TGFβ2 (L388) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
TGFβ2 (L388) Peptide Applications :
Blocking Background :
Transforming growth factor betas (TGFβs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFα. It is now realized that TGFβs mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGFβ1, TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFβ requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFβ3 protein has approximately 80% identity to the mature region of both TGFβ1 and TGFβ2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. Alternative Name :
TGFB2; CETERMIN; G-TSF; MGC116892; POLYERGIN; TGF-BETA-2; TGF-BETA2 Swiss-Prot :
P61812 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TGFβ2 (L388). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1362 TGFβ2 (L388) pAb.
TGFβ2 (L388) Peptide Applications :
Blocking Background :
Transforming growth factor betas (TGFβs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFα. It is now realized that TGFβs mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGFβ1, TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFβ requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFβ3 protein has approximately 80% identity to the mature region of both TGFβ1 and TGFβ2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. Alternative Name :
TGFB2; CETERMIN; G-TSF; MGC116892; POLYERGIN; TGF-BETA-2; TGF-BETA2 Swiss-Prot :
P61812 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide TGFβ2 (L388). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1362 TGFβ2 (L388) pAb.
Blocking peptide available as BS1362PP