519) Peptide Applications :
Blocking Background :
Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigenesis. Two isoforms of Syk, designated short and long, exist due to alternative splicing events. Alternative Name :
Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk; SYK Swiss-Prot :
P43405 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Syk (L519). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1344 Syk (L519) pAb.
Syk (L519) Peptide Applications :
Blocking Background :
Syk (spleen tyrosine kinase) is a 635 amino acid protein that contains one protein kinase domain and two SH2 domains. One of several members of the protein kinase superfamily, Syk functions as a positive effector of B cell antigen receptor (CD79)-stimulated responses, coupling CD79 with the movement of one calcium ion through one of two phospho-regulated pathways. Via its ability to influence CD79 activity and to control the movement of calicum through the cell, Syk plays an important role in a variety of cellular responses, including differentiation, phagocytosis, proliferation and B cell development. Syk expression is upregulated in T cell lymphoma, suggesting a possible role for Syk in tumorigenesis. Two isoforms of Syk, designated short and long, exist due to alternative splicing events. Alternative Name :
Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk; SYK Swiss-Prot :
P43405 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Syk (L519). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1344 Syk (L519) pAb.
Blocking peptide available as BS1344PP