Product Name :
Dynamin-1 (V768) Peptide Applications :
Blocking Background :
Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression in testis. Both Dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the Dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to Clathrin coated pits by SH3 domain interaction with Amphiphysin, a protein highly expressed in brain. Alternative Name :
Dynamin 1; Dynamin1; DNM1; DNM; Dynamin I; Dynamin-I; DynaminI Swiss-Prot :
Q05193 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Dynamin-1 (V768). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1396 Dynamin-1 (V768) pAb.
Dynamin-1 (V768) Peptide Applications :
Blocking Background :
Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression in testis. Both Dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the Dynamins and effectors of their GTPase activity. The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to Clathrin coated pits by SH3 domain interaction with Amphiphysin, a protein highly expressed in brain. Alternative Name :
Dynamin 1; Dynamin1; DNM1; DNM; Dynamin I; Dynamin-I; DynaminI Swiss-Prot :
Q05193 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Dynamin-1 (V768). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1396 Dynamin-1 (V768) pAb.
Blocking peptide available as BS1396PP