Product Name :
SENP2 (L512) Peptide Applications :
Blocking Background :
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates. Alternative Name :
Sentrin-specific protease 2; Sentrin/SUMO-specific protease SENP2; SMT3-specific isopeptidase 2; Smt3ip2; Axam2; KIAA1331 Swiss-Prot :
Q9HC62 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SENP2 (L512). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1470 SENP2 (L512) pAb.
SENP2 (L512) Peptide Applications :
Blocking Background :
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates. Alternative Name :
Sentrin-specific protease 2; Sentrin/SUMO-specific protease SENP2; SMT3-specific isopeptidase 2; Smt3ip2; Axam2; KIAA1331 Swiss-Prot :
Q9HC62 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide SENP2 (L512). (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS1470 SENP2 (L512) pAb.
Blocking peptide available as BS1470PP