BACE (D492) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
BACE (D492) Peptide Applications :
Blocking Background :
Autosomal dominant Alzheimer’s disease is caused by mutations in the gene encoding the β-amyloid protein precursor (APP). Amyloid β-peptide(Aβ), the major feature of amyloid plaques in Alzheimer’s patients, is the product of APP cleavage by β- and γ-secretases. BACE is the transmembrane protease which cleaves Aβ from APP. BACE and the related protein Asp1 are both widely expressed in human tissue with the highest levels in the pancreas. BACE has a molecular mass of ~70 kDa, larger than predicted due to glycosylation, and is localized within Golgi and endosomes. Alternative Name :
BACE1; ASP2; BACE; EC 3.4.23.46; FLJ90568; HSPC104; KIAA1149; MEMAPSIN-2 Swiss-Prot :
P56817 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BACE (D492). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1382 BACE (D492) pAb.
BACE (D492) Peptide Applications :
Blocking Background :
Autosomal dominant Alzheimer’s disease is caused by mutations in the gene encoding the β-amyloid protein precursor (APP). Amyloid β-peptide(Aβ), the major feature of amyloid plaques in Alzheimer’s patients, is the product of APP cleavage by β- and γ-secretases. BACE is the transmembrane protease which cleaves Aβ from APP. BACE and the related protein Asp1 are both widely expressed in human tissue with the highest levels in the pancreas. BACE has a molecular mass of ~70 kDa, larger than predicted due to glycosylation, and is localized within Golgi and endosomes. Alternative Name :
BACE1; ASP2; BACE; EC 3.4.23.46; FLJ90568; HSPC104; KIAA1149; MEMAPSIN-2 Swiss-Prot :
P56817 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide BACE (D492). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1382 BACE (D492) pAb.
Blocking peptide available as BS1382PP