SAE1 (L247) Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
SAE1 (L247) Peptide Applications :
Blocking Background :
Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteosome. Ubiquitin-like 1-activating enzyme E1A, also designated SUMO-1-activating enzyme or AOS-1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. It can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. Alternative Name :
SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; SAE1; AOS1; SUA1; UBLE1A Swiss-Prot :
Q9UBE0 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SAE1 (L247). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1457 SAE1 (L247) pAb.
SAE1 (L247) Peptide Applications :
Blocking Background :
Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteosome. Ubiquitin-like 1-activating enzyme E1A, also designated SUMO-1-activating enzyme or AOS-1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. It can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. Alternative Name :
SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; SAE1; AOS1; SUA1; UBLE1A Swiss-Prot :
Q9UBE0 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SAE1 (L247). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1457 SAE1 (L247) pAb.
Blocking peptide available as BS1457PP