VaV1 (A168) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
VaV1 (A168) Peptide Applications :
Blocking Background :
The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins; deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. Alternative Name :
Proto-oncogene vav; VAV Swiss-Prot :
P15498 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide VaV1 (A168). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1370 VaV1 (A168) pAb.
VaV1 (A168) Peptide Applications :
Blocking Background :
The Vav gene was originally identified on the basis of its oncogenic activation during the course of gene transfer assays. The major translational product of the Vav proto-oncogene has been identified as a protein containing an array of structural motifs. Contained within its amino terminus are a helix-loop-helix domain and a leucine zipper motif similar to that of Myc family proteins; deletion of this region of p95Vav causes its oncogenic activation. In addition, p95Vav contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of p95Vav is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. Alternative Name :
Proto-oncogene vav; VAV Swiss-Prot :
P15498 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide VaV1 (A168). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1370 VaV1 (A168) pAb.
Blocking peptide available as BS1370PP